Presentation from OIS@ASCRS 2017 Barry Cheskin, Co-Founder, President & CEO

1. OIS @ ASCRS 2017, Los Angeles
Barry Cheskin, May 4, 2017

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The FluidVision® AIOL Advantage
PowerVision │ FluidVision® AIOL
First true shape changing, fluid-driven IOL
Mimics eye’s natural accommodative process
Creates a continuously variable monofocal
Designed for consistent, high image quality over entire range of powers

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FluidVision 20/20 Progress
PowerVision │ FluidVision® AIOL
Launch into Clinic
Design Verification and
Validation
Animal Study
Design Complete

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Mechanism of the FluidVision Lens
When the eye moves to its natural accommodated state,
the capsular bag squeezes a tiny amount of fluid from the
haptics at the periphery of the AIOL into the center
This inflates the lens, giving near vision
When the eye attempts to move to its disaccommodated state,
the capsular bag squeezes fluid the other way
This deflates the lens, giving far vision
PowerVision │ FluidVision® AIOL

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Excellent Clinical Outcomes with Prior Generation
PowerVision │ FluidVision® AIOL
Results presented by Louis D. “Skip” Nichamin, MD and Paul Roux, MD at ESCRS, Copenhagen, September 2016; image courtesy of Frik Potgieter, MD, Optimed Eye and Laser Clinic, Pretoria, SA

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Update on the FluidVision 20/20 Pilot Study
PowerVision │ FluidVision® AIOL
Just launched FluidVision 20/20 into the clinic
Six sites in South Africa enrolling patients
23 successful surgeries completed to date
Early results very promising
Straightforward surgical technique

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FluidVision 20/20 Implantation
PowerVision │ FluidVision® AIOL

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FluidVision 20/20: Excellent Image Quality over Range of Powers
PowerVision │ FluidVision® AIOL
Advanced
Multifocal
Design
FluidVision 20/20
Far Near
0.0 D +1.0 D +2.0 D +3.0 D
From PowerVision bench testing

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FluidVision 20/20: Early Data on Objective Accommodation
PowerVision │ FluidVision® AIOL
Objective accommodation amplitude with the FluidVision 20/20
2 example patients

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PowerVision Innovation Pipeline
PowerVision │ FluidVision® AIOL
3.5 mm
incision
FluidVision 20/20
3.2 mm
incision
Toric
Post implant
adjustment,
2.8 mm incision