This document provides information about leprosy (Hansen's disease), including: - It is a chronic, curable infectious disease caused by the Mycobacterium leprae bacteria. It mainly affects the peripheral nerves and skin. - Leprosy has been recognized in many parts of the world throughout history. It is one of the oldest recorded diseases. - Leprosy is clinically classified as either multibacillary or paucibacillary. It is also classified based on the immune status and symptoms of the patient. - Treatment involves multidrug therapy with antibiotics and other medications, as well as surgery in some cases.

1. .
Name – Kavyashree Dhananjay Ghongade
LEPROSY DISEASE

2. .
- Leprosy is also known as “Hansen’s disease.
- It is chronic curable infectious disease.
- Mycobacterium leprae.
- Mainly involve the peripheral nerves and skin.
Introduction

3. History
- Recognized in China, India and Egypt.
- It is oldest recorded disease.
- Indians wrote about sounded like leprosy in 600 B.C.
- The earliest documented account of leprosy is around 1550 B.C on
Egyptian papyrus.
- In 1873 Dr.Gehard Henrik Ar mauer Hausend Was found this
disease.

4. Classification of leprosy
According to Immune status of patient –
Tuberculoid
(TT)
Borderline(BL)
Borderline
(BB)
Borderline
Lepromatous (BL) Lepromatous (LL)

5. Clinical classification of
leprosy
1. •Multibacillary
2. •Paucibacillary

6. Pathogenesis
- Leprosy target cell Schwann cell.
- Causes Anesthesia muscle paralysis.
- Repeated injuries to Anesthetic areas leads to gradual distribution.
- Infiltration of skin, subcutaneous lesions leads to formation of visible
lesions.
- First lesions is nonspecific indeterminate skin lesions.

7. Diagnosis
- Skin biopsy
- Skin smear test.
- Lepromin skin test.
- Clinical findings.
- Lymphocyte Migration Inhibition Test
(LMIT).
- CBC Test.
- Creatinine test.

8. Causes
- Mycobacterium leprae.
- Mycobacterium tuberculosis.
- Mycobacterium lepromatosis.

9. Symptoms
Tuberculoid
leprosy
Lepromatous leprosy
Severe pain Thickened skin on face
Muscle weakness Bloody nose
Loss of finger toes Laryngitis
Blindness Swelling of lymph node in groin and armpits

10. Treatment
- Multidrug therapy
- Several antibiotic – Ofloxacin ,Minocycline
- Anti inflammatory medication
- Steroid medication
- Surgery

11. Thank
You…