1) Back injuries are common, costly workplace injuries that affect over 1 million workers annually and are difficult to heal from, increasing risk of re-injury.
2) The spine's vertebrae, discs, ligaments and muscles can be damaged from repetitive bending, lifting, or stress over time, especially with poor form or excessive weight.
3) Maintaining good posture, physical fitness, weight management and following basic lifting techniques can help prevent back strain or injury.
Bodyaline 10 back saving tips youve never heard before eb… 3Robert Gearhart
10 Easy to use back saving tips to help reduce or eliminate back pain and to aid in posture correction. Back pain is the second most common reason for a doctor visit next to the common cold. Simple tips like these can help improve your posture, prevent back pain, and keep you out of the doctors office.
DISSERTATION on NEW DRUG DISCOVERY AND DEVELOPMENT STAGES OF DRUG DISCOVERYNEHA GUPTA
The process of drug discovery and development is a complex and multi-step endeavor aimed at bringing new pharmaceutical drugs to market. It begins with identifying and validating a biological target, such as a protein, gene, or RNA, that is associated with a disease. This step involves understanding the target's role in the disease and confirming that modulating it can have therapeutic effects. The next stage, hit identification, employs high-throughput screening (HTS) and other methods to find compounds that interact with the target. Computational techniques may also be used to identify potential hits from large compound libraries.
Following hit identification, the hits are optimized to improve their efficacy, selectivity, and pharmacokinetic properties, resulting in lead compounds. These leads undergo further refinement to enhance their potency, reduce toxicity, and improve drug-like characteristics, creating drug candidates suitable for preclinical testing. In the preclinical development phase, drug candidates are tested in vitro (in cell cultures) and in vivo (in animal models) to evaluate their safety, efficacy, pharmacokinetics, and pharmacodynamics. Toxicology studies are conducted to assess potential risks.
Before clinical trials can begin, an Investigational New Drug (IND) application must be submitted to regulatory authorities. This application includes data from preclinical studies and plans for clinical trials. Clinical development involves human trials in three phases: Phase I tests the drug's safety and dosage in a small group of healthy volunteers, Phase II assesses the drug's efficacy and side effects in a larger group of patients with the target disease, and Phase III confirms the drug's efficacy and monitors adverse reactions in a large population, often compared to existing treatments.
After successful clinical trials, a New Drug Application (NDA) is submitted to regulatory authorities for approval, including all data from preclinical and clinical studies, as well as proposed labeling and manufacturing information. Regulatory authorities then review the NDA to ensure the drug is safe, effective, and of high quality, potentially requiring additional studies. Finally, after a drug is approved and marketed, it undergoes post-marketing surveillance, which includes continuous monitoring for long-term safety and effectiveness, pharmacovigilance, and reporting of any adverse effects.
- Video recording of this lecture in English language: https://youtu.be/kqbnxVAZs-0
- Video recording of this lecture in Arabic language: https://youtu.be/SINlygW1Mpc
- Link to download the book free: https://nephrotube.blogspot.com/p/nephrotube-nephrology-books.html
- Link to NephroTube website: www.NephroTube.com
- Link to NephroTube social media accounts: https://nephrotube.blogspot.com/p/join-nephrotube-on-social-media.html
Here is the updated list of Top Best Ayurvedic medicine for Gas and Indigestion and those are Gas-O-Go Syp for Dyspepsia | Lavizyme Syrup for Acidity | Yumzyme Hepatoprotective Capsules etc
Recomendações da OMS sobre cuidados maternos e neonatais para uma experiência pós-natal positiva.
Em consonância com os ODS – Objetivos do Desenvolvimento Sustentável e a Estratégia Global para a Saúde das Mulheres, Crianças e Adolescentes, e aplicando uma abordagem baseada nos direitos humanos, os esforços de cuidados pós-natais devem expandir-se para além da cobertura e da simples sobrevivência, de modo a incluir cuidados de qualidade.
Estas diretrizes visam melhorar a qualidade dos cuidados pós-natais essenciais e de rotina prestados às mulheres e aos recém-nascidos, com o objetivo final de melhorar a saúde e o bem-estar materno e neonatal.
Uma “experiência pós-natal positiva” é um resultado importante para todas as mulheres que dão à luz e para os seus recém-nascidos, estabelecendo as bases para a melhoria da saúde e do bem-estar a curto e longo prazo. Uma experiência pós-natal positiva é definida como aquela em que as mulheres, pessoas que gestam, os recém-nascidos, os casais, os pais, os cuidadores e as famílias recebem informação consistente, garantia e apoio de profissionais de saúde motivados; e onde um sistema de saúde flexível e com recursos reconheça as necessidades das mulheres e dos bebês e respeite o seu contexto cultural.
Estas diretrizes consolidadas apresentam algumas recomendações novas e já bem fundamentadas sobre cuidados pós-natais de rotina para mulheres e neonatos que recebem cuidados no pós-parto em unidades de saúde ou na comunidade, independentemente dos recursos disponíveis.
É fornecido um conjunto abrangente de recomendações para cuidados durante o período puerperal, com ênfase nos cuidados essenciais que todas as mulheres e recém-nascidos devem receber, e com a devida atenção à qualidade dos cuidados; isto é, a entrega e a experiência do cuidado recebido. Estas diretrizes atualizam e ampliam as recomendações da OMS de 2014 sobre cuidados pós-natais da mãe e do recém-nascido e complementam as atuais diretrizes da OMS sobre a gestão de complicações pós-natais.
O estabelecimento da amamentação e o manejo das principais intercorrências é contemplada.
Recomendamos muito.
Vamos discutir essas recomendações no nosso curso de pós-graduação em Aleitamento no Instituto Ciclos.
Esta publicação só está disponível em inglês até o momento.
Prof. Marcus Renato de Carvalho
www.agostodourado.com
These lecture slides, by Dr Sidra Arshad, offer a quick overview of the physiological basis of a normal electrocardiogram.
Learning objectives:
1. Define an electrocardiogram (ECG) and electrocardiography
2. Describe how dipoles generated by the heart produce the waveforms of the ECG
3. Describe the components of a normal electrocardiogram of a typical bipolar lead (limb II)
4. Differentiate between intervals and segments
5. Enlist some common indications for obtaining an ECG
6. Describe the flow of current around the heart during the cardiac cycle
7. Discuss the placement and polarity of the leads of electrocardiograph
8. Describe the normal electrocardiograms recorded from the limb leads and explain the physiological basis of the different records that are obtained
9. Define mean electrical vector (axis) of the heart and give the normal range
10. Define the mean QRS vector
11. Describe the axes of leads (hexagonal reference system)
12. Comprehend the vectorial analysis of the normal ECG
13. Determine the mean electrical axis of the ventricular QRS and appreciate the mean axis deviation
14. Explain the concepts of current of injury, J point, and their significance
Study Resources:
1. Chapter 11, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 9, Human Physiology - From Cells to Systems, Lauralee Sherwood, 9th edition
3. Chapter 29, Ganong’s Review of Medical Physiology, 26th edition
4. Electrocardiogram, StatPearls - https://www.ncbi.nlm.nih.gov/books/NBK549803/
5. ECG in Medical Practice by ABM Abdullah, 4th edition
6. Chapter 3, Cardiology Explained, https://www.ncbi.nlm.nih.gov/books/NBK2214/
7. ECG Basics, http://www.nataliescasebook.com/tag/e-c-g-basics
Local Advanced Lung Cancer: Artificial Intelligence, Synergetics, Complex Sys...Oleg Kshivets
Overall life span (LS) was 1671.7±1721.6 days and cumulative 5YS reached 62.4%, 10 years – 50.4%, 20 years – 44.6%. 94 LCP lived more than 5 years without cancer (LS=2958.6±1723.6 days), 22 – more than 10 years (LS=5571±1841.8 days). 67 LCP died because of LC (LS=471.9±344 days). AT significantly improved 5YS (68% vs. 53.7%) (P=0.028 by log-rank test). Cox modeling displayed that 5YS of LCP significantly depended on: N0-N12, T3-4, blood cell circuit, cell ratio factors (ratio between cancer cells-CC and blood cells subpopulations), LC cell dynamics, recalcification time, heparin tolerance, prothrombin index, protein, AT, procedure type (P=0.000-0.031). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and N0-12 (rank=1), thrombocytes/CC (rank=2), segmented neutrophils/CC (3), eosinophils/CC (4), erythrocytes/CC (5), healthy cells/CC (6), lymphocytes/CC (7), stick neutrophils/CC (8), leucocytes/CC (9), monocytes/CC (10). Correct prediction of 5YS was 100% by neural networks computing (error=0.000; area under ROC curve=1.0).
263778731218 Abortion Clinic /Pills In Harare ,sisternakatoto
263778731218 Abortion Clinic /Pills In Harare ,ABORTION WOMEN’S CLINIC +27730423979 IN women clinic we believe that every woman should be able to make choices in her pregnancy. Our job is to provide compassionate care, safety,affordable and confidential services. That’s why we have won the trust from all generations of women all over the world. we use non surgical method(Abortion pills) to terminate…Dr.LISA +27730423979women Clinic is committed to providing the highest quality of obstetrical and gynecological care to women of all ages. Our dedicated staff aim to treat each patient and her health concerns with compassion and respect.Our dedicated group ABORTION WOMEN’S CLINIC +27730423979 IN women clinic we believe that every woman should be able to make choices in her pregnancy. Our job is to provide compassionate care, safety,affordable and confidential services. That’s why we have won the trust from all generations of women all over the world. we use non surgical method(Abortion pills) to terminate…Dr.LISA +27730423979women Clinic is committed to providing the highest quality of obstetrical and gynecological care to women of all ages. Our dedicated staff aim to treat each patient and her health concerns with compassion and respect.Our dedicated group of receptionists, nurses, and physicians have worked together as a teamof receptionists, nurses, and physicians have worked together as a team wwww.lisywomensclinic.co.za/
Ozempic: Preoperative Management of Patients on GLP-1 Receptor Agonists Saeid Safari
Preoperative Management of Patients on GLP-1 Receptor Agonists like Ozempic and Semiglutide
ASA GUIDELINE
NYSORA Guideline
2 Case Reports of Gastric Ultrasound
Rasamanikya is a excellent preparation in the field of Rasashastra, it is used in various Kushtha Roga, Shwasa, Vicharchika, Bhagandara, Vatarakta, and Phiranga Roga. In this article Preparation& Comparative analytical profile for both Formulationon i.e Rasamanikya prepared by Kushmanda swarasa & Churnodhaka Shodita Haratala. The study aims to provide insights into the comparative efficacy and analytical aspects of these formulations for enhanced therapeutic outcomes.
2. BACK SAFETY Or … How to prevent a lifetime of back problems
3.
4.
5.
6.
7.
8.
9.
10.
11. NEMT Solutions, LLC Why do they occur? You’re right! It takes 10 pounds of pressure to lift a 10 pound object. Will it take more or less force to lift the same 10 pound object with the fulcrum shifted to one side?
12. NEMT Solutions, LLC Why do they occur? You’re right! With the fulcrum shifted away from the object, it takes more force to lift the object. The human back operates on a 10:1 ratio, with the waist acting as the fulcrum.
13. NEMT Solutions, LLC Why do they occur? When you add in the 105 pounds of the average human upper torso, lifting a 10 pound object puts 1,150 pounds of pressure on the human back.
14. NEMT Solutions, LLC Why do they occur? If you were 25 pounds overweight, it would put an additional 250 pounds of pressure on your back every time you bend over.
15. NEMT Solutions, LLC Why do they occur? Now it’s easy to see how repetitive bending and lifting can quickly cause back problems. Even leaning forward while sitting at a desk or table can eventually cause damage and pain.
16. NEMT Solutions, LLC Contributing Factors Poor Physical Condition Your stomach muscles provide a lot of the support needed by your back. If you have weak, flabby stomach muscles, your back may not get all the support it needs, especially when you're lifting or carrying heavy objects. Good physical condition in general is important for preventing strains, sprains, and other injuries.
17. NEMT Solutions, LLC Contributing Factors Poor posture… is another contributing factor. When your mother told you to sit and stand up straight, she was giving you good advice. It is best to try to maintain the back in its natural "S" shaped curve. You want to avoid leaning forward (unsupported) when you sit, or hunching over while you're standing.
18. NEMT Solutions, LLC Contributing Factors Extra weight… can be a big problem. Remember the fulcrum / lever principle? The more you weigh, the more stress it puts on your back every time you bend over--on a 10:1 ratio. That pot belly is not helping the health of your back.
19. NEMT Solutions, LLC Contributing Factors Stress - Tense muscles are more susceptible to strains and spasms.
20. NEMT Solutions, LLC Contributing Factors Overdoing it - Don’t be afraid to say, “This is too heavy for me to lift alone.” It’s important to recognize your physical limitations and abilities. Many people have injured their backs because they were afraid to ask for help.
21. NEMT Solutions, LLC Common Causes Many back injuries tend to be the result of cumulative damage suffered over a long period of time. Certain actions, motions and movements are more likely than others to cause or contribute to back injuries…
22. NEMT Solutions, LLC Common Causes Any time you find yourself doing one of these things, you should think: DANGER! My back is at risk!
23. NEMT Solutions, LLC Common Causes Heavy Lifting … especially repetitive lifting over a long period of time…
24. NEMT Solutions, LLC Common Causes Twisting at the waist … while lifting or holding a heavy load…
25. NEMT Solutions, LLC Common Causes Reaching and lifting … over your head, across a table, or out the back of a truck…
26. NEMT Solutions, LLC Common Causes Lifting or carrying objects with awkward or odd shapes…
27. NEMT Solutions, LLC Common Causes Working in odd, uncomfortable positions … gardening, kneeling, tasks that require you to bend over for long periods of time…
28. NEMT Solutions, LLC Common Causes Sitting or standing too long in one position … (sitting can be very hard on the lower back)…
29. NEMT Solutions, LLC Common Causes It is also possible to injure your back slipping on a wet floor or ice.
30. NEMT Solutions, LLC Common Causes Some people suffer back pain because they sleep in a bad position, or because their mattress is too soft.
31.
32. NEMT Solutions, LLC Common Causes #2 is right! If you've been waking up with a sore or painful back, you might try sleeping on your side with your knees slightly bent, or on your back with a small pillow under your knees. You can try putting boards under your old mattress or maybe try a new one. Of course, it’s always wise to check with your doctor about any sort of health problem.
33. NEMT Solutions, LLC Prevent Back Injuries The best way to prevent back injuries is to develop habits that reduce the strain placed on the back. There are some basic things you can do to help.
34.
35.
36.
37.
38.
39.
40.
41.
42. NEMT Solutions, LLC Prevent Back Injuries Also follow these lifting tips: Reduce the amount of weight lifted. If you're moving a bunch of books, better to load several small boxes than one extremely heavy load. Use handles and lifting straps. Get help if the shape is too awkward or the object is too heavy for you to lift and move by yourself!
43. NEMT Solutions, LLC Prevent Back Injuries Body Management: It's important to know your body's limitations, and it's important to be aware of your body position at all times. Learn to recognize those situations where your back is most a risk: bending, lifting, reaching, twisting, etc. Then take measures to avoid an injury.
44. NEMT Solutions, LLC Prevent Back Injuries Body Management: Stretch first – If you know that you're going to be doing work that might be hard on your back, take the time to stretch your muscles before starting, just like a professional athlete would do before a workout. This will help you avoid painful strains and sprains.
45. NEMT Solutions, LLC Prevent Back Injuries Body Management: Slow down – If you're doing a lot of heavy, repetitive lifting, take it slowly if you can. Allow yourself more recovery time between lifts, as well. Don't overdo it.
46. NEMT Solutions, LLC Prevent Back Injuries Body Management: Rest your back – Take frequent, short (micro) breaks. Stretch. If you've ever been working in an awkward position for a long time, then stood up and felt stiff and sore, you know you've been in that position too long, and your body is now protesting. Taking a one minute stretch break every now and then can help you avoid that.
47. NEMT Solutions, LLC Prevent Back Injuries Body Management: Sleep on a firm mattress. – Also, the best sleeping position for many people is either on the back with the knees slightly elevated (by a pillow), or on the side with knees slightly bent.
48. NEMT Solutions, LLC Prevent Back Injuries Body Management: Get in shape – Strengthen your stomach muscles, lose a little weight, increase your flexibility.
49. Exam - Back Injuries Click on the link below for exam: Back Injuries Exam