This document provides information on xylometazoline hydrochloride nasal spray/drops, including its composition, mechanism of action, usage, storage conditions, side effects, precautions, rates, MRP, and packing. Xylometazoline is a topical nasal decongestant used to relieve nasal congestion from colds, allergies, and sinusitis. It works by constricting nasal blood vessels. Common side effects include nasal irritation and dryness.
drug relative to eyes with their meiotic and mydriatic effect.
In the presentation discus about spasm of accommodation and cycloplegic action on eye . pharmacological action , dosage also discussed of condition developed on eye i.e. Glaucoma
Hyocimax (Generic Hyoscine Butylbromide Tablets) is a treatment for the relief of smooth muscle spasm/cramping of the gastrointestinal system and its associated pain and discomfort.
It can also be used to relieve the abdominal cramps which cause pain and discomfort associated with Irritable Bowel Syndrome (IBS).
Pharmaceutical Quality Management of Dexamethasone tablets BP
Dexamethasone tablets USP
DEXAMETHSONE OPTHALMIC SUSPENSION BP
DEXAMETHSONE OPTHALMIC SUSPENSION USP
Dexamethasone is a synthetic (man-made) corticosteroid.
Corticosteroids are naturally-occurring chemicals produced by the adrenal glands located above the kidneys.
drug relative to eyes with their meiotic and mydriatic effect.
In the presentation discus about spasm of accommodation and cycloplegic action on eye . pharmacological action , dosage also discussed of condition developed on eye i.e. Glaucoma
Hyocimax (Generic Hyoscine Butylbromide Tablets) is a treatment for the relief of smooth muscle spasm/cramping of the gastrointestinal system and its associated pain and discomfort.
It can also be used to relieve the abdominal cramps which cause pain and discomfort associated with Irritable Bowel Syndrome (IBS).
Pharmaceutical Quality Management of Dexamethasone tablets BP
Dexamethasone tablets USP
DEXAMETHSONE OPTHALMIC SUSPENSION BP
DEXAMETHSONE OPTHALMIC SUSPENSION USP
Dexamethasone is a synthetic (man-made) corticosteroid.
Corticosteroids are naturally-occurring chemicals produced by the adrenal glands located above the kidneys.
2. Composition
Adult Composition…..
Xylometazoline Hydrochloride IP 0.1%w/v
Benzalkonium Chloride IP 0.01%w/v
(As Preservative)
An aqueous isotonic solution using
Purified Water.. IP q.s
•
Pediatric composition…….
Xylometazoline Hydrochloride IP 0.05 % w/v
Benzalkonium Chloride IP 0.01% w/v
(As Preservative)
An aqueous isotonic solution using IP q.s
Purified Water..
3.
4.
5. Xylometazoline (also known as xylomethazoline) is a
drug which is used as a topical nasal decongestant. It
is applied directly into the nose, either as a spray or as
drops
Xylometazoline is marketed under many brand
names with the typical adult solution strength being
0.1% w/v xylometazoline, and the dose for children
under 12 being 0.05%
6. Mechanism of Action
• The drug works by
constricting the blood vessels
in the nose. The
vasoconstriction means that
there is less pressure in the
capillaries and less water can
filter out, thus less discharge is
made. (If the colour of the nasal
passage is observed, it is
visibly paler after dosage.)
• Xylometazoline is an imidazole
derivative which is designed to
mimic the molecular shape of
adrenaline. It binds to
alpha-adrenergic receptors in
the nasal mucosa.
7. Xylometazoline Nasal spray is used for:
• Nasal congestion
• Common cold
• Sinusitis
• Nasal allergies (allergic rhinitis)
• Xylometazoline is used to help clear the
stuffy, blocked up feeling in the nose
and sinuses caused by colds
and allergies such as hayfever.
8. Usage
• One spray should be used in each
nostril one to three times a day as
necessary.
• The spray can be used for up to a week.
Storage Condition
• Keep all medicines out of the reach and
sight of children.
• Store in a cool, dry place, away from direct
heat and light.
10. Precautions
• Do NOT use Xylometazoline spray if
• If you are pregnant or breast-feeding.
• If you have diabetes, high blood pressure,
• If you have ever had an allergic reaction to
this or to any other medicine.
• If you are taking any other medicines,
including those available to buy without a
prescription. You must not use
xylometazoline if you have taken a
11. Rates,Mrp and Packing
• Rates 7.50/wc in 10ml for 0.1%
• Mrp 40 to 55
• Rates 7.25/wc in 10ml for 0.05%
• Mrp 25 to 35
• Expiry 2 years
• Bottle oval shaped white HDPE.