Metaprogramming allows programs to treat other programs as data by reading, generating, analyzing, transforming, or modifying other programs or even themselves at runtime. It has benefits like keeping code small, simple, DRY, lightweight, intuitive, and scalable. Metaprogramming techniques include macros, domain-specific languages, reflection, introspection, annotations, bytecode transformation, and abstract syntax tree manipulation. Many programming languages support metaprogramming through features like method missing, dynamic method definition, reflection, and abstract syntax tree transformations.