The document discusses different types of lung cancer including squamous cell carcinoma (SCC), adenocarcinoma (ADCL), large cell carcinoma (LCLC), and small cell lung carcinoma (SCLC). It provides details on characteristics such as location in the lung, histological features, associations with paraneoplastic syndromes, and common symptoms. SCC is centrally located and produces cavitary lesions. ADCL occurs in non-smokers, women, and peripherally located. SCLC commonly affects males and is centrally located producing numerous paraneoplastic effects.

1. SMOLENSK STATE MEDICAL
UNIVERSITY
THE DEPARTMENT OF HOSPITAL SURGERY
Topic - LUNG CANCER
- Вахланг Зеана Мари
-501

8. SCC:
Centrally located
Produces Cavitary lesions
Causes obstruction
Association with- Para-
Neoplastic syndrome:
Hypercalemia due to PTH
H/E- Desmoses and
Pearls seen

10. ADCL:
Non-smokers
Women
Peripherally located
Paraneoplastic Syn-
Migratory Thrombophlebitis
Tumor cells grow along the
intertubular lining
Filigree pattern
H/E Glands lined by
epithelium

12. LCLC:
Sheets of highly
pleomorphic
cells
Centrally
Diagnosis of
exclusion

13. SCLC
Males> Females
Centrally located
Produces Maximum Para
Neoplastic Syndrome
H/E:
Small cells, scanty
cytoplasm
Nuclear molding
Necrosis

15. Azzopardi effect
Granular Chromatin :
Salt and Pepper
Chromatin
Fragile cells break
and releases DNA
which deposits in the
blood vessel wall
producing basophillic
staining

17. MC - Cough
Dyspnoea and hemoptisis
Horner’s Syn-Caused by
lung carcinoma at the Apex.
(Pancoast Tumor)
Ptosis
Miosis
Enophthalmus
Anhidrosis
Loss of cilio spinal reflex.