This study analyzes the relationship between innovative human resource management systems (IHRMS), information technology use, and firm performance in Catalan firms in Spain. The researchers surveyed 1,518 firms and used statistical analysis to group HRM practices and identify factors that determine adoption of IHRMS. They found that about one-third of firms have adopted innovative systems involving practices like flexible compensation, training, skills development, and management competencies. Firms using IHRMS tended to be more international, innovative, quality-focused, and have new work organizations and advanced IT. Internationalization, industry sector, group membership, IT use, innovation networks, supplier internationalization, decentralization, and efficiency increased the likelihood of IHRMS adoption.