Non-medelian.ppt
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This document discusses several types of non-Mendelian inheritance patterns, including incomplete dominance, codominance, multiple alleles, polygenic traits, and sex-linked traits. In incomplete dominance, a new phenotype appears as a blend of the dominant and recessive phenotypes in heterozygotes, such as pink flowers from crossing red and white. Codominance occurs when both alleles are fully expressed in heterozygotes, like black and white feathers on checkered chickens. Multiple alleles exist for some traits, such as the three blood type alleles in humans that result in A, B, AB, and O blood types. Problems are provided as examples for readers to work through crosses demonstrating these inheritance patterns.
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Non-Mendelian genetics describes inheritance patterns that differ from simple Mendelian dominant and recessive traits. These include incomplete dominance where the heterozygote expresses a blend of both homozygotes, codominance where both alleles are fully expressed in the heterozygote, multiple alleles where there are more than two allele options, polygenic traits which are influenced by multiple genes, and sex-linked traits which are carried on the X chromosome. Examples are given for each type of non-Mendelian inheritance.
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When I was asked to give a companion lecture in support of ‘The Philosophy of Science’ (https://shorturl.at/4pUXz) I decided not to walk through the detail of the many methodologies in order of use. Instead, I chose to employ a long standing, and ongoing, scientific development as an exemplar. And so, I chose the ever evolving story of Thermodynamics as a scientific investigation at its best.
Conducted over a period of >200 years, Thermodynamics R&D, and application, benefitted from the highest levels of professionalism, collaboration, and technical thoroughness. New layers of application, methodology, and practice were made possible by the progressive advance of technology. In turn, this has seen measurement and modelling accuracy continually improved at a micro and macro level.
Perhaps most importantly, Thermodynamics rapidly became a primary tool in the advance of applied science/engineering/technology, spanning micro-tech, to aerospace and cosmology. I can think of no better a story to illustrate the breadth of scientific methodologies and applications at their best.
ESA/ACT Science Coffee: Diego Blas - Gravitational wave detection with orbita...
ESA/ACT Science Coffee: Diego Blas - Gravitational wave detection with orbita...Advanced-Concepts-Team
Presentation in the Science Coffee of the Advanced Concepts Team of the European Space Agency on the 07.06.2024.
Speaker: Diego Blas (IFAE/ICREA)
Title: Gravitational wave detection with orbital motion of Moon and artificial
Abstract:
In this talk I will describe some recent ideas to find gravitational waves from supermassive black holes or of primordial origin by studying their secular effect on the orbital motion of the Moon or satellites that are laser ranged.The cost of acquiring information by natural selection
This is a short talk that I gave at the Banff International Research Station workshop on Modeling and Theory in Population Biology. The idea is to try to understand how the burden of natural selection relates to the amount of information that selection puts into the genome.
It's based on the first part of this research paper:
The cost of information acquisition by natural selection
Ryan Seamus McGee, Olivia Kosterlitz, Artem Kaznatcheev, Benjamin Kerr, Carl T. Bergstrom
bioRxiv 2022.07.02.498577; doi: https://doi.org/10.1101/2022.07.02.498577
Remote Sensing and Computational, Evolutionary, Supercomputing, and Intellige...
Remote Sensing and Computational, Evolutionary, Supercomputing, and Intellige...University of Maribor
Slides from talk:
Aleš Zamuda: Remote Sensing and Computational, Evolutionary, Supercomputing, and Intelligent Systems.
11th International Conference on Electrical, Electronics and Computer Engineering (IcETRAN), Niš, 3-6 June 2024
Inter-Society Networking Panel GRSS/MTT-S/CIS Panel Session: Promoting Connection and Cooperation
https://www.etran.rs/2024/en/home-english/在线办理(salfor毕业证书)索尔福德大学毕业证毕业完成信一模一样
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The binding of cosmological structures by massless topological defects
Assuming spherical symmetry and weak field, it is shown that if one solves the Poisson equation or the Einstein field
equations sourced by a topological defect, i.e. a singularity of a very specific form, the result is a localized gravitational
field capable of driving flat rotation (i.e. Keplerian circular orbits at a constant speed for all radii) of test masses on a thin
spherical shell without any underlying mass. Moreover, a large-scale structure which exploits this solution by assembling
concentrically a number of such topological defects can establish a flat stellar or galactic rotation curve, and can also deflect
light in the same manner as an equipotential (isothermal) sphere. Thus, the need for dark matter or modified gravity theory is
mitigated, at least in part.
Direct Seeded Rice - Climate Smart Agriculture
Direct Seeded Rice - Climate Smart AgricultureInternational Food Policy Research Institute- South Asia Office
PPT on Direct Seeded Rice presented at the three-day 'Training and Validation Workshop on Modules of Climate Smart Agriculture (CSA) Technologies in South Asia' workshop on April 22, 2024.
Describing and Interpreting an Immersive Learning Case with the Immersion Cub...
Current descriptions of immersive learning cases are often difficult or impossible to compare. This is due to a myriad of different options on what details to include, which aspects are relevant, and on the descriptive approaches employed. Also, these aspects often combine very specific details with more general guidelines or indicate intents and rationales without clarifying their implementation. In this paper we provide a method to describe immersive learning cases that is structured to enable comparisons, yet flexible enough to allow researchers and practitioners to decide which aspects to include. This method leverages a taxonomy that classifies educational aspects at three levels (uses, practices, and strategies) and then utilizes two frameworks, the Immersive Learning Brain and the Immersion Cube, to enable a structured description and interpretation of immersive learning cases. The method is then demonstrated on a published immersive learning case on training for wind turbine maintenance using virtual reality. Applying the method results in a structured artifact, the Immersive Learning Case Sheet, that tags the case with its proximal uses, practices, and strategies, and refines the free text case description to ensure that matching details are included. This contribution is thus a case description method in support of future comparative research of immersive learning cases. We then discuss how the resulting description and interpretation can be leveraged to change immersion learning cases, by enriching them (considering low-effort changes or additions) or innovating (exploring more challenging avenues of transformation). The method holds significant promise to support better-grounded research in immersive learning.
Unlocking the mysteries of reproduction: Exploring fecundity and gonadosomati...
The pygmy halfbeak Dermogenys colletei, is known for its viviparous nature, this presents an intriguing case of relatively low fecundity, raising questions about potential compensatory reproductive strategies employed by this species. Our study delves into the examination of fecundity and the Gonadosomatic Index (GSI) in the Pygmy Halfbeak, D. colletei (Meisner, 2001), an intriguing viviparous fish indigenous to Sarawak, Borneo. We hypothesize that the Pygmy halfbeak, D. colletei, may exhibit unique reproductive adaptations to offset its low fecundity, thus enhancing its survival and fitness. To address this, we conducted a comprehensive study utilizing 28 mature female specimens of D. colletei, carefully measuring fecundity and GSI to shed light on the reproductive adaptations of this species. Our findings reveal that D. colletei indeed exhibits low fecundity, with a mean of 16.76 ± 2.01, and a mean GSI of 12.83 ± 1.27, providing crucial insights into the reproductive mechanisms at play in this species. These results underscore the existence of unique reproductive strategies in D. colletei, enabling its adaptation and persistence in Borneo's diverse aquatic ecosystems, and call for further ecological research to elucidate these mechanisms. This study lends to a better understanding of viviparous fish in Borneo and contributes to the broader field of aquatic ecology, enhancing our knowledge of species adaptations to unique ecological challenges.
Compexometric titration/Chelatorphy titration/chelating titration
Classification
Metal ion ion indicators
Masking and demasking reagents
Estimation of Magnisium sulphate
Calcium gluconate
Complexometric Titration/ chelatometry titration/chelating titration, introduction, Types-
1.Direct Titration
2.Back Titration
3.Replacement Titration
4.Indirect Titration
Masking agent, Demasking agents
formation of complex
comparition between masking and demasking agents,
Indicators/Metal ion indicators/ Metallochromic indicators/pM indicators,
Visual Technique,PM indicators (metallochromic), Indicators of pH, Redox Indicators
Instrumental Techniques-Photometry
Potentiometry
Miscellaneous methods.
Complex titration with EDTA.
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The use of Nauplii and metanauplii artemia in aquaculture (brine shrimp).pptx
The use of Nauplii and metanauplii artemia in aquaculture (brine shrimp).pptx
Immersive Learning That Works: Research Grounding and Paths Forward
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Sharlene Leurig - Enabling Onsite Water Use with Net Zero Water
Sharlene Leurig - Enabling Onsite Water Use with Net Zero Water
Applied Science: Thermodynamics, Laws & Methodology.pdf
Applied Science: Thermodynamics, Laws & Methodology.pdf
ESA/ACT Science Coffee: Diego Blas - Gravitational wave detection with orbita...
ESA/ACT Science Coffee: Diego Blas - Gravitational wave detection with orbita...
The cost of acquiring information by natural selection
The cost of acquiring information by natural selection
Remote Sensing and Computational, Evolutionary, Supercomputing, and Intellige...
Remote Sensing and Computational, Evolutionary, Supercomputing, and Intellige...
The binding of cosmological structures by massless topological defects
The binding of cosmological structures by massless topological defects
Describing and Interpreting an Immersive Learning Case with the Immersion Cub...
Describing and Interpreting an Immersive Learning Case with the Immersion Cub...
Unlocking the mysteries of reproduction: Exploring fecundity and gonadosomati...
Unlocking the mysteries of reproduction: Exploring fecundity and gonadosomati...
Compexometric titration/Chelatorphy titration/chelating titration
Compexometric titration/Chelatorphy titration/chelating titration
Non-medelian.ppt
- 2. Mendelian Genetics: Dominant & Recessive Review One allele is DOMINANT over the other and the dominant allele will totally mask the recessive allele genotype: PP phenotype: purple genotype: pp phenotype: white genotype: Pp phenotype: purple
- 3. Review Problem: Dominant & Recessive In pea plants, purple flowers (P) are dominant over white flowers (p). Show the cross between two heterozygous plants. - % - ratio - % - ratio GENOTYPES: PHENOTYPES:
- 4. It’s not always Dominant/Recessive! Non-Mendelian Inheritance Patterns Incomplete Dominance Codominance Multiple Alleles Polygenic Traits Sex-Linked Traits
- 5. Incomplete Dominance a new phenotype appears in the heterozygous condition as a BLEND of the dominant and recessive phenotypes. Ex - Dominant Red (RR) + Recessive White (rr) = Hybrid Pink (Rr) RR = red rr = white Rr = pink
- 6. Problem: Incomplete Dominance Show the cross between a red and a white flower. - % - ratio - % - ratio GENOTYPES: PHENOTYPES:
- 7. Problem: Incomplete Dominance Show the cross between a pink and a white flower. - % - ratio - % - ratio GENOTYPES: PHENOTYPES:
- 8. Codominance in the heterozygous condition, both alleles are expressed equally with NO blending! Represented by using two DIFFERENT capital letters. Example - Sickle Cell Anemia: All Normal Cells (NN) + All sickled cells (SS) = half normal/half sickle carrier (NS) NN = normal cells SS = sickle cells NS = some of each
- 9. Codominance Example: Checkered Chickens BB = all black feathers WW = all white feathers BW = both black & white feathers (speckled) Notice – NO GRAY! NO BLEND! Each feather is either black or white
- 10. Codominance Example: Rhodedendron R = allele for red flowers W = allele for white flowers Cross a homozygous red flower with a homozygous white flower.
- 11. Codominance Example: Roan cattle cattle can be red (RR – all red hairs) white (WW – all white hairs) roan (RW – red and white hairs together)
- 12. Problem: Codominance in Appaloosa Horses Gray horses (GG) are codominant to white horses (WW). The heterozygous horse (GW) is an Appaloosa (a white horse with gray spots). Cross a white horse with an appaloosa horse. Give the genotype and phenotype ratio and percent.
- 13. Problem: Codominance in Sickle Cell Show the cross between an individual with sickle-cell anemia and another who is a carrier but not sick. - % - ratio - % - ratio GENOTYPES: PHENOTYPES:
- 14. Multiple Alleles Sometimes there are more than two alleles present in the gene pool for a gene. Ex – blood type consists of two dominant and one recessive allele in humans Allele A (IA) and B (IB) are dominant over Allele O (i). (NOTE: You still only get TWO alleles!!! One from mom and one from dad)
- 15. Multiple Alleles: Rabbit Fur Colors Fur colors (determined by 4 alleles): full color (C), chinchilla (cch), Himalayan (ch), albino (c)
- 16. Multiple Alleles: Blood Types (A, B, AB, O) Rules for Blood Types: (geno = pheno) A and B are co-dominant (Both show) IAIA = type A IBIB = type B IAIB = type AB A and B are both dominant over O (Regular dom/rec) IAi = type A IBi = type B ii = type O
- 17. Multiple Alleles: Blood Types (A, B, AB, O)
- 18. Phenotype Possible Genotype(s) Allele (antigen) on RBC surface Can Donate Blood To Can Receive Blood From A IAi IAIA A A, AB A, O B IBi IBIB B B, AB B, O AB IAIB AB AB A, B, AB, O O ii O A, B, AB, O O
- 19. Problem: Multiple Alleles Show the cross between a mother who has type O blood and a father who has type AB blood. - list - list GENOTYPES: PHENOTYPES:
- 20. Problem: Multiple Alleles Show the cross between a mother who is heterozygous for type B blood and a father who is heterozygous for type A blood. -list -list GENOTYPES: PHENOTYPES: