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FOGSI HIV PEP
HELPLINE
Dr.Narendra Malhotra
FOGSI coordinator for PEP Helpline
Dr. Alok Vashishtha
Consultant in Infectious Diseases
Haridwar
What is Post exposure
prophylaxis for HIV ?
Exposure


OCCUPATIONAL EXPOSURE that may
place a worker at risk of HIV infection is a
percutaneous injury ,contact of mucous
membrane or contact of skin (especially when
the skin is chapped, abraded or affected with
dermatitis or the contact is prolonged or
involves an extensive area ) with blood tissue or
other body fluids to which universal precautions
apply.
Institute of Infectious Diseases
Why this helpline ?
Why this helpline ?






The needle stick injury can not only lead to some life
threatening blood borne infections as well as have
severe emotional impact on health care personnel.
It is an medical emergency and can happen anywhere
anytime
FOGSI initiative is first of its kind in world

Institute of Infectious Diseases
What is the extent of the problem ?


Survey of 428 HCW in India
- 343 (80%) had 1 PI in past 1
year (IJMR, April,2010)



In USA there are 57 documented
cases of health care workers
contracting
HIV
from
exposures; 137 other possible
cases
(NEJM 2003;348:826)

Institute of Infectious Diseases
Rationale of PEP
Information about primary HIV infection

indicate that systemic infection does not occur
immediately leaving a brief period within ‘window
of opportunity’ during which post exposure antiretroviral intervention may modify viral replicaiton

Institute of Infectious Diseases
Principle behind administering PEP

Surface ligands of
dendritic cells of skin
or mucous membrane

CD4 CELL
Institute of Infectious Diseases
WHAT TO DO ON EXPOSURE


It is a medical emergency



Do not panic

Institute of Infectious Diseases
WHAT NEXT


REPORT PROMPTLY



PEP MUST START AT THE EARLIEST
PREFERABLY WITHIN TWO HOURS
 MAY BE UPTO 72 HOURS


Institute of Infectious Diseases
How to assess risk ?
The exposure report
(Each exposure is unique)
•






Date and time of exposure
Accurate report: Minute to minute details are ideal
Procedure details…what, where, how, with what
device
Exposure details...route, body substance involved,
volume/duration of contact
Information about source person and exposed
person
Exposure management details
Institute of Infectious Diseases
Launch of HELPLINE
International Conference of HIV and Women
16 November, 2008, Nagpur
How does HELPLINE work ?
How helpline works








A call is received from an exposed health care
worker by Dr Alok Vashishtha, Specialist in
HIV/AIDS on his cell. He then follows
following procedure:
Details of exposure are taken
A protocol is decided
ARV drugs are made available (if required)
Follow up is done as decided
Have a team of resource persons for complex
scenarios
How drugs are made available








Have a memorandum of understanding with all
companies making and marketing HIV drugs.
Dr Alok Vashishtha have the mobile numbers of
National Sales manager of all companies in field
of HIV therapy.
Their pan India sales network of about 2500
executives is used to locate the pharmacy
catering these drugs.
Address is given to the exposed health care
provider
Type of calls








Call from around all states of India
Call from Asia, Africa, Europe and USA.
Problem phone calls (General query about
HIV/AIDS)
Special kind of exposures
Missed calls
Stigma calls
For locating a OBGYN
Conclusions







Health care workers put themselves at risk in their work
Prevention of exposures is critical
PEP can be useful intervention
Management of occupational exposure is complex
Expert consultation should be sought
Finally
Awareness of Universal precautions and PEP options:
- allay fears of caring for HIV infected persons
- reduced stigma and discrimination
- better care of PLHIV

Institute of Infectious Diseases
HELP LINE TEAM
Dr. Narendra Malhotra
 Dr. C.N. Purandare
 Dr. Laxmi Shrikhande
 Dr .Alok Vashistha
ACKNOWLEDGEMENTS
 All FOGSI Members


www.fogsi.org
Prevention is better than cure

Institute of Infectious Diseases
Thank You for your kind attention

Institute of Infectious Diseases
Nirmal Medical Foundation, Hardwar
Institute of Infectious Diseases

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HIV-PEP HELPLINE FOR HEALTH PROFFESSIONALS

  • 1. FOGSI HIV PEP HELPLINE Dr.Narendra Malhotra FOGSI coordinator for PEP Helpline Dr. Alok Vashishtha Consultant in Infectious Diseases Haridwar
  • 2. What is Post exposure prophylaxis for HIV ?
  • 3. Exposure  OCCUPATIONAL EXPOSURE that may place a worker at risk of HIV infection is a percutaneous injury ,contact of mucous membrane or contact of skin (especially when the skin is chapped, abraded or affected with dermatitis or the contact is prolonged or involves an extensive area ) with blood tissue or other body fluids to which universal precautions apply. Institute of Infectious Diseases
  • 5. Why this helpline ?    The needle stick injury can not only lead to some life threatening blood borne infections as well as have severe emotional impact on health care personnel. It is an medical emergency and can happen anywhere anytime FOGSI initiative is first of its kind in world Institute of Infectious Diseases
  • 6. What is the extent of the problem ?  Survey of 428 HCW in India - 343 (80%) had 1 PI in past 1 year (IJMR, April,2010)  In USA there are 57 documented cases of health care workers contracting HIV from exposures; 137 other possible cases (NEJM 2003;348:826) Institute of Infectious Diseases
  • 7.
  • 8. Rationale of PEP Information about primary HIV infection indicate that systemic infection does not occur immediately leaving a brief period within ‘window of opportunity’ during which post exposure antiretroviral intervention may modify viral replicaiton Institute of Infectious Diseases
  • 9. Principle behind administering PEP Surface ligands of dendritic cells of skin or mucous membrane CD4 CELL Institute of Infectious Diseases
  • 10. WHAT TO DO ON EXPOSURE  It is a medical emergency  Do not panic Institute of Infectious Diseases
  • 11. WHAT NEXT  REPORT PROMPTLY  PEP MUST START AT THE EARLIEST PREFERABLY WITHIN TWO HOURS  MAY BE UPTO 72 HOURS  Institute of Infectious Diseases
  • 12. How to assess risk ? The exposure report (Each exposure is unique) •      Date and time of exposure Accurate report: Minute to minute details are ideal Procedure details…what, where, how, with what device Exposure details...route, body substance involved, volume/duration of contact Information about source person and exposed person Exposure management details Institute of Infectious Diseases
  • 13. Launch of HELPLINE International Conference of HIV and Women 16 November, 2008, Nagpur
  • 14.
  • 16. How helpline works       A call is received from an exposed health care worker by Dr Alok Vashishtha, Specialist in HIV/AIDS on his cell. He then follows following procedure: Details of exposure are taken A protocol is decided ARV drugs are made available (if required) Follow up is done as decided Have a team of resource persons for complex scenarios
  • 17. How drugs are made available     Have a memorandum of understanding with all companies making and marketing HIV drugs. Dr Alok Vashishtha have the mobile numbers of National Sales manager of all companies in field of HIV therapy. Their pan India sales network of about 2500 executives is used to locate the pharmacy catering these drugs. Address is given to the exposed health care provider
  • 18.
  • 19. Type of calls        Call from around all states of India Call from Asia, Africa, Europe and USA. Problem phone calls (General query about HIV/AIDS) Special kind of exposures Missed calls Stigma calls For locating a OBGYN
  • 20. Conclusions       Health care workers put themselves at risk in their work Prevention of exposures is critical PEP can be useful intervention Management of occupational exposure is complex Expert consultation should be sought Finally Awareness of Universal precautions and PEP options: - allay fears of caring for HIV infected persons - reduced stigma and discrimination - better care of PLHIV Institute of Infectious Diseases
  • 21. HELP LINE TEAM Dr. Narendra Malhotra  Dr. C.N. Purandare  Dr. Laxmi Shrikhande  Dr .Alok Vashistha ACKNOWLEDGEMENTS  All FOGSI Members  www.fogsi.org
  • 22. Prevention is better than cure Institute of Infectious Diseases
  • 23. Thank You for your kind attention Institute of Infectious Diseases Nirmal Medical Foundation, Hardwar Institute of Infectious Diseases

Editor's Notes

  1. {"12":"It is important to collect and record information about the exposure on an exposure report, and to maintain the confidentiality of both the worker and the source patient. An exposure report should include the date and time that the exposure occurred, as well as details of what procedure was being performed, where, how, and what device (if any) was involved. If a device was involved, OSHA requires that the brand and manufacturer of the device be recorded. Details such as the route of exposure, body substance involved, and volume or duration of contact also should be included. Additionally, information about the source person and exposed person, if known, is critical, along with exposure management details, which will be discussed later.\n"}