National Institute of Health Stroke Scale is used to assess the severity in ischemic stroke. it is very useful for stroke physicians for treatment and follow-up.
Global Medical Cures™| STROKE SCALE
DISCLAIMER-
Global Medical Cures™ does not offer any medical advice, diagnosis, treatment or recommendations. Only your healthcare provider/physician can offer you information and recommendations for you to decide about your healthcare choices.
Angiography is a test that uses an injection of dye to visualize arteries on X-rays. It is commonly used to examine blood vessels when considering surgery or to locate tumors. Patients prepare by fasting and taking medications as directed. The procedure involves inserting a catheter into an artery and injecting dye while images are taken. There are some risks like allergic reactions or damage to blood vessels. The results provide clear images of arteries to help diagnose conditions.
A presentation that talks about the Human Nervous System, the cranial nerves and the Neuro Assessment required to check if the nervous system is functioning properly.
This document provides information about the National Institutes of Health Stroke Scale (NIHSS), including how to administer and score it. The NIHSS is an 11-item neurological examination used to evaluate stroke severity. It assesses different functional domains, with higher scores indicating more severe strokes. An increase of 2 points or more on serial NIHSS exams indicates stroke progression. NIHSS scores can help predict outcomes and guide treatment decisions. The presenter reviews the components and administration of the full NIHSS exam.
Emergency plan and initial injury evaluationGallagherC15
Patellar tendonitis/jumper's knee
- Initial treatment is conservative with rest, ice, NSAIDs, patellar taping, strengthening exercises.
- If conservative treatment fails after 6-8 weeks, consider corticosteroid injection.
- Surgery is rarely required and usually only considered after failed conservative treatment for more than 3-6 months.
The document discusses the nervous system and how to assess it. It describes the three parts of the nervous system and the five steps of a neurological assessment: history collection, physical exam, differential diagnosis, diagnostic evaluation, and management plan. The physical exam involves assessing consciousness, cranial nerves, motor skills, reflexes, and sensory functions. It provides details on how to test each cranial nerve and reflex. Diagnostic tests that can further evaluate the nervous system like CT, MRI, PET, and EEG are also outlined.
Global Medical Cures™| STROKE SCALE
DISCLAIMER-
Global Medical Cures™ does not offer any medical advice, diagnosis, treatment or recommendations. Only your healthcare provider/physician can offer you information and recommendations for you to decide about your healthcare choices.
Angiography is a test that uses an injection of dye to visualize arteries on X-rays. It is commonly used to examine blood vessels when considering surgery or to locate tumors. Patients prepare by fasting and taking medications as directed. The procedure involves inserting a catheter into an artery and injecting dye while images are taken. There are some risks like allergic reactions or damage to blood vessels. The results provide clear images of arteries to help diagnose conditions.
A presentation that talks about the Human Nervous System, the cranial nerves and the Neuro Assessment required to check if the nervous system is functioning properly.
This document provides information about the National Institutes of Health Stroke Scale (NIHSS), including how to administer and score it. The NIHSS is an 11-item neurological examination used to evaluate stroke severity. It assesses different functional domains, with higher scores indicating more severe strokes. An increase of 2 points or more on serial NIHSS exams indicates stroke progression. NIHSS scores can help predict outcomes and guide treatment decisions. The presenter reviews the components and administration of the full NIHSS exam.
Emergency plan and initial injury evaluationGallagherC15
Patellar tendonitis/jumper's knee
- Initial treatment is conservative with rest, ice, NSAIDs, patellar taping, strengthening exercises.
- If conservative treatment fails after 6-8 weeks, consider corticosteroid injection.
- Surgery is rarely required and usually only considered after failed conservative treatment for more than 3-6 months.
The document discusses the nervous system and how to assess it. It describes the three parts of the nervous system and the five steps of a neurological assessment: history collection, physical exam, differential diagnosis, diagnostic evaluation, and management plan. The physical exam involves assessing consciousness, cranial nerves, motor skills, reflexes, and sensory functions. It provides details on how to test each cranial nerve and reflex. Diagnostic tests that can further evaluate the nervous system like CT, MRI, PET, and EEG are also outlined.
This document provides information on patient selection criteria, candidate types, and contraindications for spinal cord stimulation (SCS). Good candidates tend to have neuropathic or complex regional pain syndrome. Psychological screening is important, and those with untreated disorders like depression are poor candidates. The document also summarizes SCS techniques, types of implant systems, lead types, and trial lead placement procedures.
Assignment of clinical neurology. topic cranial nervesAmbreen Sadaf
Cranial nerves emerge directly from the brain and brainstem, relaying sensory and motor information between the brain and head/neck regions. There are 12 cranial nerves, which were assessed using various tests of sensory function like smell, vision, and touch, and motor function like eye and facial muscle movement, swallowing, and tongue protrusion. Abnormalities in these tests can help localize lesions to specific cranial nerves.
1) ICU patients require pain management and sedation to reduce stress and trauma. Validated scales like the BPS, CPOT, and NCS-R can assess pain in critically ill adults unable to self-report.
2) Sedation monitoring with scales like the SAS or RASS is recommended to guide treatment. Light sedation is preferred over deep sedation when possible. The BIS monitor may help guide sedation during deep sedation or paralysis.
3) Daily sedation interruption can improve outcomes but is not advised for patients with intracranial hypertension due to risk of increased ICP. The benefits of neurological wake up tests are uncertain due to potential risks of inducing stress responses.
This document provides information on methods for examining central nervous system reflexes through superficial and deep tendon reflex tests. It describes the components and techniques for assessing several key reflexes, including:
- Superficial reflexes like the corneal, palatal, abdominal, plantar, and cremasteric reflexes.
- Deep tendon reflexes like the biceps, triceps, knee jerk/patellar, and ankle reflexes.
For each reflex, it outlines the involved spinal roots and nerves, normal responses, and potential causes for absence of the reflex. Performing a full reflex examination can help evaluate the integrity of the spinal cord and peripheral nervous system.
This document provides guidance on performing a neurological assessment. It defines a neurological exam and explains that it is used to evaluate a patient's brain function and motor response. The assessment includes checking the patient's level of consciousness using the Glasgow Coma Scale, pupillary response, limb movement, strength, and vital signs. It outlines how to perform each part of the exam and what to note for things like eye opening, best verbal response, motor response, and limb movement. The neurological observation form is used to record the assessment findings. Any changes in neurological status should be reported immediately to the physician.
This document provides guidance on performing a neurological exam, including assessment of level of consciousness, motor function, sensation, reflexes, and cranial nerves. It emphasizes the importance of establishing a baseline, monitoring for subtle changes, and comparing findings to prior exams. Performing a thorough yet focused neuro exam allows for early detection of deterioration, which is critical for stroke patients. Consistent documentation and communication between caregivers helps ensure any changes are properly identified and addressed.
Rivermead Assessment of Somatosensory Performancestanbridge
The Rivermead Assessment of Somatosensory Performance (RASP) is a standardized test used to assess somatosensory functioning through 7 subtests involving discrimination of sensations like touch, pressure, temperature, and proprioception. It is comprised of standardized instruments that comprehensively measure somatosensory functions across 10 body areas. The RASP provides reliable and quantifiable data to inform rehabilitation for patients with somatosensory impairments from conditions like stroke, MS, or head injuries.
The document provides guidance on performing a neurological examination, including inspection, assessment of tone, power/strength, reflexes, and coordination. It describes how to examine the upper limbs, testing muscle strength for different actions like shoulder abduction, arm flexion, and wrist flexion. Reflexes like biceps, triceps, and brachioradialis are also discussed. The document then provides similar guidance for examining the lower limbs, outlining techniques to assess tone and check for ankle clonus.
This document provides information about the American Spinal Injury Association (ASIA) scale for classifying spinal cord injuries. It outlines the 5 steps for determining the ASIA grade: 1) determine sensory levels, 2) determine motor levels, 3) determine the neurological level of injury, 4) determine if the injury is complete or incomplete, and 5) determine the ASIA Impairment Scale grade (A-E). A 30-year-old man who fell 8 feet and had no motor function or voluntary anal contraction below his inguinal region is presented as a case example to demonstrate how to apply the ASIA scale.
The document discusses the American Spinal Injury Association (ASIA) scale, which is used to document sensory and motor impairments following a spinal cord injury. The ASIA scale assesses motor and sensory function in different dermatomes and assigns a letter grade from A to E. It allows clinicians to categorize patients based on the completeness of their injury and guide appropriate nursing care, rehabilitation efforts, and prognosis. The document also describes the development of a computerized system to calculate ASIA scores in order to make the assessment more efficient and accurate.
manual muscle testing by K Adhi lakshmi vapms copvrkv2007
Manual muscle testing (MMT) involves grading the strength of individual muscles or muscle groups on a scale based on their ability to perform movements against gravity or resistance. Key aspects of MMT include positioning and stabilizing the patient, demonstrating the movement, applying the appropriate grade of resistance, and documenting the results objectively. MMT is useful for assessing muscle weakness from various neuromuscular and musculoskeletal conditions and monitoring the effectiveness of treatment over time. Contraindications include certain neurological or orthopedic injuries or diseases that could be exacerbated by strength testing.
Acute Stroke protocol of management .. Dina Ashraf (ZUHP team 2012-2013 )Dina Ashraf
This document discusses several cases involving patients presenting with neurological symptoms. It includes details on the patients' histories, presenting symptoms, vital signs, and test results. The document provides guidance on the assessment and management of these types of cases as a house officer, including taking a history, performing examinations, ordering tests, making treatment decisions, providing supportive care, and monitoring for complications. Key steps outlined are recognizing stroke symptoms, conducting assessments like the NIH stroke scale, obtaining imaging, considering thrombolysis, controlling risk factors, and managing increased intracranial pressure or seizures.
This document appears to be a medical record containing instructions for administering a stroke scale assessment. It includes:
1. Fields for patient identification information and exam details.
2. Instructions and scoring definitions for 13 assessment items covering level of consciousness, gaze, visual fields, facial palsy, limb strength, ataxia, and sensation. Each item is scored on a scale of 0 to 3 or 4, with higher numbers indicating more severe neurological deficits.
3. The assessment is to be administered by recording the patient's performance on each item in the order listed, without returning to change scores. Performance is compared to defined criteria to determine the appropriate score.
This document provides guidelines for assessing limb muscle strength in critically ill patients using the Medical Research Council (MRC) Scale. It describes evaluating a patient's level of cooperation, assessing muscle strength on a 0-5 scale against gravity for each major muscle group, and calculating a total MRC sum score. Proper patient positioning, standardized testing procedures, encouragement, and accounting for delays in muscle contraction are emphasized to obtain accurate strength measurements.
The document discusses the effectiveness of electromyography-triggered neuromuscular electrical stimulation (EMG-triggered NMES) for stroke rehabilitation. It summarizes several peer-reviewed studies that found EMG-triggered NMES improved motor function and capabilities for individuals more than 1 year post-stroke. The studies showed EMG-triggered NMES was more effective than regular therapy or electrical stimulation alone and improved strength, range of motion, flexibility and motor skills. The document also provides specifications and safety information for a NeuroMove device that provides EMG-triggered NMES therapy.
The document discusses the effectiveness of electromyography-triggered neuromuscular electrical stimulation (EMG-triggered NMES) for stroke rehabilitation. It summarizes several peer-reviewed studies that found EMG-triggered NMES improved motor function and capabilities for individuals more than 1 year post-stroke. The studies showed EMG-triggered NMES was more effective than regular therapy or electrical stimulation alone and improved strength, range of motion, flexibility and motor skills. The document also provides specifications and safety information for a NeuroMove device that provides EMG-triggered NMES therapy.
The document discusses the effectiveness of electromyography-triggered neuromuscular electrical stimulation (EMG-triggered NMES) for stroke rehabilitation. It summarizes several peer-reviewed studies that found EMG-triggered NMES improved motor function and capabilities for individuals more than 1 year post-stroke. The studies showed EMG-triggered NMES was more effective than regular therapy or electrical stimulation alone and improved strength, range of motion, flexibility and motor skills. The document also provides specifications and safety information for a NeuroMove device that provides EMG-triggered NMES therapy.
This document provides instructions for conducting anthropometric tests to measure resting heart rate, blood pressure, and body composition. It describes how to locate the brachial and carotid arteries to take pulse readings, lists heart rate ranges by age and fitness level, and outlines the proper procedure for administering a blood pressure test, including ensuring the client is relaxed, positioning of the cuff and stethoscope, and interpreting the systolic over diastolic results. The goals are to demonstrate competency in accurately measuring these health indicators and providing clients with appropriate feedback and advice.
This document provides instructions for conducting anthropometric tests to measure resting heart rate, blood pressure, and body composition. It outlines how to locate the brachial and carotid arteries to take pulse readings, and how to properly administer a blood pressure test using a stethoscope and sphygmomanometer. Guidelines are provided for interpreting results and identifying potential health risks based on readings. Students will partner up to practice conducting these assessments and analyzing the findings.
EEG Lecture 3: Artifacts and Benign EEG variantsmunnam37
This document discusses various types of artefacts and benign EEG variants that may appear on an EEG. It describes mechanical and biological artefacts such as eye movements, muscle activity, and environmental electrical interference. Several benign rhythmic activities are also outlined, including rhythmic temporal theta bursts seen in drowsiness, midline theta rhythms, and frontal arousal rhythms. Additionally, different types of epileptiform discharges that do not indicate epilepsy are explained, like 14-6 Hz positive bursts, small sharp spikes, 6 Hz spike and wave patterns, and wicket spikes. The document provides examples of each type with corresponding figures.
- The document discusses different normal EEG patterns seen in awake and sleep states.
- It describes the typical frequency bands of EEG waves such as delta, theta, alpha, and beta waves.
- Specific normal EEG patterns like alpha rhythm, beta rhythm, mu rhythm, lambda rhythm, vertex sharp waves, POSTS, sleep spindles, K complexes are explained along with their characteristics and figures.
- The different stages of sleep like drowsiness, light sleep, deep sleep and REM sleep are outlined along with expected EEG findings in each stage.
More Related Content
Similar to NIHSS in Stroke Severity: Why and How? presentation.pptx
This document provides information on patient selection criteria, candidate types, and contraindications for spinal cord stimulation (SCS). Good candidates tend to have neuropathic or complex regional pain syndrome. Psychological screening is important, and those with untreated disorders like depression are poor candidates. The document also summarizes SCS techniques, types of implant systems, lead types, and trial lead placement procedures.
Assignment of clinical neurology. topic cranial nervesAmbreen Sadaf
Cranial nerves emerge directly from the brain and brainstem, relaying sensory and motor information between the brain and head/neck regions. There are 12 cranial nerves, which were assessed using various tests of sensory function like smell, vision, and touch, and motor function like eye and facial muscle movement, swallowing, and tongue protrusion. Abnormalities in these tests can help localize lesions to specific cranial nerves.
1) ICU patients require pain management and sedation to reduce stress and trauma. Validated scales like the BPS, CPOT, and NCS-R can assess pain in critically ill adults unable to self-report.
2) Sedation monitoring with scales like the SAS or RASS is recommended to guide treatment. Light sedation is preferred over deep sedation when possible. The BIS monitor may help guide sedation during deep sedation or paralysis.
3) Daily sedation interruption can improve outcomes but is not advised for patients with intracranial hypertension due to risk of increased ICP. The benefits of neurological wake up tests are uncertain due to potential risks of inducing stress responses.
This document provides information on methods for examining central nervous system reflexes through superficial and deep tendon reflex tests. It describes the components and techniques for assessing several key reflexes, including:
- Superficial reflexes like the corneal, palatal, abdominal, plantar, and cremasteric reflexes.
- Deep tendon reflexes like the biceps, triceps, knee jerk/patellar, and ankle reflexes.
For each reflex, it outlines the involved spinal roots and nerves, normal responses, and potential causes for absence of the reflex. Performing a full reflex examination can help evaluate the integrity of the spinal cord and peripheral nervous system.
This document provides guidance on performing a neurological assessment. It defines a neurological exam and explains that it is used to evaluate a patient's brain function and motor response. The assessment includes checking the patient's level of consciousness using the Glasgow Coma Scale, pupillary response, limb movement, strength, and vital signs. It outlines how to perform each part of the exam and what to note for things like eye opening, best verbal response, motor response, and limb movement. The neurological observation form is used to record the assessment findings. Any changes in neurological status should be reported immediately to the physician.
This document provides guidance on performing a neurological exam, including assessment of level of consciousness, motor function, sensation, reflexes, and cranial nerves. It emphasizes the importance of establishing a baseline, monitoring for subtle changes, and comparing findings to prior exams. Performing a thorough yet focused neuro exam allows for early detection of deterioration, which is critical for stroke patients. Consistent documentation and communication between caregivers helps ensure any changes are properly identified and addressed.
Rivermead Assessment of Somatosensory Performancestanbridge
The Rivermead Assessment of Somatosensory Performance (RASP) is a standardized test used to assess somatosensory functioning through 7 subtests involving discrimination of sensations like touch, pressure, temperature, and proprioception. It is comprised of standardized instruments that comprehensively measure somatosensory functions across 10 body areas. The RASP provides reliable and quantifiable data to inform rehabilitation for patients with somatosensory impairments from conditions like stroke, MS, or head injuries.
The document provides guidance on performing a neurological examination, including inspection, assessment of tone, power/strength, reflexes, and coordination. It describes how to examine the upper limbs, testing muscle strength for different actions like shoulder abduction, arm flexion, and wrist flexion. Reflexes like biceps, triceps, and brachioradialis are also discussed. The document then provides similar guidance for examining the lower limbs, outlining techniques to assess tone and check for ankle clonus.
This document provides information about the American Spinal Injury Association (ASIA) scale for classifying spinal cord injuries. It outlines the 5 steps for determining the ASIA grade: 1) determine sensory levels, 2) determine motor levels, 3) determine the neurological level of injury, 4) determine if the injury is complete or incomplete, and 5) determine the ASIA Impairment Scale grade (A-E). A 30-year-old man who fell 8 feet and had no motor function or voluntary anal contraction below his inguinal region is presented as a case example to demonstrate how to apply the ASIA scale.
The document discusses the American Spinal Injury Association (ASIA) scale, which is used to document sensory and motor impairments following a spinal cord injury. The ASIA scale assesses motor and sensory function in different dermatomes and assigns a letter grade from A to E. It allows clinicians to categorize patients based on the completeness of their injury and guide appropriate nursing care, rehabilitation efforts, and prognosis. The document also describes the development of a computerized system to calculate ASIA scores in order to make the assessment more efficient and accurate.
manual muscle testing by K Adhi lakshmi vapms copvrkv2007
Manual muscle testing (MMT) involves grading the strength of individual muscles or muscle groups on a scale based on their ability to perform movements against gravity or resistance. Key aspects of MMT include positioning and stabilizing the patient, demonstrating the movement, applying the appropriate grade of resistance, and documenting the results objectively. MMT is useful for assessing muscle weakness from various neuromuscular and musculoskeletal conditions and monitoring the effectiveness of treatment over time. Contraindications include certain neurological or orthopedic injuries or diseases that could be exacerbated by strength testing.
Acute Stroke protocol of management .. Dina Ashraf (ZUHP team 2012-2013 )Dina Ashraf
This document discusses several cases involving patients presenting with neurological symptoms. It includes details on the patients' histories, presenting symptoms, vital signs, and test results. The document provides guidance on the assessment and management of these types of cases as a house officer, including taking a history, performing examinations, ordering tests, making treatment decisions, providing supportive care, and monitoring for complications. Key steps outlined are recognizing stroke symptoms, conducting assessments like the NIH stroke scale, obtaining imaging, considering thrombolysis, controlling risk factors, and managing increased intracranial pressure or seizures.
This document appears to be a medical record containing instructions for administering a stroke scale assessment. It includes:
1. Fields for patient identification information and exam details.
2. Instructions and scoring definitions for 13 assessment items covering level of consciousness, gaze, visual fields, facial palsy, limb strength, ataxia, and sensation. Each item is scored on a scale of 0 to 3 or 4, with higher numbers indicating more severe neurological deficits.
3. The assessment is to be administered by recording the patient's performance on each item in the order listed, without returning to change scores. Performance is compared to defined criteria to determine the appropriate score.
This document provides guidelines for assessing limb muscle strength in critically ill patients using the Medical Research Council (MRC) Scale. It describes evaluating a patient's level of cooperation, assessing muscle strength on a 0-5 scale against gravity for each major muscle group, and calculating a total MRC sum score. Proper patient positioning, standardized testing procedures, encouragement, and accounting for delays in muscle contraction are emphasized to obtain accurate strength measurements.
The document discusses the effectiveness of electromyography-triggered neuromuscular electrical stimulation (EMG-triggered NMES) for stroke rehabilitation. It summarizes several peer-reviewed studies that found EMG-triggered NMES improved motor function and capabilities for individuals more than 1 year post-stroke. The studies showed EMG-triggered NMES was more effective than regular therapy or electrical stimulation alone and improved strength, range of motion, flexibility and motor skills. The document also provides specifications and safety information for a NeuroMove device that provides EMG-triggered NMES therapy.
The document discusses the effectiveness of electromyography-triggered neuromuscular electrical stimulation (EMG-triggered NMES) for stroke rehabilitation. It summarizes several peer-reviewed studies that found EMG-triggered NMES improved motor function and capabilities for individuals more than 1 year post-stroke. The studies showed EMG-triggered NMES was more effective than regular therapy or electrical stimulation alone and improved strength, range of motion, flexibility and motor skills. The document also provides specifications and safety information for a NeuroMove device that provides EMG-triggered NMES therapy.
The document discusses the effectiveness of electromyography-triggered neuromuscular electrical stimulation (EMG-triggered NMES) for stroke rehabilitation. It summarizes several peer-reviewed studies that found EMG-triggered NMES improved motor function and capabilities for individuals more than 1 year post-stroke. The studies showed EMG-triggered NMES was more effective than regular therapy or electrical stimulation alone and improved strength, range of motion, flexibility and motor skills. The document also provides specifications and safety information for a NeuroMove device that provides EMG-triggered NMES therapy.
This document provides instructions for conducting anthropometric tests to measure resting heart rate, blood pressure, and body composition. It describes how to locate the brachial and carotid arteries to take pulse readings, lists heart rate ranges by age and fitness level, and outlines the proper procedure for administering a blood pressure test, including ensuring the client is relaxed, positioning of the cuff and stethoscope, and interpreting the systolic over diastolic results. The goals are to demonstrate competency in accurately measuring these health indicators and providing clients with appropriate feedback and advice.
This document provides instructions for conducting anthropometric tests to measure resting heart rate, blood pressure, and body composition. It outlines how to locate the brachial and carotid arteries to take pulse readings, and how to properly administer a blood pressure test using a stethoscope and sphygmomanometer. Guidelines are provided for interpreting results and identifying potential health risks based on readings. Students will partner up to practice conducting these assessments and analyzing the findings.
Similar to NIHSS in Stroke Severity: Why and How? presentation.pptx (20)
EEG Lecture 3: Artifacts and Benign EEG variantsmunnam37
This document discusses various types of artefacts and benign EEG variants that may appear on an EEG. It describes mechanical and biological artefacts such as eye movements, muscle activity, and environmental electrical interference. Several benign rhythmic activities are also outlined, including rhythmic temporal theta bursts seen in drowsiness, midline theta rhythms, and frontal arousal rhythms. Additionally, different types of epileptiform discharges that do not indicate epilepsy are explained, like 14-6 Hz positive bursts, small sharp spikes, 6 Hz spike and wave patterns, and wicket spikes. The document provides examples of each type with corresponding figures.
- The document discusses different normal EEG patterns seen in awake and sleep states.
- It describes the typical frequency bands of EEG waves such as delta, theta, alpha, and beta waves.
- Specific normal EEG patterns like alpha rhythm, beta rhythm, mu rhythm, lambda rhythm, vertex sharp waves, POSTS, sleep spindles, K complexes are explained along with their characteristics and figures.
- The different stages of sleep like drowsiness, light sleep, deep sleep and REM sleep are outlined along with expected EEG findings in each stage.
EEG records electrical activity of the brain through electrodes placed on the scalp. The 10-20 system is commonly used for electrode placement. EEG signals are amplified and filtered before being displayed. Activation procedures like photic stimulation and hyperventilation are used to provoke seizures. Sleep deprivation and induction can also increase the diagnostic yield of EEG by altering brain activity. The visual analysis of EEG considers factors like waveforms, distribution, and reactivity to diagnose abnormalities.
BLOOD SUPPLY of brain and spinal cord.pptxmunnam37
The document summarizes the blood supply of the brain and spinal cord. It discusses the major arteries including the internal carotid, vertebral, and basilar arteries. It describes the branches and territories supplied by the anterior, middle, and posterior cerebral arteries. It also discusses important anastomoses like the Circle of Willis. Various artery syndromes are summarized such as anterior cerebral artery occlusion presenting with contralateral leg weakness. Important veins are also mentioned along with clinical correlations of arterial occlusions.
Post-COVID19 depression is a mood disorder that affects many COVID19 survivors and can involve relatives and healthcare workers. It is diagnosed using DSM-5 criteria and symptoms usually start after infection and can last weeks to months. Factors like severe initial infection, previous psychiatric conditions, and social isolation increase risk. Investigations aim to exclude other medical causes, and treatment involves psychotherapy, antidepressants, and other therapies like ECT. Preventing post-COVID19 depression focuses on early COVID19 treatment, managing preexisting conditions, and providing social and financial support.
This document provides information about the brainstem, including its parts (midbrain, pons, and medulla), functions, internal structures, blood supply, and various clinical case scenarios involving lesions or syndromes associated with the brainstem. It describes key features of the midbrain, pons, and medulla such as their locations, surfaces, and structures. It also summarizes several important brainstem syndromes and lesions, outlining the sites and clinical signs involved. Diagrams are included to illustrate anatomical structures and lesions.
This document provides information about the cerebellum and cerebellar disorders. It discusses examination of ataxia, symptoms of cerebellar ataxia including limb ataxia, truncal ataxia, dysarthria, and visual symptoms. It also covers different types of cerebellar disorders like tumors, infections, metabolic disorders, and case scenarios of patients presenting with ataxia. Imaging findings are described that can help identify the cause of ataxia.
The document discusses cranial nerves III (oculomotor), IV (trochlear), and VI (abducens). It describes the anatomy and nuclei of each nerve, their paths through the brain and orbit, the muscles they innervate, and examples of clinical lesions that can occur. Cranial nerve III has motor functions including eye movement and parasympathetic innervation. Cranial nerve IV is the only crossed nerve and innervates the superior oblique muscle. Cranial nerve VI innervates the lateral rectus muscle and is responsible for eye abduction.
This document discusses various clinical aspects of meningitis including:
1. Developmental issues like meningocele and meningomyelocele. Infectious causes such as meningitis, subdural empyema, and epidural abscess. Traumatic causes like epidural and subdural hemorrhages.
2. Vascular disorders including subarachnoid hemorrhage, dural venous sinus thrombosis, and dural arteriovenous fistulas. Disorders of CSF pressure like low pressure from spontaneous intracranial hypotension or high pressure from hydrocephalus.
3. Tumors affecting the meninges like meningiomas and secondary deposits from other cancers.
This document provides an overview of the medulla oblongata. It begins with an introduction and outline. It then describes the gross appearance and internal structures of the medulla, including the pyramids, olives, and medial lemnisci. It discusses the blood supply, venous drainage, and functions of the medulla, which include respiration, cardiac and vasomotor centers, and reflex centers. The document concludes by covering diseases of the medulla such as genetic, developmental, vascular, degenerative, infectious, inflammatory, and neoplastic conditions.
The meninges are the three membranes - the dura mater, arachnoid mater, and pia mater - that cover and protect the brain and spinal cord. The dura mater is the outermost and toughest layer. It is composed of an outer fibrous layer and inner meningeal layer. It contains folds like the falx cerebri and tentorium cerebelli. The arachnoid mater lies interior to the dura mater and is separated from it by the subdural space. Between the arachnoid mater and pia mater is the subarachnoid space, which contains cerebrospinal fluid. The pia mater is the innermost layer and closely adher
This document discusses anti-arrhythmic drugs and updates. It begins by defining arrhythmias and explaining why they should be treated. It then discusses factors that can precipitate arrhythmias and classifications of arrhythmias based on origin. The document focuses on the Vaughn Williams classification of anti-arrhythmic drugs into classes I-IV based on their mechanisms of action and effects on ion channels. Several examples of drugs from each class are described in detail including their indications, mechanisms of action, dosages, and adverse effects.
The thalamus is divided into anterior, medial, and lateral parts by the internal medullary lamina. The lateral part contains dorsal and ventral tiers of nuclei that relay sensory and motor information between the brainstem and cortex. The thalamus plays key roles in sensory relay, motor control, emotion/memory, and vegetative functions by transmitting information between different brain regions. Lesions of the ventral posteromedial and ventral posterolateral nuclei can cause loss of sensation on the opposite side of the body.
Are you looking for a long-lasting solution to your missing tooth?
Dental implants are the most common type of method for replacing the missing tooth. Unlike dentures or bridges, implants are surgically placed in the jawbone. In layman’s terms, a dental implant is similar to the natural root of the tooth. It offers a stable foundation for the artificial tooth giving it the look, feel, and function similar to the natural tooth.
Breast cancer: Post menopausal endocrine therapyDr. Sumit KUMAR
Breast cancer in postmenopausal women with hormone receptor-positive (HR+) status is a common and complex condition that necessitates a multifaceted approach to management. HR+ breast cancer means that the cancer cells grow in response to hormones such as estrogen and progesterone. This subtype is prevalent among postmenopausal women and typically exhibits a more indolent course compared to other forms of breast cancer, which allows for a variety of treatment options.
Diagnosis and Staging
The diagnosis of HR+ breast cancer begins with clinical evaluation, imaging, and biopsy. Imaging modalities such as mammography, ultrasound, and MRI help in assessing the extent of the disease. Histopathological examination and immunohistochemical staining of the biopsy sample confirm the diagnosis and hormone receptor status by identifying the presence of estrogen receptors (ER) and progesterone receptors (PR) on the tumor cells.
Staging involves determining the size of the tumor (T), the involvement of regional lymph nodes (N), and the presence of distant metastasis (M). The American Joint Committee on Cancer (AJCC) staging system is commonly used. Accurate staging is critical as it guides treatment decisions.
Treatment Options
Endocrine Therapy
Endocrine therapy is the cornerstone of treatment for HR+ breast cancer in postmenopausal women. The primary goal is to reduce the levels of estrogen or block its effects on cancer cells. Commonly used agents include:
Selective Estrogen Receptor Modulators (SERMs): Tamoxifen is a SERM that binds to estrogen receptors, blocking estrogen from stimulating breast cancer cells. It is effective but may have side effects such as increased risk of endometrial cancer and thromboembolic events.
Aromatase Inhibitors (AIs): These drugs, including anastrozole, letrozole, and exemestane, lower estrogen levels by inhibiting the aromatase enzyme, which converts androgens to estrogen in peripheral tissues. AIs are generally preferred in postmenopausal women due to their efficacy and safety profile compared to tamoxifen.
Selective Estrogen Receptor Downregulators (SERDs): Fulvestrant is a SERD that degrades estrogen receptors and is used in cases where resistance to other endocrine therapies develops.
Combination Therapies
Combining endocrine therapy with other treatments enhances efficacy. Examples include:
Endocrine Therapy with CDK4/6 Inhibitors: Palbociclib, ribociclib, and abemaciclib are CDK4/6 inhibitors that, when combined with endocrine therapy, significantly improve progression-free survival in advanced HR+ breast cancer.
Endocrine Therapy with mTOR Inhibitors: Everolimus, an mTOR inhibitor, can be added to endocrine therapy for patients who have developed resistance to aromatase inhibitors.
Chemotherapy
Chemotherapy is generally reserved for patients with high-risk features, such as large tumor size, high-grade histology, or extensive lymph node involvement. Regimens often include anthracyclines and taxanes.
Histololgy of Female Reproductive System.pptxAyeshaZaid1
Dive into an in-depth exploration of the histological structure of female reproductive system with this comprehensive lecture. Presented by Dr. Ayesha Irfan, Assistant Professor of Anatomy, this presentation covers the Gross anatomy and functional histology of the female reproductive organs. Ideal for students, educators, and anyone interested in medical science, this lecture provides clear explanations, detailed diagrams, and valuable insights into female reproductive system. Enhance your knowledge and understanding of this essential aspect of human biology.
Nano-gold for Cancer Therapy chemistry investigatory projectSIVAVINAYAKPK
chemistry investigatory project
The development of nanogold-based cancer therapy could revolutionize oncology by providing a more targeted, less invasive treatment option. This project contributes to the growing body of research aimed at harnessing nanotechnology for medical applications, paving the way for future clinical trials and potential commercial applications.
Cancer remains one of the leading causes of death worldwide, prompting the need for innovative treatment methods. Nanotechnology offers promising new approaches, including the use of gold nanoparticles (nanogold) for targeted cancer therapy. Nanogold particles possess unique physical and chemical properties that make them suitable for drug delivery, imaging, and photothermal therapy.
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These lecture slides, by Dr Sidra Arshad, offer a simplified look into the mechanisms involved in the regulation of respiration:
Learning objectives:
1. Describe the organisation of respiratory center
2. Describe the nervous control of inspiration and respiratory rhythm
3. Describe the functions of the dorsal and respiratory groups of neurons
4. Describe the influences of the Pneumotaxic and Apneustic centers
5. Explain the role of Hering-Breur inflation reflex in regulation of inspiration
6. Explain the role of central chemoreceptors in regulation of respiration
7. Explain the role of peripheral chemoreceptors in regulation of respiration
8. Explain the regulation of respiration during exercise
9. Integrate the respiratory regulatory mechanisms
10. Describe the Cheyne-Stokes breathing
Study Resources:
1. Chapter 42, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 36, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 13, Human Physiology by Lauralee Sherwood, 9th edition
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NIHSS in Stroke Severity: Why and How? presentation.pptx
1. National Institutes of Health Stroke Scale (NIHSS):
Why and How?
Dr. Md. Saiduzzaman Munna
Medical Officer
Department of Neurology
Mymensingh Medical College Hospital
Mymensingh, Bangladesh.
2. Background
It is a systematic assessment tool designed to measure the neurological deficits
in acute ischemic stroke.
First developed in 1989 as 15 item scale.
Modified NIHSS consisting 5/8/11 domains have been developed.
3. Advantages of NIHSS
Widely used, valid, reliable tool to assess stroke severity.
Low inter-personal variability.
Easy, less time consuming (even non-neurologists and nurses can
perform).
Few instruments needed (Only a pin to assess sensation).
Well matches with arteries involved.
Used to predict stroke outcome.
Used to include or exclude patients from IV thrombolysis
candidate.
4. Domains of NIHSS
1. Level of consciousness:
a) Responsiveness-
0- Alert,
1- Not alert but arousable by minor stimulation,
2- Not alert but requires repeated/strong painful stimulation for
movement,
3- Respond only with reflex motor / autonomic effects or totally
unresponsive.
5. Domains of NIHSS………
b) Questions: current month and age.
0- Answers both correctly
1- Answers one question correctly
2- Answers neither correctly.
c) Commands: Ask to open and close eyes and grip and release nonparetic hand.
0- performs both correctly.
1- performs one task correctly.
2- performs neither task correctly.
6. Domains of NIHSS………
2. Best Gaze: Test horizontal eye movement.
0- Normal.
1- Partial gaze palsy (Abnormal in one or both sides)
2- Forced deviation or total gaze paresis.
3. Visual: Visual field.
0- No visual loss.
1- Partial hemianopia.
2- Complete hemianopia.
3- Bitemporal hemianopia including cortical blindness.
7. Domains of NIHSS………
4. Facial palsy: asked to show their teeth or raise their eyebrows and close their
eyes.
0- Normal symmetrical movement.
1- Minor paralysis (asymmetry on smiling)
2- Partial paralysis (lower face).
3- Complete paralysis (both upper and lower face).
8. Domains of NIHSS………
5. Motor arm:
a) Motor arm left- Arm is extended (palms up) 90 degrees (if sitting) or 45 degrees
(if supine). Drift is scored if the arm falls before 10 seconds.
0- No drift.
1- Drifts before 10 seconds.
2- Some effort against gravity.
3- No effort against gravity.
4- No movement.
b) Motor arm right- same as a.
9. Domains of NIHSS………
6. Motor leg: Leg is raised at 30 degrees (supine). Drift is scored if the leg falls
before 5 seconds.
a) Motor leg left-
0- No drift.
1- Drifts within 5 seconds.
2. Some effort against gravity.
3- No effort against gravity.
4- No movement.
b) Motor leg right- same as a.
10. Domains of NIHSS………
7. Limb ataxia: Perform finger-nose and heel-shin test.
0- Absent/Patient paralyzed/cannot understand or amputation or joint fusion.
1- present in one limb.
2- Present in both limbs.
8. Sensory: If level of consciousness is impaired, score if a grimace or an
asymmetric withdrawal is observed.
0- No sensory loss.
1- Mild to moderate sensory loss.
2- Total sensory loss.
11. Domains of NIHSS………
9. Best language: Have the patient describe a picture/ surrounding.
0- Normal.
1- Mild to moderate aphasia.
2- Severe aphasia.
3- Global aphasia.
12. Domains of NIHSS………
10. Dysarthria: Patient is asked to read or repeat words from a list.
0- Normal or unable to test.
1- Mild to moderate dysarthria (Can be understood with some difficulty)
2- Severe dysarthria.
13. Domains of NIHSS………
11. Extinction and inattention (Neglect)
0- No abnormality.
1- Inattention or extinction to one of the sensory modalities (Visual, tactile,
auditory, spatial).
2- Profound hemi-inattention or extinction to more than one modality.