The document compares three data serialization protocols: Protocol Buffers (protobuf), Apache Thrift, and Avro, discussing their design goals, efficiency, ease of use, and performance. It highlights each protocol's strengths, weaknesses, and typical use cases, emphasizing Protocol Buffers for its speed and third-party support, Thrift for its extensive language support and RPC implementation, and Avro for its schema-based system and integration with Hadoop. The author concludes that the choice of protocol depends on specific application requirements and programming language support.