Rochester, Minnesota
   October 2009.




Helga Komen Ušljebrka , MD
    anesthesiologist
Mayo Clinic

         Rochester,
         Minnesota
         1889.

Scottsdale,
Arizona
1987.                 Jacksonville,
                         Florida
                          1986.
1883. Tornado in Rochester, MN
St. Marys Hospital, 1889.
St. Marys Hospital, 1930s.
William and Charlie Mayo


Dr. Will Mayo: ‘The best interest of the patient
            is the only interest to be considered’
Operating room, 1890s
First X-ray image on Mayo Clinic, 1897.
- 1901. First Clinic Business Manager
- 1905. L. Wilson, quick-frozen tissue
stained with methylene-blue
- 1914. Isolated thyroxin
- 1915. One of the world’s first formal
graduate training programs, many visiting
physicians
- 1920. System for grading cancer (AC
Broders)
- 1920. Basal metabolic rate (WM Boothby)
- 1934. Isolated cortisone (E. Kendall)
- 1934. First use of thiopental (JS Lundy)
- 1944. First application of streptomycin
Aero Medical Unit, 1942. (CA Lindbergh)
...developing prototype oxygen mask for pilots
Aero Medical Unit - centrifuge
- 1950. Nobel prize (Kendall and Hench)
- 1954. Methodist Hospital
- 1955. First open heart surgery (JW
Kirklin)
- 1969. Total hip replacement
- 1973. First CT scanner in North America
- 1975. Computerized system with bar
codes
- 1992. Mayo Health System – a regional
network of clinics and hospitals
- 2000. Mayo Clinic Transplant Center
- 2002. Comprehensive Cancer Center
- 2005. Electronical Medical Record
St. Marys Hospital
St. Marys Hospital
St. Marys Hospital
Plummer building, 1928.
Lobby of Plummer building
Library of Plummer building
Methodist Hospital, 1954.
Gonda building, 2001.
Lobby of Gonda building
Government

- Private group practice

- 33-member ‘Board of Trustees’-
public members, Mayo physicians and
administrators

-President and CEO of Mayo Clinic
John Noseworthy, MD, Professor of
Neurology, Interests - multiple sclerosis,
Editor-in-chief of ‘Neurology’
2008. Personnel (MN)
- 2.000 staff physicans and scientists
- 2.800 residents, fellows and students
- 28.000 health staff
- 32.800 TOTAL


Florida 4.869 total staff
Arizona 5.079 total staff
Mayo Clinic Hospitals
                     Saint Marys     Rochester
                     Hospital        Methodist
                                     Hospital
Licensed beds              1,265         794
available
Admissions/ye             43,002        18,662
ar
Operating                       55        41
rooms
Surgical                  28,071        24,421
cases/year

.......5 MILLION M2 .........
A typical day at Mayo Clinic:

Outpatient visits 5,746
Admissions to hospital 241
Surgical procedures 205

Lab tests 41.000

Radiology procedures 3.779
CT scans 647
Chest X-rays 702
MRIs 244

Units of blood components used 213
2008. Financial information

Revenue $7,222 millions
Total Assets $8,333 millions


Education and Research Funding Sources $763 m.
(Government $372 m., Benefactors $391 m.)
....Second best U.S. Hospital for 2009. (U.S.
News&World Report, July 17, 2009.)



No.1 hospital in: Digestive disorders
                  Diabetes and endocrine disorders
                  Neurology and Neurosurgery
                  Orthopaedics
Mayo Clinic Model of Care

Clinical       Research
practice




       Education
Education
                     Everyday lectures


- Clinical Case Conferences
- Core Curriculum Lectures
- Introductory Lecture Series
- Journal Clubs
- Key Word Phrase Mini-lectures
- Morbidity and Mortality Conferences
- Oral Board Reviews
- Formal practice oral examinations
- Subspecialty Mini-lectures
- Written Board Reviews

- Multidisciplinary Simulation Center

OBLIGATE! – BLS, ALS
Education
                               Evaluation


.........Monthly evaluation of trainees by supervising faculty memebers

........Quarterly each trainee meets with their faculty advisor to review
progress and goals

........Twice a year chair of Clinical Competence Committee gives
written clinical competence evaluation of trainee


.........Trainees monthly evaluate faculty and rotations


....American Board of Anesthesiology (ABA) In-Training Examination
yearly. ....nine members of Mayo’s current anesthesiology faculty
CERTIFICATION – Written and oral exam by ABA
Clinical practice
               Patient orientated




 Dr. Will Mayo: ‘The best interest of the
patient is the only interest to be considered’
Clinical practice
               Patient orientated



- Collegial staff teamwork .....’no one is big
enough to be independent of others’
- An unhurried examination
- Physicans personal responsibility for
patient care
- Comprehensive evaluation
- Availability of advanced diagnostic and
therapeutic technology
Research


- Clinical Research Units – inpatients,
outpatients, mobile facility (research vehicle)
- cca 400 projects/year
- 2800 publications a year in biomedical
journals

- Research training – clinical and laboratory
....Optional - Clinician-Investigator Program
Research

Some of projects...
- Genetic markers for intracranial aneurysms among family members
-The influence of tobacco on the extent and likelihood of proximal
progression of ulcerative colitis
-Supplemental method of controlling pain in pancreatic cancer patients
-Left ventricular-based cardiac stimulation post
AV node ablation evaluation (PAVE)
-Effectiveness of sildenafil to placebo in patients
with diastolic heart failure
-Comparison of Tacrolimus and Sirolmius
 immunosuppression in kidney transplant patients
-Memory support system for patients with amnestic
mild cognitive impairment
  ..........
                                 Impact factor 4,81
Similarities and differencies
                 Drugs

- phenylephrine vs. efedrine
- glycopirolate vs. atropin
- sucynilcoline vs. rocuronium
- Isoflurane® vs. Sevoflurane® STUDIJA
 .....propofol, fentanyl

...Drug delivery in induction by Consultant

- bupivacaine vs. levobupivacaine
Similarities and differencies
              Ventilation in OR

- anesthesia machine
     BLEASE®

- protective lung ventilation:
 6 ml/kg x f of breathing,
 etCO2 4.7-6.0 kPa, PEEP 5 kPa,
 recruitment every 1.5 hour
Similarities and differencies
          Regional anesthesia
- 2 month rotation – recovery days, OR days

- US (Sonosite® Micromax) guided blocks
- Neurostimulator guided continous blocks

- aseptic conditions
- premedication with midazolam, monitoring (SpO2,
BP cuff, ECG, temperature probe)
Similarities and differencies
          Regional anesthesia
Examples:

1. Knee replacement – sciatic block (30 ml 0,25%
bupivacaine) + femoral cont. block (test 5 ml xylo.,
bolus 20 ml 0,25% bupivacaine).......+ SAB

2. Hip replacement – psoas cont. Block (test 5 ml
xylo, bolus 25 ml 0,25% bupivacaine) + femoral cont.
block (test 5 ml xylo., bolus 20 ml 0,25%
bupivacaine).......+ SAB
Mayo Clinic Model of Care
....Obama’s Model of Care        Sept. 2009.,
 ABC News


‘.....best quality and the lowest
   cost........because of the minimized patient
   tests, fixed doctors salaries, electronic
   records and team work....’
Referring patient to Mayo Clinic

.......Anyone can request an appointment at
Mayo Clinic



Mayo Clinic’s Referring Physician Offices (24
hours a day) – tel: 800-533-1564

.....Online services
www.mayoclinic.org/medicalprofs
Collaboration with:
 J. Sprung, MD, Ph.D., prof. anesthesiology
O. Gajić, MD, Ph.D., anesthesiologist (head medical ICU)
R. Flick, MD, pediatrician, anesthesiologist (head PICU)
H. Smith, MD, anesthesiologist, regional ansthesia
B. Hoelzer, anesthesiologist , invasive pain procedures
M. Huntoon, MD, anesthesiologist, cancer pain
T. Harrison, MD, anesthesiologist (pediatric), pain clinic
J. Munis, MD, neuroanesthesiologist
E. Wijdicks, MD, Ph.D., neurologist (head ICU)
W. Nicholson, MD, clinical pharmacologist
R. White, MD, anesthesiologist, reanimatology
Art&Healing.....since 1955.




                       Ivan Meštrović,
                       ‘Man and Freedom’
                       Lobby of Gonda building
Art&Healing.....since 1955.




                         Dale Chihuly’s
                         Chandeliers,
                         Lobby of Gonda
                         building
Art&Healing.....since 1955.




                         Auguste Rodin,
                         ‘Jaine d’Aire’
                         Siebens building
Art&Healing.....since 1955.




                         Andy Warhol,
                         ‘Flowers’
Art&Healing.....since 1955.




                         Joan Miro
H Komen U, RD Miller, J Sprung
       Plummer house

                  Miller RD, Hyatt RE. Evaluation of obstructing lesions of
                  the trachea and larynx by flow-volume loops.
                  Am Rev Respir Dis. 1973 Sep;108(3):475–481.
HVALA !

Mayo Clinic - my experience

  • 1.
    Rochester, Minnesota October 2009. Helga Komen Ušljebrka , MD anesthesiologist
  • 2.
    Mayo Clinic Rochester, Minnesota 1889. Scottsdale, Arizona 1987. Jacksonville, Florida 1986.
  • 3.
    1883. Tornado inRochester, MN
  • 4.
  • 5.
  • 6.
    William and CharlieMayo Dr. Will Mayo: ‘The best interest of the patient is the only interest to be considered’
  • 7.
  • 8.
    First X-ray imageon Mayo Clinic, 1897.
  • 9.
    - 1901. FirstClinic Business Manager - 1905. L. Wilson, quick-frozen tissue stained with methylene-blue - 1914. Isolated thyroxin - 1915. One of the world’s first formal graduate training programs, many visiting physicians - 1920. System for grading cancer (AC Broders) - 1920. Basal metabolic rate (WM Boothby) - 1934. Isolated cortisone (E. Kendall) - 1934. First use of thiopental (JS Lundy) - 1944. First application of streptomycin
  • 10.
    Aero Medical Unit,1942. (CA Lindbergh) ...developing prototype oxygen mask for pilots
  • 11.
    Aero Medical Unit- centrifuge
  • 12.
    - 1950. Nobelprize (Kendall and Hench) - 1954. Methodist Hospital - 1955. First open heart surgery (JW Kirklin) - 1969. Total hip replacement - 1973. First CT scanner in North America - 1975. Computerized system with bar codes - 1992. Mayo Health System – a regional network of clinics and hospitals - 2000. Mayo Clinic Transplant Center - 2002. Comprehensive Cancer Center - 2005. Electronical Medical Record
  • 14.
  • 15.
  • 16.
  • 17.
  • 18.
  • 19.
  • 20.
  • 21.
  • 22.
  • 23.
    Government - Private grouppractice - 33-member ‘Board of Trustees’- public members, Mayo physicians and administrators -President and CEO of Mayo Clinic John Noseworthy, MD, Professor of Neurology, Interests - multiple sclerosis, Editor-in-chief of ‘Neurology’
  • 24.
    2008. Personnel (MN) -2.000 staff physicans and scientists - 2.800 residents, fellows and students - 28.000 health staff - 32.800 TOTAL Florida 4.869 total staff Arizona 5.079 total staff
  • 25.
    Mayo Clinic Hospitals Saint Marys Rochester Hospital Methodist Hospital Licensed beds 1,265 794 available Admissions/ye 43,002 18,662 ar Operating 55 41 rooms Surgical 28,071 24,421 cases/year .......5 MILLION M2 .........
  • 26.
    A typical dayat Mayo Clinic: Outpatient visits 5,746 Admissions to hospital 241 Surgical procedures 205 Lab tests 41.000 Radiology procedures 3.779 CT scans 647 Chest X-rays 702 MRIs 244 Units of blood components used 213
  • 27.
    2008. Financial information Revenue$7,222 millions Total Assets $8,333 millions Education and Research Funding Sources $763 m. (Government $372 m., Benefactors $391 m.)
  • 28.
    ....Second best U.S.Hospital for 2009. (U.S. News&World Report, July 17, 2009.) No.1 hospital in: Digestive disorders Diabetes and endocrine disorders Neurology and Neurosurgery Orthopaedics
  • 29.
    Mayo Clinic Modelof Care Clinical Research practice Education
  • 30.
    Education Everyday lectures - Clinical Case Conferences - Core Curriculum Lectures - Introductory Lecture Series - Journal Clubs - Key Word Phrase Mini-lectures - Morbidity and Mortality Conferences - Oral Board Reviews - Formal practice oral examinations - Subspecialty Mini-lectures - Written Board Reviews - Multidisciplinary Simulation Center OBLIGATE! – BLS, ALS
  • 31.
    Education Evaluation .........Monthly evaluation of trainees by supervising faculty memebers ........Quarterly each trainee meets with their faculty advisor to review progress and goals ........Twice a year chair of Clinical Competence Committee gives written clinical competence evaluation of trainee .........Trainees monthly evaluate faculty and rotations ....American Board of Anesthesiology (ABA) In-Training Examination yearly. ....nine members of Mayo’s current anesthesiology faculty CERTIFICATION – Written and oral exam by ABA
  • 32.
    Clinical practice Patient orientated Dr. Will Mayo: ‘The best interest of the patient is the only interest to be considered’
  • 33.
    Clinical practice Patient orientated - Collegial staff teamwork .....’no one is big enough to be independent of others’ - An unhurried examination - Physicans personal responsibility for patient care - Comprehensive evaluation - Availability of advanced diagnostic and therapeutic technology
  • 34.
    Research - Clinical ResearchUnits – inpatients, outpatients, mobile facility (research vehicle) - cca 400 projects/year - 2800 publications a year in biomedical journals - Research training – clinical and laboratory ....Optional - Clinician-Investigator Program
  • 35.
    Research Some of projects... -Genetic markers for intracranial aneurysms among family members -The influence of tobacco on the extent and likelihood of proximal progression of ulcerative colitis -Supplemental method of controlling pain in pancreatic cancer patients -Left ventricular-based cardiac stimulation post AV node ablation evaluation (PAVE) -Effectiveness of sildenafil to placebo in patients with diastolic heart failure -Comparison of Tacrolimus and Sirolmius immunosuppression in kidney transplant patients -Memory support system for patients with amnestic mild cognitive impairment .......... Impact factor 4,81
  • 36.
    Similarities and differencies Drugs - phenylephrine vs. efedrine - glycopirolate vs. atropin - sucynilcoline vs. rocuronium - Isoflurane® vs. Sevoflurane® STUDIJA .....propofol, fentanyl ...Drug delivery in induction by Consultant - bupivacaine vs. levobupivacaine
  • 37.
    Similarities and differencies Ventilation in OR - anesthesia machine BLEASE® - protective lung ventilation: 6 ml/kg x f of breathing, etCO2 4.7-6.0 kPa, PEEP 5 kPa, recruitment every 1.5 hour
  • 38.
    Similarities and differencies Regional anesthesia - 2 month rotation – recovery days, OR days - US (Sonosite® Micromax) guided blocks - Neurostimulator guided continous blocks - aseptic conditions - premedication with midazolam, monitoring (SpO2, BP cuff, ECG, temperature probe)
  • 39.
    Similarities and differencies Regional anesthesia Examples: 1. Knee replacement – sciatic block (30 ml 0,25% bupivacaine) + femoral cont. block (test 5 ml xylo., bolus 20 ml 0,25% bupivacaine).......+ SAB 2. Hip replacement – psoas cont. Block (test 5 ml xylo, bolus 25 ml 0,25% bupivacaine) + femoral cont. block (test 5 ml xylo., bolus 20 ml 0,25% bupivacaine).......+ SAB
  • 40.
    Mayo Clinic Modelof Care ....Obama’s Model of Care Sept. 2009., ABC News ‘.....best quality and the lowest cost........because of the minimized patient tests, fixed doctors salaries, electronic records and team work....’
  • 41.
    Referring patient toMayo Clinic .......Anyone can request an appointment at Mayo Clinic Mayo Clinic’s Referring Physician Offices (24 hours a day) – tel: 800-533-1564 .....Online services www.mayoclinic.org/medicalprofs
  • 42.
    Collaboration with: J.Sprung, MD, Ph.D., prof. anesthesiology O. Gajić, MD, Ph.D., anesthesiologist (head medical ICU) R. Flick, MD, pediatrician, anesthesiologist (head PICU) H. Smith, MD, anesthesiologist, regional ansthesia B. Hoelzer, anesthesiologist , invasive pain procedures M. Huntoon, MD, anesthesiologist, cancer pain T. Harrison, MD, anesthesiologist (pediatric), pain clinic J. Munis, MD, neuroanesthesiologist E. Wijdicks, MD, Ph.D., neurologist (head ICU) W. Nicholson, MD, clinical pharmacologist R. White, MD, anesthesiologist, reanimatology
  • 43.
    Art&Healing.....since 1955. Ivan Meštrović, ‘Man and Freedom’ Lobby of Gonda building
  • 44.
    Art&Healing.....since 1955. Dale Chihuly’s Chandeliers, Lobby of Gonda building
  • 45.
    Art&Healing.....since 1955. Auguste Rodin, ‘Jaine d’Aire’ Siebens building
  • 46.
    Art&Healing.....since 1955. Andy Warhol, ‘Flowers’
  • 47.
  • 48.
    H Komen U,RD Miller, J Sprung Plummer house Miller RD, Hyatt RE. Evaluation of obstructing lesions of the trachea and larynx by flow-volume loops. Am Rev Respir Dis. 1973 Sep;108(3):475–481.
  • 49.