This document discusses monkeypox transmission and prevention. It notes that monkeypox can spread through direct contact with monkeypox rash, scabs, or body fluids, or through contact with contaminated objects. A person is contagious from when symptoms start until the rash is fully healed. The document provides guidance on infection control in healthcare settings, including use of personal protective equipment and isolation precautions. It also provides guidance for safely isolating and caring for people with suspected or confirmed monkeypox at home.