nursing management of a patient with painancychacko89
This document discusses pain, including definitions, types, theories, assessment, and management. It defines pain as a sensory and emotional experience associated with tissue damage. There are different types of pain such as acute, chronic, neuropathic, and nociceptive. Theories discussed include specificity theory, pattern theory, and gate control theory. Pain is influenced by many factors and should be assessed using various scales tailored for different populations. Management includes pharmacological approaches like the WHO analgesic ladder as well as non-pharmacological options. Nurses play an important role in comprehensive pain assessment.
Providing quality pediatric pain management during end of life carecassidydanielle
Author: Danielle Cassidy, PharmD, BCPS
Audience: continuing education for hospice nurses
Background: describes common developmentally appropriate tools for assessing pain in children, general principles of pediatric pharmacology, common pharmacological interventions, side effects commonly associated with opioid medications & side effect management strategies.
This document summarizes guidelines for managing acute perioperative pain in infants and children. It discusses pain assessment tools, non-pharmacological approaches like regional anesthesia, and pharmacological options including acetaminophen, NSAIDs, gabapentin, ketamine, dexmedetomidine, and opioids. It emphasizes the need for multimodal analgesia, risk-based dosing due to developmental differences, and close monitoring for sedation and respiratory depression when using opioids in this vulnerable population.
Se revisa las técnicas para evaluar el dolor, como varios sistemas de puntuación del dolor específicos por edad. Se discute el manejo farmacológico del dolor, incluyendo el uso de agentes que inhiben la formación de prostaglandinas, AINES y el acetaminofeno, así como los opioides débiles usados comúnmente, cuando la administración oral es factible, para el tratamiento del dolor leve a moderado.
Awareness and assessment of the pain in
postoperative children is important
Remember the different pharmacology in
neonates, infants and children
Multi-modal approach to preventing and treating
pain to minimize adverse effects
Regional analgesia must be considered unless
contraindicated
This document provides an overview of pain management in children. It defines pain, discusses barriers to treatment, and consequences of untreated pain. Assessment tools like the Wong-Baker Faces scale are presented. A variety of pharmacological and non-pharmacological interventions are reviewed. The World Health Organization principles of pediatric acute pain management are outlined, emphasizing a multimodal approach, regular dosing, and individualizing treatment based on the child's needs. Opioids are discussed along with considerations of tolerance, dependence, and addiction.
This document discusses nursing management of pain. It defines pain, describes types of pain such as acute and chronic pain, and the physiology of pain including transduction, transmission, modulation and perception. It also discusses factors affecting pain, assessment of pain using subjective and objective methods, pharmacological management with non-opioid and opioid analgesics, and non-pharmacological approaches. The roles and interventions of nurses in comprehensive pain management are outlined.
Basics in pain management IN PEDIATRIC patientsAyman264741
This document summarizes guidelines and research on pain management in pediatric emergency departments. It discusses myths around pediatric pain perception, ethical considerations, pain assessment tools for different age groups, procedural sedation and analgesia guidelines, topical and oral analgesics. Key points covered include that neonates can perceive pain, inadequate pain management can have long-term effects, opioids do not mask symptoms in acute abdominal pain, and sucrose has been shown to reduce pain in neonates undergoing minor invasive procedures.
nursing management of a patient with painancychacko89
This document discusses pain, including definitions, types, theories, assessment, and management. It defines pain as a sensory and emotional experience associated with tissue damage. There are different types of pain such as acute, chronic, neuropathic, and nociceptive. Theories discussed include specificity theory, pattern theory, and gate control theory. Pain is influenced by many factors and should be assessed using various scales tailored for different populations. Management includes pharmacological approaches like the WHO analgesic ladder as well as non-pharmacological options. Nurses play an important role in comprehensive pain assessment.
Providing quality pediatric pain management during end of life carecassidydanielle
Author: Danielle Cassidy, PharmD, BCPS
Audience: continuing education for hospice nurses
Background: describes common developmentally appropriate tools for assessing pain in children, general principles of pediatric pharmacology, common pharmacological interventions, side effects commonly associated with opioid medications & side effect management strategies.
This document summarizes guidelines for managing acute perioperative pain in infants and children. It discusses pain assessment tools, non-pharmacological approaches like regional anesthesia, and pharmacological options including acetaminophen, NSAIDs, gabapentin, ketamine, dexmedetomidine, and opioids. It emphasizes the need for multimodal analgesia, risk-based dosing due to developmental differences, and close monitoring for sedation and respiratory depression when using opioids in this vulnerable population.
Se revisa las técnicas para evaluar el dolor, como varios sistemas de puntuación del dolor específicos por edad. Se discute el manejo farmacológico del dolor, incluyendo el uso de agentes que inhiben la formación de prostaglandinas, AINES y el acetaminofeno, así como los opioides débiles usados comúnmente, cuando la administración oral es factible, para el tratamiento del dolor leve a moderado.
Awareness and assessment of the pain in
postoperative children is important
Remember the different pharmacology in
neonates, infants and children
Multi-modal approach to preventing and treating
pain to minimize adverse effects
Regional analgesia must be considered unless
contraindicated
This document provides an overview of pain management in children. It defines pain, discusses barriers to treatment, and consequences of untreated pain. Assessment tools like the Wong-Baker Faces scale are presented. A variety of pharmacological and non-pharmacological interventions are reviewed. The World Health Organization principles of pediatric acute pain management are outlined, emphasizing a multimodal approach, regular dosing, and individualizing treatment based on the child's needs. Opioids are discussed along with considerations of tolerance, dependence, and addiction.
This document discusses nursing management of pain. It defines pain, describes types of pain such as acute and chronic pain, and the physiology of pain including transduction, transmission, modulation and perception. It also discusses factors affecting pain, assessment of pain using subjective and objective methods, pharmacological management with non-opioid and opioid analgesics, and non-pharmacological approaches. The roles and interventions of nurses in comprehensive pain management are outlined.
Basics in pain management IN PEDIATRIC patientsAyman264741
This document summarizes guidelines and research on pain management in pediatric emergency departments. It discusses myths around pediatric pain perception, ethical considerations, pain assessment tools for different age groups, procedural sedation and analgesia guidelines, topical and oral analgesics. Key points covered include that neonates can perceive pain, inadequate pain management can have long-term effects, opioids do not mask symptoms in acute abdominal pain, and sucrose has been shown to reduce pain in neonates undergoing minor invasive procedures.
What is pain
Understand the different types of pain
How to assess pain through visual scales
Know how to initiate pain medications
Learn to reassess pain and modify treatment strategies
pain mangement Lecture for 3rd year MBBSNadir Mehmood
This document provides an overview of pain control and postoperative analgesia. It begins with defining different types of pain such as nociceptive and neuropathic pain. It then discusses factors that influence pain and the physiological and psychological effects of uncontrolled pain. The document outlines principles of pain assessment and various pain assessment tools. It discusses pharmacological and non-pharmacological pain control strategies including the WHO analgesic ladder and principles of multimodal analgesia. The document provides details on specific drug classes and routes of administration for pain management. It concludes with discussing a multidisciplinary approach to pain management.
This document provides guidance on clinical development of new pain medications. It discusses general considerations like pharmacokinetic and dose response studies. It recommends study designs for exploring efficacy in acute and chronic pain, including appropriate patient populations, endpoints, and trial duration. Safety evaluation over long term use is also addressed. Special populations like children, elderly, and those with renal or hepatic impairment require tailored study approaches.
Unrelieved pain can have negative physiological effects. It prolongs the stress response and causes harmful changes to the endocrine, cardiovascular, respiratory, immune, and other body systems. Assessing pain in all patients, including those who cannot self-report, is important for effective pain management. A comprehensive pain assessment evaluates location, intensity, quality, onset/duration, relieving/aggravating factors, function, goals, and other details. Non-pharmacological and pharmacological methods are both used to treat pain, and opioids carry side effects like respiratory depression that require monitoring.
This study examined the effect of Swedish massage on sleep quality and quantity in hospitalized children aged 4-12 years. 70 children were randomly assigned to a control or massage group. The massage group received 30 minutes of Swedish massage nightly for 3 nights. Sleep quality was measured using the CSHQ questionnaire completed by parents, and sleep quantity was measured via daily logs. Massage significantly improved scores on all CSHQ subscales and total sleep quality, but did not significantly impact sleep quantity. The study concluded that massage is an effective non-pharmacological intervention to improve children's sleep quality during hospitalization.
Pain is a complex, multidimensional experience that is always subjective. It is defined as "an unpleasant sensory and emotional experience associated with actual or potential tissue damage." There are several types of pain including nociceptive, neuropathic, acute, chronic, and cancer pain. Pain should be assessed using scales like the numeric scale or Wong-Baker FACES scale to evaluate severity and impact. Unrelieved pain can have adverse effects physically, psychologically, and on quality of life. A multidimensional approach to pain management includes both pharmacological and non-pharmacological strategies to treat pain, maintain function, and enhance well-being.
This document discusses optimizing pain management in cancer treatment. It provides an overview of concepts like total pain, the WHO analgesic ladder for treating pain with opioids, and the importance of proper pain assessment and documentation. The key points are:
1) Total pain includes physical, psychosocial, emotional, and spiritual suffering experienced by cancer patients.
2) The WHO analgesic ladder recommends treating mild pain with non-opioids like paracetamol, moderate pain with weak opioids like codeine, and severe pain with strong opioids like morphine.
3) Proper pain assessment involves documenting pain scores, characteristics, causes, and impact on function to effectively guide pain treatment decisions.
This document discusses optimizing pain management in cancer treatment. It provides an overview of concepts like total pain, the WHO analgesic ladder for treating pain with opioids, and the importance of proper pain assessment and documentation. The key points are:
1) Total pain includes physical, psychosocial, emotional, and spiritual suffering experienced by cancer patients.
2) The WHO analgesic ladder recommends treating mild pain with non-opioids like paracetamol, moderate pain with weak opioids like codeine, and severe pain with strong opioids like morphine.
3) Proper pain assessment involves documenting pain scores, characteristics, causes, and impact on function to effectively guide pain treatment decisions.
The document discusses pain in preterm and term neonates. It states that the pain system is intact and functional in both populations. Behavioral responses like facial expressions and cry characteristics can indicate pain. The development of sensory receptors and connections allow pain to be processed by 20 weeks gestation. While neonatal pain may not be recalled, it can have long term impacts on brain development and later health and behavior. Effective pain assessment and management are important to provide neonatal patients.
This document provides an overview of acute pain management in children. It discusses the difficulties in assessing and treating pain in children, as well as the physiological and behavioral effects of acute pain. General principles for managing acute pain in children include anticipating and preventing pain, adequately assessing pain using age-appropriate tools, using a multi-modal approach including pharmacological and non-pharmacological therapies, involving parents, and using non-noxious routes of medication administration when possible. Specific pharmacological therapies for acute pain in children such as acetaminophen, NSAIDs, opioids, and local anesthetics are also reviewed.
This document discusses pain management in pediatric patients. It begins by presenting two case studies and then outlines objectives to understand different types of pain, how to initiate pain medications, and how to assess pain and modify treatment strategies. It describes nociceptive and neuropathic pain. It emphasizes the need to constantly re-assess pain plans, outlines tools for assessing pain in infants and verbal children, and provides guidance on both non-pharmacologic and pharmacologic pain management strategies and medications. Key takeaways include the importance of using an age-appropriate assessment tool, considering around-the-clock regimens, continually re-assessing pain and treatment plans, and guidelines for when to call the attending or transfer to a higher level
Dr. Fatma Al-Dammas is an anesthesiology professor and director of the anesthesia and acute/chronic pain management programs. She specializes in managing pain, which requires a multidisciplinary team approach. The goals of pain treatment are to improve quality of life, facilitate recovery, reduce morbidity, and allow for early hospital discharge. Pain management involves both pharmacological and non-pharmacological approaches, including the WHO pain ladder and various methods of drug delivery like epidural analgesia. Epidural analgesia provides effective post-operative pain relief, improves pulmonary function, and enables earlier ambulation.
The document discusses neonatal pain, including that babies can feel and react to pain, validated scales exist to measure neonatal pain, and developmental aspects of pain perception in newborns. It also outlines non-pharmacological and pharmacological approaches to treating pain in newborns, emphasizing the need for comprehensive pain management strategies that minimize unnecessary pain in neonates.
Pain is a distressing feeling often caused by intense or damaging stimuli. The International Association for the Study of Pain's widely used definition defines pain as "an unpleasant sensory and emotional experience associated with actual or potential tissue damage, or described in terms of such damage"
NURSE
EDUCATION
MANAGEMENT
NURSING CARE
NURSING ASSESSMENT
PLANNING
At the end of the session he students will be able to
Explain the activities of health care agencies
List out the types of health care agencies.
Classify the types of service
INTERVENTION
OBJECTIVES
LEARNING
IMPLEMENTATION
EVALUATION
RATIONALE
At the end of this session the leaner should be able to,
define pain.
classify pain.
describe mechanism of pain.
perform pain assessment.
detail the nursing interventions.
Development of manpower resources
Provision for safe water and food supply
Increasing the literacy rate
Reducing the levels of poverty
Chronic pain management involves comprehensive evaluation and treatment of pain. The IASP defines chronic pain as pain persisting beyond normal tissue healing time, usually 3 months. It impacts function and well-being. Treatment includes pharmacotherapy like opioids, nonopioids, and adjuvant analgesics. Opioids require careful patient selection, dosing, monitoring, and side effect management. Adjuvant analgesics like anticonvulsants and antidepressants are effective for neuropathic pain. A multimodal approach balances analgesia and side effects for optimal chronic pain treatment.
SpAn harus memberi waktu untuk pengelolaan nyeri
SpAn harus mampu mengelola nyeri dengan memilih cara yang paling aman, paling efektif dan paling ekonomis
Berperan aktif pada acute pain
Berperan, minimal partisipatif, dalam chronic pain
Berperan utama pada interventional pain management
Osvaldo Bernardo Muchanga-GASTROINTESTINAL INFECTIONS AND GASTRITIS-2024.pdfOsvaldo Bernardo Muchanga
GASTROINTESTINAL INFECTIONS AND GASTRITIS
Osvaldo Bernardo Muchanga
Gastrointestinal Infections
GASTROINTESTINAL INFECTIONS result from the ingestion of pathogens that cause infections at the level of this tract, generally being transmitted by food, water and hands contaminated by microorganisms such as E. coli, Salmonella, Shigella, Vibrio cholerae, Campylobacter, Staphylococcus, Rotavirus among others that are generally contained in feces, thus configuring a FECAL-ORAL type of transmission.
Among the factors that lead to the occurrence of gastrointestinal infections are the hygienic and sanitary deficiencies that characterize our markets and other places where raw or cooked food is sold, poor environmental sanitation in communities, deficiencies in water treatment (or in the process of its plumbing), risky hygienic-sanitary habits (not washing hands after major and/or minor needs), among others.
These are generally consequences (signs and symptoms) resulting from gastrointestinal infections: diarrhea, vomiting, fever and malaise, among others.
The treatment consists of replacing lost liquids and electrolytes (drinking drinking water and other recommended liquids, including consumption of juicy fruits such as papayas, apples, pears, among others that contain water in their composition).
To prevent this, it is necessary to promote health education, improve the hygienic-sanitary conditions of markets and communities in general as a way of promoting, preserving and prolonging PUBLIC HEALTH.
Gastritis and Gastric Health
Gastric Health is one of the most relevant concerns in human health, with gastrointestinal infections being among the main illnesses that affect humans.
Among gastric problems, we have GASTRITIS AND GASTRIC ULCERS as the main public health problems. Gastritis and gastric ulcers normally result from inflammation and corrosion of the walls of the stomach (gastric mucosa) and are generally associated (caused) by the bacterium Helicobacter pylor, which, according to the literature, this bacterium settles on these walls (of the stomach) and starts to release urease that ends up altering the normal pH of the stomach (acid), which leads to inflammation and corrosion of the mucous membranes and consequent gastritis or ulcers, respectively.
In addition to bacterial infections, gastritis and gastric ulcers are associated with several factors, with emphasis on prolonged fasting, chemical substances including drugs, alcohol, foods with strong seasonings including chilli, which ends up causing inflammation of the stomach walls and/or corrosion. of the same, resulting in the appearance of wounds and consequent gastritis or ulcers, respectively.
Among patients with gastritis and/or ulcers, one of the dilemmas is associated with the foods to consume in order to minimize the sensation of pain and discomfort.
PGx Analysis in VarSeq: A User’s PerspectiveGolden Helix
Since our release of the PGx capabilities in VarSeq, we’ve had a few months to gather some insights from various use cases. Some users approach PGx workflows by means of array genotyping or what seems to be a growing trend of adding the star allele calling to the existing NGS pipeline for whole genome data. Luckily, both approaches are supported with the VarSeq software platform. The genotyping method being used will also dictate what the scope of the tertiary analysis will be. For example, are your PGx reports a standalone pipeline or would your lab’s goal be to handle a dual-purpose workflow and report on PGx + Diagnostic findings.
The purpose of this webcast is to:
Discuss and demonstrate the approaches with array and NGS genotyping methods for star allele calling to prep for downstream analysis.
Following genotyping, explore alternative tertiary workflow concepts in VarSeq to handle PGx reporting.
Moreover, we will include insights users will need to consider when validating their PGx workflow for all possible star alleles and options you have for automating your PGx analysis for large number of samples. Please join us for a session dedicated to the application of star allele genotyping and subsequent PGx workflows in our VarSeq software.
More Related Content
Similar to PAIN MANAGEMENT AND DRUG DILUTION PPT .pptx
What is pain
Understand the different types of pain
How to assess pain through visual scales
Know how to initiate pain medications
Learn to reassess pain and modify treatment strategies
pain mangement Lecture for 3rd year MBBSNadir Mehmood
This document provides an overview of pain control and postoperative analgesia. It begins with defining different types of pain such as nociceptive and neuropathic pain. It then discusses factors that influence pain and the physiological and psychological effects of uncontrolled pain. The document outlines principles of pain assessment and various pain assessment tools. It discusses pharmacological and non-pharmacological pain control strategies including the WHO analgesic ladder and principles of multimodal analgesia. The document provides details on specific drug classes and routes of administration for pain management. It concludes with discussing a multidisciplinary approach to pain management.
This document provides guidance on clinical development of new pain medications. It discusses general considerations like pharmacokinetic and dose response studies. It recommends study designs for exploring efficacy in acute and chronic pain, including appropriate patient populations, endpoints, and trial duration. Safety evaluation over long term use is also addressed. Special populations like children, elderly, and those with renal or hepatic impairment require tailored study approaches.
Unrelieved pain can have negative physiological effects. It prolongs the stress response and causes harmful changes to the endocrine, cardiovascular, respiratory, immune, and other body systems. Assessing pain in all patients, including those who cannot self-report, is important for effective pain management. A comprehensive pain assessment evaluates location, intensity, quality, onset/duration, relieving/aggravating factors, function, goals, and other details. Non-pharmacological and pharmacological methods are both used to treat pain, and opioids carry side effects like respiratory depression that require monitoring.
This study examined the effect of Swedish massage on sleep quality and quantity in hospitalized children aged 4-12 years. 70 children were randomly assigned to a control or massage group. The massage group received 30 minutes of Swedish massage nightly for 3 nights. Sleep quality was measured using the CSHQ questionnaire completed by parents, and sleep quantity was measured via daily logs. Massage significantly improved scores on all CSHQ subscales and total sleep quality, but did not significantly impact sleep quantity. The study concluded that massage is an effective non-pharmacological intervention to improve children's sleep quality during hospitalization.
Pain is a complex, multidimensional experience that is always subjective. It is defined as "an unpleasant sensory and emotional experience associated with actual or potential tissue damage." There are several types of pain including nociceptive, neuropathic, acute, chronic, and cancer pain. Pain should be assessed using scales like the numeric scale or Wong-Baker FACES scale to evaluate severity and impact. Unrelieved pain can have adverse effects physically, psychologically, and on quality of life. A multidimensional approach to pain management includes both pharmacological and non-pharmacological strategies to treat pain, maintain function, and enhance well-being.
This document discusses optimizing pain management in cancer treatment. It provides an overview of concepts like total pain, the WHO analgesic ladder for treating pain with opioids, and the importance of proper pain assessment and documentation. The key points are:
1) Total pain includes physical, psychosocial, emotional, and spiritual suffering experienced by cancer patients.
2) The WHO analgesic ladder recommends treating mild pain with non-opioids like paracetamol, moderate pain with weak opioids like codeine, and severe pain with strong opioids like morphine.
3) Proper pain assessment involves documenting pain scores, characteristics, causes, and impact on function to effectively guide pain treatment decisions.
This document discusses optimizing pain management in cancer treatment. It provides an overview of concepts like total pain, the WHO analgesic ladder for treating pain with opioids, and the importance of proper pain assessment and documentation. The key points are:
1) Total pain includes physical, psychosocial, emotional, and spiritual suffering experienced by cancer patients.
2) The WHO analgesic ladder recommends treating mild pain with non-opioids like paracetamol, moderate pain with weak opioids like codeine, and severe pain with strong opioids like morphine.
3) Proper pain assessment involves documenting pain scores, characteristics, causes, and impact on function to effectively guide pain treatment decisions.
The document discusses pain in preterm and term neonates. It states that the pain system is intact and functional in both populations. Behavioral responses like facial expressions and cry characteristics can indicate pain. The development of sensory receptors and connections allow pain to be processed by 20 weeks gestation. While neonatal pain may not be recalled, it can have long term impacts on brain development and later health and behavior. Effective pain assessment and management are important to provide neonatal patients.
This document provides an overview of acute pain management in children. It discusses the difficulties in assessing and treating pain in children, as well as the physiological and behavioral effects of acute pain. General principles for managing acute pain in children include anticipating and preventing pain, adequately assessing pain using age-appropriate tools, using a multi-modal approach including pharmacological and non-pharmacological therapies, involving parents, and using non-noxious routes of medication administration when possible. Specific pharmacological therapies for acute pain in children such as acetaminophen, NSAIDs, opioids, and local anesthetics are also reviewed.
This document discusses pain management in pediatric patients. It begins by presenting two case studies and then outlines objectives to understand different types of pain, how to initiate pain medications, and how to assess pain and modify treatment strategies. It describes nociceptive and neuropathic pain. It emphasizes the need to constantly re-assess pain plans, outlines tools for assessing pain in infants and verbal children, and provides guidance on both non-pharmacologic and pharmacologic pain management strategies and medications. Key takeaways include the importance of using an age-appropriate assessment tool, considering around-the-clock regimens, continually re-assessing pain and treatment plans, and guidelines for when to call the attending or transfer to a higher level
Dr. Fatma Al-Dammas is an anesthesiology professor and director of the anesthesia and acute/chronic pain management programs. She specializes in managing pain, which requires a multidisciplinary team approach. The goals of pain treatment are to improve quality of life, facilitate recovery, reduce morbidity, and allow for early hospital discharge. Pain management involves both pharmacological and non-pharmacological approaches, including the WHO pain ladder and various methods of drug delivery like epidural analgesia. Epidural analgesia provides effective post-operative pain relief, improves pulmonary function, and enables earlier ambulation.
The document discusses neonatal pain, including that babies can feel and react to pain, validated scales exist to measure neonatal pain, and developmental aspects of pain perception in newborns. It also outlines non-pharmacological and pharmacological approaches to treating pain in newborns, emphasizing the need for comprehensive pain management strategies that minimize unnecessary pain in neonates.
Pain is a distressing feeling often caused by intense or damaging stimuli. The International Association for the Study of Pain's widely used definition defines pain as "an unpleasant sensory and emotional experience associated with actual or potential tissue damage, or described in terms of such damage"
NURSE
EDUCATION
MANAGEMENT
NURSING CARE
NURSING ASSESSMENT
PLANNING
At the end of the session he students will be able to
Explain the activities of health care agencies
List out the types of health care agencies.
Classify the types of service
INTERVENTION
OBJECTIVES
LEARNING
IMPLEMENTATION
EVALUATION
RATIONALE
At the end of this session the leaner should be able to,
define pain.
classify pain.
describe mechanism of pain.
perform pain assessment.
detail the nursing interventions.
Development of manpower resources
Provision for safe water and food supply
Increasing the literacy rate
Reducing the levels of poverty
Chronic pain management involves comprehensive evaluation and treatment of pain. The IASP defines chronic pain as pain persisting beyond normal tissue healing time, usually 3 months. It impacts function and well-being. Treatment includes pharmacotherapy like opioids, nonopioids, and adjuvant analgesics. Opioids require careful patient selection, dosing, monitoring, and side effect management. Adjuvant analgesics like anticonvulsants and antidepressants are effective for neuropathic pain. A multimodal approach balances analgesia and side effects for optimal chronic pain treatment.
SpAn harus memberi waktu untuk pengelolaan nyeri
SpAn harus mampu mengelola nyeri dengan memilih cara yang paling aman, paling efektif dan paling ekonomis
Berperan aktif pada acute pain
Berperan, minimal partisipatif, dalam chronic pain
Berperan utama pada interventional pain management
Similar to PAIN MANAGEMENT AND DRUG DILUTION PPT .pptx (20)
Osvaldo Bernardo Muchanga-GASTROINTESTINAL INFECTIONS AND GASTRITIS-2024.pdfOsvaldo Bernardo Muchanga
GASTROINTESTINAL INFECTIONS AND GASTRITIS
Osvaldo Bernardo Muchanga
Gastrointestinal Infections
GASTROINTESTINAL INFECTIONS result from the ingestion of pathogens that cause infections at the level of this tract, generally being transmitted by food, water and hands contaminated by microorganisms such as E. coli, Salmonella, Shigella, Vibrio cholerae, Campylobacter, Staphylococcus, Rotavirus among others that are generally contained in feces, thus configuring a FECAL-ORAL type of transmission.
Among the factors that lead to the occurrence of gastrointestinal infections are the hygienic and sanitary deficiencies that characterize our markets and other places where raw or cooked food is sold, poor environmental sanitation in communities, deficiencies in water treatment (or in the process of its plumbing), risky hygienic-sanitary habits (not washing hands after major and/or minor needs), among others.
These are generally consequences (signs and symptoms) resulting from gastrointestinal infections: diarrhea, vomiting, fever and malaise, among others.
The treatment consists of replacing lost liquids and electrolytes (drinking drinking water and other recommended liquids, including consumption of juicy fruits such as papayas, apples, pears, among others that contain water in their composition).
To prevent this, it is necessary to promote health education, improve the hygienic-sanitary conditions of markets and communities in general as a way of promoting, preserving and prolonging PUBLIC HEALTH.
Gastritis and Gastric Health
Gastric Health is one of the most relevant concerns in human health, with gastrointestinal infections being among the main illnesses that affect humans.
Among gastric problems, we have GASTRITIS AND GASTRIC ULCERS as the main public health problems. Gastritis and gastric ulcers normally result from inflammation and corrosion of the walls of the stomach (gastric mucosa) and are generally associated (caused) by the bacterium Helicobacter pylor, which, according to the literature, this bacterium settles on these walls (of the stomach) and starts to release urease that ends up altering the normal pH of the stomach (acid), which leads to inflammation and corrosion of the mucous membranes and consequent gastritis or ulcers, respectively.
In addition to bacterial infections, gastritis and gastric ulcers are associated with several factors, with emphasis on prolonged fasting, chemical substances including drugs, alcohol, foods with strong seasonings including chilli, which ends up causing inflammation of the stomach walls and/or corrosion. of the same, resulting in the appearance of wounds and consequent gastritis or ulcers, respectively.
Among patients with gastritis and/or ulcers, one of the dilemmas is associated with the foods to consume in order to minimize the sensation of pain and discomfort.
PGx Analysis in VarSeq: A User’s PerspectiveGolden Helix
Since our release of the PGx capabilities in VarSeq, we’ve had a few months to gather some insights from various use cases. Some users approach PGx workflows by means of array genotyping or what seems to be a growing trend of adding the star allele calling to the existing NGS pipeline for whole genome data. Luckily, both approaches are supported with the VarSeq software platform. The genotyping method being used will also dictate what the scope of the tertiary analysis will be. For example, are your PGx reports a standalone pipeline or would your lab’s goal be to handle a dual-purpose workflow and report on PGx + Diagnostic findings.
The purpose of this webcast is to:
Discuss and demonstrate the approaches with array and NGS genotyping methods for star allele calling to prep for downstream analysis.
Following genotyping, explore alternative tertiary workflow concepts in VarSeq to handle PGx reporting.
Moreover, we will include insights users will need to consider when validating their PGx workflow for all possible star alleles and options you have for automating your PGx analysis for large number of samples. Please join us for a session dedicated to the application of star allele genotyping and subsequent PGx workflows in our VarSeq software.
Breast cancer: Post menopausal endocrine therapyDr. Sumit KUMAR
Breast cancer in postmenopausal women with hormone receptor-positive (HR+) status is a common and complex condition that necessitates a multifaceted approach to management. HR+ breast cancer means that the cancer cells grow in response to hormones such as estrogen and progesterone. This subtype is prevalent among postmenopausal women and typically exhibits a more indolent course compared to other forms of breast cancer, which allows for a variety of treatment options.
Diagnosis and Staging
The diagnosis of HR+ breast cancer begins with clinical evaluation, imaging, and biopsy. Imaging modalities such as mammography, ultrasound, and MRI help in assessing the extent of the disease. Histopathological examination and immunohistochemical staining of the biopsy sample confirm the diagnosis and hormone receptor status by identifying the presence of estrogen receptors (ER) and progesterone receptors (PR) on the tumor cells.
Staging involves determining the size of the tumor (T), the involvement of regional lymph nodes (N), and the presence of distant metastasis (M). The American Joint Committee on Cancer (AJCC) staging system is commonly used. Accurate staging is critical as it guides treatment decisions.
Treatment Options
Endocrine Therapy
Endocrine therapy is the cornerstone of treatment for HR+ breast cancer in postmenopausal women. The primary goal is to reduce the levels of estrogen or block its effects on cancer cells. Commonly used agents include:
Selective Estrogen Receptor Modulators (SERMs): Tamoxifen is a SERM that binds to estrogen receptors, blocking estrogen from stimulating breast cancer cells. It is effective but may have side effects such as increased risk of endometrial cancer and thromboembolic events.
Aromatase Inhibitors (AIs): These drugs, including anastrozole, letrozole, and exemestane, lower estrogen levels by inhibiting the aromatase enzyme, which converts androgens to estrogen in peripheral tissues. AIs are generally preferred in postmenopausal women due to their efficacy and safety profile compared to tamoxifen.
Selective Estrogen Receptor Downregulators (SERDs): Fulvestrant is a SERD that degrades estrogen receptors and is used in cases where resistance to other endocrine therapies develops.
Combination Therapies
Combining endocrine therapy with other treatments enhances efficacy. Examples include:
Endocrine Therapy with CDK4/6 Inhibitors: Palbociclib, ribociclib, and abemaciclib are CDK4/6 inhibitors that, when combined with endocrine therapy, significantly improve progression-free survival in advanced HR+ breast cancer.
Endocrine Therapy with mTOR Inhibitors: Everolimus, an mTOR inhibitor, can be added to endocrine therapy for patients who have developed resistance to aromatase inhibitors.
Chemotherapy
Chemotherapy is generally reserved for patients with high-risk features, such as large tumor size, high-grade histology, or extensive lymph node involvement. Regimens often include anthracyclines and taxanes.
Debunking Nutrition Myths: Separating Fact from Fiction"AlexandraDiaz101
In a world overflowing with diet trends and conflicting nutrition advice, it’s easy to get lost in misinformation. This article cuts through the noise to debunk common nutrition myths that may be sabotaging your health goals. From the truth about carbohydrates and fats to the real effects of sugar and artificial sweeteners, we break down what science actually says. Equip yourself with knowledge to make informed decisions about your diet, and learn how to navigate the complexities of modern nutrition with confidence. Say goodbye to food confusion and hello to a healthier you!
Computer in pharmaceutical research and development-Mpharm(Pharmaceutics)MuskanShingari
Statistics- Statistics is the science of collecting, organizing, presenting, analyzing and interpreting numerical data to assist in making more effective decisions.
A statistics is a measure which is used to estimate the population parameter
Parameters-It is used to describe the properties of an entire population.
Examples-Measures of central tendency Dispersion, Variance, Standard Deviation (SD), Absolute Error, Mean Absolute Error (MAE), Eigen Value
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“Psychiatry and the Humanities”: An Innovative Course at the University of Montreal Expanding the medical model to embrace the humanities. Link: https://www.psychiatrictimes.com/view/-psychiatry-and-the-humanities-an-innovative-course-at-the-university-of-montreal
4. LEARNING OBJECTIVES:
▸ At the end of this session we will be able to know the basics
of drug dilutions
▸ We will also be able to understand the basics of pain and its
management in pediatrics .
7. TEXT
PAIN ( FIFTH VITAL SIGN)
▸ International association for the study of pain (IASP)
“An unpleasant sensory and emotional experience associated
with actual and potential tissue damage”.
12. TEXT
CLASSIFICATION OF PAIN:
▸Acute pain ( subsides as tissue
is healed )
▸Chronic pain (>6months of
duration)
▸Malignant or non malignant
▸Based on anatomical location
15. TEXT
CHILD IN PAIN :
▸ Mostly under treated
▸ Painful experience for child and family
▸ Effects quality of life
▸ Increases rates of hospital admissions
16. TEXT
ASSESSMENT OF PAIN IN
PEDIATRICS
▸ Appropriate intervention
▸ Accurate evaluation
▸ Observational and behaviour
assessment tool
23. TEXT
PAIN SCORE 6-30
▸ Intervene when COMFORT-B scores of 17 or higher are
combined with VAS pain score of 4 or higher .
24.
25.
26.
27. PAIN MANAGEMENT
▸ Paediatricians often user treat
children’s pain
▸ When initiating pain medications ,
avoid combination products
▸ Constantly re-assess you pain pan
(Is it working ? . Any side effects??
35. TEXT
PAIN MEDICATIONS
▸ Acetaminophen :
▸ PO: 10-15mg/kg every 4-6 hours
▸ Ibuprofen:
▸ PO:05-10 mg /kg every 4-6 hours
(contraindicated in active GI
bleeding , hypersensitivity to NSAID
)
36. TEXT
KETOROLAC
▸ NSAID
▸ Available PO, IV, IM
▸ Potential opioid sparing effect
▸ Cannot be use for a long time
▸ No more than 24-72 hours in children less than 2 years
▸ No more than 5 days in children 2 and older
48. DRUG DILUTION
It is important for patient safety that you can :
▸ Accurately calculate an appropriate dose of drug for given
patient
▸ Prepare an accurate dilution of a given drug
49. SI UNITS
DEFINITION:
SI stands for system international and is
alternative name for the Matric system of
measurement
The main units are as following:
1. Weight (kg)
2. Volume (Litter)
3. Amount of substance (mole)
52. DILUTION
S
‣ ANYTHING REPRESENTED IN AN X:Y (E.G. 1:1000)
FASHION , IS X GRAMS OF DRUG ( OR SOLUTE )
DIVIDED BY Y MILLILITRES OF SOLUTIONS
‣ E.G. 1:1000 OF AN EPINEPHRINE SOLUTION
CONTAINS 1G OF EPINEPHRIN IN 1000 ML OF THE
SOLUTION
53.
54.
55. TEXT
REMEMBER THAT 1ML OF WATER WEIGHS 1G SO
…..
100% SOLUTION CONTAINS 100G IN 100ML
THIS IS THE SAME AS 1:1 SOLUTION