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Res Inves Sports Med Copyright © Benjamin Tseng
Volume 2 - Issue - 1
Aging vs Brain Plasticity
On average, humans will develop and retain a steady number
of neural connections throughout lifespan. However, as we age
our overall number of neurons decreases; therefore, requiring
us to share aever-declining resource of neural connections [1].
It has been observed that these connections tend to realign or
redistribute as a means of both normal aging and brain pathology.
This rewiring of new neural pathway’s functions to provide
for new learning of common activities of daily living and other
important communication and motor skills, and has been observed
via positron emission tomography (PET) scans in acute practice
of verbal and motor tasks in normal adult brains [2]. In normal
adults, excitation in brain regions for new learning is observed in a
secondary network consisting of the prefrontal cortex and anterior
cingulate cortex as well as other areas specific to the task. This
secondary network of neural connections is dubbed the scaffolding
areas and is important for the learning of a new motor skill for all
ages.
Contemporary View of Compensatory Mechanisms in
Cognitive Aging
The Scaffolding Theory of Aging and Cognition (STAC) states
that as a compensatory mechanism neural excitability, seen as new
brain circuit pathways in the areas outside of the primary network,
will act to compensate the decrease in available neurons. This
may be due to a decrease in total brain volume, specifically white
matter, overall structural integrity as a function of age or pathology,
or decreased number of dopaminergic pathways [3]. STAC suggests
neural pathway activation changes may be permanent changes that
are a result of overused or underused areas of the brain, but the
scaffolding areas of the brain could be trained or reprogrammed
to be more efficient. Interventional training may help transfer the
execution of simple skills back to the default primary networks, or
optimize the scaffolding areas of the brain to function as proficiently
as the default. Upon revisiting their theory five years later, Park
and colleagues added the inclusion of “life-course factors” such
as experience, genetics and environmental influence that may be
variables that affect the early onset of the use scaffolding areas to
complete simple skills [4].
Although it is recognized that compensatory neural networks
assist with the computations performed by the primary or default
network,therequireduseofcompensatorynetworksinolderadults
has been observed to be less efficient than primary networks used
by young adults that do the same task. A few relevant questions
remain unanswered concerning this topic-What exactly causes
these neural adaptations? Are they entirely detrimental? And what
can be done to prevent any cognitive decline that may be associated
with these age-related adaptations? Currently, researchers aim to
detect if starting interventions at middle age or later adulthood
are beneficial to optimize the scaffolding effect on the secondary
networks to make them more efficient.
Known Contributing Factors on Cognitive Performance
Emergingevidencehasshownthataerobictrainingandstrength
training have positive effects on increasing cognitive function and
motor performance in older adults [5]. Life-long participation
in aerobic training has shown to attenuate the loss of regional
brain volume [6]. Conversely, older adults with limited mobility
exhibited accelerated accumulation of white matter abnormalities
Benjamin Tseng* and Colby Craddock
Department of Health and Kinesiology, The University of Texas at Tyler, USA
*Corresponding author: Benjamin Tseng, PhD, Laboratory of Brain Aging and Neuromotor Behavior, Department of Health and Kinesiology, The
University of Texas at Tyler, 3900 University Blvd, Tyler, TX 75799, USA
Submission: February 24, 2018; Published: February 27, 2018
Old Dog, New Tricks: Learning Novel Motor
Tasks May Enhance Brain Health in Older Adults
Editorial
96Copyright © All rights are reserved by Benjamin Tseng.
Abstract
Maintaining cognitive vitality remains challenging in our rapidly aging society. It has been well documented that as we age, even simple daily
tasks become challenging as it increasingly draws cognitive resources from neural pathways outside of the primary motor cortex. The purpose of
this statement is to explore the potential use of novel motor training as a countermeasure to alleviate cognitive declines in older adults.
Keywords: Motor control; Cognitive aging; Mild cognitive impairment
Research & Investigations in
Sports MedicineC CRIMSON PUBLISHERS
Wings to the Research
ISSN 2577-1914
Res Inves Sports Med Copyright © Benjamin Tseng
97
How to cite this article: Benjamin T, Colby C. Old Dog, New Tricks: Learning Novel Motor Tasks May Enhance Brain Health in Older Adults. Res Inves
Sports Med. 2(1). RISM.000526. 2018. DOI: 10.31031/RISM.2018.02.000526
Volume 2 - Issue - 1
over a 5-year period [7]. The reduction in white matter integrity
has been linked to cognitive instability and motor deficits [8]. The
performance of motor coordination has shown to require a higher
cognitive demand in older adults where neural excitability has
been observed to operate in both hemispheres of the motor cortex
[9], and better performance of physical tasks has been linked to
excitation within the primary hemisphere for a unilateral task
compared to those observed to involve both hemispheres [10].
Novel Gross Motor Training May Enhance Brian Health
in Older Adults
Previous studies have measured cognitive and motor function
for simple ipsilateral tasks and found that younger subjects
outperformed the older subjects by expressing more motor
coordination stability, while concurrently activating less brain
regions than the older subjects [11]. Interestingly, Berryman et al.
[5] observed that in some cases, gross movement motor training
yields similar beneficial effects on executive function as aerobic
training would confer. To date, very few investigations examined
if complex gross motor tasks would promote and enhance
performance in cognitive functions in older adults.
Tsengetal.[6]studiedagroupofolderadultsaged50-70(N=36)
undergoing an 8-week intervention consisted of Bilateral Object
Manipulation training (BOM) of 3-ball juggling and conventional
exercise training [12]. Physical function was evaluated by Range-
of-Motion (ROM), Simple and Choice Reaction Times (SRT & CRT),
functional reach, and Gait Velocity (GV). Tseng et al. [6] revealed
that 8 weeks of BOM training may promote better excitability,
reacting time, mobility, and dynamic balance in older adults. Their
finding shed light on the clinical implication of a potentially cost-
effective home-based therapeutic intervention in preserving daily-
living function in older adults. Of note, it appears to be critical that
when learning new motor skills to incorporate non-dominant hand
[13], and tasks that incorporates multi-limb coordination may offer
augmented benefits for older adults [14].
Promoting physical and cognitive health and maintaining
functional capacity of daily activities is imperative in our aging
society. Future research should 1) Aim to validate the physiologic
mechanisms involved in the training adaptations observed in the
current research, 2) Confirm the efficacy of novel motor learning in
preserving cognitive function in older adults, and finally 3) Explore
the potential therapeutic intervention using the BOM model in
clinical population such as mild cognitive impairment and early
stage dementia.
References
1.	 Stern Y (2002) What is cognitive reserve? Theory and research
application of the reserve concept. J Int Neuropsychol Soc 8(3): 448-460.
2.	 Petersen SE, van Mier H, Fiez JA, Raichle ME (1998) The effects of
practice on the functional anatomy of task performance. Proc Natl Acad
Sci USA 95(3): 853-860.
3.	 Park DC, Reuter-Lorenz P (2009) The adaptive brain: aging and
neurocognitive scaffolding. Annu Rev Psychol 60: 173-196.
4.	 Reuter-Lorenz PA, Park DC (2014) How does it STAC up? Revisiting the
scaffolding theory of aging and cognition. Neuropsychol Rev 24(3): 355-
370.
5.	 Berryman N, Bherer L, Nadeau S, Lauziere S, Lehr L, et al. (2014) Multiple
roads lead to Rome: combined high-intensity aerobic and strength
training vs. gross motor activities leads to equivalent improvement
in executive functions in a cohort of healthy older adults. Age (Dordr)
36(5): 9710.
6.	 Tseng BY, Uh J, Rossetti HC, Cullum CM, Diaz-Arrastia RF, et al. (2013)
Masters athletes exhibit larger regional brain volume and better
cognitive performance than sedentary older adults. J Magn Reson
Imaging 38(5): 1169- 1176.
7.	 Wolfson L, Wei X, Hall CB, Panzer V, Wakefield D, et al. (2005) Accrual
of MRI white matter abnormalities in elderly with normal and impaired
mobility. J Neurol Sci 232(1-2): 23-27.
8.	 Tseng BY, Cullum CM, Zhang R (2014) Older adults with amnestic mild
cognitive impairment exhibit exacerbated gait slowing under dual-task
challenges. Curr Alzheimer Res 11(5): 494-500.
9.	 Graziadio S, Nazarpour K, Gretenkord S, Jackson A, Eyre JA (2015)
Greater intermanual transfer in the elderly suggests age-related bilateral
motor cortex activation is compensatory. J Mot Behav 47(1): 47-55.
10.	Cherry BJ, Yamashiro M, Anderson E, Barrett C, Adamson MM, et al.
(2010) Exploring interhemispheric collaboration in older compared to
younger adults. Brain Cogn 72(2): 218-227.
11.	Heuninckx S, Debaere F, Wenderoth N, Verschueren S, Swinnen SP (2004)
Ipsilateral coordination deficits and central processing requirements
associated with coordination as a function of aging. J Gerontol B Psychol
Sci Soc Sci 59(5): P225-P232.
12.	Tseng B, West R, Craddock C, Clark A (2017) Novel gross motor skill
training improves flexibility, reaction time, and mobility in older adults -
A pilot study. J Bone Muscles Stud 2017: 9-12.
13.	Schaefer SY, Dibble LE, Duff K (2015) Efficacy and feasibility of functional
upper extremity task-specific training for older adults with and without
cognitive impairment. Neurorehabil Neural Repair 29(7): 636-644.
14.	Hoff M, Trapp S, Kaminski E, Sehm B, Steele CJ, et al. (2015) Switching
between hands in a serial reaction time task: a comparison between
young and old adults. Front Aging Neurosci 7: 176.
Res Inves Sports Med Copyright © Benjamin Tseng
98
How to cite this article: Benjamin T, Colby C. Old Dog, New Tricks: Learning Novel Motor Tasks May Enhance Brain Health in Older Adults. Res Inves
Sports Med. 2(1). RISM.000526. 2018. DOI: 10.31031/RISM.2018.02.000526
Volume 2 - Issue - 1
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Old Dog, New Tricks: Learning Novel Motor Tasks May Enhance Brain Health in Older Adults_ Crimson Publishers

  • 1. Res Inves Sports Med Copyright © Benjamin Tseng Volume 2 - Issue - 1 Aging vs Brain Plasticity On average, humans will develop and retain a steady number of neural connections throughout lifespan. However, as we age our overall number of neurons decreases; therefore, requiring us to share aever-declining resource of neural connections [1]. It has been observed that these connections tend to realign or redistribute as a means of both normal aging and brain pathology. This rewiring of new neural pathway’s functions to provide for new learning of common activities of daily living and other important communication and motor skills, and has been observed via positron emission tomography (PET) scans in acute practice of verbal and motor tasks in normal adult brains [2]. In normal adults, excitation in brain regions for new learning is observed in a secondary network consisting of the prefrontal cortex and anterior cingulate cortex as well as other areas specific to the task. This secondary network of neural connections is dubbed the scaffolding areas and is important for the learning of a new motor skill for all ages. Contemporary View of Compensatory Mechanisms in Cognitive Aging The Scaffolding Theory of Aging and Cognition (STAC) states that as a compensatory mechanism neural excitability, seen as new brain circuit pathways in the areas outside of the primary network, will act to compensate the decrease in available neurons. This may be due to a decrease in total brain volume, specifically white matter, overall structural integrity as a function of age or pathology, or decreased number of dopaminergic pathways [3]. STAC suggests neural pathway activation changes may be permanent changes that are a result of overused or underused areas of the brain, but the scaffolding areas of the brain could be trained or reprogrammed to be more efficient. Interventional training may help transfer the execution of simple skills back to the default primary networks, or optimize the scaffolding areas of the brain to function as proficiently as the default. Upon revisiting their theory five years later, Park and colleagues added the inclusion of “life-course factors” such as experience, genetics and environmental influence that may be variables that affect the early onset of the use scaffolding areas to complete simple skills [4]. Although it is recognized that compensatory neural networks assist with the computations performed by the primary or default network,therequireduseofcompensatorynetworksinolderadults has been observed to be less efficient than primary networks used by young adults that do the same task. A few relevant questions remain unanswered concerning this topic-What exactly causes these neural adaptations? Are they entirely detrimental? And what can be done to prevent any cognitive decline that may be associated with these age-related adaptations? Currently, researchers aim to detect if starting interventions at middle age or later adulthood are beneficial to optimize the scaffolding effect on the secondary networks to make them more efficient. Known Contributing Factors on Cognitive Performance Emergingevidencehasshownthataerobictrainingandstrength training have positive effects on increasing cognitive function and motor performance in older adults [5]. Life-long participation in aerobic training has shown to attenuate the loss of regional brain volume [6]. Conversely, older adults with limited mobility exhibited accelerated accumulation of white matter abnormalities Benjamin Tseng* and Colby Craddock Department of Health and Kinesiology, The University of Texas at Tyler, USA *Corresponding author: Benjamin Tseng, PhD, Laboratory of Brain Aging and Neuromotor Behavior, Department of Health and Kinesiology, The University of Texas at Tyler, 3900 University Blvd, Tyler, TX 75799, USA Submission: February 24, 2018; Published: February 27, 2018 Old Dog, New Tricks: Learning Novel Motor Tasks May Enhance Brain Health in Older Adults Editorial 96Copyright © All rights are reserved by Benjamin Tseng. Abstract Maintaining cognitive vitality remains challenging in our rapidly aging society. It has been well documented that as we age, even simple daily tasks become challenging as it increasingly draws cognitive resources from neural pathways outside of the primary motor cortex. The purpose of this statement is to explore the potential use of novel motor training as a countermeasure to alleviate cognitive declines in older adults. Keywords: Motor control; Cognitive aging; Mild cognitive impairment Research & Investigations in Sports MedicineC CRIMSON PUBLISHERS Wings to the Research ISSN 2577-1914
  • 2. Res Inves Sports Med Copyright © Benjamin Tseng 97 How to cite this article: Benjamin T, Colby C. Old Dog, New Tricks: Learning Novel Motor Tasks May Enhance Brain Health in Older Adults. Res Inves Sports Med. 2(1). RISM.000526. 2018. DOI: 10.31031/RISM.2018.02.000526 Volume 2 - Issue - 1 over a 5-year period [7]. The reduction in white matter integrity has been linked to cognitive instability and motor deficits [8]. The performance of motor coordination has shown to require a higher cognitive demand in older adults where neural excitability has been observed to operate in both hemispheres of the motor cortex [9], and better performance of physical tasks has been linked to excitation within the primary hemisphere for a unilateral task compared to those observed to involve both hemispheres [10]. Novel Gross Motor Training May Enhance Brian Health in Older Adults Previous studies have measured cognitive and motor function for simple ipsilateral tasks and found that younger subjects outperformed the older subjects by expressing more motor coordination stability, while concurrently activating less brain regions than the older subjects [11]. Interestingly, Berryman et al. [5] observed that in some cases, gross movement motor training yields similar beneficial effects on executive function as aerobic training would confer. To date, very few investigations examined if complex gross motor tasks would promote and enhance performance in cognitive functions in older adults. Tsengetal.[6]studiedagroupofolderadultsaged50-70(N=36) undergoing an 8-week intervention consisted of Bilateral Object Manipulation training (BOM) of 3-ball juggling and conventional exercise training [12]. Physical function was evaluated by Range- of-Motion (ROM), Simple and Choice Reaction Times (SRT & CRT), functional reach, and Gait Velocity (GV). Tseng et al. [6] revealed that 8 weeks of BOM training may promote better excitability, reacting time, mobility, and dynamic balance in older adults. Their finding shed light on the clinical implication of a potentially cost- effective home-based therapeutic intervention in preserving daily- living function in older adults. Of note, it appears to be critical that when learning new motor skills to incorporate non-dominant hand [13], and tasks that incorporates multi-limb coordination may offer augmented benefits for older adults [14]. Promoting physical and cognitive health and maintaining functional capacity of daily activities is imperative in our aging society. Future research should 1) Aim to validate the physiologic mechanisms involved in the training adaptations observed in the current research, 2) Confirm the efficacy of novel motor learning in preserving cognitive function in older adults, and finally 3) Explore the potential therapeutic intervention using the BOM model in clinical population such as mild cognitive impairment and early stage dementia. References 1. Stern Y (2002) What is cognitive reserve? Theory and research application of the reserve concept. J Int Neuropsychol Soc 8(3): 448-460. 2. Petersen SE, van Mier H, Fiez JA, Raichle ME (1998) The effects of practice on the functional anatomy of task performance. Proc Natl Acad Sci USA 95(3): 853-860. 3. Park DC, Reuter-Lorenz P (2009) The adaptive brain: aging and neurocognitive scaffolding. Annu Rev Psychol 60: 173-196. 4. Reuter-Lorenz PA, Park DC (2014) How does it STAC up? Revisiting the scaffolding theory of aging and cognition. Neuropsychol Rev 24(3): 355- 370. 5. Berryman N, Bherer L, Nadeau S, Lauziere S, Lehr L, et al. (2014) Multiple roads lead to Rome: combined high-intensity aerobic and strength training vs. gross motor activities leads to equivalent improvement in executive functions in a cohort of healthy older adults. Age (Dordr) 36(5): 9710. 6. Tseng BY, Uh J, Rossetti HC, Cullum CM, Diaz-Arrastia RF, et al. (2013) Masters athletes exhibit larger regional brain volume and better cognitive performance than sedentary older adults. J Magn Reson Imaging 38(5): 1169- 1176. 7. Wolfson L, Wei X, Hall CB, Panzer V, Wakefield D, et al. (2005) Accrual of MRI white matter abnormalities in elderly with normal and impaired mobility. J Neurol Sci 232(1-2): 23-27. 8. Tseng BY, Cullum CM, Zhang R (2014) Older adults with amnestic mild cognitive impairment exhibit exacerbated gait slowing under dual-task challenges. Curr Alzheimer Res 11(5): 494-500. 9. Graziadio S, Nazarpour K, Gretenkord S, Jackson A, Eyre JA (2015) Greater intermanual transfer in the elderly suggests age-related bilateral motor cortex activation is compensatory. J Mot Behav 47(1): 47-55. 10. Cherry BJ, Yamashiro M, Anderson E, Barrett C, Adamson MM, et al. (2010) Exploring interhemispheric collaboration in older compared to younger adults. Brain Cogn 72(2): 218-227. 11. Heuninckx S, Debaere F, Wenderoth N, Verschueren S, Swinnen SP (2004) Ipsilateral coordination deficits and central processing requirements associated with coordination as a function of aging. J Gerontol B Psychol Sci Soc Sci 59(5): P225-P232. 12. Tseng B, West R, Craddock C, Clark A (2017) Novel gross motor skill training improves flexibility, reaction time, and mobility in older adults - A pilot study. J Bone Muscles Stud 2017: 9-12. 13. Schaefer SY, Dibble LE, Duff K (2015) Efficacy and feasibility of functional upper extremity task-specific training for older adults with and without cognitive impairment. Neurorehabil Neural Repair 29(7): 636-644. 14. Hoff M, Trapp S, Kaminski E, Sehm B, Steele CJ, et al. (2015) Switching between hands in a serial reaction time task: a comparison between young and old adults. Front Aging Neurosci 7: 176.
  • 3. Res Inves Sports Med Copyright © Benjamin Tseng 98 How to cite this article: Benjamin T, Colby C. Old Dog, New Tricks: Learning Novel Motor Tasks May Enhance Brain Health in Older Adults. Res Inves Sports Med. 2(1). RISM.000526. 2018. DOI: 10.31031/RISM.2018.02.000526 Volume 2 - Issue - 1 Your subsequent submission with Crimson Publishers will attain the below benefits • High-level peer review and editorial services • Freely accessible online immediately upon publication • Authors retain the copyright to their work • Licensing it under a Creative Commons license • Visibility through different online platforms • Global attainment for your research • Article availability in different formats (Pdf, E-pub, Full Text) • Endless customer service • Reasonable Membership services • Reprints availability upon request • One step article tracking system For possible submissions Click Here Submit Article Creative Commons Attribution 4.0 International License