Methadone maintenance therapy (MMT) significantly reduces criminal behavior and recidivism according to multiple studies. Studies found crime rates reduced by 50-80% and fewer crimes committed the longer patients remained in treatment. MMT not only improved health outcomes by reducing HIV risk behaviors and mortality, but also led to dramatic declines in various criminal offenses like robbery, break-ins, and theft based on self-reports and official records. The cost savings to society from reduced criminal activity and imprisonment due to MMT were estimated to be over $55,000 per patient per year.
Appropriate Training for Police Interactions With Citizens who have Mental Il...Cynthia Micholias
This essay was written in my first year of the behavioural psychology program. I covers complex topics such as police brutality and bias, mental illness, and addiction.
Seven Days Opioid Deaths Rise in Vermont Article:
https://www.sevendaysvt.com/OffMessage/archives/2019/02/14/opioid-deaths-rise-in-vermont-but-plummet-in-chittenden-county
Authors: Martin Foureaux Koppensteinery, Jesse Mathesonz, and Réka Plugor
This working paper will be/have been presented at SITE brown bag seminar 2020-11-03. Martin Foureaux Koppensteinery have given SITE the permission to upload and share the working paper on our website and social media channels.
Appropriate Training for Police Interactions With Citizens who have Mental Il...Cynthia Micholias
This essay was written in my first year of the behavioural psychology program. I covers complex topics such as police brutality and bias, mental illness, and addiction.
Seven Days Opioid Deaths Rise in Vermont Article:
https://www.sevendaysvt.com/OffMessage/archives/2019/02/14/opioid-deaths-rise-in-vermont-but-plummet-in-chittenden-county
Authors: Martin Foureaux Koppensteinery, Jesse Mathesonz, and Réka Plugor
This working paper will be/have been presented at SITE brown bag seminar 2020-11-03. Martin Foureaux Koppensteinery have given SITE the permission to upload and share the working paper on our website and social media channels.
Opioid Addiction: New Approach Gives Hope to Patients Awaiting TreatmentSov Addiction Rehab
Amid the growing opioid crisis in the United States, the capacity of available treatment programs is falling short of demand. As a result, people needing treatment for dependency on heroin or prescription painkillers have to wait for months, sometimes even years, to get appointments with certified doctors or to find slots in rehabilitation programs.
A life course approach to preventing drugs & alcohol risks [March 2016 Int'l ...Mentor
A life-course approach to preventing drug and alcohol risks, presented at the Home Office's International Crime & Policing Conference 2016.
Presentation from Mentor CEO Michael O'Toole and Andrew Brown, formerly of DrugScope and now working with Mind and PHE.
STA 544Homework 1Work on the following problem set and show yo.docxsusanschei
STA 544
Homework 1
Work on the following problem set and show your works within the document. Use SPSS as much as possible.
Chapter 1
1. What types of activities other than “calculations” and “math” are associated with the practice of statistics?
2. Define the term measurement.
3. List the three main measurement scales addressed in this chapter.
4. What type of measurement assigns a name to each observation?
5. What type of measurement is based on categories that can be put in rank order?
6. What type of measurement assigns a numerical value that permits for meaningful mathematical operations for each observation?
7. What does GIGO stand for?
8. Provide synonyms for categorical data.
9. Provide synonyms for quantitative data.
10. What is the difference between imprecision and bias
11. How is imprecision quantified?
Chapter 2
1. Controlled-release morphine in patients with chronic cancer pain. Warfield reviewed 10 studies comparing the effectiveness of controlled-release and immediate-release morphine in cancer patients with chronic pain. The studies that were reviewed were double blinded. How would you double blind such studies?
2. What is the general goal of a statistical survey?
3. What is the general goal of a comparative statistical study?
4. What is the key distinction between experimental studies and observational studies?
5. Campus survey. A researcher conducts a survey to learn about the sexual behavior of college students on a particular campus. A list of the undergraduates at the university is used to select participants. The investigator sends out 500 surveys but only 136 are returned.
a. Consider how the low response rate could bias the results of this study.
b. Speculate on potential limitations in the quality of information the researcher will receive on questionnaires that are returned.
6. A study seeks to determine the effect of postmenopausal hormone use on mortality. What is the explanatory variable in this study? What is the response variable?
7. MRFIT. The MRFIT study discussed in an earlier illustrative example studied 12,866 high-risk men between 35 and 57 years of age. Approximately half the study subjects were randomly assigned to a special care group; the other half received their usual source of care. Death from coronary disease was monitored over the next seven or so years. Outline this study’s design in schematic form.
8. Five-City Project. The Stanford Five-City Project is a comprehensive community health education study of five moderately sized Northern California towns. Multiple-risk factor intervention strategies were randomly applied to two of the communities. The other three cities served as controls. Outline the design of this study in schematic form.
By applying factors in combination, experiments can study more than one factor at a time.
paper
by Xx xx
Submission date: 16-Mar-2020 03:51AM (UTC-0400)
Submission ID: 1276359854
File name: internationaldrugtrafficking1.docx (24.71K)
Wo.
Undocumented Immigration, Drug Problems, andDriving Under th.docxouldparis
Undocumented Immigration, Drug Problems, and
Driving Under the Influence in the United States,
1990–2014
Michael T. Light, PhD, Ty Miller, MS, and Brian C. Kelly, PhD
Objectives. To examine the influence of undocumented immigration in the United
States on 4 different metrics of drug and alcohol problems: drug arrests, drug overdose
fatalities, driving under the influence (DUI) arrests, and DUI deaths.
Methods. We combined newly developed state-level estimates of the undocumented
population between 1990 and 2014 from the Center for Migration Studies with arrest
data from the Federal Bureau of Investigation Uniform Crime Reports and fatality in-
formation from the Fatality Analysis Reporting System and the Centers for Disease
Control and Prevention Underlying Cause of Death database. We used fixed-effects
regression models to examine the longitudinal association between increased un-
documented immigration and drug problems and drunk driving.
Results. Increased undocumented immigration was significantly associated with reduc-
tions in drug arrests, drug overdose deaths, and DUI arrests, net of other factors. There was
no significant relationship between increased undocumented immigration and DUI deaths.
Conclusions. This study provides evidence that undocumented immigration has not
increased the prevalence of drug or alcohol problems, but may be associated with re-
ductions in these public health concerns. (Am J Public Health. 2017;107:1448–1454. doi:
10.2105/AJPH.2017.303884)
See also Vaughan and Galea, p. 1367.
Driving under the influence (DUI) anddrug problems remain pressing public
health issues and foci for prevention and in-
tervention efforts. Since 1990, nearly 1 mil-
lion persons in the United States have died of
drug overdoses and alcohol-related crashes.1,2
Each year, alcohol-impaired driving fatalities
account for more than one third of driving-
related deaths in the United States.3 The
economic costs of drug use and drunk driving
total more than $240 billion annually.4,5 In
addition, the rate of drug overdose fatalities
increased 137% between 2000 and 2014 and
more people died of drug overdoses in 2014
than in any previous year on record.6 These
public health trends have coincided with
a substantial influx of undocumented immi-
grants, from a population of 3.5 million in
1990 to an estimated 10.9 million in 2014,7
sparking controversy as to whether un-
documented immigration is related to the
prevalence of drug problems and DUI.8,9
Indeed, within political discourse on un-
documented immigration, public health and
safety concerns regarding drug problems and
drunk driving have received considerable
attention from public officials. In defending
Arizona’s controversial SB 1070 law, which
required law enforcement officers to de-
termine an individual’s immigration status
during a stop, in 2010, then-Governor Jan
Brewer stated “. . . the majority of the illegal
trespassers that are coming in the state of
Arizona a ...
Opioid Addiction: New Approach Gives Hope to Patients Awaiting TreatmentSov Addiction Rehab
Amid the growing opioid crisis in the United States, the capacity of available treatment programs is falling short of demand. As a result, people needing treatment for dependency on heroin or prescription painkillers have to wait for months, sometimes even years, to get appointments with certified doctors or to find slots in rehabilitation programs.
A life course approach to preventing drugs & alcohol risks [March 2016 Int'l ...Mentor
A life-course approach to preventing drug and alcohol risks, presented at the Home Office's International Crime & Policing Conference 2016.
Presentation from Mentor CEO Michael O'Toole and Andrew Brown, formerly of DrugScope and now working with Mind and PHE.
STA 544Homework 1Work on the following problem set and show yo.docxsusanschei
STA 544
Homework 1
Work on the following problem set and show your works within the document. Use SPSS as much as possible.
Chapter 1
1. What types of activities other than “calculations” and “math” are associated with the practice of statistics?
2. Define the term measurement.
3. List the three main measurement scales addressed in this chapter.
4. What type of measurement assigns a name to each observation?
5. What type of measurement is based on categories that can be put in rank order?
6. What type of measurement assigns a numerical value that permits for meaningful mathematical operations for each observation?
7. What does GIGO stand for?
8. Provide synonyms for categorical data.
9. Provide synonyms for quantitative data.
10. What is the difference between imprecision and bias
11. How is imprecision quantified?
Chapter 2
1. Controlled-release morphine in patients with chronic cancer pain. Warfield reviewed 10 studies comparing the effectiveness of controlled-release and immediate-release morphine in cancer patients with chronic pain. The studies that were reviewed were double blinded. How would you double blind such studies?
2. What is the general goal of a statistical survey?
3. What is the general goal of a comparative statistical study?
4. What is the key distinction between experimental studies and observational studies?
5. Campus survey. A researcher conducts a survey to learn about the sexual behavior of college students on a particular campus. A list of the undergraduates at the university is used to select participants. The investigator sends out 500 surveys but only 136 are returned.
a. Consider how the low response rate could bias the results of this study.
b. Speculate on potential limitations in the quality of information the researcher will receive on questionnaires that are returned.
6. A study seeks to determine the effect of postmenopausal hormone use on mortality. What is the explanatory variable in this study? What is the response variable?
7. MRFIT. The MRFIT study discussed in an earlier illustrative example studied 12,866 high-risk men between 35 and 57 years of age. Approximately half the study subjects were randomly assigned to a special care group; the other half received their usual source of care. Death from coronary disease was monitored over the next seven or so years. Outline this study’s design in schematic form.
8. Five-City Project. The Stanford Five-City Project is a comprehensive community health education study of five moderately sized Northern California towns. Multiple-risk factor intervention strategies were randomly applied to two of the communities. The other three cities served as controls. Outline the design of this study in schematic form.
By applying factors in combination, experiments can study more than one factor at a time.
paper
by Xx xx
Submission date: 16-Mar-2020 03:51AM (UTC-0400)
Submission ID: 1276359854
File name: internationaldrugtrafficking1.docx (24.71K)
Wo.
Undocumented Immigration, Drug Problems, andDriving Under th.docxouldparis
Undocumented Immigration, Drug Problems, and
Driving Under the Influence in the United States,
1990–2014
Michael T. Light, PhD, Ty Miller, MS, and Brian C. Kelly, PhD
Objectives. To examine the influence of undocumented immigration in the United
States on 4 different metrics of drug and alcohol problems: drug arrests, drug overdose
fatalities, driving under the influence (DUI) arrests, and DUI deaths.
Methods. We combined newly developed state-level estimates of the undocumented
population between 1990 and 2014 from the Center for Migration Studies with arrest
data from the Federal Bureau of Investigation Uniform Crime Reports and fatality in-
formation from the Fatality Analysis Reporting System and the Centers for Disease
Control and Prevention Underlying Cause of Death database. We used fixed-effects
regression models to examine the longitudinal association between increased un-
documented immigration and drug problems and drunk driving.
Results. Increased undocumented immigration was significantly associated with reduc-
tions in drug arrests, drug overdose deaths, and DUI arrests, net of other factors. There was
no significant relationship between increased undocumented immigration and DUI deaths.
Conclusions. This study provides evidence that undocumented immigration has not
increased the prevalence of drug or alcohol problems, but may be associated with re-
ductions in these public health concerns. (Am J Public Health. 2017;107:1448–1454. doi:
10.2105/AJPH.2017.303884)
See also Vaughan and Galea, p. 1367.
Driving under the influence (DUI) anddrug problems remain pressing public
health issues and foci for prevention and in-
tervention efforts. Since 1990, nearly 1 mil-
lion persons in the United States have died of
drug overdoses and alcohol-related crashes.1,2
Each year, alcohol-impaired driving fatalities
account for more than one third of driving-
related deaths in the United States.3 The
economic costs of drug use and drunk driving
total more than $240 billion annually.4,5 In
addition, the rate of drug overdose fatalities
increased 137% between 2000 and 2014 and
more people died of drug overdoses in 2014
than in any previous year on record.6 These
public health trends have coincided with
a substantial influx of undocumented immi-
grants, from a population of 3.5 million in
1990 to an estimated 10.9 million in 2014,7
sparking controversy as to whether un-
documented immigration is related to the
prevalence of drug problems and DUI.8,9
Indeed, within political discourse on un-
documented immigration, public health and
safety concerns regarding drug problems and
drunk driving have received considerable
attention from public officials. In defending
Arizona’s controversial SB 1070 law, which
required law enforcement officers to de-
termine an individual’s immigration status
during a stop, in 2010, then-Governor Jan
Brewer stated “. . . the majority of the illegal
trespassers that are coming in the state of
Arizona a ...
11 Sex Offenders Assessment and TreatmentShahid M. Shahidullah an.docxpaynetawnya
11 Sex Offenders: Assessment and Treatment
Shahid M. Shahidullah and Diane L. GreenINTRODUCTION
There has been a rapid growth and expansion of correctional institutions in America in the1980s and 1990s. Between 1982 and 2003, correctional expenditures for all levels of government, including federal, state, and local, increased 573 percent. In 1982, total correctional expenditures were about $9.1 billion. In 2003, they increased to about $60.9 billion (Bureau of Justice Statistics, 2006). This rapid growth in correctional expenditures was accompanied with rapid growth in incarcerated population. In 2004, there were about 7 million people in America who were in prison, or jail, or in probation. Between 1995 and 2005, the incarcerated population in America grew at an annual rate of about 3.4 percent (Bureau of Justice Statistics, 2005). In 2001, about $38.2 billion was spent by the state authorities for corrections, and out of that about $28.4 billion was spent for adult correctional facilities. In 2001, about 59 percent of the justice expenditures of the states were for corrections alone.
This growth and expansion in corrections has brought, particularly for the states, not only new prisons and prison jobs but also new responsibilities and concerns for offender management. In the context of the emerging policy model of prison reentry, correctional institutions are being increasingly asked to build a bridge between prison and communities, particularly through a model of offender management that can reduce recidivism and strengthen reentry and reintegration. A new managerial paradigm is currently growing in American corrections that emphasizes that offender management should be seen in terms of a more holistic and comprehensive perspective—a perspective that can combine risk assessment and treatment with new goals and planning for their reentry and offender management in the communities (MacKenzie, 2001). This new model has expanded particularly in the area of sex offender management, and its expansion is planned and guided nationally by the Center for Sex Offender Management [CSOM]—a federal program established in 1997 by the Office of Justice Programs, U.S. Department of Justice, in collaboration with the National Institute of Justice, National Institute of Corrections, State Justice Institute, and the American Probation and Parole Association.
The core of the CSOM model is that sex offender management must begin with effective assessment and treatment of sex offenders inside the prison. Reentry and recidivism depend on whether the risk of reoffending was effectively assessed, and suitable treatment plans were made and offered. The postincarceration success of sex offender registration, notification, tracking, and management is now seen as intimately connected with effective sex offender assessment and treatment during incarceration in prison. It is because of this emerging comprehensive approach that correctional institutions are reexamining ...
Running head DRUG TRAFFICKING 1DRUG TRAFFICKING 2.docxtodd271
Running head: DRUG TRAFFICKING 1
DRUG TRAFFICKING 2
Drug trafficking
Name
Institution
Professor
Course
Date
Lancaster, K., Hughes, C., & Ritter, A. (2017). ‘Drug dogs unleashed’: An historical and political account of drug detection dogs for street-level policing of illicit drugs in New South Wales, Australia. Australian & New Zealand Journal of Criminology, 50(3), 360-378.
The article shows the historical account which is related to the development of drug detection using dogs. Dogs were used to detect illicit drugs, and it has become one of the strategies which are used to combat drug trafficking. In political and historical context policies have been developed in addressing the issue of drug trafficking. Use of dogs is one of the strategies which is used to detect drug trafficking, and they play important roles. Drug policies help in reducing the incidences of drug trafficking and other associated impacts.
Fukumi, S. (2016). Cocaine trafficking in Latin America: EU and US policy responses. Routledge.
The article explains the role of women in drug trafficking in the USA. Most of the illicit drugs are transported by women. Historically, drug trafficking was linked to men, but nowadays women have taken a big role n distributed of the illicit drugs. The domineering role of the males made them be linked to the drugs and those who provided. Little attention was given to the role of women in drug trafficking as they were viewed as powerlessness who cannot involve in such matters. Illicit drugs such as cocaine and Heroin are smuggled by women as they are less suspected to be carrying illicit drugs.
Bagley, B. M., & Rosen, J. D. (2015). Drug trafficking, organized crime, and violence in the Americas today. University Press of Florida.
The article explains how the United States has become a consumer of illicit drugs despite efforts which have been made to combat it. Drug trafficking has become a global problem with many countries consuming illicit drugs. Policies have been implemented to control drug trafficking and reduce crimes which are related to it. Some of these policies regulate on how the victims of drug trafficking should be charged. Violence and organized crime are also linked to drug trafficking.
Broséus, J., Rhumorbarbe, D., Mireault, C., Ouellette, V., Crispino, F., & Décary-Hétu, D. (2016). Studying illicit drug trafficking on Darknet markets: structure and organization from a Canadian perspective. Forensic science international, 264, 7-14.
The article investigates Darknet markets which are used as a center for illicit drug trafficking. Online platforms are used to provide a market for illicit drugs. Technological techniques are used to ensure that the drugs reach to the buyer. Most of the illicit drug trafficking are distributed through online market until they reach the destination countries. Vendors are diversified and continue to replicate marketplaces to provide a wide range of market and come across.
Differential Effectiveness of Substance Abuse Treatment by Joyce FullerJoyce Fuller
Study considers the differential effectiveness of standard treatment for person with actual histories of drug use vs those who have been arrested for drug trafficking, possession, dealing, sales and manufacturing, with little to no evidence or report of actual drug use who were placed in drug treatment.
3Statistics in Criminal JusticeHomework 6 Each question is.docxrhetttrevannion
3
Statistics in Criminal Justice
Homework 6
Each question is worth 3 points unless otherwise noted
1. When do we use a chi square? Give an original example that is relevant to criminology or criminal justice.
2. I want to run a chi square on the variables relationship between offender and victim in an assault and whether that assault was reported to the police. Which is my independent variable and which is my dependent variable?
3. Using Chapter 17 Dataset 2, run a chi square to determine whether there is a relationship between relationship between victim and offender in an assault and whether the assault was reported to the police.
Copy and paste your output here.
Case Processing Summary
Cases
Valid
Missing
Total
N
Percent
N
Percent
N
Percent
Incident Reported To Police * Variable indicating the assailant's relationship to the victim
23003
96.0%
966
4.0%
23969
100.0%
Incident Reported To Police * Variable indicating the assailant's relationship to the victim Crosstabulation
Variable indicating the assailant's relationship to the victim
Total
stranger
slightly known
casual acquiant
well known
Incident Reported To Police
Not Reported
Count
3487
1624
2776
4721
12608
Expected Count
3529.8
1593.9
2471.4
5012.9
12608.0
% within Incident Reported To Police
27.7%
12.9%
22.0%
37.4%
100.0%
Incident Reported to Police
Count
2953
1284
1733
4425
10395
Expected Count
2910.2
1314.1
2037.6
4133.1
10395.0
% within Incident Reported To Police
28.4%
12.4%
16.7%
42.6%
100.0%
Total
Count
6440
2908
4509
9146
23003
Expected Count
6440.0
2908.0
4509.0
9146.0
23003.0
% within Incident Reported To Police
28.0%
12.6%
19.6%
39.8%
100.0%
Chi-Square Tests
Value
df
Asymptotic Significance (2-sided)
Pearson Chi-Square
123.111a
3
.000
Likelihood Ratio
123.984
3
.000
Linear-by-Linear Association
6.291
1
.012
N of Valid Cases
23003
a. 0 cells (0.0%) have expected count less than 5. The minimum expected count is 1314.12.
Questions 4-6 are based on the output you generated in Question 3.
4. What is the chi square value?
5. Is there a relationship between the variables? Or are they independent? How can you tell?
6. When is the victim least likely to report the assault to the police, when the offender is a stranger, is slightly known, a casual acquaintance, or well known? How can you tell?
7. Does the finding in Question 6 make sense to you? Why or why not?
8. When do we use a correlation? Give an original example that is relevant to criminology or criminal justice.
9. What two things does the correlation value tell us about the relationship between two variables?
10. I want to run a correlation on the variables age at first arrest and number of delinquent friends. Which is my independent variable and which is my dependent variable?
11. Using Chapter 15 Dataset 2, run a correlation to determine whether there is a relationship between age at first arrest and number of delinquent f.
Ozempic: Preoperative Management of Patients on GLP-1 Receptor Agonists Saeid Safari
Preoperative Management of Patients on GLP-1 Receptor Agonists like Ozempic and Semiglutide
ASA GUIDELINE
NYSORA Guideline
2 Case Reports of Gastric Ultrasound
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The prostate is an exocrine gland of the male mammalian reproductive system
It is a walnut-sized gland that forms part of the male reproductive system and is located in front of the rectum and just below the urinary bladder
Function is to store and secrete a clear, slightly alkaline fluid that constitutes 10-30% of the volume of the seminal fluid that along with the spermatozoa, constitutes semen
A healthy human prostate measures (4cm-vertical, by 3cm-horizontal, 2cm ant-post ).
It surrounds the urethra just below the urinary bladder. It has anterior, median, posterior and two lateral lobes
It’s work is regulated by androgens which are responsible for male sex characteristics
Generalised disease of the prostate due to hormonal derangement which leads to non malignant enlargement of the gland (increase in the number of epithelial cells and stromal tissue)to cause compression of the urethra leading to symptoms (LUTS
Report Back from SGO 2024: What’s the Latest in Cervical Cancer?bkling
Are you curious about what’s new in cervical cancer research or unsure what the findings mean? Join Dr. Emily Ko, a gynecologic oncologist at Penn Medicine, to learn about the latest updates from the Society of Gynecologic Oncology (SGO) 2024 Annual Meeting on Women’s Cancer. Dr. Ko will discuss what the research presented at the conference means for you and answer your questions about the new developments.
Couples presenting to the infertility clinic- Do they really have infertility...Sujoy Dasgupta
Dr Sujoy Dasgupta presented the study on "Couples presenting to the infertility clinic- Do they really have infertility? – The unexplored stories of non-consummation" in the 13th Congress of the Asia Pacific Initiative on Reproduction (ASPIRE 2024) at Manila on 24 May, 2024.
Recomendações da OMS sobre cuidados maternos e neonatais para uma experiência pós-natal positiva.
Em consonância com os ODS – Objetivos do Desenvolvimento Sustentável e a Estratégia Global para a Saúde das Mulheres, Crianças e Adolescentes, e aplicando uma abordagem baseada nos direitos humanos, os esforços de cuidados pós-natais devem expandir-se para além da cobertura e da simples sobrevivência, de modo a incluir cuidados de qualidade.
Estas diretrizes visam melhorar a qualidade dos cuidados pós-natais essenciais e de rotina prestados às mulheres e aos recém-nascidos, com o objetivo final de melhorar a saúde e o bem-estar materno e neonatal.
Uma “experiência pós-natal positiva” é um resultado importante para todas as mulheres que dão à luz e para os seus recém-nascidos, estabelecendo as bases para a melhoria da saúde e do bem-estar a curto e longo prazo. Uma experiência pós-natal positiva é definida como aquela em que as mulheres, pessoas que gestam, os recém-nascidos, os casais, os pais, os cuidadores e as famílias recebem informação consistente, garantia e apoio de profissionais de saúde motivados; e onde um sistema de saúde flexível e com recursos reconheça as necessidades das mulheres e dos bebês e respeite o seu contexto cultural.
Estas diretrizes consolidadas apresentam algumas recomendações novas e já bem fundamentadas sobre cuidados pós-natais de rotina para mulheres e neonatos que recebem cuidados no pós-parto em unidades de saúde ou na comunidade, independentemente dos recursos disponíveis.
É fornecido um conjunto abrangente de recomendações para cuidados durante o período puerperal, com ênfase nos cuidados essenciais que todas as mulheres e recém-nascidos devem receber, e com a devida atenção à qualidade dos cuidados; isto é, a entrega e a experiência do cuidado recebido. Estas diretrizes atualizam e ampliam as recomendações da OMS de 2014 sobre cuidados pós-natais da mãe e do recém-nascido e complementam as atuais diretrizes da OMS sobre a gestão de complicações pós-natais.
O estabelecimento da amamentação e o manejo das principais intercorrências é contemplada.
Recomendamos muito.
Vamos discutir essas recomendações no nosso curso de pós-graduação em Aleitamento no Instituto Ciclos.
Esta publicação só está disponível em inglês até o momento.
Prof. Marcus Renato de Carvalho
www.agostodourado.com
Ethanol (CH3CH2OH), or beverage alcohol, is a two-carbon alcohol
that is rapidly distributed in the body and brain. Ethanol alters many
neurochemical systems and has rewarding and addictive properties. It
is the oldest recreational drug and likely contributes to more morbidity,
mortality, and public health costs than all illicit drugs combined. The
5th edition of the Diagnostic and Statistical Manual of Mental Disorders
(DSM-5) integrates alcohol abuse and alcohol dependence into a single
disorder called alcohol use disorder (AUD), with mild, moderate,
and severe subclassifications (American Psychiatric Association, 2013).
In the DSM-5, all types of substance abuse and dependence have been
combined into a single substance use disorder (SUD) on a continuum
from mild to severe. A diagnosis of AUD requires that at least two of
the 11 DSM-5 behaviors be present within a 12-month period (mild
AUD: 2–3 criteria; moderate AUD: 4–5 criteria; severe AUD: 6–11 criteria).
The four main behavioral effects of AUD are impaired control over
drinking, negative social consequences, risky use, and altered physiological
effects (tolerance, withdrawal). This chapter presents an overview
of the prevalence and harmful consequences of AUD in the U.S.,
the systemic nature of the disease, neurocircuitry and stages of AUD,
comorbidities, fetal alcohol spectrum disorders, genetic risk factors, and
pharmacotherapies for AUD.
Explore natural remedies for syphilis treatment in Singapore. Discover alternative therapies, herbal remedies, and lifestyle changes that may complement conventional treatments. Learn about holistic approaches to managing syphilis symptoms and supporting overall health.
New Drug Discovery and Development .....NEHA GUPTA
The "New Drug Discovery and Development" process involves the identification, design, testing, and manufacturing of novel pharmaceutical compounds with the aim of introducing new and improved treatments for various medical conditions. This comprehensive endeavor encompasses various stages, including target identification, preclinical studies, clinical trials, regulatory approval, and post-market surveillance. It involves multidisciplinary collaboration among scientists, researchers, clinicians, regulatory experts, and pharmaceutical companies to bring innovative therapies to market and address unmet medical needs.
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Ve...kevinkariuki227
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
TEST BANK for Operations Management, 14th Edition by William J. Stevenson, Verified Chapters 1 - 19, Complete Newest Version.pdf
Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
1. METHADONE &
CRIMINALITY
Fifa Rahman, LLB (Hons), MHL (Health Law) (Sydney)
Policy Manager, Malaysian AIDS Council
fifarahman@outlook.com/010-2566097
2. Research & Summary of Findings
• Methadone maintenance therapy (MMT) has positive
impacts on drug-related HIV risk behaviours, mortality,
and criminality. Fullerton et al. ‘Medication-Assisted Treatment With
Methadone: Assessing the Evidence’ (2014) 65(2) Psychiatric Services 146-157
• In a study of 304 MMT patients, by self-report, crime
dropped promptly and substantially on entry to treatment,
to a level of acquisitive crime about one-eight that
reported during the last addiction period. Analysis of
official records indicated that rates of acquisitive
convictions were significantly lower in the in-treatment
period compared to prior to entry to treatment,
corroborating the changes suggested by self-report. James
Bell, ‘Methadone Maintenance and Drug-Related Crime’ (1997) 9 Journal of
Substance Abuse 15-25
3. Research & Summary of Findings (cont.)
• Data was obtained from 617 patients. The reduction in
criminality after admission to methadone maintenance
treatment was dramatic; all 14 types of crime declined
markedly - most over 80 percent. The reduction in
criminality was associated with time in treatment. J. Bali, E.
Corty, H. Bond, C. Myers and A. Tommasello, ‘The Reduction of Intravenous Heroin
Use, Non-Opiate Abuse and Crime During Methadone Maintenance Treatment: Further
Findings’ (1988) 81 NIDA Res Monogr 224-230.
• After entry to MMT, the total number of self-reported
offences declined to 50,103 crimes per year, while the
mean number of crime days per year decreased from 238
to 69. The number of crime days continued to decline with
the number of years spent in treatment. Wayne Hall, Methadone
Maintenance Treatment as a Crime Control Measure (1996) 29 Crime and Justice Bulletin, NSW
Bureau of Crime Statistics and Research
4. Research & Summary of Findings (cont.)
• …found that, for every 100 persons in methadone for one
year, New South Wales gets 12 fewer robberies, 57 fewer
break-and-enters and 56 fewer motor-vehicle thefts. Bronwyn
Lind, Shuling Chen, Don Weatherburn, and Richard Mattick, The Effectiveness Of Methadone
Maintenance Treatment In Controlling Crime: An Australian Aggregate-Level Analysis (2005) 45(2)
British Journal of Criminology 201-211
• Sixty percent of participants said they had been
committing crime daily before MMT, compared with only
1% after 57 months on MMT. There was a large reduction
in costs of crime and imprisonment to society, which was
conservatively estimated at $55,386 per drug user per
year. I Sheerin, T Green, D Sellman, S Adamson, D Deering, ‘Reduction in crime by
drug users on a methadone maintenance therapy programme in New Zealand’ (2004)
117(1190) The New Zealand Medical Journal 1-10