In John Steinbeck's 1937 novella 'Of Mice and Men', two drifters, George and his simple-minded friend Lennie, dream of a better life, but their hopes unravel after they start working on a ranch during the Great Depression. The story reflects the struggles of migrant workers in California, amid economic collapse and ecological disasters like the Dust Bowl, highlighting the disparity between the American Dream and harsh realities. Rooted in historical events, the novella illustrates the concept that even the best-laid plans can often go awry.