1) Oral cancer screening is important because early detection can improve treatment outcomes, and visual screening has been shown to be effective and cost-effective for reducing oral cancer mortality.
2) Oral cancer screening should be performed by dental professionals on patients age 40 and over, tobacco and heavy alcohol users, those with HPV infection or family history of cancer. Screening involves visual examination of oral tissues and structures.
3) Dental clearance including examination and treatment is recommended before cancer therapy to prevent complications, and oral care during and after therapy can help manage issues like mucositis, xerostomia and osteoradionecrosis. Regular follow-up post-therapy is also important for preventive
Austin Pediatric Oncology is an open access, peer reviewed, scholarly journal dedicated to publish articles covering all areas of pediatric oncology.
The journal aims to promote research communications and provide a forum for doctors, researchers, physicians and healthcare professionals to find most recent advances in all areas of pediatric oncology. Austin Pediatric Oncology accepts original research articles, reviews, mini reviews, case reports and rapid communication covering all aspects of pediatric oncology.
Austin Pediatric Oncology strongly supports the scientific up gradation and fortification in related scientific research community by enhancing access to peer reviewed scientific literary works. Austin Publishing Group brings universally peer reviewed journals under one roof thereby promoting knowledge sharing, mutual promotion of multidisciplinary science.
Oral cancer is the most significant and growing concern worldwide. It ranks as 3rd in India and 8th
largest prevalent form of cancer in world. Oral cancer is often diagnosed, only after reached to an untreatable
stage. Early detection and prevention are the major objectives to control the oral cancer. Histopathology
analysis of biopsied lesion followed by visual examination is the current clinical procedure. This procedure is
invasive and requires a waiting period for the diagnostic results. Thus, there is a need to develop a non-invasive
screening device for oral cancer detection. Optical imaging has emerged as effective tool for detecting
malignant changes associated with oral cancer and also effective in assisting with the detection of oral mucosal
abnormalities. Hence, this paper focuses on development of non-invasive, real-time diagnostic tool based on
optical imaging technique in which involves - fluorescence emission and diffuse reflectance imaging modalities
for screening of oral cancer.
Minimum intervention dentistry is a concept based on a better understanding of the caries process and development of the carious process and the development of new diagnostic technologies and adhesives, bioactive restorative materials.
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and
offering a wide range of dental certified courses in different formats.for more details please visit
www.indiandentalacademy.com
Austin Pediatric Oncology is an open access, peer reviewed, scholarly journal dedicated to publish articles covering all areas of pediatric oncology.
The journal aims to promote research communications and provide a forum for doctors, researchers, physicians and healthcare professionals to find most recent advances in all areas of pediatric oncology. Austin Pediatric Oncology accepts original research articles, reviews, mini reviews, case reports and rapid communication covering all aspects of pediatric oncology.
Austin Pediatric Oncology strongly supports the scientific up gradation and fortification in related scientific research community by enhancing access to peer reviewed scientific literary works. Austin Publishing Group brings universally peer reviewed journals under one roof thereby promoting knowledge sharing, mutual promotion of multidisciplinary science.
Oral cancer is the most significant and growing concern worldwide. It ranks as 3rd in India and 8th
largest prevalent form of cancer in world. Oral cancer is often diagnosed, only after reached to an untreatable
stage. Early detection and prevention are the major objectives to control the oral cancer. Histopathology
analysis of biopsied lesion followed by visual examination is the current clinical procedure. This procedure is
invasive and requires a waiting period for the diagnostic results. Thus, there is a need to develop a non-invasive
screening device for oral cancer detection. Optical imaging has emerged as effective tool for detecting
malignant changes associated with oral cancer and also effective in assisting with the detection of oral mucosal
abnormalities. Hence, this paper focuses on development of non-invasive, real-time diagnostic tool based on
optical imaging technique in which involves - fluorescence emission and diffuse reflectance imaging modalities
for screening of oral cancer.
Minimum intervention dentistry is a concept based on a better understanding of the caries process and development of the carious process and the development of new diagnostic technologies and adhesives, bioactive restorative materials.
The Indian Dental Academy is the Leader in continuing dental education , training dentists in all aspects of dentistry and
offering a wide range of dental certified courses in different formats.for more details please visit
www.indiandentalacademy.com
Oral cancer awareness and knowledge in adults attending a dental hospital in ...Apollo Hospitals
Cancer, being one of the most common causes of death after
coronary heart diseases, causes nearly 7 million deaths each
year worldwide and according to WHO, presently, almost 25
million people are suffering from cancer, and by 2020 it is
projected that there may be 16 million new cancer cases and
ten million cancer deaths reported every year.1 In most
countries, one to ten cases per 1,00,000 people are diagnosed
with oral cancer every year. Though, it accounts for only two
percent of all cancers reported worldwide, it is the second
most common cancer in males and the fourth most common
cancer in females in South-Central Asia, accounting for seven
percent of the total cancers diagnosed in this region, ranking
among the three most common types of cancers reported in
the region.2 With 75,000e80,000 new cases of oral cancers
being reported every year, India has the highest prevalence of
oral cancer in the world. According GLOBOCON 2012 report,
oral cancer is a third most frequent cancer after breast and
cervix with an estimated 5-year prevalence rate of 6.6%.3 In
India, Northeast India including Assam accounts for more
than 40% of these cases.4 Oral cancer has a higher cure rate
when detected early and treated accordingly, but unfortu-
nately most oral cancers are diagnosed in advanced stages,
requiring aggressive treatment and associated morbidity,
resulting in higher mortality rates.
Indian Dental Academy: will be one of the most relevant and exciting training center with best faculty and flexible training programs for dental professionals who wish to advance in their dental practice,Offers certified courses in Dental implants,Orthodontics,Endodontics,Cosmetic Dentistry, Prosthetic Dentistry, Periodontics and General Dentistry.
Introduction to operative dentistry and Patient assessment.pptxridwana30
Introduction and the scope of operative dentistry with advancement of operative field. The examination procedure for assessing a patient for operative treatment and reaching a comprehensive treatment plan.
Oral cancer is one of the deadliest diseases affecting the human population, being one among the top ten causes of death occurring worldwide. Its high morbidity and mortality rate has not changed for the past 30 years, even after revolutions that are happening in its diagnosis and management. This alarming stage is a sequelae of its late diagnosis, with 80% of cases being diagnosed at late stages. A good number of screening techniques have been time tested for the predictive value in diagnosing oral cancer in an early premalignant stage. Although surgical biopsy is a gold standard for diagnosing, it needs professional services. Hence screening methods which are noninvasive and highly sensitive are accepted as an alternative of histopathology. Vital staining and vizilite are widely accepted methods among all the screening techniques and are widely used in a clinical setup.
Flu Vaccine Alert in Bangalore Karnatakaaddon Scans
As flu season approaches, health officials in Bangalore, Karnataka, are urging residents to get their flu vaccinations. The seasonal flu, while common, can lead to severe health complications, particularly for vulnerable populations such as young children, the elderly, and those with underlying health conditions.
Dr. Vidisha Kumari, a leading epidemiologist in Bangalore, emphasizes the importance of getting vaccinated. "The flu vaccine is our best defense against the influenza virus. It not only protects individuals but also helps prevent the spread of the virus in our communities," he says.
This year, the flu season is expected to coincide with a potential increase in other respiratory illnesses. The Karnataka Health Department has launched an awareness campaign highlighting the significance of flu vaccinations. They have set up multiple vaccination centers across Bangalore, making it convenient for residents to receive their shots.
To encourage widespread vaccination, the government is also collaborating with local schools, workplaces, and community centers to facilitate vaccination drives. Special attention is being given to ensuring that the vaccine is accessible to all, including marginalized communities who may have limited access to healthcare.
Residents are reminded that the flu vaccine is safe and effective. Common side effects are mild and may include soreness at the injection site, mild fever, or muscle aches. These side effects are generally short-lived and far less severe than the flu itself.
Healthcare providers are also stressing the importance of continuing COVID-19 precautions. Wearing masks, practicing good hand hygiene, and maintaining social distancing are still crucial, especially in crowded places.
Protect yourself and your loved ones by getting vaccinated. Together, we can help keep Bangalore healthy and safe this flu season. For more information on vaccination centers and schedules, residents can visit the Karnataka Health Department’s official website or follow their social media pages.
Stay informed, stay safe, and get your flu shot today!
Oral cancer awareness and knowledge in adults attending a dental hospital in ...Apollo Hospitals
Cancer, being one of the most common causes of death after
coronary heart diseases, causes nearly 7 million deaths each
year worldwide and according to WHO, presently, almost 25
million people are suffering from cancer, and by 2020 it is
projected that there may be 16 million new cancer cases and
ten million cancer deaths reported every year.1 In most
countries, one to ten cases per 1,00,000 people are diagnosed
with oral cancer every year. Though, it accounts for only two
percent of all cancers reported worldwide, it is the second
most common cancer in males and the fourth most common
cancer in females in South-Central Asia, accounting for seven
percent of the total cancers diagnosed in this region, ranking
among the three most common types of cancers reported in
the region.2 With 75,000e80,000 new cases of oral cancers
being reported every year, India has the highest prevalence of
oral cancer in the world. According GLOBOCON 2012 report,
oral cancer is a third most frequent cancer after breast and
cervix with an estimated 5-year prevalence rate of 6.6%.3 In
India, Northeast India including Assam accounts for more
than 40% of these cases.4 Oral cancer has a higher cure rate
when detected early and treated accordingly, but unfortu-
nately most oral cancers are diagnosed in advanced stages,
requiring aggressive treatment and associated morbidity,
resulting in higher mortality rates.
Indian Dental Academy: will be one of the most relevant and exciting training center with best faculty and flexible training programs for dental professionals who wish to advance in their dental practice,Offers certified courses in Dental implants,Orthodontics,Endodontics,Cosmetic Dentistry, Prosthetic Dentistry, Periodontics and General Dentistry.
Introduction to operative dentistry and Patient assessment.pptxridwana30
Introduction and the scope of operative dentistry with advancement of operative field. The examination procedure for assessing a patient for operative treatment and reaching a comprehensive treatment plan.
Oral cancer is one of the deadliest diseases affecting the human population, being one among the top ten causes of death occurring worldwide. Its high morbidity and mortality rate has not changed for the past 30 years, even after revolutions that are happening in its diagnosis and management. This alarming stage is a sequelae of its late diagnosis, with 80% of cases being diagnosed at late stages. A good number of screening techniques have been time tested for the predictive value in diagnosing oral cancer in an early premalignant stage. Although surgical biopsy is a gold standard for diagnosing, it needs professional services. Hence screening methods which are noninvasive and highly sensitive are accepted as an alternative of histopathology. Vital staining and vizilite are widely accepted methods among all the screening techniques and are widely used in a clinical setup.
Flu Vaccine Alert in Bangalore Karnatakaaddon Scans
As flu season approaches, health officials in Bangalore, Karnataka, are urging residents to get their flu vaccinations. The seasonal flu, while common, can lead to severe health complications, particularly for vulnerable populations such as young children, the elderly, and those with underlying health conditions.
Dr. Vidisha Kumari, a leading epidemiologist in Bangalore, emphasizes the importance of getting vaccinated. "The flu vaccine is our best defense against the influenza virus. It not only protects individuals but also helps prevent the spread of the virus in our communities," he says.
This year, the flu season is expected to coincide with a potential increase in other respiratory illnesses. The Karnataka Health Department has launched an awareness campaign highlighting the significance of flu vaccinations. They have set up multiple vaccination centers across Bangalore, making it convenient for residents to receive their shots.
To encourage widespread vaccination, the government is also collaborating with local schools, workplaces, and community centers to facilitate vaccination drives. Special attention is being given to ensuring that the vaccine is accessible to all, including marginalized communities who may have limited access to healthcare.
Residents are reminded that the flu vaccine is safe and effective. Common side effects are mild and may include soreness at the injection site, mild fever, or muscle aches. These side effects are generally short-lived and far less severe than the flu itself.
Healthcare providers are also stressing the importance of continuing COVID-19 precautions. Wearing masks, practicing good hand hygiene, and maintaining social distancing are still crucial, especially in crowded places.
Protect yourself and your loved ones by getting vaccinated. Together, we can help keep Bangalore healthy and safe this flu season. For more information on vaccination centers and schedules, residents can visit the Karnataka Health Department’s official website or follow their social media pages.
Stay informed, stay safe, and get your flu shot today!
ARTIFICIAL INTELLIGENCE IN HEALTHCARE.pdfAnujkumaranit
Artificial intelligence (AI) refers to the simulation of human intelligence processes by machines, especially computer systems. It encompasses tasks such as learning, reasoning, problem-solving, perception, and language understanding. AI technologies are revolutionizing various fields, from healthcare to finance, by enabling machines to perform tasks that typically require human intelligence.
- Video recording of this lecture in English language: https://youtu.be/lK81BzxMqdo
- Video recording of this lecture in Arabic language: https://youtu.be/Ve4P0COk9OI
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
- Link to NephroTube website: www.NephroTube.com
- Link to NephroTube social media accounts: https://nephrotube.blogspot.com/p/join-nephrotube-on-social-media.html
New Directions in Targeted Therapeutic Approaches for Older Adults With Mantl...i3 Health
i3 Health is pleased to make the speaker slides from this activity available for use as a non-accredited self-study or teaching resource.
This slide deck presented by Dr. Kami Maddocks, Professor-Clinical in the Division of Hematology and
Associate Division Director for Ambulatory Operations
The Ohio State University Comprehensive Cancer Center, will provide insight into new directions in targeted therapeutic approaches for older adults with mantle cell lymphoma.
STATEMENT OF NEED
Mantle cell lymphoma (MCL) is a rare, aggressive B-cell non-Hodgkin lymphoma (NHL) accounting for 5% to 7% of all lymphomas. Its prognosis ranges from indolent disease that does not require treatment for years to very aggressive disease, which is associated with poor survival (Silkenstedt et al, 2021). Typically, MCL is diagnosed at advanced stage and in older patients who cannot tolerate intensive therapy (NCCN, 2022). Although recent advances have slightly increased remission rates, recurrence and relapse remain very common, leading to a median overall survival between 3 and 6 years (LLS, 2021). Though there are several effective options, progress is still needed towards establishing an accepted frontline approach for MCL (Castellino et al, 2022). Treatment selection and management of MCL are complicated by the heterogeneity of prognosis, advanced age and comorbidities of patients, and lack of an established standard approach for treatment, making it vital that clinicians be familiar with the latest research and advances in this area. In this activity chaired by Michael Wang, MD, Professor in the Department of Lymphoma & Myeloma at MD Anderson Cancer Center, expert faculty will discuss prognostic factors informing treatment, the promising results of recent trials in new therapeutic approaches, and the implications of treatment resistance in therapeutic selection for MCL.
Target Audience
Hematology/oncology fellows, attending faculty, and other health care professionals involved in the treatment of patients with mantle cell lymphoma (MCL).
Learning Objectives
1.) Identify clinical and biological prognostic factors that can guide treatment decision making for older adults with MCL
2.) Evaluate emerging data on targeted therapeutic approaches for treatment-naive and relapsed/refractory MCL and their applicability to older adults
3.) Assess mechanisms of resistance to targeted therapies for MCL and their implications for treatment selection
263778731218 Abortion Clinic /Pills In Harare ,sisternakatoto
263778731218 Abortion Clinic /Pills In Harare ,ABORTION WOMEN’S CLINIC +27730423979 IN women clinic we believe that every woman should be able to make choices in her pregnancy. Our job is to provide compassionate care, safety,affordable and confidential services. That’s why we have won the trust from all generations of women all over the world. we use non surgical method(Abortion pills) to terminate…Dr.LISA +27730423979women Clinic is committed to providing the highest quality of obstetrical and gynecological care to women of all ages. Our dedicated staff aim to treat each patient and her health concerns with compassion and respect.Our dedicated group ABORTION WOMEN’S CLINIC +27730423979 IN women clinic we believe that every woman should be able to make choices in her pregnancy. Our job is to provide compassionate care, safety,affordable and confidential services. That’s why we have won the trust from all generations of women all over the world. we use non surgical method(Abortion pills) to terminate…Dr.LISA +27730423979women Clinic is committed to providing the highest quality of obstetrical and gynecological care to women of all ages. Our dedicated staff aim to treat each patient and her health concerns with compassion and respect.Our dedicated group of receptionists, nurses, and physicians have worked together as a teamof receptionists, nurses, and physicians have worked together as a team wwww.lisywomensclinic.co.za/
Couples presenting to the infertility clinic- Do they really have infertility...Sujoy Dasgupta
Dr Sujoy Dasgupta presented the study on "Couples presenting to the infertility clinic- Do they really have infertility? – The unexplored stories of non-consummation" in the 13th Congress of the Asia Pacific Initiative on Reproduction (ASPIRE 2024) at Manila on 24 May, 2024.
Pulmonary Thromboembolism - etilogy, types, medical- Surgical and nursing man...VarunMahajani
Disruption of blood supply to lung alveoli due to blockage of one or more pulmonary blood vessels is called as Pulmonary thromboembolism. In this presentation we will discuss its causes, types and its management in depth.
Knee anatomy and clinical tests 2024.pdfvimalpl1234
This includes all relevant anatomy and clinical tests compiled from standard textbooks, Campbell,netter etc..It is comprehensive and best suited for orthopaedicians and orthopaedic residents.
Explore natural remedies for syphilis treatment in Singapore. Discover alternative therapies, herbal remedies, and lifestyle changes that may complement conventional treatments. Learn about holistic approaches to managing syphilis symptoms and supporting overall health.
Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
NVBDCP.pptx Nation vector borne disease control programSapna Thakur
NVBDCP was launched in 2003-2004 . Vector-Borne Disease: Disease that results from an infection transmitted to humans and other animals by blood-feeding arthropods, such as mosquitoes, ticks, and fleas. Examples of vector-borne diseases include Dengue fever, West Nile Virus, Lyme disease, and malaria.
New Drug Discovery and Development .....NEHA GUPTA
The "New Drug Discovery and Development" process involves the identification, design, testing, and manufacturing of novel pharmaceutical compounds with the aim of introducing new and improved treatments for various medical conditions. This comprehensive endeavor encompasses various stages, including target identification, preclinical studies, clinical trials, regulatory approval, and post-market surveillance. It involves multidisciplinary collaboration among scientists, researchers, clinicians, regulatory experts, and pharmaceutical companies to bring innovative therapies to market and address unmet medical needs.
Prix Galien International 2024 Forum ProgramLevi Shapiro
June 20, 2024, Prix Galien International and Jerusalem Ethics Forum in ROME. Detailed agenda including panels:
- ADVANCES IN CARDIOLOGY: A NEW PARADIGM IS COMING
- WOMEN’S HEALTH: FERTILITY PRESERVATION
- WHAT’S NEW IN THE TREATMENT OF INFECTIOUS,
ONCOLOGICAL AND INFLAMMATORY SKIN DISEASES?
- ARTIFICIAL INTELLIGENCE AND ETHICS
- GENE THERAPY
- BEYOND BORDERS: GLOBAL INITIATIVES FOR DEMOCRATIZING LIFE SCIENCE TECHNOLOGIES AND PROMOTING ACCESS TO HEALTHCARE
- ETHICAL CHALLENGES IN LIFE SCIENCES
- Prix Galien International Awards Ceremony
1. Oral Medicine and Radiology
THEME
MULTIDICIPLINARY APPROACH FOR SCREENING,
DIAGNOSIS AND MANAGEMENT OF ORAL
CANCER
Presented By:
Dr. Abhishek Gupta
Assistant Professor and Incharge
School of Dental Sciences, CMC
17/04/2023
TOPIC
ROLE OF ORAL MEDICINE IN ORAL CANCER
(SCREENING/DENTAL CLEARANCE)
3. Oral Medicine and Radiology
CONTENTS
A. TOBACCO CESSATION COUNSELING
• Why, Who and How….??
B. ORAL CANCER SCREENING
• Why?
• When/who requires?
• Who should do?
• How to do?
C. ORAL CARE BEFORE (DENTAL CLEARANCE), DURING AND AFTER ANTINEOPLASTIC
THERAPY
• Why
• What is done…
4. Oral Medicine and Radiology
Bruni L, Albero G, Serrano B, Mena M, Collado JJ, Gómez D, Muñoz J, Bosch FX, de Sanjosé S. ICO/IARC Information Centre on HPV and Cancer
(HPV Information Centre). Human Papillomavirus and Related Diseases in Nepal. Summary Report 10 March 2023.
*b Rates per 100,000 Men/Year
*c Rates per 100,000 Women/Year
Some Facts……
5. Oral Medicine and Radiology
INTEGRATED FRAMEWORK FOR ORAL CANCER PREVENTION
7. Oral Medicine and Radiology
WHY??
• > 66% of cases are related to tobacco.*,**
• > 33% of cases are related to Alcohol.***
*Conway D I, Brenner D R, McMahon A D, et al. Estimating and explaining the effect of education and income on head and neck cancer
risk: INHANCE consortium pooled analysis of 31 case-control studies from 27 countries. Int J Cancer 2015; 136: 1125-1139
**Rivera C. Essentials of oral cancer. Int J Exp Pathol 2015; 8: 11884-11894.
***Maasland D H E, van den Brandt P A, Kremer B, et al. Alcohol consumption, cigarette smoking and the risk of subtypes of head-neck
cancer: Results from the Netherlands Cohort Study. BMC Cancer; 14. Epub ahead of print 14 March 2014.
11. Oral Medicine and Radiology
WHY ORAL CANCER SCREENING?
• Early detection can improve the patient's chances of
successful treatment
• Visual screening of the oral cavity has been widely evaluated
for its feasibility, safety, acceptability, accuracy in detecting
oral potentially malignant lesions and oral cancer, and efficacy
and cost-effectiveness in reducing oral cancer mortality*
• The purpose of screening is not only to detect oral cancer at
early stage but also to detect and manage patients with
OPMDs who are at risk for developing cancer**
*Kharbanda OP, Ivaturi A, Priya H, Dorji G, Gupta S. Digital possibilities in the prevention and early detection of oral cancer in the WHO South-
East Asia Region. WHO South-East Asia J Public Health 2019;8:95-10
**Warnakulasuriya S, Kerr AR. Oral Cancer Screening: Past, Present, and Future. J Dent Res. 2021 Nov;100(12):1313-1320. doi:
10.1177/00220345211014795. Epub 2021 May 26. PMID: 34036828; PMCID: PMC8529297.
12. Oral Medicine and Radiology
WHEN/WHO REQUIRES ??
• Self examination
• Report any changes, such as white/red
patches, lumps or sores
Every Month
• 40+ Age Group
• Tobacco and/or heavy alcohol Consumers
• Human Papillomavirus (HPV)
• Family history of cancer
Yearly
• 20+ Age Group
Once in 3 years
13. Oral Medicine and Radiology
WHO SHOULD SCREEN?
• Self Examination
• By Health Professionals (Dentist)
15. Oral Medicine and Radiology
EXAMINATION BY HEALTH PROFESSIONALS
Dental community is the first line of defense in early detection of the oral
cancer
– “Opportunistic” cancer screenings
– Screen all the patients who visit their practices
– Responsibility
17. Oral Medicine and Radiology
Areas to be screened:
• Lymph nodes
• Lips and vestibule
• Buccal mucosa
• Gingivae
• Dorsal and ventral surfaces of the tongue
• Lateral borders of the tongue
• Hard and soft palate
• Oropharynx
Hook H. It's not just about the teeth: The importance of screening for oral cancer and raising awareness. BDJ Student. 2021;28(3):28–9. doi:
10.1038/s41406-021-0224-4. Epub 2021 Aug 31. PMCID: PMC8407134.
18. Oral Medicine and Radiology
CHAIR SIDE METHODS AND ADVANCEMENTS IN THE DIAGNOSIS OF
ORAL CANCER:
Types Examples
Clinical Methods • Vital tissue staining
Cytopathology Examination
• Exfoliative cytology
• Brush Cytology/ Oral CDx
Visualization Adjuncts Tissue Auto
fluorescence
• VELscope
• In Vivo Confocal Microscopy
• Chemiluminescence (Vizilite)
Photo diagnosis
• Auto fluorescence Spectroscopy
• Fluorescence Photography
Babu NA. chair side diagnostic aids in early detection of oral cancer For general dental practitioners. European Journal of Molecular & Clinical
Medicine. 2020 Dec 16;7(10):668-73.
19. Oral Medicine and Radiology
ORAL CARE BEFORE ANTINEOPLASTIC THERAPY
• Complete dental examination and evaluation:
- Clinical examination of all oral and dental structures and palpation
- x- ray examination of teeth and supporting bony structures of the maxilla
and mandible
- Surgical removal of any remaining root tips or alveolar hyperplasia
• Criteria for pre- radiotherapy extractions of teeth :
- Caries (nonrestorable )
- Active periapical disease (symptomatic teeth )
- Moderate to severe periodontal disease
- Lack of opposing teeth ,compromised hygiene
- Partial impaction or incomplete eruption.
- Extensive periapical lesions (if not chronic or well localized )
20. Oral Medicine and Radiology
ORAL CARE DURING ANTINEOPLASTIC THERAPY
1. Dental Prophylaxis
2. Extensive hygiene instructions - brush training and adequate home care
maintenance
3. Custom made flexible mouthgaurds are fabricated from dental casts
4. Use of fluorides
5. Various mucosal guards and stents can be constructed as requested by
radiotherapist
6. Candida infection
7. Use of saliva substitutes should be encouraged to lubricate dried mucosal tissues
and decrease the chance of traumatic ulceration
8. Patients should be advised soft diet and cautioned to avoid spicy, acidic or
mechanically irritating foods
9. Good oral hygiene and daily fluoride use must be reinforced
10. Trismus prevention exercises should be reviewed
11. Denture wearing should be discouraged
21. Oral Medicine and Radiology
ORAL CARE AFTER ANTINEOPLASTIC THERAPY
• Recall once or twice during the first month followed by 3-4 month recall schedule
• Goal is to prevent radiation caries and periodontal disease, decrease the risk of
development of osteoradionecrosis and manage some of the chronic side effects
such as xerostomia
1. Oral mucosa: examined for irritation or ulceration
2. Adherence to oral hygiene and fluoride protocol needs to be reinforced
3. The interarch distance should be measured
4. Encourage to continue jaw opening excercises and physiotherapy (prevent
trismus)
5. Check for calculus and areas of demineralization or caries
6. Gentle scaling and root planning and polishing can be performed
7. Carious lesions and areas of demineralization need to be treated immediately
8. Post radiation extractions must be performed with careful handling of soft
tissues, alveolectomies, primary wound closure and antibiotic coverage
9. High risk of developing osteoradionecrosis: hyperbaric oxygen pre/post
operatively
TOBACCO CESSATION COUNSELING
Why?
Who should do?
ORAL CANCER SCREENING
WHY?
WHEN/WHO REQUIRE?
WHO SHOULD DO?
HOW TO DO?
DENTAL CARE BEFORE(DENTAL CLEARANCE), DURING AND AFTER ANTINEOPLASTIC RADIATION THERAPY
WHY?
WHAT IS DONE?
FACE - Look for swellings you have not noticed before andinspect your skin. Turn your head from side to side, stretchingthe skin over the muscles making lumps easier to see.
2. NECK - Run your fingers under your jaw and feel either side ofyour neck. Are there any swellings?
3. LIPS - Pull your upper lip upwards and bottom lip downwards.
Look inside for any sores or changes in colour.
4. GUMS - Examine your gums feeling around the gum for
anything unusual.
5. CHEEKS - Open your mouth and pull your cheek away one side
at a time. Look for any red or white patches. Check for ulcers,
lumps or tenderness.
6. TONGUE - Gently pull out your tongue and examine one side
then the other. Look for swellings, ulcers or changes in colour.
Examine the underside of your tongue.