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Luis Miguel Flórez Castaño.
III Semestre de Medicina.
Universidad pontificia Bolivariana.
Introduction
Introduction
Pseudomonas aeruginosa.
-What is the Pseudomonas aeruginosa?
-What color Gram has the Pseudomonas aeruginosa?
-What is the Conformation of the Pseudomonas aeruginosa?
T3SS
T3SS
T3SS
-Virulence Factor.
-Cytotoxicity.
-ExsA.
-RpII.
Objective
Objective
Objective
In the present report, we identified rplI as a repressor for expression of
the T3SS in P. aeruginosa through a genetic screen for isolates with altered
T3SS expression in the mPAO1 strain.
Metodology
Metodology
Metodology
-PCR.
-SDS PAGE.
-PCRq.
-MST.
These were some of the tests used
in the experiment.
PCR PCRq
SDS PAGE
MST
RESULTS
RESULTS
RESULTS
RESULTS
RESULTS
RESULTS
Zhang YF, Han K,
Chandler CE, Tjaden B,
Ernst RK, Lory S
In addition, Sr0161 directly targets the leader region
through base pairing and inhibits ExsA synthesis at the
posttranscriptional level.



 
 


 
 


 
 

Discussion
Discussion
Discussion
The bacterial rplI gene encodes ribosomal large subunit
(50S) protein L9 which is a primary 23S rRNA binding
protein with N- and C-terminal globular domains, both
containing a predicted RNA binding site connected by
an exposed α-helix
Saito K, Mattheakis
LC, Nomura M
demonstrated to control the translation
of exsA through its 74 nt 50 UTR .
Li S, Weng Y, Li X, Yue
Z, Chai Z, Zhang X
Conclusions
Conclusions
Conclusions
The molecular tests developed in this article help in
the medical field to recognize different therapeutic
points before a bacterium with high virulence that
causes various diseases in us humans.
In this article you can borrow so that new approaches of
antibiotics against bacterium can be found since the resistance
exerted by bacterium to these is greater day by day and this
opens new possibilities to focus the treatment to patients
suffering from diseases related to the Pseudomona.
Luis miguel flórez castaño

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