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LYMPHADENOPATHY
(LYMPHADENITIS)
INTRODUCTION
• Lymph nodes can be enlarged - inflammation
(lymphadenitis) or infiltration (neoplastic
cells)
• Enlargement of peripheral nodes causes
visible and palpable swellings
• some cases obstruction lymphatic drainage
and subsequent local edema
• Enlargement of internal nodes may cause
obstruction of esophagus, pharynx, trachea or
bronchi
• Infection or neoplastic invasion
Aetiology
• Caseous lymphadenitis of sheep
• Cattle due to infection with corynebacterium
pseudotuberculosis
• Anthrax
Cervical lymphadenopathy
Inflammation and swelling in the pharyngeal
region and neck
• Tularemia- Francisella tularensis, in tick-
infested sheep
• Melioidosis associated infection with
Pseudomonas (Malleomyces) pseudomallei
• Tick pyemia associated with Staphylococcus
aureus in sheep infested with tick Ixodes
ricinus
• Retropharyngeal lymph node enlargement
colored bright green - Cattle - algae
Prototheca Spp
• Tuberculosis
• Lambs - P multocida, and actinobacillosis
• Morel's disease of sheep - micrococcus
• Bovine farcy and atypical skin tuberculosis
• Later involving lymphatics but not associated
with
• Lymph node enlargement
CLINICAL SIGNS
•Infection and enlargement of lymph
Nodes
• Acute lymphadenitis
Pain and heat on palpation but nodes
are for most part painless
•Obstructions- secondary signs
Respiratory difficulty with enlargement
of retropharyngeal lymph nodes
Esophageal obstruction by enlarged
mediastinal lymph nodes
Diagnosis
• History and clinical signs
• CBC
• Needle biopsy for cytology and culture (cause
and differentiation)
Lymphadenitis and neoplastic enlargement
• Ultrasound absence of lymphoid tissue
occurs
Treatment
• Cause should be treated
LYMPHANGITIS
Clinical signs
• ulcerative lymphangitis, abscesses and
pyogranulomatous lesions
• Hindlegs & interdigital space
• nodular lesions on flanks or stifle joints, on
both the dorsal and palmar aspects hindleg
• Appearance of small nodules under skin of
shoulders, ribs, and flanks
• Subsequent involvement of prescapular and
precrural glands.
• Disease followed a wound
• Actinomycosis , Corynebacterium
• Abscesses were multiple, more pronounced,
doughy on palpation or with palpable fluid
inside, and painful
• Fibrous tissue capsule and firmer consistency
• Once ulceration developed- secretion of
yellowish pus
Differential diagnoses
• Pyoderma, abscesses or lymphangitis due to
other skin pathogens
(eg, staphylococcus aureus, streptococcus spp or dermatophilus spp)
• Bovine dermatophilosis (dermatophilus
congolensis)
• Dermatophytosis, sporotrichosis,
cryptococcosis, blastomycosis and
onchocerciasis.
• LSD
Diagnosis
• Culture and sensitivity
• PCR
Treatment
• Surgical drainage of abscesses in individual
severely affected animals
• chemical cauterisation with 10 per cent
iodine solution
• 20,000 IU/kg of penicillin G (intramuscularly)
- Antibiotic therapy
• Anti inflammatory
THANK YOU…….

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lymphadenopathy.pptx

  • 2. INTRODUCTION • Lymph nodes can be enlarged - inflammation (lymphadenitis) or infiltration (neoplastic cells) • Enlargement of peripheral nodes causes visible and palpable swellings • some cases obstruction lymphatic drainage and subsequent local edema
  • 3. • Enlargement of internal nodes may cause obstruction of esophagus, pharynx, trachea or bronchi • Infection or neoplastic invasion
  • 4. Aetiology • Caseous lymphadenitis of sheep • Cattle due to infection with corynebacterium pseudotuberculosis • Anthrax Cervical lymphadenopathy Inflammation and swelling in the pharyngeal region and neck
  • 5. • Tularemia- Francisella tularensis, in tick- infested sheep • Melioidosis associated infection with Pseudomonas (Malleomyces) pseudomallei • Tick pyemia associated with Staphylococcus aureus in sheep infested with tick Ixodes ricinus • Retropharyngeal lymph node enlargement colored bright green - Cattle - algae Prototheca Spp • Tuberculosis
  • 6. • Lambs - P multocida, and actinobacillosis • Morel's disease of sheep - micrococcus • Bovine farcy and atypical skin tuberculosis • Later involving lymphatics but not associated with • Lymph node enlargement
  • 7. CLINICAL SIGNS •Infection and enlargement of lymph Nodes • Acute lymphadenitis Pain and heat on palpation but nodes are for most part painless •Obstructions- secondary signs Respiratory difficulty with enlargement of retropharyngeal lymph nodes Esophageal obstruction by enlarged mediastinal lymph nodes
  • 8. Diagnosis • History and clinical signs • CBC • Needle biopsy for cytology and culture (cause and differentiation) Lymphadenitis and neoplastic enlargement • Ultrasound absence of lymphoid tissue occurs
  • 11. Clinical signs • ulcerative lymphangitis, abscesses and pyogranulomatous lesions • Hindlegs & interdigital space • nodular lesions on flanks or stifle joints, on both the dorsal and palmar aspects hindleg
  • 12. • Appearance of small nodules under skin of shoulders, ribs, and flanks • Subsequent involvement of prescapular and precrural glands. • Disease followed a wound • Actinomycosis , Corynebacterium
  • 13. • Abscesses were multiple, more pronounced, doughy on palpation or with palpable fluid inside, and painful • Fibrous tissue capsule and firmer consistency • Once ulceration developed- secretion of yellowish pus
  • 14. Differential diagnoses • Pyoderma, abscesses or lymphangitis due to other skin pathogens (eg, staphylococcus aureus, streptococcus spp or dermatophilus spp) • Bovine dermatophilosis (dermatophilus congolensis) • Dermatophytosis, sporotrichosis, cryptococcosis, blastomycosis and onchocerciasis. • LSD
  • 15. Diagnosis • Culture and sensitivity • PCR
  • 16. Treatment • Surgical drainage of abscesses in individual severely affected animals • chemical cauterisation with 10 per cent iodine solution • 20,000 IU/kg of penicillin G (intramuscularly) - Antibiotic therapy • Anti inflammatory

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