The document describes the patient recruitment services offered by In-Site, a division of WCCT Global. In-Site utilizes the latest technologies to expedite enrollment timelines for clinical research programs. Their full-service customizable solution includes patient identification, social media targeting, branding/ad creation, real-time appointment scheduling, retention applications, website development, and more. In-Site aims to improve enrollment rates and patient retention through their recruitment workflow and data-driven approach.

1. Patient Recruitment
Capabilities

2. Patient Identification System
Cloud Based RetentionApplication
Social Media
Targeting
Branding and AdCreation
Real-TimeAppointment
Scheduling
SMS
Follow-Up Email Marketing
Site Reputation
Enhancement
Website Development
Mobile-Friendly Patient
Sign-UpApplication
SEO Services
Physician RelationsTeam
In-HouseCall Center
WCCTGLOBAL’S PATIENT RECRUITMENT DIVISION, IN-SITE, UTILIZESTHE MOST UP-TO-DATE
TECHNOLOGIESAVAILABLETOTHE INDUSTRYTO EXPEDITE ENROLLMENTTIMELINES. IN-SITE OFFERSA
FULLY-CUSTOMIZABLESERVICETHATCAN BE IMPLEMENTEDWITH ANY RESEARCH PROGRAM. IN-SITE’S
SERVICESCAN BE USED FOR ANY PATIENT POPULATION NEARLYANYWHERE ONTHE GLOBE.
PATIENT RECRUITMENT DIVISION
IN-SITE

3. PATIENT RECRUITMENT DIVISION
IN-SITE

4. In-Site Services

5. PATIENT RETENTION APPLICATION
Keep patients informed with real-time
updates and study-related reminders using
enhanced geo-targeting
Ensure protocol adherence, appointment
scheduling, and active participation
Distribute Study-related information or
tasks via mobile platform
Give patients the option to report Adverse
Events round-the-clock
Allow patients to sign documents
electronically, reducing potential drop-off
because of travel time and site visits
WCCT GLOBAL HAS DEVELOPEDA PATIENT RETENTION PLATFORMTO
ACCOMPANY IN-SITEWHICH HAS INCREASED RETENTION & ENGAGEMENT BY UP
TO 40% IN SOME RESEARCH PROGRAMS. BY IMPLEMENTINGTHIS CUTTING-EDGE
PLATFORM, SITESWILL BEABLETO:

6. • Data is provided by:
• Claims clearinghouses
• Electronic Medical Record Providers
• Independent PhysicianAssociations
• Pharmacy Benefit Management Providers
• Our system can help to:
• Identify the best locations for study sites
• Show the geographic areas with the most
patients in
your desired indication
• Provide data on how far patients are
willing to travel for treatment
SEARCH FORAND LOCATEYOUR DESIRED PATIENT POPULATIONSWITHWCCT
GLOBAL’S PROPRIETARY PATIENT IDENTIFICATION SYSTEM.THIS SYSTEM
LOCATES PATIENTS BASEDON ICD-9 CODESAND MEDICAL DATA.
PATIENT IDENTIFICATION

7. • Specialized Social Media
RecruitmentTargeting by:
• Age
• Gender
• Interest
• Location
• Lifestyle
• Disease State
• Creates a completely “opt-in”
database of potential volunteers
for your study.
SOCIAL MEDIA IS A POWERFULTOOL FOR IDENTIFYING PATIENTS IN NEARLY ANY
INDICATION, IN NEARLY ANY LOCATION INTHEWORLD.WCCT GLOBAL MAKES
USE OFTHISTOOLTO QUICKLY FIND QUALIFIED PATIENTSAND ENROLLYOUR
STUDY.
SOCIAL MEDIA TARGETING

8. • WCCT studies the conversations that your desired patient population is having in the
digital sphere and translates these conversations into advertisements that will appeal
to these patients and friends, family, and caregivers.
SOPHISTICATED DESIGNTEAMTHAT USES DATA FROM PATIENT NETWORKSTO
DEVELOP PROPER MESSAGING FOR PATIENT ENGAGEMENT.
BRANDING & AD CREATION

9. POTENTIAL PATIENT
INPUTS DATA
IMMEDIATE EMAIL/
SMS FOLLOW-UP
24/7 CALL CENTER
SCHEDULING
REAL-TIME APPOINTMENT
SCHEDULING
IN-SITE’S 24/7 IN-HOUSECALL CENTER IS CAPABLE OF SCHEDULING
APPOINTMENTS IN REAL-TIMEAT MULTIPLE STUDY SITES, USINGANY
SCHEDULING SERVICEOR PROCEDURE.

10. SMS FOLLOW-UP & EMAIL MARKETING
New Paid Studies for You and Your Loved Ones!
Sent to 7,449 subscribers in “Study 1” at 08/28/15 09:34 AM PST
1.2k
opened
Brand New Paid Volunteer Studies to Check Out!
Sent to 5,058 subscribers in “Study 2” at 08/26/15 10:33 AM PST Includes 2 additional lists
1.4k
opened
Brand New Paid Volunteer Studies to Check Out!
Sent to 7,843 subscribers in “Study 3” at 08/25/15 09:52 AM PST Includes 1 additional lists
2k
opened
IMMEDIATE EMAIL /
SMS FOLLOW-UP

11. PHYSICIAN RELATIONS
IN-SITE HAS ACCESSTO A LARGE DATABASEOF INVESTIGATORSAND SITESTHAT
CAN HELP SPONSORS MAKE DECISIONS REGARDINGTHEIR PROGRAM INTHE
FOLLOWINGTHERAPEUTICAREAS:
• Allergy & Asthma
• Immunology
• Cardiology
• Cardiovascular-
electrophysiology
• Internal Medicine
• Dermatology
• Gastroenterology
• Nephrology & HTN
• Obstetrics/Gynecology
• Pulmonology
• Rheumatology
• Plastic Surgery
• Geriatrics
INVESTIGATORS
SITES

12. 24/7 IN-HOUSE CALL CENTER
WCCT GLOBAL OFFERSA ROUND-THE-CLOCK CALL CENTER SERVICE FOR CLINICAL
TRIAL PATIENT RECRUITMENTAND SCREENING.WE’VE RECRUITED AND SCREENED
PATIENTS FOR OVER 4,000 RESEARCH PROGRAMSTHROUGH OUR CLINICALTRIAL
CALL CENTER ALONE!
• HIPAA compliant
• USA based with 24/7
international reach
• Multilingual (English, Spanish,
Japanese, Korean, Chinese, &
Vietnamese) to screen/recruit
for Ethnobridging studies
• Capable of conducting patient pre-
screening and patient scheduling
• Service customizable for any
protocol
• 100% accurate data collection
from calls
• Recruitment and retention for
Phase I-IV studies
WCCT CLINICALTRIAL CALL CENTER DETAILS:

13. WEBSITE DEVELOPMENT & SEO
SERVICES
RESPONSIVELY-DESIGNEDWEBSITES FOR LONG-TERM, LATE PHASECLINICALTRIALS.
• Central location for all study-related
information
• Presents an easily-accessible method for
potential patients to reach out for more
information
• Online location for study-sign up
• Adds more authority to your study and
makes study more personable and
approachable by online visitors
• Integrated process to drive organic
traffic to study-specific websites for
increased exposure
• Easy linking to social media channels
being used to advertise your study and
encourage engagement with patients
Benefits of creating a study-specific website:

14. SITE REPUTATION ENHANCEMENT
IMPROVES SITE REPUTATION IN PATIENTS’VIEWPOINTTHROUGH REVIEW SITES
LIKEYELP, GOOGLE PLACES,AND FACEBOOK.

15. MOBILE-FRIENDLY PATIENT APPLICATION
AFTER CLICKINGTHROUGH AN ADVERTISEMENT, POTENTIAL PATIENTSWILL BE
REDIRECTED TO A MOBILE-FRIENDLY, PATIENT APPLICATION PAGE WHERETHEY CAN
“OPT-IN”TO RECEIVE MORE INFORMATION ABOUTYOUR PROGRAM. CONTACT
INFORMATION IS STORED IN A SECURE DATABASE.
Targeted Advertisement Patient Application Page

16. Recruitment
CampaignWorkflow

17. WORKFLOW OVERVIEW
IN-SITEWILL CREATE A UNIQUE RECRUITMENTCAMPAIGNTHAT ISTAILOREDTO
YOUR RESEARCH PROGRAMAND DESIRED PATIENT POPULATION.WHILEYOUR
SPECIFIC RECRUITMENTCAMPAIGN MAY INCLUDE OTHER IN-SITE SERVICES,OUR
STANDARD RECRUITMENTCAMPAIGN INCLUDESTHE FOLLOWING ELEMENTS
THAT HAVE BEEN PROVENTO GENERATEQUALIFIED PATIENTS FOR RESEARCH
PROGRAMS:
Enrollment
PredictionAnalytics Enrollment
Appointment Scheduling
Follow-Up & Pre-Screening
Patient Referral Generation
Social Media Listening
Ad Creation & Placement

18. ENROLLMENT PREDICTION ANALYTICS
IN-SITEWILL COMPILE INFORMATION FROM MULTIPLE DATA POINTS, INCLUDING
OUR PATIENT IDENTIFICATION SYSTEM, SOCIAL MEDIA, KEYWORD SEARCHES,
AND REPORTS FROM 3RD PARTY CLINICALTRIAL ADVERTISEMENTVENDORSTO
PREDICTA NUMBER OF ENROLLED SUBJECTS PER SITE PER MONTH.
2,000 referrals
70-80
patients
National Multi-SiteCampaign

19. ENROLLMENT PREDICTION ANALYTICS
50 referrals
2-3
patients
Regional Multi-SiteCampaign
Single Site Campaign
600 referrals
20-25
patients

20. DIGITAL MEDIA LISTENING
BEFORE LAUNCHING ANY DIGITAL RECRUITMENTCAMPAIGN, IN-SITEWILL
CONDUCT IN-DEPTH RESEARCHONTHETYPES OF CONVERSATIONSYOUR
DESIRED PATIENT POPULATION IS PARTICIPATING INON SOCIAL MEDIA, BLOGS,
FORUMS,AND INTHEIR SEARCHES.WEWILL LEVERAGETHIS DATATO CREATE
ADVERTISEMENTSTHAT WILL APPEALTOTHIS AUDIENCEAND ENCOURAGE
PARTICIPATION INYOUR RESEARCH PROGRAM.

21. AD CREATION & PLACEMENT
AFTER CREATING APPEALINGADVERTISEMENTSAND SUBMITTING FOR IRB
APPROVAL, IN-SITEWILL PLACETARGETED ADVERTISEMENTSONTHE MOST
EFFECTIVECHANNELS FORYOUR INDICATION.

22. PATIENT REFERRAL GENERATION
IMMEDIATELYAFTERYOUR CAMPAIGN’SADVERTISEMENTS BEGIN CIRCULATING
ON NUMEROUS DIGITALVENUES,WEWILL BEGIN RECEIVING PATIENT
REFERRALS FROM 100% ‘OPT-IN’ SIGN-UPSONYOUR CAMPAIGN’S UNIQUE
PATIENTAPPLICATION.CONTACT INFORMATION IS STORED IN A SECURE
DATABASEAND ACCESSIBLE IN REAL-TIME.THE REFERRAL ISTHEN PLACED INTO
OUR PROPRIETARY PATIENTTRACKING SYSTEM.

23. FOLLOW UP & PRE-SCREENING
A DEDICATEDTEAM FROM IN-SITE’S IN-HOUSECALL CENTERWILL BE
RESPONSIBLE FOR FOLLOW-UPWITH ALL PATIENT REFERRALSTHAT ARE
CREATED. OUR RECRUITMENT SPECIALISTSWILL CONDUCT AN IRB-APPROVED
PHONE SCREENTO DETERMINE ELIGIBILITY FOR PARTICIPATION. IF ELIGIBLE,THE
REFERRALWILL BE SCHEDULED FORAN APPOINTMENTATYOUR SITE.
SCHEDULED SCREENING
DNQ

24. APPOINTMENT SCHEDULING
IN-SITE’S RECRUITMENT SPECIALISTSWILL ADAPTTO ANY SCHEDULING SERVICE
OR PROCEDURE USED AT ANY SITE, INCLUDING GOOGLECALENDAR, ACUITY
SCHEDULING, SCHEDULEONCE,AND MORE.

25. ENROLLMENT
IN-SITEWILL ONLY SEND QUALIFIED LEADSTOYOUR SITE(S), BASEDONYOUR
PROTOCOL’S INCLUSION/EXCLUSIONCRITERIAAND PRE-SCREENINGCONDITIONS.
FROMTHESEAPPOINTMENTS,YOU CAN EXPECTTO SEE SUBJECTS RANDOMIZED
INTOYOUR PROGRAM!
• Risk-Free Enrollment:
• IN-SITE offers a pay-per-patient-
randomized model to eliminate risk for
sites and sponsors…Only pay when a
patient is successfully enrolled within the
protocol of your program!
Randomized

26. Additional Recruitment
Capabilities & Services

27. CAPABILITIES & SERVICES
ADDITIONAL RECRUITMENT
IN ADDITIONTO OUR STANDARD RECRUITMENT SERVICES, IN-SITE IS CAPABLE OF
AIDING PROGRAMS INTHE FOLLOWINGAREAS:
Multi-Site Management
Global NHV Recruitment
Rare Disease Recruitment

28. MULTI-SITE MANAGEMENT
POTENTIAL PATIENTCONTACT INFORMATION ISAUTOMATICALLY SORTED BY
LOCATION, MAKING IT EASYTO MANAGE PATIENT REFERRALS FROM MULTIPLE
LOCATIONSAND SENDTHEMTOTHE CORRECT SITE INYOUR PROGRAM.
POTENTIAL PATIENT
INPUTS DATA
SITEA
SITE B
SITE C
INFORMATION FORWARDED
TO APPROPRIATE SITE

29. GLOBAL NVH RECRUITMENT
WHILEWCCT GLOBAL ISTHE PREMIERECRO IN RECRUITING NORMAL HEALTHY
VOLUNTEERS INTHE SOUTHERNCALIFORNIA REGION, IN-SITE’SCAPABILITIES
ALLOWWCCT GLOBALTO RECRUIT NORMAL HEALTHYVOLUNTEERS FROMANY
REGION INTHE UNITED STATES FOR PHASE 1 STUDIES.
IN-SITE Process for Global NHV Recruitment:
• Create visually-appealing advertisements with trial-
specific information for use on Web, Print, & Digital
Radio
• Place targeted advertisements directed at Healthy
Volunteers in any US region
• Coordinate with site to identify schedule for study
visits
• Conduct phone screen with potential volunteers
• Schedule study visits in real-time using Cloud-Based
scheduling

30. GLOBAL NVH RECRUITMENT
1 Month Recruitment Campaign:
• Delivered targeted advertisements to over 5,500 viewers online
• Generated 600 potential study subject referrals
• Contacted over 500 potential study subjects
• Scheduled over 70 Appointments
• Enrolled over 30 subjects = 5% Enrollment Rate
Referrals Contacted Appointments Enrolled
600 500+ 70+ 30+
MATCHING STUDY CONDUCTED IN NEW YORK CITY LOOKING FOR NORMAL
HEALTHY VOLUNTEERS AGES 13-21 TO PARTICIPATE AS CONTROL GROUP FOR AN
ADOLESCENT RESPIRATORY & MENTAL HEALTH EVALUATION FOLLOWING THE
ATTACKS OF 9/11

31. RARE DISEASE RECRUITMENT
BECAUSE OF LOW PREVALENCEAND SCATTERED PATIENT POPULATIONS,
RECRUITING PATIENTS FOR RARE DISEASES IS ESPECIALLY DIFFICULT. HOWEVER,
IN-SITEOFFERSA NUMBEROF SERVICESTO HELP RECRUIT PATIENTS FOR EVEN
THE MOST RARE DISEASES.
Rare Disease
Recruitment Strategies:
• Study-specific,
multilingual websites
• Creation of online
patient communities
for patient/caregiver
interaction and
engagement
• Targeted keyword and
social media

32. STATISTICS & ANALYTICS
IN-SITE PERFORMANCE
• 95% of IN-SITE patient referrals generated by digital advertising
in any recruitment campaign
• 93% of IN-SITE patient referrals generated within first 60 days of
recruitment campaign or less
• 97% overall retention rate
• Avg. 67% of all patients enrolled for entire program were through
IN-SITE generated patient referrals
• Improves retention and engagement rates by up to 37%
• 100% of patient referrals are followed up with within 48 hours
• Call Center can schedule up to 100 appointments in a single day

33. BY THERAPEUTIC AREA
PATIENT RECRUITMENT SUCCESS
IN-SITECAN BE USED FORANY PATIENT POPULATION
ASTHMA/ALLERGY
OPHTHALMOLOGY
IMMUNOLOGY
INFECTIOUS DISEASE
NEUROLOGY
CV/METABOLIC
ONCOLOGY
NEPHROLOGY
HEPATOLOGY
ETHNOBRIDGING