Leyna is diagnosed with COPD (chronic obstructive pulmonary disease), a condition in which the alveoli are destroyed leaving less surface area for oxygen to get into the blood, and for carbon dioxide to leave the blood. This results in hypoxia and hypercapnia. What effect, if any, would this have on Leyna's erythropoietin (EPO) secretion and hematocrit? Decreased erythropoietin (EPO) secretion and hematocrit. Decreased erythropoietin (EPO) secretion and increased hematocrit. Increased erythropoietin (EPO) secretion and hematocrit. Increased erythropoietin (EPO) secretion and decreased hematocrit. No effect on either..