This document discusses the use of array comparative genomic hybridization (aCGH) for preimplantation genetic diagnosis (PGD) and screening (PGS). It finds that aCGH allows for high-resolution screening of chromosomal abnormalities, including aneuploidies and microdeletions. While it cannot detect balanced rearrangements, aCGH has advantages over techniques like fluorescence in situ hybridization (FISH) and can analyze more of the genome. The document also presents the author's own findings that aCGH-PGS may improve pregnancy and implantation rates compared to no PGS or FISH-PGS. Overall, aCGH is presented as a suitable approach for PGD/PGS