In the presentation, Anthony J. Scriffignano discusses the challenges posed by the overwhelming volume of data and the need for new decision-making frameworks in a rapidly evolving data landscape. Key issues include understanding the implications of data saturation, the necessity for advanced analytical skills, and the importance of adapting to changes in data relevance and veracity. The talk emphasizes critical thinking, situational awareness, and innovative methodologies to harness big data effectively while addressing emerging threats and opportunities.