This document provides information about osteoarthritis of the knee. It begins with an overview of osteoarthritis, noting that it affects 44-70% of people over age 55 and is more common in weight-bearing joints. Risk factors include age, obesity, injury, heredity, and other joint conditions. Symptoms include pain, stiffness, reduced mobility, and deformities like bowing of the legs. The pathophysiology involves wear and tear of cartilage over time. Treatment focuses on lifestyle modifications, exercises, braces, medications, injections, and surgery for advanced cases including joint replacement.