This document provides strategies for using Twitter for various business purposes, including customer relations, crisis management, corporate reputation management, event activation, product promotion and sales, issue advocacy, and internal communication. Specific examples are given for how companies like Comcast, JetBlue, Zappos, Dell, and the Red Cross have effectively used Twitter for customer service, crisis response, thought leadership, event coverage, deals/sales, and advocacy. The strategies recommend following others on Twitter to listen, regularly creating useful content, and engaging with your followers through responses and questions.