คู่มือหลักเกณฑ์การขึ้นทะเบียนตำรับยาแผนโบราณ Guideline Registration Traditional Medicine โดยกลุ่มยาแผนไทยและยาสมุนไพร สำนักยา สำนักงานคณะกรรมการอาหารและยา กระทรวงสาธารณสุข
คู่มือหลักเกณฑ์การขึ้นทะเบียนตำรับยาแผนโบราณ Guideline Registration Traditional Medicine โดยกลุ่มยาแผนไทยและยาสมุนไพร สำนักยา สำนักงานคณะกรรมการอาหารและยา กระทรวงสาธารณสุข
คู่มือมาตรฐานการผลิตยาสมุนไพร WHO guidelines on good manufacturing practices for herbal medicines สถาบันการแพทย์แผนไทย กรมการแพทย์แผนไทยและการแพทย์ทางเลือก กระทรวงสาธารณสุข
This document discusses different types of pallets used for transporting goods, including wood, plastic, and metal pallets. It notes that wood pallets are most common but can develop problems like splitting or warping over time from weather or rough handling. The document also briefly mentions some challenges with other pallet materials as well as potential side effects from certain drugs.
Sin eng-26 - change your attitude revision tipssochinaction
The document provides tips for effective studying including taking good notes in class, asking questions, highlighting important text, managing time well with revision starting two months before exams, reading textbooks actively by reciting and reviewing rather than passive re-reading, studying harder subjects first, studying in a quiet place without distractions, carefully reading and reviewing exam questions, eating and sleeping well, and understanding that good results require consistent hard work and dedicating sufficient time to studying over quick and easy methods.
The document discusses the process of making fine Cuban cigars from growing and harvesting tobacco to aging, rolling, quality control, and packaging cigars. It takes over 250 labor intensive steps and over 3 years to produce a fine Cuban cigar. The document also briefly mentions cigar etiquette, accessories like humidors and cutters, and ends by introducing single malt whisky.
คู่มือมาตรฐานการผลิตยาสมุนไพร WHO guidelines on good manufacturing practices for herbal medicines สถาบันการแพทย์แผนไทย กรมการแพทย์แผนไทยและการแพทย์ทางเลือก กระทรวงสาธารณสุข
This document discusses different types of pallets used for transporting goods, including wood, plastic, and metal pallets. It notes that wood pallets are most common but can develop problems like splitting or warping over time from weather or rough handling. The document also briefly mentions some challenges with other pallet materials as well as potential side effects from certain drugs.
Sin eng-26 - change your attitude revision tipssochinaction
The document provides tips for effective studying including taking good notes in class, asking questions, highlighting important text, managing time well with revision starting two months before exams, reading textbooks actively by reciting and reviewing rather than passive re-reading, studying harder subjects first, studying in a quiet place without distractions, carefully reading and reviewing exam questions, eating and sleeping well, and understanding that good results require consistent hard work and dedicating sufficient time to studying over quick and easy methods.
The document discusses the process of making fine Cuban cigars from growing and harvesting tobacco to aging, rolling, quality control, and packaging cigars. It takes over 250 labor intensive steps and over 3 years to produce a fine Cuban cigar. The document also briefly mentions cigar etiquette, accessories like humidors and cutters, and ends by introducing single malt whisky.
Este documento describe la inclusión de tendencias pedagógicas innovadoras como el aprendizaje basado en proyectos, el aprendizaje vivencial y el aprendizaje invertido en las clases de inglés en los grados 10 y 11 de una escuela. El autor explica el contexto diverso de la escuela y la necesidad de motivar a los estudiantes. Se detallan actividades como la producción de videos, intercambios culturales y la creación de autobiografías basadas en modelos en línea. El documento concluye que estas tendencias promueven
This document describes the challenges of accurately reporting energy usage costs and carbon savings across different geographic locations with variable electricity tariffs. It explains how factors like electricity prices, carbon dioxide emission rates, and utility rebates vary in different places. The NightWatchman 6 software addresses this by allowing users to define tariffs for locations that specify the cost per kWh, carbon conversion rate, and utility provider. This enables NightWatchman to accurately calculate and report costs, emissions, and savings at each location.
Este documento presenta un portafolio de proyectos de diseño realizados en Google SketchUp por un estudiante para su clase de Informática en el Instituto Orestes Sindici. Los proyectos incluyen diseños de un estadio, una casa, proyectos libres y una réplica.
H&M had a very expansive year in 2015 with sales totaling SEK 210 billion, a 19% increase. However, the stronger US dollar negatively impacted purchasing costs and raw material prices. For 2016, H&M plans to increase stores by 10-15% and add 11 new online markets, bringing the total to 34 countries online. It also aims to reduce pollution from chemical products and work with authorities to improve environmental practices across its value chain.
Questionnaire intercultural dimension in Europe “Italian contribution”OLEtark
This document summarizes the responses from a questionnaire given to 23 people in Italy about their views on immigration and multiculturalism. The majority of respondents considered their community to be multicultural. Opinions were split on the size of the immigrant population, with about half seeing it as small/very small and half seeing it as big/very big. Most respondents believed immigrants peacefully coexisted with the majority and that immigration had little to no effect on unemployment. Respondents also generally agreed immigrants made positive economic and cultural contributions.
Application of biopharmaceutics classification system in formulation developm...Surang Judistprasert
The document discusses the application of the Biopharmaceutics Classification System (BCS) in formulation development. It describes the four BCS classes based on a drug's solubility and permeability properties and how these properties impact bioequivalence studies and regulatory requirements. It also discusses factors that influence the predictability of in vivo performance based on the BCS class, such as first-pass metabolism and excipient effects. Recommendations are provided for designing successful bioequivalence studies using BCS principles.
The document discusses using 7QC tools for experiment design and problem solving. It lists 7QC tools like Pareto charts, histograms, process flow diagrams, check sheets, scatter diagrams, control charts, and run charts. These tools can be applied in design of experiments (DOE) to investigate the relationship between input attributes, process parameters, and output attributes. Minitab software can be used for DOE. Results from DOE like scatter diagrams can study the effect of parameters on quality attributes. Pareto charts can identify and prioritize problems, showing that 20% of causes often create 80% of issues. The document gives an example of using these tools to analyze quality problems with ACE tablets.
This document discusses Quality by Design (QbD) and how to implement it in a practical way. It defines QbD and outlines the key steps, which include establishing a target product profile, identifying critical quality attributes, defining a design space, control strategy, validation, and lifecycle management. Design spaces can be defined using design of experiments or multivariate analysis of historical data. Tools like DOE and MVA are useful for establishing and monitoring the design space. The document provides an example target product profile and discusses how to set the profile and manufacturing process scheme based on the active pharmaceutical ingredient's properties. It also discusses using risk assessment to identify critical variables and control strategies. The overall goal is developing a robust process understanding and control
Thai version. This material was for 3rd seminar last year. I would like to introduce innovation management for our colleague and challenged them in knowledge management in our department.
This document summarizes a presentation on quality culture given at the 2012 CGMP Conference in Baltimore. The presentation discusses the importance of quality culture in protecting patient safety and product quality across complex pharmaceutical supply chains. It defines quality culture as an environment where everyone understands and embraces their responsibility for quality. Strong quality culture is identified as the most important indicator of an organization's ability to consistently deliver high quality products and services.
The document discusses alternative materials to gelatin capsules, including starch and HPMC capsules. It describes how starch capsules are produced via injection molding and have similar fill volumes to gelatin capsules. HPMC capsules are made using the same process as gelatin capsules. The document also provides details on the manufacture and benefits of soft gelatin capsules, which combine advantages of liquid and solid dosage forms. Soft gelatin capsules offer improved content uniformity, safety, stability, and bioavailability compared to other forms.
This document discusses study design considerations for comparing topical dosage forms in vitro and in vivo. It outlines three methods approved by the Thai FDA to check bioequivalence of topical drugs: in vitro drug release testing using Franz cell diffusion, pharmacodynamic studies measuring physiological effects, and clinical trials. The US FDA only approves clinical trials. In vitro methods are useful but human studies with 100-4000 subjects are ultimately needed to adequately assess bioequivalence of topical dosage forms.