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CASE PRESENTATION




     6
CASE
Case                  48


                       10
         2555
   30

                90%
CHIEF COMPLAINT
              5
 PTA
PRESSENT ILLNESS
5       PTA
           3         5
     8         6-7




2       PTA

                         DMPA
PRESSENT ILLNESS





PAST HISTORY
U/D Thyroid
                     6   PTA
P3003 last 20


LMP 4-8      55 (5 days/28-30 days/
  3pads per day)
PMP
FAMILY HISTORY







PERSONAL HISTORY




PHYSICAL EXAMINATION
Vital signs
  BP 110/50 mmHg              PR 72 /min
  RR 18 /min            BT 37 c
GA
  Good consciousness, mild pale, no jaundice, no
   cyanosis, no edema
HEENT
  Mile pale conjunctivae, no icteric sclerae
Cardiovascular
  Pulse full and regular, normal S1S2, no murmur
PHYSICAL EXAMINATION
Lung
  Equal chest expansion, clear, no adventitous sound
Abdomen
  No distention, Normoactive bowel sound, soft,,
   palpable midline pelvic mass size 2/3> PS, globular
   shape, irregular surface, rubbery, not tender, movable
   no rebound tenderness
Neurological
  Grossly intact
Extremities
  No edema, no fracture
PHYSICAL EXAMINATION
Per vagina examination :
  MIUB   -   Normal
  Vg     -   No discharge, no lesion
  Cx     -   No mass and polyps, closed
  Ut     -   16 wk. size with globular mass at fundus
  Adn    -   No palpable mass, no tenderness
  CDS    -   No bulging
PERTINENT FINDING
An middle aged Thai woman 48 years
Perimenopausal period
Abnormal uterine bleeding
Abdominal mass
Anemic symptoms
Underlying Thyroid disease (Clinical Euthyroid)
 s/p Surgery 6 years PTA
PROBLEM LIST
 Abdominal mass with Abnormal uterine
  bleeding and anemic symptoms

 Underlying Thyroid disease Clinical
  euthyroid s/p Surgery 6 years PTA
APPROACH AUB
APPROACH AUB
Causes of menorrhagia
DIFFERENTIAL DIAGNOSIS
Uterus mass (leiomyoma vs leiomyosarcoma)
Adenomyosis
Ovarian tumor
Endometrium disease
Cervical cancer
Systemic conditions
  Hypothyroid
  Coagulopathies
INVESTIGATION

CBC
  Hb     10.0 g/dl     WBC    6,500 /ul
  HCT    29.0 %        PMN    58.0 %
  MCV    55.0 fl       Lymp   39.0 %
  MCH    19.  pg       Mono   1.0 %
  MCHC   35.1 g/dl     Eo     2.0   %
  Plt    208,000 /ul   Baso   0     %
INVESTIGATION
PBS
  RBC Morphology          Abnormal RBC
  Microcytic              1+
  Hypochromic 1+
  Target cell, schitocyte Few


Thyroid function test
  FT3     2.245 (1.21-4.18) mmol/l
  FT4     14.25 (7.2-17.2) mmol/l
INVESTIGATION
 UA
    Color/Appearance   Y/C
    pH                 7
    Ketone             Neg
    Protein            Neg
    Nitrite            Neg
    Glucose            Norm
    WBC                0-1
    RBC                0-1
    Sq.epithelium      10-20
    Bacteria           -
INVESTIGATION
 Coagulogram   normal
 BS            86 mg/dl
 BUN           10 mg/dl
 Creatinine    0.7 mg/dl
 Anti-HIV      negative
 CXR           normal
 EKG           normal sinus rhythm, rate 70/min
INVESTIGATION
PAP smear

 Negative for intraepithelial lesion or malignancy but
  reactive cellular change associate with inflammation

Endometrium Biopsy

 Inactive endometrium
INVESTIGATION
Ultrasound
-
TREATMENT (11/12/2555)
 Total abdominal hysterectomy with bilateral
  salpingooophorectomy

   Uterus 16 wk size with large intramural myoma at fundus 8x8 cm.
    and intramural myoma 4x4 cm. at anterior of body of uterus
   Both normal
   Normal liver and spleen
   Normal omentum
   No immediate comlication
   Estimate blood loss 800 ml.
TREATMENT (11/12/2555)
PROGRESS NOTE (12/12/2555)
 S:

                          Hct 35 vol%
 O: V/S BP 100/40 mmHg RR 18 /min
            PR 90/min        BT 36.5 c
      Abd soft, normoactive bowel sound, no
          tenderness, no active bleeding
 A+P :
   Multiple myoma with hypermenorrhea S/P TAH c BSO day 1 :
    clinical stable
        Step diet
        Off IV+Foley
        Pain control
PROGRESS NOTE (13/12/2555)
 S:
 O:   v/s    BP 100/50 mmHg          RR 18 /min
              PR 72/min        BT 36.8 c
       Abd   soft, normoactive bowel sound, no
             tenderness, no active bleeding
 A+P :
   Multiple myoma with hypermenorrhea S/P TAH c BSO
    day 2 : clinical stable
      Observe bleeding
      Pain control
      Plan discharge

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Myoma uteri presentation

  • 2. CASE Case 48   10 2555  30  90%
  • 4. PRESSENT ILLNESS 5 PTA 3 5 8 6-7 2 PTA DMPA
  • 6. PAST HISTORY U/D Thyroid 6 PTA P3003 last 20   LMP 4-8 55 (5 days/28-30 days/ 3pads per day) PMP
  • 9. PHYSICAL EXAMINATION Vital signs  BP 110/50 mmHg PR 72 /min  RR 18 /min BT 37 c GA  Good consciousness, mild pale, no jaundice, no cyanosis, no edema HEENT  Mile pale conjunctivae, no icteric sclerae Cardiovascular  Pulse full and regular, normal S1S2, no murmur
  • 10. PHYSICAL EXAMINATION Lung  Equal chest expansion, clear, no adventitous sound Abdomen  No distention, Normoactive bowel sound, soft,, palpable midline pelvic mass size 2/3> PS, globular shape, irregular surface, rubbery, not tender, movable no rebound tenderness Neurological  Grossly intact Extremities  No edema, no fracture
  • 11. PHYSICAL EXAMINATION Per vagina examination :  MIUB - Normal  Vg - No discharge, no lesion  Cx - No mass and polyps, closed  Ut - 16 wk. size with globular mass at fundus  Adn - No palpable mass, no tenderness  CDS - No bulging
  • 12. PERTINENT FINDING An middle aged Thai woman 48 years Perimenopausal period Abnormal uterine bleeding Abdominal mass Anemic symptoms Underlying Thyroid disease (Clinical Euthyroid) s/p Surgery 6 years PTA
  • 13. PROBLEM LIST  Abdominal mass with Abnormal uterine bleeding and anemic symptoms  Underlying Thyroid disease Clinical euthyroid s/p Surgery 6 years PTA
  • 17. DIFFERENTIAL DIAGNOSIS Uterus mass (leiomyoma vs leiomyosarcoma) Adenomyosis Ovarian tumor Endometrium disease Cervical cancer Systemic conditions  Hypothyroid  Coagulopathies
  • 18. INVESTIGATION CBC  Hb 10.0 g/dl WBC 6,500 /ul  HCT 29.0 % PMN 58.0 %  MCV 55.0 fl Lymp 39.0 %  MCH 19. pg Mono 1.0 %  MCHC 35.1 g/dl Eo 2.0 %  Plt 208,000 /ul Baso 0 %
  • 19. INVESTIGATION PBS  RBC Morphology Abnormal RBC  Microcytic 1+  Hypochromic 1+  Target cell, schitocyte Few Thyroid function test  FT3 2.245 (1.21-4.18) mmol/l  FT4 14.25 (7.2-17.2) mmol/l
  • 20. INVESTIGATION  UA  Color/Appearance Y/C  pH 7  Ketone Neg  Protein Neg  Nitrite Neg  Glucose Norm  WBC 0-1  RBC 0-1  Sq.epithelium 10-20  Bacteria -
  • 21. INVESTIGATION  Coagulogram normal  BS 86 mg/dl  BUN 10 mg/dl  Creatinine 0.7 mg/dl  Anti-HIV negative  CXR normal  EKG normal sinus rhythm, rate 70/min
  • 22. INVESTIGATION PAP smear  Negative for intraepithelial lesion or malignancy but reactive cellular change associate with inflammation Endometrium Biopsy  Inactive endometrium
  • 24. TREATMENT (11/12/2555)  Total abdominal hysterectomy with bilateral salpingooophorectomy  Uterus 16 wk size with large intramural myoma at fundus 8x8 cm. and intramural myoma 4x4 cm. at anterior of body of uterus  Both normal  Normal liver and spleen  Normal omentum  No immediate comlication  Estimate blood loss 800 ml.
  • 26. PROGRESS NOTE (12/12/2555)  S: Hct 35 vol%  O: V/S BP 100/40 mmHg RR 18 /min PR 90/min BT 36.5 c Abd soft, normoactive bowel sound, no tenderness, no active bleeding  A+P :  Multiple myoma with hypermenorrhea S/P TAH c BSO day 1 : clinical stable  Step diet  Off IV+Foley  Pain control
  • 27. PROGRESS NOTE (13/12/2555)  S:  O: v/s BP 100/50 mmHg RR 18 /min PR 72/min BT 36.8 c Abd soft, normoactive bowel sound, no tenderness, no active bleeding  A+P :  Multiple myoma with hypermenorrhea S/P TAH c BSO day 2 : clinical stable  Observe bleeding  Pain control  Plan discharge