This document is a resume for Amarish Kumar Sharma, an Indian biotech professional with over 6 years of research experience in drug discovery and development. His experience includes assay development, toxicity studies, high-throughput screening, and research projects related to diabetes, stem cells, and drug screening. He has worked as a research scientist and assistant professor and holds an MTech and BTech in Biotechnology from Bundelkhand University in India.
Spectroscopic Characterization of Chloramphenicol and Tetracycline: An Impact...Mahendra Kumar Trivedi
The present study was aimed to evaluate the impact of biofield treatment for spectroscopic characterization of chloramphenicol and tetracycline using FT-IR and UV-Vis spectroscopy.Methods: The study was performed in two groups (control and treatment) of each antibiotic. The control groups remained as untreated, and biofield treatment was given to treatment groups.
Spectroscopic Characterization of Chloramphenicol and Tetracycline: An Impact...Mahendra Kumar Trivedi
The present study was aimed to evaluate the impact of biofield treatment for spectroscopic characterization of chloramphenicol and tetracycline using FT-IR and UV-Vis spectroscopy.Methods: The study was performed in two groups (control and treatment) of each antibiotic. The control groups remained as untreated, and biofield treatment was given to treatment groups.
2. PROFESSIONAL EDUCATION
Investigated the effect of Hepatocyte Nuclear Factor-4α phosphorylation and its transactivation and assessing AMPK activation in Hepatocytes on Type 2 Diabetes assay model.
Assessed the effect of cationic amphiphilic drugs induced Phospholipidosis and their in-vitro high throughput screening (HTS) in CHO-K1 cell line using the fluorescent-labelled phospholipid probe.
Standardized the bio-assay for the analysis of Nephrotoxicity (ADME/Tox) in HEK-293 cell lines and in-vitro screening of the NCE’s (New Chemical Entities) on induced Type 2 Diabetic assay model.
Investigated the relationship between IMTG (Intramuscular triglycerides) and Insulin resistance in Obese Type 2 Diabetic in-vitro model on C2C12 cell line followed by high throughput screening of new chemical entities for its respective efficacy.
Investigated the effect of HSD11b1 mediated Endoplasmic Reticulum stress (ADME/Tox) on Type 2 Diabetic invitro model using C2C12 cell line.
Studied the expression of CPT1A gene and ECHS1 gene which play a major role in accumulation of fat in the liver and is associated with insulin resistance and type 2 diabetes mellitus followed by high throughput in-vitro screening of new chemical entity for its efficacy.
University teaching of subjects namely Stem Cell Technology & Animal Biotechnology, Administrative responsibilities (Pedagogy development, Training, workshop & seminar organization).
Guided & co-ordinated graduate and post-graduate interns in project work concerned to Heavy metal Bioremediation and Food Bio-preservatives.
POST-GRADUATE INTERNSHIP: August 2007 - January 2008 (6 months)
Project title:
▪ “Bioactivity guided fractionation and in-vitro screening of MHCO2 isolated from marine bacteria showing Anti-Diabetic Activity ".
▪ Investigated the anti-hyperglycaemic effect of different plant metabolic extracts and extracts derived from marine source for their efficacy in glucose uptake in skeletal muscles through an in-vitro assay model using radio-labelled glucose and L6 cell line (skeletal muscles isolated from Rat),at Department of Biotechnology
August 2006-December 2007
Master of Technology (M.Tech) in Biotechnology
Bundelkhand University, INDIA
July 2002 - July 2006
Bachelor of Technology (B.Tech) in Biotechnology
Bundelkhand University, INDIA
Research & Development | Drug discovery program