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Life Sciences 
Human Reproduction- Meiosis 
By Ipeleng.R.Makgaka
What is meiosis? 
• Meiosis like Mitosis is cell division 
• However meiosis is the process that converts 
diploid nuclei to a haploid nuclei. 
• In other words meiosis takes diploid body cell 
which has 46 chromosomes and converts it 
into a haploid sex cell which has 23 
chromosomes.
Where does meiosis take place? 
• Meiosis takes place in the sex organs, 
producing gametes. 
• Gametes are sex cells: sperm or eggs. 
• Gametes have to be haploid so that once 
fertilization takes the haploid sperm can fuse 
with haploid egg to form diploid zygote. 
• Therefore a zygote has a diploid number of 
chromosomes, one set from each parent
A Life cycle
Meiosis consists of... 
• Meiosis consists of two 
stages namely, Meiosis I 
and Meiosis II 
• Meiosis I consists of five 
phases namely, 
InterphaseI, ProphaseI, 
MetaphaseI, AnaphaseI, 
TelophaseI. 
• Meiosis II consists of four 
phases namely, 
ProphaseII, MetaphaseII, 
AnaphaseII, TelophaseII.
Meiosis I- Interphase I 
• The cell builds up 
energy in order for DNA 
Replication to take 
place. 
• DNA is replicated to 
make sure that 
chromosomes are 
duplicated. 
• The cell does not 
change structurally.
Meiosis I- Prophase I 
• The chromosomes coil and 
become individual 
chromosomes. 
• The nucleolus and Nuclear 
envelope begin to disappear. 
• Homologous chromosomes 
come together and exchange 
genetic information through 
the process of crossing over. 
• This will ensure genetic 
variation. 
• The Centrioli moves towards 
opposite poles with spindle 
fibres between them.
Meiosis I- Metaphase I 
• The Centrioli has 
reached the poles. 
• The homologous pairs 
align at the cell equator. 
• The two chromosomes 
attach to one spindle 
fibre by means of the 
centromere.
Meiosis I- Anaphase I 
• The Spindle Fibres begin 
to contract. 
• This causes the 
duplicated 
chromosomes to move 
towards opposite poles
Meiosis I- Telophase I 
• The duplicated 
chromosomes have 
reached the opposite 
poles. 
• A nuclear envelope and 
nucleolus begin to re-form 
around 
chromosomes. 
• Cell devides forming 2 
separate haploid cells
Meiosis II- Prophase II 
• Chromosomes coil and 
become compact if they 
uncoiled during 
Telophase I. 
• The nuclear envelope 
and nucleolus begin to 
disappear. 
• The Centrioli move to 
opposite poles, forming 
spindle fibres in 
between them.
Meiosis II- Metaphase II 
• The individual 
duplicated chromosome 
align along the equator. 
• One chromosome per 
spindle fibre are 
attached by means of 
the centromere. 
• The Centrioli has 
reached the opposite 
poles.
Meiosis II- Anaphase II 
• The spindle fibres 
contract causing 
duplicated chromosome 
to split in half. 
• These daughter 
chromosomes begin to 
move towards opposite 
poles
Meiosis II- Telophase II 
• Daughter chromosome 
reach the opposite poles. 
• The two cells invaginate 
and form four daughter 
haploid cells 
• They uncoil and form a 
chromatin network. 
• Nuclear envelope and 
nucleolus form around 
chromatin network again.
Difference between meiosis I and 
meiosis II 
Meiosis I Meiosis II 
Begins with Interphase= DNA Replication Begins with Prophase= No DNA 
replication 
Begins with Diploid number of 
chromosomes 
Begins with haploid number of 
chromosomes. 
Prophase consists of crossing over Prophase consists of no crossing over.

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Meosis

  • 1. Life Sciences Human Reproduction- Meiosis By Ipeleng.R.Makgaka
  • 2. What is meiosis? • Meiosis like Mitosis is cell division • However meiosis is the process that converts diploid nuclei to a haploid nuclei. • In other words meiosis takes diploid body cell which has 46 chromosomes and converts it into a haploid sex cell which has 23 chromosomes.
  • 3. Where does meiosis take place? • Meiosis takes place in the sex organs, producing gametes. • Gametes are sex cells: sperm or eggs. • Gametes have to be haploid so that once fertilization takes the haploid sperm can fuse with haploid egg to form diploid zygote. • Therefore a zygote has a diploid number of chromosomes, one set from each parent
  • 5. Meiosis consists of... • Meiosis consists of two stages namely, Meiosis I and Meiosis II • Meiosis I consists of five phases namely, InterphaseI, ProphaseI, MetaphaseI, AnaphaseI, TelophaseI. • Meiosis II consists of four phases namely, ProphaseII, MetaphaseII, AnaphaseII, TelophaseII.
  • 6. Meiosis I- Interphase I • The cell builds up energy in order for DNA Replication to take place. • DNA is replicated to make sure that chromosomes are duplicated. • The cell does not change structurally.
  • 7. Meiosis I- Prophase I • The chromosomes coil and become individual chromosomes. • The nucleolus and Nuclear envelope begin to disappear. • Homologous chromosomes come together and exchange genetic information through the process of crossing over. • This will ensure genetic variation. • The Centrioli moves towards opposite poles with spindle fibres between them.
  • 8. Meiosis I- Metaphase I • The Centrioli has reached the poles. • The homologous pairs align at the cell equator. • The two chromosomes attach to one spindle fibre by means of the centromere.
  • 9. Meiosis I- Anaphase I • The Spindle Fibres begin to contract. • This causes the duplicated chromosomes to move towards opposite poles
  • 10. Meiosis I- Telophase I • The duplicated chromosomes have reached the opposite poles. • A nuclear envelope and nucleolus begin to re-form around chromosomes. • Cell devides forming 2 separate haploid cells
  • 11. Meiosis II- Prophase II • Chromosomes coil and become compact if they uncoiled during Telophase I. • The nuclear envelope and nucleolus begin to disappear. • The Centrioli move to opposite poles, forming spindle fibres in between them.
  • 12. Meiosis II- Metaphase II • The individual duplicated chromosome align along the equator. • One chromosome per spindle fibre are attached by means of the centromere. • The Centrioli has reached the opposite poles.
  • 13. Meiosis II- Anaphase II • The spindle fibres contract causing duplicated chromosome to split in half. • These daughter chromosomes begin to move towards opposite poles
  • 14. Meiosis II- Telophase II • Daughter chromosome reach the opposite poles. • The two cells invaginate and form four daughter haploid cells • They uncoil and form a chromatin network. • Nuclear envelope and nucleolus form around chromatin network again.
  • 15.
  • 16. Difference between meiosis I and meiosis II Meiosis I Meiosis II Begins with Interphase= DNA Replication Begins with Prophase= No DNA replication Begins with Diploid number of chromosomes Begins with haploid number of chromosomes. Prophase consists of crossing over Prophase consists of no crossing over.