pancreatitis .docx
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Pancreatitis can cause both systemic and local complications. Systemic complications result from enzymes and inflammatory molecules released by the inflamed pancreas, which can damage blood vessels and cause low blood pressure, fast heart rate, blood clots, and organ failure. Locally, the pancreas can digest itself through autodigestion and necrosis, leading to pseudocysts and abscesses that can compress and infect nearby structures. Inflammation is often due to gallstones or alcohol and can progress to affect the entire body.
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Quality assurance B.pharm 6th semester BP606T UNIT 5
Quality assurance B.pharm 6th semester BP606T UNIT 5
11.1 Role of physical biological in deterioration of grains.pdf
11.1 Role of physical biological in deterioration of grains.pdf
Clinical periodontology and implant dentistry 2003.pdf
Clinical periodontology and implant dentistry 2003.pdf
Holsinger, Bruce W. - Music, body and desire in medieval culture [2001].pdf
Holsinger, Bruce W. - Music, body and desire in medieval culture [2001].pdf
Gadgets for management of stored product pests_Dr.UPR.pdf
Gadgets for management of stored product pests_Dr.UPR.pdf
Nutaceuticsls herbal drug technology CVS, cancer.pptx
Nutaceuticsls herbal drug technology CVS, cancer.pptx
Sexuality - Issues, Attitude and Behaviour - Applied Social Psychology - Psyc...
Sexuality - Issues, Attitude and Behaviour - Applied Social Psychology - Psyc...
Introduction_Ch_01_Biotech Biotechnology course .pptx
Introduction_Ch_01_Biotech Biotechnology course .pptx
pancreatitis .docx
- 1. Pancreatitis Systemic complications in acute pancreatitis reflect the pancreatic gland's ability to produce proteases, lipases and kinins liberated from the inflamed pancreas. Local complications can be manifested by pancreatic autodigestion and in varied degrees necrosis. The development of pancreatic pseudocysts can compress adjacent structures and obstruct their function, and abscesses can cause infections and leucocytosis. Inflammation within acinar cells is frequently initiated by gallstones or alcohol and may progress to systemic inflammation. Vasodilation and increased blood vessel permeability result in blood pressure drop and tachycardia. Coagulation abnormalities assumed to be initiated by cytokines and trypsin range from microvascular thrombosis to disseminated intravascular coagulation. Myocardial depression, haemorrhage and hypovolemic shock are thought to be secondary to the enzymatic degradation of vessels. Pre-renal acute kidney injury has been explained on the basis of decreased glomerular filtration rate.