Paras Gupta is seeking a career in toxicology. He has over 2 years of experience conducting toxicity studies and 5 months experience in quality control. He holds an M.Pharmacy in Pharmacology and has experience with acute, sub-chronic and chronic toxicity studies, various routes of animal dosing, necropsy, and validating studies. He is currently a research scientist at Dabur Research Foundation conducting repeated dose toxicity studies in rats.

1. PARAS GUPTA
Permanent Add: A-377 Anand Nagar, Bahodapur, Gwalior, Madhya Pradesh, India.
Mob no: 07566656222
Home: 07512497634
E-Mail: paras.guptarx@gmail.com
CAREER OBJECTIVE:
To add innovative ideas to the work, I do for achieving the organizational goal and to
have a continuous self-development by way of learning and exposure to new
assignments.
AREA OF SPECIALIZATION:
M. PHARMACY (Pharmacology)
CAREER INTEREST:
1) Toxicology.
SUMMARY OF SKILLS:
 M. Pharma (Pharmacology) has acquired extensive conceptual knowledge and
experience in Research and development, Project Handling & laboratory operations.
 Experience of more than 25 months in Toxicology/Preclinical and also having 5
months experience in Quality Control (Projects Handling & Laboratory operations).
 A flexible & detail oriented attitude with an ability to work independently as well as
part of a multidisciplinary team.
 An out of the box thinker having problem solving & organizational abilities.
ACADEMIC / TECHNICAL CREDENTIALS:
 M. PHARMACY (Pharmacology) 66% - 2011
I.S.F. College of Pharmacy, Moga, Under- Punjab Technical University, Jalandhar
(Punjab)
 B.PHARMACY 67% - 2009
Shree Ram College of Pharmacy, Banmore, Under- Rajiv Gandhi Technical University,
Bhopal
 INTERMEDIATE 66% M.P Board - 2005
EXPERENCE:
Dabur Research Foundation, Ghaziabad (Uttar Pradesh): March 2015 - At
Present
Designation: Research scientist
Job Responsibilities:
 Performing Sub Chronic & Chronic Toxicological studies as per Principles of OECD and
Schedule Y-India.
 Repeated 180 days Dermal Toxicity Study in Rat.
 Repeated Dose 28 days Oral Toxicity studies in Rats.

2.  Repeated Dose 14 days Sub-cutaneous Toxicity studies in Rats.
 Performing day to day activity related to Toxicological Studies.
 Preparation of Standard Operating Procedure, Study Reports, Study Plans,
Archiving, etc.
 Various Routes of Dosing in Rats.
 Euthanasia, Blood collection and Necropsy of Rats.
 Performing exercises for Dose Formulation, Body Weight, Feed intake, Organ
Weight, Test Item/Chemical Weighing, etc.
 Performing other activities related to study and other laboratory operations.
 Involved in validation of Acute, Sub-Chronic and Chronic Toxicity Studies for GLP
Submission.
Jai Research Foundation, Vapi (Gujarat): Feb 2014 - March
2015
Designation: Jr. Research Officer (Study Personal).
Job Responsibilities:
 Performed Acute Toxicological studies mentioned below, as per Principles of OECD-
Good Laboratory Practice.
 Acute Oral Toxicity Studies in Laboratory Rats and Mice.
 Acute Dermal Toxicity Studies in Laboratory Rats.
 Guinea pig skin sensitization study by Guinea Pig Maximization Test and Buehler
Test method.
 Acute Eye and Dermal Irritation/Corrosion in Rabbits.
 Inhalation Toxicity Study in Laboratory Rats.
 Performed day to day activity related to toxicological studies.
 Involved in Preparation of Study Reports, Study Plans, Archive, etc.
 Various Routes of Dosing in Rat, Mice and Guinea pig.
 Recorded of Body Weight, Temperature, Humidity, etc.
 Performed other activities related to study and laboratory operations.
 Also completed the GLP validation of Bovine Corneal Opacity and Permeability Test.
Amol Pharmaceuticals, Jaipur (RJ): Aug 2012 - Jan 2013
Designation: Jr. Chemist in Department of Quality control.
Job responsibilities:
 Analyze sample for its quality and stability.
 Performed analysis on analytical instruments like (UV, ICP, AAS, Dissolution test
apparatus, HPLC).
 Performed qualitative analysis, preparation & reviewing documents for the same
sample.
OTHER RESEARCH SKILLS:
Brief detail of Methods and Techniques used:
 Experienced in Animal Handling and Dosing (by Various Route of Drug
Administration).
 Performed Blood Collection Techniques in Rodents and Non-Rodents by (Retro Orbital
Sinus, Heart Puncture, Tail Vein and Sublingual Vein and by Marginal Ear Vein).
 Extracted of Plant Extract.
 Recorded Blood Pressure in Anaesthetized Dog.

3.  Recorded Blood Pressure, Heart Rate and Coronary Effluent in Rats using Langendorff
Apparatus.
 Intra cerebro ventricular (ICV) Cannulation and Dosing in Rats using Stereotaxic
Apparatus.
 Assessed Infract Size and Ulcer Index.
 Induced Neuropathic Pain by Sciatic Nerve Ligation method.
 Recorded Non-Invasive Blood Pressure by Tail-Cuff method.
 Cotton-Pellet Induced Granuloma for Chronic Inflammation.
 Pylorus ligation for Assessment of Ulcer.
 Hepatic Artery Ligation for Assessment of Hepatic Ischemia.
 Bile Duct Ligation and Cannulation for Assessment of Hepatic Damage.
 Both Right and Left Carotid Artery Ligation for Global CNS Ischemia.
 Jugular Vein and Femoral Vein Cannulation for Blood Sampling & Drug
Administration.
 Disease models: Conceptual and practical knowledge of In-Vivo Pharmacological
Animal Models and Techniques in CNS, CVS, GIT, Oncology, Respiratory,
Inflammation/Pain and Metabolic disorders.
Instruments handled:
 NIBP- Biopac MP 100 [USA].
 UV-Visible Spectrophotometer (Perkin Elmer).
 Gas Chromatograph.
 Inductive Coupled Plasma Spectrophotometer (ICP).
 Atomic Adsorption Spectroscopy.
 Bio-Pac system for ECG, Pressure & Force measurement of heart.
 Rotaroad Apparatus.
 Actophotometer for measurement of CNS activity.
 Plethysmograph for measurement of paw oedema.
 Planter test Apparatus. (UGO – Basile).
 REMI-CPR30 Cooling Centrifuge.
Computer proficiency:
 Proficient in use of Computer Systems Particularly Microsoft Office T ools (Word,
Excel, PowerPoint, publisher, etc.), Adobe Acrobat, Corel Draw, Graph Pad Prism
Capable of retrieving information from Internet and Various research related
Database.
PUBLICATIONS:
1) Paras Gupta1, Rohit Goyal2*, Yamini Chauhan2 and Pyare Lal sharma1. Possible
Modulation of FAS and PTP-1B Signaling in Ameliorative Potential of Bombax ceiba
against High Fat Diet Induced Obesity. BMC Complementary and Alternative Medicine
2013, 13:281, doi: 10. 1186/1472-6882-13-281.
2) Paras Gupta*, Sandeep Tyagi, Minky Mukhija, Arminder Singh Saini, Rohit Goyal,
Pyare Lal Sharma. Obesity: An Introduction and Evaluation. Journal of Advanced
Pharmacy Education & Research. 2011, 2, 125-137, ISSN 2249-3379.
3) Sandeep Tyagi, Paras Gupta, Arminder Singh Saini, Chaitnya Kaushal, Saurabh
Sharma. The peroxisome proliferators-activated receptor: A family of nuclear
receptors role in various diseases. Journal of Advanced Pharmaceutical Technology &
Research. 2011, 2, 4, 236-240.

4. RESEARCH PROJECTS:
1) Title: The Effect of Bombax Ceiba Linn. against Experimental Obesity in wistar rats
under kind supervision of Prof. P. L. Sharma and co-supervision of Dr. Rohit Goyal.
Role: Project Associate.
Description: The study was carried out in High fat diet treated rats at 3 different
doses regimen. In this study Parameters was evaluated; Anthropometric parameters,
Free fatty acid level (FFA), Serum lipid & hepatic markers, Tissue biochemical
markers and Histological study was done to check the efficacy of the drug. On the
basis of the results obtained in present study, it may be concluded that the
methanolic extract of Bombax ceiba Linn. has significant anti-obesity potential
against HFD induced experimental obesity, possibly due to modulation of FAS and
PTP-1B signaling in rat.
2) Title: The Ameliorative Potential of Bombax Ceiba Linn. against Experimental
Hypertension in wistar rats under Kind supervision of Prof. P.L. Sharma and co-
supervision of Dr. Rohit Goyal.
Role: Project Associate.
Description: This study was carried out in two different models; HFD induced
Hypertension and DOCA salt induced Hypertension. In these study parameters was
evaluated; Systolic-Diastolic blood pressure, Anthropometric parameters and Serum
Biochemical markers was done to check the effectiveness of drug. After the
completion of study all results showing that the extract of Bombay CIBA Linn. having
Anti-Hypertensive Potential on two different doses.
PERSONAL DOSSIER:
Name : Paras Gupta Marital Status : Single
Father’s Name : Mr. J. P. Gupta Sex : Male
Mother’s Name : Mrs. Manju Lata Gupta Nationality : Indian
Date of Birth : 16th June. 1987 Languages Known : English & Hindi
Declaration: I hereby declare that all the above information given by me is true to my
consent.
Signature:
(PARAS GUPTA)