A set of notes, formulas, diagrams, etc. written during the lecture for a 400-level computer & information sciences course. It describes how DNA primers will behave during each step of the PCR (polymerase chain reaction) in a concise manner. Throughout the pages, the term "primer" is being used to refer to single strands of oligonucleotide material as opposed to the typical nucleotides: adenine, guanine, thymine and cytosine. Note that oligonucleotides may pair with more than one regular nucleotide! The state that the DNA strands are in and what is being noted takes place before any nucleotides pair together--in fact, it may not be possible for a double helix to form depending upon how the sequences of oligonucleotide values are laid out.