Imaging Of
Obstructive
Jaundice
Presented by:
Dr. Bahaa Ahmad
introduction
• Jaundice manifests as yellow discolouration of the skin,
mucous membranes and sclerae.
• It is a clinical sign of hyperbilirubinemia (>2.5 mg/dl).
• It has many causes which can be largely divided into two
types:
 non-obstructive, i.e. pre-hepatic and hepatic causes
 obstructive, i.e. post-hepatic causes
• Imaging has a major role in detecting the obstructive causes.
Causes of obstructive jaundice
• Make Effective Presentations
• Using Awesome Backgrounds
• Engage your Audience
• Capture Audience Attention
Causes of Obstructive Jaundice
• Intraluminal causes:
 Gall stones
 Tumor.
 Ascariasis & Schitosomiasis
• Mural causes:
 Malignant stricture-cholangiocarcinoma
 Benign stricture- Scelerosing cholangitis
• Extrinsic Causes:
 Ca Head of Pancreas
 Periampullary Carcinoma,
 Portal LN
 Cholodochal cyst
 Mirizi syndrom.
Imaging Modalities:
A. Direct study :
1. Plain abdomen radiography .
2. U/S.
3. C.T., MRI.
4. ERCP .
5. Direct contrast study : operative cholangiogrophy,
P.T.C and post-operative - T-tube cholangiography.
6. Indirect contrast study : oral cholangiography is
contra-indicated in obstructive jaundice. iv
cholandiography.
7. fine needle biopsy.
B. Indirect study Ba. meal I.V.P.
Plain Abdominal X-ray
 Usually of little value.
 It can visualise the pathology which causes the obstruction :
a. Stones  radio-opaque stone in G.B. or hartmann’s pouch :
b. Calcification 
Calcified bladder wall  porcelain G.B  potentially malignant
(consequent to chronic inflammatory change).
Calcification in the pancreas  Chronic pancreatitis.
c. Gas in biliary tree  gall stone ileus/ post ERCP or
sphenctrotomy.
d. Paralytic ileus  acute pancreatitis and acute cholecysitis.
e. Bone  erosion, 2ries,  malignancy.
Gall bladder stones
Porcelain Gall Bladder
Gas in Biliary Tree (aerobilia)
Gas in Biliary Tree (aerobilia)
Ultrasound
Value 
1. Demonstration of dilated ducts.
2. Level of the obstruction.
3. Nature of the obstructed segment.
4. Deposits and Ascites.
Ultrasound
a. Gall stones :
b. Chronic cholecystitis :
- Gall stones.
- Wall thickening > 4 mm.
- - Contracted G.B. with no lumen.
c. Bile duct stones : visualize the stone and the dilated
C.B.D > 9mm
d. Pancreatic lesions: Acute pancreatitis  Chronic
pancreatitis  Benign tumour pancreatic carcinoma.
Gall bladder stones
CBD stone & dilatation/ IHBRD
Sclerosing cholangitis
Pancreatic Mass
Kaltaskin tumor (Hilar cholangiocarcinoma)
C.T. in obstructive jaundice
1. It is of value in distinguishing between extra or intra-hepatic cholestasis.
2. Dilated bile ducts  lower attenuation  linear or circular structures which
don’t enhance with contrast.
3.Dilated CBD  dilated tubular structure in porta-hepatis or pancreatic head.
4. In acute pancreatitis.
5. In chronic pancreatitis.
6. In pancreatic carcinoma.
7. Lymph node in the porta-hepatis  can be diagnosed early by C.T.
CT in biliary Obstruction
CT in biliary Obstruction
MRI & MRCP in obstructive jaundice
• MRI and MRCP are now routinely being used as the primary imaging modalities of the
hepatobiliary system .
• Excellent non-invasive and accurate imaging technique without the use of ionising radiation
and in many cases without the need for IV contrast.
• MRCP has been shown to have an overall 96–100% accuracy for the level of obstruction and
90% accuracy for the cause of obstruction .
• The main limitations of MRI:
 patients with claustrophobia
 patients with pacemakers
 the limited ability to offer therapeutic intervention.
MRI & MRCP in obstructive jaundice
Normal MRCP Biliary obstruction
MRI & MRCP in obstructive jaundice
MRI & MRCP in obstructive jaundice
Distal obstruction Sclerosing cholangitis
ERCP
Value:
• visualize both the biliary and pancreatic duct systems.
• obstruction relieve by the removal of stones, sphincterotomy and placement of stents and
drains.
• The addition of cholangioscopy to the ERCP allows for biopsies and brushings within the ducts.
Limitations:
• limited capacity to image the biliary tree proximal to the site of obstruction.
• cannot be performed if altered anatomy prevents endoscopic access to the ampulla .
Complications:
• Pancreatitis
• Perforation,
Biliary Peritonitis, Sepsis,
• Hemorrhage
• Adverse Effects From The Dye And The Drug Used To Relax The Duodenum
ERCP in obstructive jaundice
ERCP in obstructive jaundice
ERCP in obstructive jaundice
Percutaneous Transhepatic Cholangiopancreatography (PTC)
Value:
• useful for lesions proximal to the common hepatic duct.
• Biliary obstruction relief.
Limitations:
• The technique is not easy and requires considerable experience
Complications:
• Cholangitis.
• Peritonitis, Sepsis.
• Hemorrhage.
• Subphrenic abscess, and lung collapse
• Adverse Effects From The Dye .
Percutaneous Transhepatic Cholangiopancreatography (PTC)
Endoscopic US
Value:
• combines endoscopy and US to provide remarkably detailed images of
the pancreas and biliary tree.
• overcomes the limitation of evaluation of distal CBD by transabdominal
sonography.
• It is very accurate in diagnosing CBD calculi.
• It also picks up small resectable pancreatobilary mass with high
sensitivity (93-100%).
• allows diagnostic tissue sampling via EUS-guided fine-needle aspiration
.
Limitations:
• lack of expertise, availability of echoendoscopes, need for conscious
sedation
Indirect studies (Ba. meal)
a. Tumour in the pancreatic body and head may cause obstruction in the
pyloric antrum  duodenal loop  extrinsic invasion or compression.
b. cancer head---- Widening of the C. loop.
d. f. Lymphoma of the stomach  LN at portahepatis  Jaundice.
THANK
YOU

obst-jundice-medical learning exams.pptx

  • 1.
  • 2.
    introduction • Jaundice manifestsas yellow discolouration of the skin, mucous membranes and sclerae. • It is a clinical sign of hyperbilirubinemia (>2.5 mg/dl). • It has many causes which can be largely divided into two types:  non-obstructive, i.e. pre-hepatic and hepatic causes  obstructive, i.e. post-hepatic causes • Imaging has a major role in detecting the obstructive causes.
  • 3.
    Causes of obstructivejaundice • Make Effective Presentations • Using Awesome Backgrounds • Engage your Audience • Capture Audience Attention
  • 4.
    Causes of ObstructiveJaundice • Intraluminal causes:  Gall stones  Tumor.  Ascariasis & Schitosomiasis • Mural causes:  Malignant stricture-cholangiocarcinoma  Benign stricture- Scelerosing cholangitis • Extrinsic Causes:  Ca Head of Pancreas  Periampullary Carcinoma,  Portal LN  Cholodochal cyst  Mirizi syndrom.
  • 5.
    Imaging Modalities: A. Directstudy : 1. Plain abdomen radiography . 2. U/S. 3. C.T., MRI. 4. ERCP . 5. Direct contrast study : operative cholangiogrophy, P.T.C and post-operative - T-tube cholangiography. 6. Indirect contrast study : oral cholangiography is contra-indicated in obstructive jaundice. iv cholandiography. 7. fine needle biopsy. B. Indirect study Ba. meal I.V.P.
  • 6.
    Plain Abdominal X-ray Usually of little value.  It can visualise the pathology which causes the obstruction : a. Stones  radio-opaque stone in G.B. or hartmann’s pouch : b. Calcification  Calcified bladder wall  porcelain G.B  potentially malignant (consequent to chronic inflammatory change). Calcification in the pancreas  Chronic pancreatitis. c. Gas in biliary tree  gall stone ileus/ post ERCP or sphenctrotomy. d. Paralytic ileus  acute pancreatitis and acute cholecysitis. e. Bone  erosion, 2ries,  malignancy.
  • 7.
  • 8.
  • 9.
    Gas in BiliaryTree (aerobilia)
  • 10.
    Gas in BiliaryTree (aerobilia)
  • 11.
    Ultrasound Value  1. Demonstrationof dilated ducts. 2. Level of the obstruction. 3. Nature of the obstructed segment. 4. Deposits and Ascites.
  • 12.
    Ultrasound a. Gall stones: b. Chronic cholecystitis : - Gall stones. - Wall thickening > 4 mm. - - Contracted G.B. with no lumen. c. Bile duct stones : visualize the stone and the dilated C.B.D > 9mm d. Pancreatic lesions: Acute pancreatitis  Chronic pancreatitis  Benign tumour pancreatic carcinoma.
  • 13.
  • 14.
    CBD stone &dilatation/ IHBRD
  • 15.
  • 16.
  • 17.
    Kaltaskin tumor (Hilarcholangiocarcinoma)
  • 18.
    C.T. in obstructivejaundice 1. It is of value in distinguishing between extra or intra-hepatic cholestasis. 2. Dilated bile ducts  lower attenuation  linear or circular structures which don’t enhance with contrast. 3.Dilated CBD  dilated tubular structure in porta-hepatis or pancreatic head. 4. In acute pancreatitis. 5. In chronic pancreatitis. 6. In pancreatic carcinoma. 7. Lymph node in the porta-hepatis  can be diagnosed early by C.T.
  • 19.
    CT in biliaryObstruction
  • 20.
    CT in biliaryObstruction
  • 21.
    MRI & MRCPin obstructive jaundice • MRI and MRCP are now routinely being used as the primary imaging modalities of the hepatobiliary system . • Excellent non-invasive and accurate imaging technique without the use of ionising radiation and in many cases without the need for IV contrast. • MRCP has been shown to have an overall 96–100% accuracy for the level of obstruction and 90% accuracy for the cause of obstruction . • The main limitations of MRI:  patients with claustrophobia  patients with pacemakers  the limited ability to offer therapeutic intervention.
  • 22.
    MRI & MRCPin obstructive jaundice Normal MRCP Biliary obstruction
  • 23.
    MRI & MRCPin obstructive jaundice
  • 24.
    MRI & MRCPin obstructive jaundice Distal obstruction Sclerosing cholangitis
  • 25.
    ERCP Value: • visualize boththe biliary and pancreatic duct systems. • obstruction relieve by the removal of stones, sphincterotomy and placement of stents and drains. • The addition of cholangioscopy to the ERCP allows for biopsies and brushings within the ducts. Limitations: • limited capacity to image the biliary tree proximal to the site of obstruction. • cannot be performed if altered anatomy prevents endoscopic access to the ampulla . Complications: • Pancreatitis • Perforation, Biliary Peritonitis, Sepsis, • Hemorrhage • Adverse Effects From The Dye And The Drug Used To Relax The Duodenum
  • 26.
  • 27.
  • 28.
  • 29.
    Percutaneous Transhepatic Cholangiopancreatography(PTC) Value: • useful for lesions proximal to the common hepatic duct. • Biliary obstruction relief. Limitations: • The technique is not easy and requires considerable experience Complications: • Cholangitis. • Peritonitis, Sepsis. • Hemorrhage. • Subphrenic abscess, and lung collapse • Adverse Effects From The Dye .
  • 30.
  • 31.
    Endoscopic US Value: • combinesendoscopy and US to provide remarkably detailed images of the pancreas and biliary tree. • overcomes the limitation of evaluation of distal CBD by transabdominal sonography. • It is very accurate in diagnosing CBD calculi. • It also picks up small resectable pancreatobilary mass with high sensitivity (93-100%). • allows diagnostic tissue sampling via EUS-guided fine-needle aspiration . Limitations: • lack of expertise, availability of echoendoscopes, need for conscious sedation
  • 32.
    Indirect studies (Ba.meal) a. Tumour in the pancreatic body and head may cause obstruction in the pyloric antrum  duodenal loop  extrinsic invasion or compression. b. cancer head---- Widening of the C. loop. d. f. Lymphoma of the stomach  LN at portahepatis  Jaundice.
  • 33.