The document discusses Most Significant Change (MSC) stories, which are used to identify and reflect on progress in research for development projects. MSC stories should focus on five domains of change: relations, knowledge, attitudes, skills and practices, and research approach. Staff are asked to identify the most important activities and interactions with target groups and any related changes in these domains, who benefits from the changes, and why the changes are significant. The document also asks for feedback on using MSC stories as a tool and whether any common themes emerged from Mekong MSC stories.