Parasitology - Mansonella perstans

1. MANSONELLA
PERSTANS

2. GD: Tropical Africa, Central and Eastern
South America, Central America &
Caribbean.
Pathogenesis: Mansonellosis
Habitat: Body Cavities (peritoneal cavity
or pleural cavity)
Vector: Culicoides sp. (female/biting
midges)
EPIDEMIOLOGY

3. MORPHOLOGY
 Microfilaria
 200 μm in length; width of 4.5 μm; have the
ability to elongate and contract (can vary in
measurement and form)
 unsheathed
 nuclei extend to the end of the blunt tail
 head spot sometimes has a V-shaped
appearance
 Adult
 white and thread-like
 cylindrical in shape
 Male
 45 mm by 60 μm; tail is full coil
 Female

4. LIFE CYCLE

5. MANIFESTATION
 often asymptomatic (no symptoms
shown)
 associated with angioedema, pruritus,
fever, headaches, arthralgias, and
neurologic manifestations.
 eosinophilia, headache, fever, or
abdominal pain may also be present
 nodules in conjunctiva (kampala or
Ugandan eye worm)

6.  microscopic examination
 blood samples
 antigen detection
DIAGNOSIS
TREATMENT
 albendazole and mebendazole
 combination treatments of diethylcarbamazine and
mebendazole
 doxycycline