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Medical Linear Accelerators
Dr Rajesh Kumar
RPAD BARC
Radiation Therapy
External Beam Therapy or
Teletherapy
BrachyTherapy or
Endocurie Therapy
Nuclear Medicine
Co-60
Mega Voltage therapy
Electron
X-Ray Beam Therapy
Grenz-Ray Therapy
Contact Therapy
Superficial Therapy
Medium Voltage Therapy
Deep Therapy
Soft x-ray below 20KV, low penetrating power,
Operate at potential 40-50 KV, very short distance
treatment, treatment depth not more than 1-2 mm
Operate at potential ranging from 50-150 KV, treatment
distance 15-20 cm, useful for tumors confined to about
5mm depth.
Operate at potential ranging from 200-
300 KV, treatment distance 50 cm
Operate at potential ranging from 150-200 KV
Grenz-therapy machine
Deep therapy
X-ray Machine
Superficial Therapy X-Ray Machine
Different applicators and filters
Orthovoltage (deep) x-ray equipment
Grenz
super
Ortho
contact
Co-60
Skin sparing effect: low surface dose compared to maximum dose
Limitations of Low Energy Machines
Can not reach deep-seated tumors
with an adequate dosage of
radiation.
Do not spare skin and normal
tissues.
•Photon Beam (X-Ray):
•4 MV To 22 MV.
•Single Beam.
•Dual Beams
•Electron Beam:
•Multi-Beams with
energy group between:
4- 22 MeV.
What is a Linear Accelerator?
•Treatment machine that uses high-frequency
electromagnetic waves to accelerate charged
particles such as electrons to high energies via a
linear tube.
Charged particles travel in straight lines as they gain
energy from an alternating electromagnetic field.
• The resonating cavity frequency of the medical linacs
is about 3 billion Hertz (cycles/sec) .
• This is the most common device to treat cancer with
external beam radiation.
How does it work?
• The linear accelerator (Linac),
uses microwave technology to
accelerate electrons in a part of
the linac called waveguide, then
allows these electrons to collide
with a heavy metal target. As a
result of these collisions, high
energy X-‐Rays (Photons) are
produced from the target.
How does it work?
• These high energy photons will be
directed to the patient’s tumor and
shaped as they exit the linac to
conform to the shape of the tumor.
• Radiation can be delivered to the
tumor from any angle by rotating
the gantry and moving the
treatment couch.
Early Accelerators
The first one was installed at
Hammersmith in 1952.
In 1956, the first patient was
treated at Stanford
University in the United
States.
The Linac had an 8 MV X-‐ray
beam with limited gantry
motion.
These linacs were large and
bulky.
2nd Generation Linacs
• The second generation,
were isocentric units,
which can rotate 360
degrees around the
gantry axis.
• They were built between
1962 and 1982.
• They improved in
precision and accuracy of
dose delivery.
3rd Generation Linacs
• Better accelerator
waveguides and
bending magnet
systems and more
beam modifying
accessories.
• Wider range of beam
energies, dose rates,
field sizes and
operating modes.
• Higher reliability and
computer driven.
Components
1.Gantry
2.Gantry/Drive stand
3.Modulator cabinet
4.Patient Support
Assembly (PSA)
5.Control Console
Major Components of a LINAC
1) Electron injection system
2) RF power generator
3) Accelerating waveguide
4) Auxiliary system
5) Beam transport system
6) Beam collimation system, and
7) Beam monitoring system
Main Beam Forming Components
Drive Stand
Drive Stand: a stand containing the apparatus that
drives the linear accelerator
Open on both sides with swinging doors for easy access to
gauges, valves, tanks, and buttons
Klystron/Magnetron: power source used to generate
electromagnetic waves for the accelerator guides
Waveguide: hollow tube-like structure that guide the
electromagnetic waves from the magnetron to the
accelerating guide where electrons are accelerated
Circulator: directs the RF energy into the waveguide and
prevents any reflected microwaves from returning to the
klystron
Water-cooling system: allows many components in the gantry
and drive stand to operate at a constant temperature
The Klystron
• Provides the
source of
microwave
power to
accelerate the
electrons.
• This is done by
amplifying
introduced Radio
Frequency (RF)
electromagnetic
waves.
The Magnetron
• Electron tube that
provides microwave
power to accelerate
the electrons.
• Preferred for lower
electron energies, 4
MeV to 6 MeV linacs.
• For higher energies
the Klystron is a better
choice.
Electron Gun
Electrons produced by thermionic emission
Accelerator Guide
• This is sometimes called the accelerator structure
or accelerator wave guide.
• It can be mounted in the gantry horizontally for
high energy single or dual energy machines with
klystrons.
• Can be mounted vertically for low energy
machines with magnetrons.
• The microwave power produced in the klystron
or magnetron is transported to the accelerator
structure to accelerate the pulsed electron
bunches.
Components of Medical LINACs
Linac: Configurations
LINAC Head: Varian
LINAC Head: Siemens
LINAC Head: Elekta
Gantry: responsible for
directing the photon (x-
ray) energy or electron
beam at a patients
tumor.
Electron gun: produce electrons and injects them into
the accelerator structure
Accelerator structure: a special type of wave guide in
which electrons are accelerated.
Treatment head: components designed to shape and
monitor the treatment beam
Pulse Forming Network:
• A pulse forming network (PFN) is an
electric circuit that accumulates electrical
energy over a comparatively long time,
then releases the stored energy in the
form of a relatively square pulse of
comparatively brief duration for various
pulsed power applications.
• The Thyratron uses these pulses as a high-‐tech
switch to deliver these pulses to the electron
gun.
Treatment Head:
Treatment head: components
designed to shape and monitor
the treatment beam
Bending magnet: direct the electrons
vertically toward the patient
X-ray target, Primary collimator:
designed to limit the maximum field
size, Beam flattening filter: shaped the
x-ray beam in its cross sectional
dimension, Ion chamber: monitors the
beam for its symmetry in the right-left
and inferior-superior direction,
Secondary collimators: upper and
lower collimator jaws, Field light:
outlines the dimensions of the
radiation field as it appears on the
patient, allows accurate positioning of
the radiation field in relationship to
skim marks or other reference points
Modulator Cabinet:
• Modulator cabinet:
contains components that
distribute and monitor
primary electrical power
and high-voltage pulses to
the magnetron or klystron
• This is the noisiest of the
linac system components
and is located inside the
treatment room.
• Contains 3 subcomponents:
• Fan Control, cooling the
power distribution system.
• The auxiliary power
distribution system, contains
the emergency off button
that shuts the power to the
linac.
• Primary power distribution
system.
Bending Magnet:
• Changes the direction of
the electron beam,
downwards toward the
patient.
• Bends the pulsed electron
beam towards the target
for X-‐raysor toward the
scattering foil for electron
treatments.
• Produces different beam
paths for different
energies.
• Needed for energies
greater than 6 MeV.
Bending Magnet
Bending magnet: bends the electron beam through a
right angle, so it ends up pointed at the patient
90 degree magnets (chromatic) have the property that any
energy spread results in spatial dispersion of the beam.
Electrons are bent in proportion with their energy, the lower
energy electrons are bent more, the higher energy electrons
less
Results in a beam that is spread from side to side according
to energy
Energy sensitive, act as energy differentiators
270 degree magnets (achromatic) designed to eliminate
spatial dispersion
So not significantly disperse the different electron energies
in the beam.
90 Bending of electron beam
Achromatic Bending
Varian: 3x90
Siemens
112.5 Slalom Bending (Elekta)
X-‐RayTarget:
• The collision of the electrons with the high
density transmission target creates the X-‐Rays
(photons), forming a forward peaking shaped
X-‐raybeam in the direction of the patient’s
tumor.
• The X-‐raytarget is located at the focus of the
Bending Magnet.
• 94% of the electrons energy goes into heat.
Linac: components
Electron
Gun
Target
Cut-away view of a standing
wave accelerating
waveguide for a 6 MV linac.
The accelerating cavities are
on the central axis, the
coupling cavities are off-
side.
The Water Cooling System
Located in the Drive Stand and Gantry
• Provides thermal stability
to the system.
• Allows many components
in the Drive Stand and
Gantry to operate at a
constanttemperature.
Beam Flattening Filter:
• It is a conical shaped metal absorber, that
absorbs more forward peaking photons than the
ones in the periphery.
• Shapes the X-‐rays in their cross sectionalshape.
• It is required to create a flattened beam of
sufficient area, uniformity and symmetry.
• It is usually made of Tungsten, Steel, Lead,
Uranium and Aluminum.
• In dual energy photon linacs, two flattening filters
are required for the low and the higher photon
energies.
Scattering Foils:
• The electron beams have pencil-‐like shapes.
• These narrow pencil beams need to be
broadened to clinical useful beams and need to
be made uniform.
• There is a different scattering foil for each
electron beam energy produced.
• Made out of Aluminum or Cooper.
• A thin foil (or multiple ones)are used, they are
measured in mils, i.e. 8 mils of Al is about 0.2
millimeters.
Carousel in Standard LINAC
Carousel
Monitor Ionization Chambers:
• They monitor integrated Dose, Dose Rate and
Field Symmetry.
• The radiation that leaves the X-‐RayTarget or
the electron Scattering Foils will pass through
dual monitor ionization chambers, and they
produce an ionization current.
• This ionization current is proportional to the
X-‐ray of electron beamintensity.
Linac: Alignment of electron beam to target
Linac: Electron beam steering
Collimators:
• The radiation beams are collimated by
adjusting the upper and lower collimator jaws.
• The jaws are made of High Z number, like
Tungsten or Lead.
• The jaws can define a rectangular shaped
beam up to 40 cm by 40 cm for X-‐raybeams.
Treatment Couch:
• The treatment couch
or table is where the
patient lays still to
receive the radiation
treatment.
• It moves Up/Down,
Right/Left and In/
Out.
• Robotic couches are
being used in some
linacs nowadays for
3 more degrees of
freedom.
Medical Linac
46
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Electron gun
Accelerator
Wave guide
Target
Bending
magnet
Carrousel with
fla]ening filters
and foils
Transmission
Ion Chambers
MLC’s
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Electron beam
accelerated in
wave guide
Forward peaked X-‐ray
beam
X-‐RayTarget
Flattening
Filter
Electron
scattering foil
Secondary
Collimator jaws
X-‐rayBeam
central axis
Accessory Holder
Slot
Electron Beam path
Accelerated
electronbeam
X-‐ray targetremoved
Scattering Foil
Transmission
monitor ion
chambers
Accessory Mount
Electron Beam Central Axis Electron cone or
applicator
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Electron gun
Accelerator
Wave guide
Target
Bending
magnet
Carrousel with
fla]ening filters
and foils
Transmission
Ion Chambers
MLC’s
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Multi Leaf Collimators (MLC’s)
• They are heavy metal field-‐shapingdevices
with independent moving mechanisms used
to create a custom like block to spare normal
tissue and direct the radiation dose to the
tumor.
• The MLC’s became a key element in the
treatment delivery of X-‐raybeams with IMRT
(Intensity Modulated Radiation Therapy).
Journey of Radiotherapy Technology
Radiation field created using MLCs
Siemens
Varian
Elekta
Availability of MLC
MLCs are available from all the major
medical LINAC manufacturers :
Elekta
Siemens
Varian
Independent manufacturers:
BrainLab
Radionics
Direx
NOMOS
Novalis
MLC
Conventional
Secondary Tertiary
Singly Focused
Doubly Focused
OR
Mini Micro
Single Plane
Double Plane
OR
Miniature
MLC: basic information
RPT_72 AAPM TG50: terminology
Leaf width: small leaf dimension
perpendicular to the motion direction
(and to propagation direction)
Leaf length: leaf dimension parallel to
the motion direction (and to
propagation direction)
Leaf end: the surface of the
leaf inserted into the field along
this dimension
Leaf side: the surfaces in contact with
adjacent leaves
Height of the leaf: the dimension of
the leaf along the direction of
propagation of the primary x-ray beam
(from the top of the leaf near the x-
ray
source to the bottom of the leaf nearest
the isocenter (attenuation properties)
RPT_72 AAPM TG50: transmission
Leaf transmission: the reduction of
dose through the full height of the leaf
Interleaf transmission: the reduction of
dose measured along a line passing
between leaf sides
End transmission: the reduction of
dose measured along a ray passing
between the ends of opposed leaves in
their most closed position
MLC transmission: the average of leaf
and interleaf transmissions (should be
less than 2%) TPS parameter
MLC - leaf end shape
MLC – leafside: The Tongue and Groove
a tongue-and-
on is divided
f the two
• To reduce
groove des
• If a large f
into two s
treatment f
the interleaf leakage some MLCs are using
ign
ield perpendicular to the leaf motion directi
ubfields, an underdosage at the matchline o
ields is observed (IMRT, VMAT)
Huq et al., PMB 47, 2002
MLC – motion
constraints
Leaf over-travel: the maximum distance
over the beam CAX to which an MLC leaf can travel
Leaf span: the maximum distance from the tip of the
most retracted leaf to the tip of the most extended leaf
MLC - The Interdigitation
• It is the ability of leaves on one side of a field to interdigitate with
neighboring leaves on the opposing leaf bank
• The ends of odd-numbered leaves from the right-hand bank are
driven past the ends of even- numbered leaves from the left-hand
bank
• The Varian collimator was the first commercial system that could
perform it
MLC configuration in the
Treatment Head
MLC – Varian configuration
Terziary, 3rd level (or Add-on) Collimator
HEAD ASSEMBLY of Elekta LINAC
The upper jaw (Y) is
replaced by the MLC
leaves and a back-up
diaphragm (Y-back) placed
beneath the leaves follows
the leaves to provide
additional
attenuation.
ELEKTA MLC: Y-Jaw replacement
No. of leaves 80
Material Tungsten
Thickness (height) 7.5 cm
Arrangement Tongue and Groove
Width at isocentre 1.0 cm
Movement path Linear
End design Curved/rounded
Focusing Single
Interdigitization of opposite leaves Possible
Position Sensor Optical/CCD camera
Back-up jaw thickness 3.0 cm
Field size at isocentre 40 x 40 cm2
MLC – Elekta configuration
Upper Jaw replacement
MLC
Agility
MLC – Elekta design (1)
• MLC closest to source
• Rounded leaf-end Single focused
• The MLC leaves move in the y-direction
……………………………………………………………………….
• Backup collimator moving with MLCs
• A “back-up” collimator, located beneath the leaves and above the
lower jaws, augments the attenuation provided by the individual leaves
• The back-up is essentially a thin upper jaw that can be set to follow the
leaves if they are being ganged together to form a straight edge or else
set to the position of the outermost leaf if the leaves are forming a
shape
MLC – Elekta design (2)
• The primary advantage of the upper jaw replacement design is that the
range of motion of the leaves required to traverse the collimated field
width is smaller, allowing for a shorter leaf length and therefore a
more compact treatment head diameter
………………………………………………………………………..
• The disadvantage of having the MLC leaves so far from the
accelerator isocenter is that the leaf width must be somewhat smaller
and the tolerances on the dimensions of the leaves as well as the leaf
travel must be tighter than for other configurations.
The ELEKTA MLCs
Agili
ty™
Beam
ModulatorT
M
MLCi
2™
Ape
xTM
MLci2TM
MLCi2™
Width leaf (@iso) 10 mm
Number of leaves 80 (40 pairs)
Max field size (@iso) 40 cm x 40 cm
Over-travel 12.5 cm
Focalized single
Thickness 8.2 cm
Interdigitation yes
Penumbra < 7 mm (5 cm x 5
cm to 15 cm x 15
cm)
< 8 mm (> 15 cm x
15 cm)
RT delivery 3DCRT-IMRT-VMAT
MLC Elekta Beam Modulator™
Beam
Modulator™
Width leaf (@iso) 4 mm
Number of leaves 80 (40 pairs)
Max field size (@iso) 16 cm x 21 cm
Over-travel full
Focalized single
Thickness 7.5 cm
Interdigitation yes
Back-up collimator no
Penumbra < 4 mm (up to 5 cm
x 5 cm)
< 5 mm (up to 10 cm
x 10 cm)
< 6 mm (> 10 cm x
10 cm)
RT delivery 3DCRT-IMRT-VMAT
µMLC Elekta Apex™
Apex™ (add-on)
Width leaf (@iso) 2.5 mm
Number of leaves 112 (56 pairs)
Max field size (@iso) 12 cm x 14 cm
Over-travel ¾ field size
Focalized double
Thickness 8 cm
Interdigitation yes
Junction Tongue and groove
Penumbra < 3.5 mm
RT delivery 3DCRT-IMRT-S&S
no VMAT
MLC – the new Elekta configuration:
complete upper replacement
(opposite of Siemens design)
The Elekta MLC AgilityTM
• Number of leaves: 160
• Interdigitation: yes
• Material: W-alloy leaves
• Width (@ isocentre): 5 mm
• The leaves are mounted on dynamic leaf guides
that can move up to 15 cm; relative to the guide
the leaves can extend up to 20 cm
• Leaf sides: flat
• The gaps between the leaves: tilted to reduce overall transmission
• The single pair of diaphragms are a novel, sculpted design to reduce
their thickness where leaves will always provide additional shielding
They move perpendicular to the MLC and can over-travel the central
axis by up to 12 cm; both the leaf and diaphragm ends arerounded.
AgilityTM
Elekta MLCs
comparison
Leaves shift
towards the
region with
minor leakage
AgilityTM
AgilityTM
MLC – Varian configuration
• It is positioned just below the level of the standard upper and lower
jaws
• This is “ok” for maintenance actions
• Disadvantage: the added bulk and the minor clearance to the
mechanical isocenter
• Moving the MLC farther from the x-ray target requires an increase in
the size of the leaves and a longer travel distance to move from one
side of the field to the other
• The result is that such a tertiary system decreases the collision free
zone
• In IMRT, to cover large fields, it can become necessary to split the
field in 2 or 3 sub-fields (different carriage positions)
Clearance head
MLC Largest Block tray Wedge
Elekta 45 cm 35.3 cm 35.3 cm
Siemens 43 cm 43 cm 43 cm
Varian 42 cm 35 cm 35 cm
MLC – Varian design
• Rounded leaf-end
• Single focused
• No backup jaw moving with MLCs
MLC – Varian Millenium120TM
o The leaves travel on a carriage to extend their
movement across the field
o Leaf interdigitation: yes
o The distance between the most extended
leaf and the most retracted leaf on the same
side (carriage) can be up to 15 cm
o Max field length X-direction: 40 cm
o Max leaf retract position (from CAX): 20.1
cm
o Max leaf extend position (over CAX): -20cm
o Leaf width in the central 20 cm of field: 5
mm
o Leaf width in outer 20 cm of field: 10 mm
o Maximum speed: 2.5 cm/s
o Leaf height: 60 mm
o Leaf end radius: 80 mm
o Leaf tongue and groove offsets: 0.4mm
o W-alloy
Leaf motion
constraints
VARIAN Millenium120TM
Extending the leaves out to the field center is not possible
when large fields are used. This can be illustrated by a medium
field size of 20-cm width that is symmetric relative to the field
center. Here, the entire carriage can be moved so that the
leaves can extend 5 cm (the 15 cm limit minus the 10 cm half
field width) over the field center
MLC – Varian 2.5 mm HD120TM
• The width of the central leaves is 2.5mm
• Each side of the Varian collimator is configured with 60 leaves distributed in an 8
cm wide central region with 32x2.5 mm leaves, flanked by two 7 cm wide outer
regions with 14x5.0 mm leaves, for a total width of 22cm
• Maximum static field size: 40 x 22 cm2
• MLC mounted on Varian True BeamTM True BeamSTx
TM
MLC –
Siemens
configuration
Lower Jaw replacement
Siemens MLC
All the leaves are
independently controlled.
The leaves may be manually
positioned with an MLC hand
control.
Leaf settings can be uploaded
to an information
management Record and
Verify (R&V) system.
End-on view of the Siemens MLC
truncated pie shape of the leaves as well as the leaf side
shape to reduce interleaf transmission
SIEMENS MLC:X-Jaw Replacement
No. of leaves 58
Field size at isocentre 40 x 40 cm2
Material Tungsten
Thickness (height) 7.6 cm
Arrangement Tongue and Groove
Width at isocentre 1.0 cm – inner 27 pairs
6.5 cm – outer 2 pairs
Movement path Circular arc
End design Straight
Focusing Double
Interdigitization Not Possible
Position Sensor Linear encoders
•Double focused (Conic geometry)
•Lower leakage
•Minimized penumbra independent of leave
position
•Flat edges (no rounded edges)
•No gap between closed leaves
•No carriage (no IMRT segmentation in 2
fields
Siemens
MLC – Siemens design
• MLC replaces completely secondary collimator
• The leaf ends are straight and are focused on the x-raysource
• The leaf ends as well as the leaf sides match the beam divergence,
making the configuration double-focused
• Y-jaw backups each MLC segment
Siemens MLC leaf ends
Siemens linacs use MLCs that move in an arc
such that the flat faces of the leaf ends are
always in the same plane as the radiation focus
Siemens 160 MLCTM
Outline
 PATIENT SUPPORT
TREATMENT COUCH
Patient-support
• Patient support and positioning devices are designed to
implement a given treatment technique
• Important criteria include patient comfort, stability, and
reproducibility of set-up and treatment geometry that allows
accurate calculation and delivery of dose
Treatment couch - movements
4 degrees of movements: vertical, transversal, longitudinal, yaw
6 degrees movements: vertical, transversal, longitudinal, yaw, pitch, roll
(with remote robotic control capability)
Treatment couch - rotations
• PITCH: rotation around
the X-axis
• ROLL: rotation around the
Y-axis
• YAW: rotation around the
Z-axis
Treatment couch - tabletop
• Current linac couch has special top consisting in a carbon
fiber table
• The carbon fiber plates sandwiched with a plastic foam core
• The carbon fiber construction ensures that no metal parts
are used in the entire treatment area
Seppala, Kulmala, J App Cl Med Phys 12(4), Fall 2011
Elekta HexaPOD™ evo (6 DOF)
baseboard
Connexion Short
Indexing Bar
IGRT
module
Varian Exact™
IGRT
(4 DOF)
Varian PerfectPitchTM
(6 DOF)
Maximum pitch and roll is ± 3.0 degrees
HEAD ASSEMBLY OF VARIAN LINAC
VARIAN MLC: Tertiary
Material Tungsten
Thickness (height) 5.0 cm
Arrangement Tongue and Groove
Movement path Linear
End design Curved/rounded
Focusing Single
Interdigitization Possible
Position Sensor Linear encoders
Standard
Millennium
HDMLC
Design of Varian Millennium MLC
Comparatively less
Out-of-field leakage
Varian MLCs
-----------------------------------------------------------------------------------
Model No. Leaves Field Size Leaf widths
@ Isocenter
-----------------------------------------------------------------------------------------------------
Millennium MLC-52 52 26 x 40 cm2 10 mm
Millennium MLC-80 80 40 x 40 cm2 10 mm
Millennium MLC-120 120 40 x 40 cm2 Centre: 5 mm, 40 pairs
Periphery: 10 mm, 20 pairs
HDMLC 120 40 x 22 cm2 Centre: 2.5 mm, 32 pairs
Periphery: 5 mm, 28 pairs
BrainLAB-m3 52 10 x 10 cm2 3.0 mm, 4.5 mm,
and 5.5 mm
-----------------------------------------------------------------------------------------------------
Leaf Material: Tungsten Alloys
Comparison of leaf assembly
(End-on view)
Elekta Varian Siemens
A comparison of
leaf over travel
configurations
Direx Acculeaf: Four Bank mMLC
BEV of AccuLeaf
aperture showing both
levels
AccuSoft BEV with
Digitally
Reconstructed
Radiographs (DRR)
using AccuLeaf
AccuLeaf - Specifications
Number of leaves 96 leaves (4 banks in perp. orientation)
Clearance ~ 300 mm LINAC dependent
Leaf material Wolfram (high grade)
Leaf height set in two levels, 38 mm each (total 76 mm)
Leaf width - 14 inner leaves ~3.1 mm at isocentre
at isocentre ~2.6 mm effective
- 10 outer leaves ~5.3 mm at isocentre
Field size at isocentre ~ 100 x 110 mm
Max. leaf travel at isocentre ~93 mm
Max. leaf over travel at isocentre ~ 33 mm
Dimensions Diameter 550 mm
Height 135 mm
Weight Less than 29kg
BrainLab: mMLC (Photograph)
mMLC
Linac head
BrainLab: M3-mMLC
No. of leaves 52
Field size at isocentre 100 x 102 mm2
Material Tungsten with special coating
Width at isocentre 3.0 mm – central 14 pairs
4.5 mm – outer 6 pairs
5.5 mm – outermost 6 pairs
Maximum leaf speed 1.5 cm/sec
Movement path Linear/parallel to Y-jaws
End design Curved/rounded
Over travel 50 mm
Position Sensor Linear encoder
Leaf transmission < 2%
Weight 30 Kg
Leaf Transmission/Leakage
Secondary MLC < 2% Tertiary MLC < 5 %
MLC 6 MV
Interleaf
HE-X
Interleaf
6 MV
Avg.
HE-X
Avg.
Elekta 4.1% 4.3%
(20 MV)
1.8% 2%
(20 MV)
Varian --- --- 1.5 -
2.5%
1.5 -
2.5%
(18 MV)
Siemens 1.1% 1.4%
(10 MV)
1.0 % 1.1%
(10 MV)
Requirement : Average transmission
Leaf End Transmission
Transmission through the ends of abutting leaves
Elekta 51% (6 MV)
61% (20 MV)
Varian 28% (18 MV)
Siemens ---------
Leakage Radiation : Varian Millennium
120 and 80 Leaves MLC
Standard (STD) Linac and Flattening Filter Free (FFF)Linac
Linac-‐headcomponents used in a Monte Carlo Simulation.
Building a 6 MV and 10 MV FFF linac model by tuning incident
beam parameters and matching them with measured data in a
fla]ening filter removed standard linac.
Varian True Beam FF and FFF beams
• 3D, IMRT, IGRT, SRS, SBRT,RapidArc
• Photons with FF: 6, 10 and 15 MV
• Photons in FFF mode: 6 and 10 MV
• Electrons: 6, 9, 12, 16 and 20MeV
• Max dose rates & Dose per beam pulse:
• MU/min mGy/pulse
• 6, 10, 15 600 0.28, 0.28,0.56
• 6 FFF 1400 0.65
• 10FFF 2400 1.11
• Electrons 1000
• Cone Beam CT (CBCT)
• kV Imaging
• Electronic Imaging Device (EPID)
Other modern FFF linacs
Cyberknife
Thomotherapy
THANK YOU

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Madical liner accelartaer. Morden radiotherapy

  • 1. Medical Linear Accelerators Dr Rajesh Kumar RPAD BARC
  • 2. Radiation Therapy External Beam Therapy or Teletherapy BrachyTherapy or Endocurie Therapy Nuclear Medicine Co-60 Mega Voltage therapy Electron
  • 3. X-Ray Beam Therapy Grenz-Ray Therapy Contact Therapy Superficial Therapy Medium Voltage Therapy Deep Therapy Soft x-ray below 20KV, low penetrating power, Operate at potential 40-50 KV, very short distance treatment, treatment depth not more than 1-2 mm Operate at potential ranging from 50-150 KV, treatment distance 15-20 cm, useful for tumors confined to about 5mm depth. Operate at potential ranging from 200- 300 KV, treatment distance 50 cm Operate at potential ranging from 150-200 KV
  • 6. Different applicators and filters Orthovoltage (deep) x-ray equipment
  • 7. Grenz super Ortho contact Co-60 Skin sparing effect: low surface dose compared to maximum dose
  • 8. Limitations of Low Energy Machines Can not reach deep-seated tumors with an adequate dosage of radiation. Do not spare skin and normal tissues.
  • 9. •Photon Beam (X-Ray): •4 MV To 22 MV. •Single Beam. •Dual Beams •Electron Beam: •Multi-Beams with energy group between: 4- 22 MeV.
  • 10. What is a Linear Accelerator? •Treatment machine that uses high-frequency electromagnetic waves to accelerate charged particles such as electrons to high energies via a linear tube. Charged particles travel in straight lines as they gain energy from an alternating electromagnetic field. • The resonating cavity frequency of the medical linacs is about 3 billion Hertz (cycles/sec) . • This is the most common device to treat cancer with external beam radiation.
  • 11. How does it work? • The linear accelerator (Linac), uses microwave technology to accelerate electrons in a part of the linac called waveguide, then allows these electrons to collide with a heavy metal target. As a result of these collisions, high energy X-‐Rays (Photons) are produced from the target.
  • 12. How does it work? • These high energy photons will be directed to the patient’s tumor and shaped as they exit the linac to conform to the shape of the tumor. • Radiation can be delivered to the tumor from any angle by rotating the gantry and moving the treatment couch.
  • 13. Early Accelerators The first one was installed at Hammersmith in 1952. In 1956, the first patient was treated at Stanford University in the United States. The Linac had an 8 MV X-‐ray beam with limited gantry motion. These linacs were large and bulky.
  • 14. 2nd Generation Linacs • The second generation, were isocentric units, which can rotate 360 degrees around the gantry axis. • They were built between 1962 and 1982. • They improved in precision and accuracy of dose delivery.
  • 15. 3rd Generation Linacs • Better accelerator waveguides and bending magnet systems and more beam modifying accessories. • Wider range of beam energies, dose rates, field sizes and operating modes. • Higher reliability and computer driven.
  • 17. 1.Gantry 2.Gantry/Drive stand 3.Modulator cabinet 4.Patient Support Assembly (PSA) 5.Control Console Major Components of a LINAC
  • 18. 1) Electron injection system 2) RF power generator 3) Accelerating waveguide 4) Auxiliary system 5) Beam transport system 6) Beam collimation system, and 7) Beam monitoring system Main Beam Forming Components
  • 19. Drive Stand Drive Stand: a stand containing the apparatus that drives the linear accelerator Open on both sides with swinging doors for easy access to gauges, valves, tanks, and buttons Klystron/Magnetron: power source used to generate electromagnetic waves for the accelerator guides Waveguide: hollow tube-like structure that guide the electromagnetic waves from the magnetron to the accelerating guide where electrons are accelerated Circulator: directs the RF energy into the waveguide and prevents any reflected microwaves from returning to the klystron Water-cooling system: allows many components in the gantry and drive stand to operate at a constant temperature
  • 20. The Klystron • Provides the source of microwave power to accelerate the electrons. • This is done by amplifying introduced Radio Frequency (RF) electromagnetic waves.
  • 21. The Magnetron • Electron tube that provides microwave power to accelerate the electrons. • Preferred for lower electron energies, 4 MeV to 6 MeV linacs. • For higher energies the Klystron is a better choice.
  • 22. Electron Gun Electrons produced by thermionic emission
  • 23. Accelerator Guide • This is sometimes called the accelerator structure or accelerator wave guide. • It can be mounted in the gantry horizontally for high energy single or dual energy machines with klystrons. • Can be mounted vertically for low energy machines with magnetrons. • The microwave power produced in the klystron or magnetron is transported to the accelerator structure to accelerate the pulsed electron bunches.
  • 29. Gantry: responsible for directing the photon (x- ray) energy or electron beam at a patients tumor. Electron gun: produce electrons and injects them into the accelerator structure Accelerator structure: a special type of wave guide in which electrons are accelerated. Treatment head: components designed to shape and monitor the treatment beam
  • 30. Pulse Forming Network: • A pulse forming network (PFN) is an electric circuit that accumulates electrical energy over a comparatively long time, then releases the stored energy in the form of a relatively square pulse of comparatively brief duration for various pulsed power applications. • The Thyratron uses these pulses as a high-‐tech switch to deliver these pulses to the electron gun.
  • 31. Treatment Head: Treatment head: components designed to shape and monitor the treatment beam Bending magnet: direct the electrons vertically toward the patient X-ray target, Primary collimator: designed to limit the maximum field size, Beam flattening filter: shaped the x-ray beam in its cross sectional dimension, Ion chamber: monitors the beam for its symmetry in the right-left and inferior-superior direction, Secondary collimators: upper and lower collimator jaws, Field light: outlines the dimensions of the radiation field as it appears on the patient, allows accurate positioning of the radiation field in relationship to skim marks or other reference points
  • 32. Modulator Cabinet: • Modulator cabinet: contains components that distribute and monitor primary electrical power and high-voltage pulses to the magnetron or klystron • This is the noisiest of the linac system components and is located inside the treatment room. • Contains 3 subcomponents: • Fan Control, cooling the power distribution system. • The auxiliary power distribution system, contains the emergency off button that shuts the power to the linac. • Primary power distribution system.
  • 33. Bending Magnet: • Changes the direction of the electron beam, downwards toward the patient. • Bends the pulsed electron beam towards the target for X-‐raysor toward the scattering foil for electron treatments. • Produces different beam paths for different energies. • Needed for energies greater than 6 MeV.
  • 34. Bending Magnet Bending magnet: bends the electron beam through a right angle, so it ends up pointed at the patient 90 degree magnets (chromatic) have the property that any energy spread results in spatial dispersion of the beam. Electrons are bent in proportion with their energy, the lower energy electrons are bent more, the higher energy electrons less Results in a beam that is spread from side to side according to energy Energy sensitive, act as energy differentiators 270 degree magnets (achromatic) designed to eliminate spatial dispersion So not significantly disperse the different electron energies in the beam.
  • 35. 90 Bending of electron beam
  • 38. X-‐RayTarget: • The collision of the electrons with the high density transmission target creates the X-‐Rays (photons), forming a forward peaking shaped X-‐raybeam in the direction of the patient’s tumor. • The X-‐raytarget is located at the focus of the Bending Magnet. • 94% of the electrons energy goes into heat.
  • 39. Linac: components Electron Gun Target Cut-away view of a standing wave accelerating waveguide for a 6 MV linac. The accelerating cavities are on the central axis, the coupling cavities are off- side.
  • 40.
  • 41. The Water Cooling System Located in the Drive Stand and Gantry • Provides thermal stability to the system. • Allows many components in the Drive Stand and Gantry to operate at a constanttemperature.
  • 42. Beam Flattening Filter: • It is a conical shaped metal absorber, that absorbs more forward peaking photons than the ones in the periphery. • Shapes the X-‐rays in their cross sectionalshape. • It is required to create a flattened beam of sufficient area, uniformity and symmetry. • It is usually made of Tungsten, Steel, Lead, Uranium and Aluminum. • In dual energy photon linacs, two flattening filters are required for the low and the higher photon energies.
  • 43. Scattering Foils: • The electron beams have pencil-‐like shapes. • These narrow pencil beams need to be broadened to clinical useful beams and need to be made uniform. • There is a different scattering foil for each electron beam energy produced. • Made out of Aluminum or Cooper. • A thin foil (or multiple ones)are used, they are measured in mils, i.e. 8 mils of Al is about 0.2 millimeters.
  • 44. Carousel in Standard LINAC Carousel
  • 45. Monitor Ionization Chambers: • They monitor integrated Dose, Dose Rate and Field Symmetry. • The radiation that leaves the X-‐RayTarget or the electron Scattering Foils will pass through dual monitor ionization chambers, and they produce an ionization current. • This ionization current is proportional to the X-‐ray of electron beamintensity.
  • 46. Linac: Alignment of electron beam to target
  • 48. Collimators: • The radiation beams are collimated by adjusting the upper and lower collimator jaws. • The jaws are made of High Z number, like Tungsten or Lead. • The jaws can define a rectangular shaped beam up to 40 cm by 40 cm for X-‐raybeams.
  • 49. Treatment Couch: • The treatment couch or table is where the patient lays still to receive the radiation treatment. • It moves Up/Down, Right/Left and In/ Out. • Robotic couches are being used in some linacs nowadays for 3 more degrees of freedom.
  • 51.
  • 52.
  • 53.
  • 54. ‫ع‬ ‫ﻉ‬ ‫ر‬ ‫ﺭ‬ ‫س‬ ‫ﺱ‬ ‫م‬ ‫ﻡ‬ ‫ل‬ ‫ﻝ‬ ‫ا‬ ‫ﺍ‬‫ة‬ ‫ﺓ‬ ‫ي‬ ‫ﻱ‬ ‫س‬ ‫ﺱ‬ ‫ي‬ ‫ﻱ‬ ‫ئ‬ ‫ﺉ‬ ‫ر‬ ‫ﺭ‬ ‫ل‬ ‫ﻝ‬ ‫ا‬ ‫ﺍ‬‫ا‬‫ء‬‫ﺍ‬‫ز‬‫أﺝجﺯ‬‫ﺃ‬‫ل‬‫اﻝ‬‫ﺍ‬ ‫ي‬ ‫ﻱ‬ ‫ط‬ ‫ﻁ‬ ‫خ‬ ‫ﺥ‬ ‫ل‬ ‫ﻝ‬ ‫ا‬ ‫ﺍ‬ Electron gun Accelerator Wave guide Target Bending magnet Carrousel with fla]ening filters and foils Transmission Ion Chambers MLC’s ‫ة‬ ‫ﺓ‬ ‫ي‬ ‫ﻱ‬ ‫ع‬ ‫ﻉ‬ ‫ا‬‫ﺍ‬ ‫ع‬ ‫ﻉ‬ ‫ش‬ ‫ﺵ‬ ‫إ‬‫ﺇ‬ ‫ل‬ ‫ﻝ‬ ‫ا‬‫ﺍ‬‫ة‬‫ﺓ‬ ‫م‬‫ﻡ‬ ‫ﺯز‬ ‫ﺡح‬ ‫ﻝل‬ ‫ا‬‫ﺍ‬
  • 55. Electron beam accelerated in wave guide Forward peaked X-‐ray beam X-‐RayTarget Flattening Filter Electron scattering foil Secondary Collimator jaws X-‐rayBeam central axis Accessory Holder Slot
  • 56. Electron Beam path Accelerated electronbeam X-‐ray targetremoved Scattering Foil Transmission monitor ion chambers Accessory Mount Electron Beam Central Axis Electron cone or applicator
  • 57. ‫ع‬ ‫ﻉ‬ ‫ر‬ ‫ﺭ‬ ‫س‬ ‫ﺱ‬ ‫م‬ ‫ﻡ‬ ‫ل‬ ‫ﻝ‬ ‫ا‬ ‫ﺍ‬‫ة‬ ‫ﺓ‬ ‫ي‬ ‫ﻱ‬ ‫س‬ ‫ﺱ‬ ‫ي‬ ‫ﻱ‬ ‫ئ‬ ‫ﺉ‬ ‫ر‬ ‫ﺭ‬ ‫ل‬ ‫ﻝ‬ ‫ا‬ ‫ﺍ‬‫ا‬‫ء‬‫ﺍ‬‫ز‬‫أﺝجﺯ‬‫ﺃ‬‫ل‬‫اﻝ‬‫ﺍ‬ ‫ي‬ ‫ﻱ‬ ‫ط‬ ‫ﻁ‬ ‫خ‬ ‫ﺥ‬ ‫ل‬ ‫ﻝ‬ ‫ا‬ ‫ﺍ‬ Electron gun Accelerator Wave guide Target Bending magnet Carrousel with fla]ening filters and foils Transmission Ion Chambers MLC’s ‫ة‬ ‫ﺓ‬ ‫ي‬ ‫ﻱ‬ ‫ع‬ ‫ﻉ‬ ‫ا‬‫ﺍ‬ ‫ع‬ ‫ﻉ‬ ‫ش‬ ‫ﺵ‬ ‫إ‬‫ﺇ‬ ‫ل‬ ‫ﻝ‬ ‫ا‬‫ﺍ‬‫ة‬‫ﺓ‬ ‫م‬‫ﻡ‬ ‫ﺯز‬ ‫ﺡح‬ ‫ﻝل‬ ‫ا‬‫ﺍ‬
  • 58. Multi Leaf Collimators (MLC’s) • They are heavy metal field-‐shapingdevices with independent moving mechanisms used to create a custom like block to spare normal tissue and direct the radiation dose to the tumor. • The MLC’s became a key element in the treatment delivery of X-‐raybeams with IMRT (Intensity Modulated Radiation Therapy).
  • 59.
  • 63. Availability of MLC MLCs are available from all the major medical LINAC manufacturers : Elekta Siemens Varian Independent manufacturers: BrainLab Radionics Direx NOMOS Novalis
  • 64. MLC Conventional Secondary Tertiary Singly Focused Doubly Focused OR Mini Micro Single Plane Double Plane OR Miniature
  • 66. RPT_72 AAPM TG50: terminology Leaf width: small leaf dimension perpendicular to the motion direction (and to propagation direction) Leaf length: leaf dimension parallel to the motion direction (and to propagation direction) Leaf end: the surface of the leaf inserted into the field along this dimension Leaf side: the surfaces in contact with adjacent leaves Height of the leaf: the dimension of the leaf along the direction of propagation of the primary x-ray beam (from the top of the leaf near the x- ray source to the bottom of the leaf nearest the isocenter (attenuation properties)
  • 67. RPT_72 AAPM TG50: transmission Leaf transmission: the reduction of dose through the full height of the leaf Interleaf transmission: the reduction of dose measured along a line passing between leaf sides End transmission: the reduction of dose measured along a ray passing between the ends of opposed leaves in their most closed position MLC transmission: the average of leaf and interleaf transmissions (should be less than 2%) TPS parameter
  • 68. MLC - leaf end shape
  • 69. MLC – leafside: The Tongue and Groove a tongue-and- on is divided f the two • To reduce groove des • If a large f into two s treatment f the interleaf leakage some MLCs are using ign ield perpendicular to the leaf motion directi ubfields, an underdosage at the matchline o ields is observed (IMRT, VMAT)
  • 70. Huq et al., PMB 47, 2002
  • 71. MLC – motion constraints Leaf over-travel: the maximum distance over the beam CAX to which an MLC leaf can travel Leaf span: the maximum distance from the tip of the most retracted leaf to the tip of the most extended leaf
  • 72. MLC - The Interdigitation • It is the ability of leaves on one side of a field to interdigitate with neighboring leaves on the opposing leaf bank • The ends of odd-numbered leaves from the right-hand bank are driven past the ends of even- numbered leaves from the left-hand bank • The Varian collimator was the first commercial system that could perform it
  • 73. MLC configuration in the Treatment Head
  • 74. MLC – Varian configuration Terziary, 3rd level (or Add-on) Collimator
  • 75. HEAD ASSEMBLY of Elekta LINAC The upper jaw (Y) is replaced by the MLC leaves and a back-up diaphragm (Y-back) placed beneath the leaves follows the leaves to provide additional attenuation.
  • 76. ELEKTA MLC: Y-Jaw replacement No. of leaves 80 Material Tungsten Thickness (height) 7.5 cm Arrangement Tongue and Groove Width at isocentre 1.0 cm Movement path Linear End design Curved/rounded Focusing Single Interdigitization of opposite leaves Possible Position Sensor Optical/CCD camera Back-up jaw thickness 3.0 cm Field size at isocentre 40 x 40 cm2
  • 77. MLC – Elekta configuration Upper Jaw replacement MLC
  • 79. MLC – Elekta design (1) • MLC closest to source • Rounded leaf-end Single focused • The MLC leaves move in the y-direction ………………………………………………………………………. • Backup collimator moving with MLCs • A “back-up” collimator, located beneath the leaves and above the lower jaws, augments the attenuation provided by the individual leaves • The back-up is essentially a thin upper jaw that can be set to follow the leaves if they are being ganged together to form a straight edge or else set to the position of the outermost leaf if the leaves are forming a shape
  • 80. MLC – Elekta design (2) • The primary advantage of the upper jaw replacement design is that the range of motion of the leaves required to traverse the collimated field width is smaller, allowing for a shorter leaf length and therefore a more compact treatment head diameter ……………………………………………………………………….. • The disadvantage of having the MLC leaves so far from the accelerator isocenter is that the leaf width must be somewhat smaller and the tolerances on the dimensions of the leaves as well as the leaf travel must be tighter than for other configurations.
  • 82. MLci2TM MLCi2™ Width leaf (@iso) 10 mm Number of leaves 80 (40 pairs) Max field size (@iso) 40 cm x 40 cm Over-travel 12.5 cm Focalized single Thickness 8.2 cm Interdigitation yes Penumbra < 7 mm (5 cm x 5 cm to 15 cm x 15 cm) < 8 mm (> 15 cm x 15 cm) RT delivery 3DCRT-IMRT-VMAT
  • 83. MLC Elekta Beam Modulator™ Beam Modulator™ Width leaf (@iso) 4 mm Number of leaves 80 (40 pairs) Max field size (@iso) 16 cm x 21 cm Over-travel full Focalized single Thickness 7.5 cm Interdigitation yes Back-up collimator no Penumbra < 4 mm (up to 5 cm x 5 cm) < 5 mm (up to 10 cm x 10 cm) < 6 mm (> 10 cm x 10 cm) RT delivery 3DCRT-IMRT-VMAT
  • 84. µMLC Elekta Apex™ Apex™ (add-on) Width leaf (@iso) 2.5 mm Number of leaves 112 (56 pairs) Max field size (@iso) 12 cm x 14 cm Over-travel ¾ field size Focalized double Thickness 8 cm Interdigitation yes Junction Tongue and groove Penumbra < 3.5 mm RT delivery 3DCRT-IMRT-S&S no VMAT
  • 85. MLC – the new Elekta configuration: complete upper replacement (opposite of Siemens design)
  • 86. The Elekta MLC AgilityTM • Number of leaves: 160 • Interdigitation: yes • Material: W-alloy leaves • Width (@ isocentre): 5 mm • The leaves are mounted on dynamic leaf guides that can move up to 15 cm; relative to the guide the leaves can extend up to 20 cm • Leaf sides: flat • The gaps between the leaves: tilted to reduce overall transmission • The single pair of diaphragms are a novel, sculpted design to reduce their thickness where leaves will always provide additional shielding They move perpendicular to the MLC and can over-travel the central axis by up to 12 cm; both the leaf and diaphragm ends arerounded.
  • 89. Leaves shift towards the region with minor leakage AgilityTM
  • 91. MLC – Varian configuration • It is positioned just below the level of the standard upper and lower jaws • This is “ok” for maintenance actions • Disadvantage: the added bulk and the minor clearance to the mechanical isocenter • Moving the MLC farther from the x-ray target requires an increase in the size of the leaves and a longer travel distance to move from one side of the field to the other • The result is that such a tertiary system decreases the collision free zone • In IMRT, to cover large fields, it can become necessary to split the field in 2 or 3 sub-fields (different carriage positions)
  • 92. Clearance head MLC Largest Block tray Wedge Elekta 45 cm 35.3 cm 35.3 cm Siemens 43 cm 43 cm 43 cm Varian 42 cm 35 cm 35 cm
  • 93. MLC – Varian design • Rounded leaf-end • Single focused • No backup jaw moving with MLCs
  • 94. MLC – Varian Millenium120TM o The leaves travel on a carriage to extend their movement across the field o Leaf interdigitation: yes o The distance between the most extended leaf and the most retracted leaf on the same side (carriage) can be up to 15 cm o Max field length X-direction: 40 cm o Max leaf retract position (from CAX): 20.1 cm o Max leaf extend position (over CAX): -20cm o Leaf width in the central 20 cm of field: 5 mm o Leaf width in outer 20 cm of field: 10 mm o Maximum speed: 2.5 cm/s o Leaf height: 60 mm o Leaf end radius: 80 mm o Leaf tongue and groove offsets: 0.4mm o W-alloy
  • 95. Leaf motion constraints VARIAN Millenium120TM Extending the leaves out to the field center is not possible when large fields are used. This can be illustrated by a medium field size of 20-cm width that is symmetric relative to the field center. Here, the entire carriage can be moved so that the leaves can extend 5 cm (the 15 cm limit minus the 10 cm half field width) over the field center
  • 96. MLC – Varian 2.5 mm HD120TM • The width of the central leaves is 2.5mm • Each side of the Varian collimator is configured with 60 leaves distributed in an 8 cm wide central region with 32x2.5 mm leaves, flanked by two 7 cm wide outer regions with 14x5.0 mm leaves, for a total width of 22cm • Maximum static field size: 40 x 22 cm2 • MLC mounted on Varian True BeamTM True BeamSTx TM
  • 98. Siemens MLC All the leaves are independently controlled. The leaves may be manually positioned with an MLC hand control. Leaf settings can be uploaded to an information management Record and Verify (R&V) system.
  • 99. End-on view of the Siemens MLC truncated pie shape of the leaves as well as the leaf side shape to reduce interleaf transmission
  • 100. SIEMENS MLC:X-Jaw Replacement No. of leaves 58 Field size at isocentre 40 x 40 cm2 Material Tungsten Thickness (height) 7.6 cm Arrangement Tongue and Groove Width at isocentre 1.0 cm – inner 27 pairs 6.5 cm – outer 2 pairs Movement path Circular arc End design Straight Focusing Double Interdigitization Not Possible Position Sensor Linear encoders
  • 101. •Double focused (Conic geometry) •Lower leakage •Minimized penumbra independent of leave position •Flat edges (no rounded edges) •No gap between closed leaves •No carriage (no IMRT segmentation in 2 fields
  • 103. MLC – Siemens design • MLC replaces completely secondary collimator • The leaf ends are straight and are focused on the x-raysource • The leaf ends as well as the leaf sides match the beam divergence, making the configuration double-focused • Y-jaw backups each MLC segment
  • 104. Siemens MLC leaf ends Siemens linacs use MLCs that move in an arc such that the flat faces of the leaf ends are always in the same plane as the radiation focus
  • 107. Patient-support • Patient support and positioning devices are designed to implement a given treatment technique • Important criteria include patient comfort, stability, and reproducibility of set-up and treatment geometry that allows accurate calculation and delivery of dose
  • 108. Treatment couch - movements 4 degrees of movements: vertical, transversal, longitudinal, yaw 6 degrees movements: vertical, transversal, longitudinal, yaw, pitch, roll (with remote robotic control capability)
  • 109. Treatment couch - rotations • PITCH: rotation around the X-axis • ROLL: rotation around the Y-axis • YAW: rotation around the Z-axis
  • 110. Treatment couch - tabletop • Current linac couch has special top consisting in a carbon fiber table • The carbon fiber plates sandwiched with a plastic foam core • The carbon fiber construction ensures that no metal parts are used in the entire treatment area Seppala, Kulmala, J App Cl Med Phys 12(4), Fall 2011
  • 111. Elekta HexaPOD™ evo (6 DOF) baseboard Connexion Short Indexing Bar IGRT module
  • 112. Varian Exact™ IGRT (4 DOF) Varian PerfectPitchTM (6 DOF) Maximum pitch and roll is ± 3.0 degrees
  • 113. HEAD ASSEMBLY OF VARIAN LINAC
  • 114. VARIAN MLC: Tertiary Material Tungsten Thickness (height) 5.0 cm Arrangement Tongue and Groove Movement path Linear End design Curved/rounded Focusing Single Interdigitization Possible Position Sensor Linear encoders Standard Millennium HDMLC
  • 115. Design of Varian Millennium MLC Comparatively less Out-of-field leakage
  • 116. Varian MLCs ----------------------------------------------------------------------------------- Model No. Leaves Field Size Leaf widths @ Isocenter ----------------------------------------------------------------------------------------------------- Millennium MLC-52 52 26 x 40 cm2 10 mm Millennium MLC-80 80 40 x 40 cm2 10 mm Millennium MLC-120 120 40 x 40 cm2 Centre: 5 mm, 40 pairs Periphery: 10 mm, 20 pairs HDMLC 120 40 x 22 cm2 Centre: 2.5 mm, 32 pairs Periphery: 5 mm, 28 pairs BrainLAB-m3 52 10 x 10 cm2 3.0 mm, 4.5 mm, and 5.5 mm -----------------------------------------------------------------------------------------------------
  • 118. Comparison of leaf assembly (End-on view) Elekta Varian Siemens
  • 119. A comparison of leaf over travel configurations
  • 120.
  • 121. Direx Acculeaf: Four Bank mMLC BEV of AccuLeaf aperture showing both levels AccuSoft BEV with Digitally Reconstructed Radiographs (DRR) using AccuLeaf
  • 122. AccuLeaf - Specifications Number of leaves 96 leaves (4 banks in perp. orientation) Clearance ~ 300 mm LINAC dependent Leaf material Wolfram (high grade) Leaf height set in two levels, 38 mm each (total 76 mm) Leaf width - 14 inner leaves ~3.1 mm at isocentre at isocentre ~2.6 mm effective - 10 outer leaves ~5.3 mm at isocentre Field size at isocentre ~ 100 x 110 mm Max. leaf travel at isocentre ~93 mm Max. leaf over travel at isocentre ~ 33 mm Dimensions Diameter 550 mm Height 135 mm Weight Less than 29kg
  • 124. BrainLab: M3-mMLC No. of leaves 52 Field size at isocentre 100 x 102 mm2 Material Tungsten with special coating Width at isocentre 3.0 mm – central 14 pairs 4.5 mm – outer 6 pairs 5.5 mm – outermost 6 pairs Maximum leaf speed 1.5 cm/sec Movement path Linear/parallel to Y-jaws End design Curved/rounded Over travel 50 mm Position Sensor Linear encoder Leaf transmission < 2% Weight 30 Kg
  • 125. Leaf Transmission/Leakage Secondary MLC < 2% Tertiary MLC < 5 % MLC 6 MV Interleaf HE-X Interleaf 6 MV Avg. HE-X Avg. Elekta 4.1% 4.3% (20 MV) 1.8% 2% (20 MV) Varian --- --- 1.5 - 2.5% 1.5 - 2.5% (18 MV) Siemens 1.1% 1.4% (10 MV) 1.0 % 1.1% (10 MV) Requirement : Average transmission
  • 126. Leaf End Transmission Transmission through the ends of abutting leaves Elekta 51% (6 MV) 61% (20 MV) Varian 28% (18 MV) Siemens ---------
  • 127. Leakage Radiation : Varian Millennium 120 and 80 Leaves MLC
  • 128. Standard (STD) Linac and Flattening Filter Free (FFF)Linac Linac-‐headcomponents used in a Monte Carlo Simulation. Building a 6 MV and 10 MV FFF linac model by tuning incident beam parameters and matching them with measured data in a fla]ening filter removed standard linac.
  • 129. Varian True Beam FF and FFF beams • 3D, IMRT, IGRT, SRS, SBRT,RapidArc • Photons with FF: 6, 10 and 15 MV • Photons in FFF mode: 6 and 10 MV • Electrons: 6, 9, 12, 16 and 20MeV • Max dose rates & Dose per beam pulse: • MU/min mGy/pulse • 6, 10, 15 600 0.28, 0.28,0.56 • 6 FFF 1400 0.65 • 10FFF 2400 1.11 • Electrons 1000 • Cone Beam CT (CBCT) • kV Imaging • Electronic Imaging Device (EPID)
  • 130. Other modern FFF linacs Cyberknife Thomotherapy