This presentation contain information about molecular biology and laboratory technics, specially alternative splicing.
all of them to try to explain cancer etiology, give on the molecular bases.
This presentation contain information about molecular biology and laboratory technics, specially alternative splicing.
all of them to try to explain cancer etiology, give on the molecular bases.
Analysis Analysis Analysis Analysisof the entire entire entire protein protein proteinproteincomplementcomplement complement complement of acell, cell, tissue, tissue, tissue, or organism organism organism under under aspecific, specific, specific, defined defined set of conditions conditions conditions .
• Relies Relies Relies on 3basic technological technological technological technological technological cornerstones cornerstones cornerstones cornerstones
• MethodMethod MethodMethod to fractionatefractionate fractionatefractionate fractionatefractionate complexcomplex complex protein/protein/ protein/ protein/ peptide peptide peptidemixturesmixtures mixtures
• MS to acquire acquire the data data necessary necessary to identify identify identifyidentifyindividual individual individual individualproteins proteins
• Bioinformatics Bioinformatics Bioinformatics Bioinformatics Bioinformatics Bioinformatics Bioinformaticsto analyze analyze and assemble assemble the MS data
An understanding towards genetics and epigenetics is essential to cope up with the paradigm shift which is underway. Personalized medicine and gene therapy will confluence the days to come.
This review highlights traditional approaches as well as current advancements in the analysis of the gene expression data from cancer perspective.
Due to improvements in biometric instrumentation and automation, it has become easier to collect a lot of experimental data in molecular biology.
Analysis of such data is extremely important as it leads to knowledge discovery that can be validated by experiments. Previously, the diagnosis of complex genetic diseases has conventionally been done based on the non-molecular characteristics like kind of tumor tissue, pathological characteristics, and clinical phase.
The microarray data can be well accounted for high dimensional space and noise. Same were the reasons for ineffective and imprecise results. Several machine learning and data mining techniques are presently applied for identifying cancer using gene expression data.
While differences in efficiency do exist, none of the well-established approaches is uniformly superior to others. The quality of algorithm is important, but is not in itself a guarantee of the quality of a specific data analysis.
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http://inplanttrainingchennai.com/
HUMAN PAPILLOMAVIRUS IS A NECESSARY CAUSE OF INVASIVE CERVICAL CANCER WORLD-WIDEAlberto Cuadrado
Infection with oncogenic human papillomavirus (HPV) is the major risk factor in the aetiology of cervical cancer. In a
previous study of invasive cervical cancers collected from 22 countries (the International Biological Study on Cervical
Cancer, IBSCC), however, the PCR assay used failed to detect HPV DNA in 7% of samples. The current study
re-examined these so-called HPV-negative samples, as well as a proportion of the originally positive samples, using a
more stringent procedure to ensure the presence of carcinoma cells within the material used for PCR. In addition,
three different PCR assays targeting different open reading frames were used, to avoid misclassifying as negative
samples in which integration of HPV DNA had led to disruption of the PCR primer sequences or loss of the HPV L1
open reading frame, the target of the PCR assay used in the original study. Furthermore, sera from the patients
originally classified as HPV-negative were assayed for antibodies against viral-like particles (VLPs) and E6 and E7
proteins of HPV 16, which accounts for about 50% of HPV-positive cervical cancers world-wide.
Of those serum samples tested, antibodies to at least one HPV 16 protein were detected in a similar proportion of
those originally classified as HPV-negative or -positive: 56% and 67%, respectively. There was no significant difference
between the two groups in the proportion of antibodies reactive to VLPs, E6 or E7. After excluding histologically
inadequate samples (87%), only 6% of those initially classified as HPV-negative remained negative to all the PCR
assays used for retesting. Thus the true incidence of HPV-positive samples in the IBSCC is 99.7%.
Most of the HPV-negative samples in the earlier study proved to have been misclassified since a more stringent
testing procedure revealed them to be HPV-positive. The similarity of the serum antibody profiles from patients with
cancers originally classified as HPV-positive and –negative indicates that a significant proportion of the latter were in
fact HPV 16- associated. The extreme rarity of HPV-negative cancers reinforces the rationale for HPV testing in
addition to, or even instead of, cervical cytology in routine cervical screening.
Cancer Cell lines are the continuous cell lines that keep on dividing under conditions provided in vitro. Primary neoblastic tissues which are abnormal as they keep on dividing are dissociated by enzymatic or enzymatic in combination with chemical or by mechanical disaggregation means.
Depending upon the architecture of the tissue different methodologies are adapted.
The presentation focuses on :-
1. Milestones in cell line research
2. How cancer cell lines are established
3. Method for disaggregation
4. Selective Culture of Tissue Cells
5. Specific Tumor Types - focusing on properties like adherent/suspension and different media provided in the cell lines
6. Problems Associated with Cancer Cell Lines
7. Some Applications
8. References
Integrative Everything, Deep Learning and Streaming DataJoel Saltz
Workshop on Clusters, Clouds, and Data for Scientific Computing, September 6, 2018
The need to create to label information and segment regions in individual sensor data sources and to create synthesizes from multiple disparate data sources span many areas of science, biomedicine and technology. The rapid evolution in sensor technologies – from digital microscopes to UAVs drive requirements in this area. I will describe a variety of use cases, describe technical challenges as well as tools, algorithms and techniques developed by our group and collaborators.
Caffeine against cancer and novel therapies for solid tumorsmajo alvarez
2 recent news that talk about the DNA replication and reparation, the caffeine as a skin cancer preventive agent and the use of PARP inhibitors instead of topotecan in chemotherapy.
OMICS Publishing Group, Journal of Carcinogenesis & Mutagenesis features the critical reviews focused on topics of significant interest to specialists in cancer biology and mutation research, scope of the journal reflects the rapid advances in the field of mutation research and latest developments in gene therapy for cancer.
Different results published in the Journal of the National Comprehensive Cancer Network suggest that neuroendocrine tumour Singapore independently, as per Julie Hallet, MD, FRCSC, MSc, a researcher in the department of surgery in Odette Cancer Centre in Sunnybrook Health Sciences Center, Toronto. Visit @ https://www.novenacancercentre.com/our-specialists/dr-lim-hwee-yong/
Analysis Analysis Analysis Analysisof the entire entire entire protein protein proteinproteincomplementcomplement complement complement of acell, cell, tissue, tissue, tissue, or organism organism organism under under aspecific, specific, specific, defined defined set of conditions conditions conditions .
• Relies Relies Relies on 3basic technological technological technological technological technological cornerstones cornerstones cornerstones cornerstones
• MethodMethod MethodMethod to fractionatefractionate fractionatefractionate fractionatefractionate complexcomplex complex protein/protein/ protein/ protein/ peptide peptide peptidemixturesmixtures mixtures
• MS to acquire acquire the data data necessary necessary to identify identify identifyidentifyindividual individual individual individualproteins proteins
• Bioinformatics Bioinformatics Bioinformatics Bioinformatics Bioinformatics Bioinformatics Bioinformaticsto analyze analyze and assemble assemble the MS data
An understanding towards genetics and epigenetics is essential to cope up with the paradigm shift which is underway. Personalized medicine and gene therapy will confluence the days to come.
This review highlights traditional approaches as well as current advancements in the analysis of the gene expression data from cancer perspective.
Due to improvements in biometric instrumentation and automation, it has become easier to collect a lot of experimental data in molecular biology.
Analysis of such data is extremely important as it leads to knowledge discovery that can be validated by experiments. Previously, the diagnosis of complex genetic diseases has conventionally been done based on the non-molecular characteristics like kind of tumor tissue, pathological characteristics, and clinical phase.
The microarray data can be well accounted for high dimensional space and noise. Same were the reasons for ineffective and imprecise results. Several machine learning and data mining techniques are presently applied for identifying cancer using gene expression data.
While differences in efficiency do exist, none of the well-established approaches is uniformly superior to others. The quality of algorithm is important, but is not in itself a guarantee of the quality of a specific data analysis.
http://kaashivinfotech.com/
http://inplanttrainingchennai.com/
http://inplanttraining-in-chennai.com/
http://internshipinchennai.in/
http://inplant-training.org/
http://kernelmind.com/
http://inplanttraining-in-chennai.com/
http://inplanttrainingchennai.com/
HUMAN PAPILLOMAVIRUS IS A NECESSARY CAUSE OF INVASIVE CERVICAL CANCER WORLD-WIDEAlberto Cuadrado
Infection with oncogenic human papillomavirus (HPV) is the major risk factor in the aetiology of cervical cancer. In a
previous study of invasive cervical cancers collected from 22 countries (the International Biological Study on Cervical
Cancer, IBSCC), however, the PCR assay used failed to detect HPV DNA in 7% of samples. The current study
re-examined these so-called HPV-negative samples, as well as a proportion of the originally positive samples, using a
more stringent procedure to ensure the presence of carcinoma cells within the material used for PCR. In addition,
three different PCR assays targeting different open reading frames were used, to avoid misclassifying as negative
samples in which integration of HPV DNA had led to disruption of the PCR primer sequences or loss of the HPV L1
open reading frame, the target of the PCR assay used in the original study. Furthermore, sera from the patients
originally classified as HPV-negative were assayed for antibodies against viral-like particles (VLPs) and E6 and E7
proteins of HPV 16, which accounts for about 50% of HPV-positive cervical cancers world-wide.
Of those serum samples tested, antibodies to at least one HPV 16 protein were detected in a similar proportion of
those originally classified as HPV-negative or -positive: 56% and 67%, respectively. There was no significant difference
between the two groups in the proportion of antibodies reactive to VLPs, E6 or E7. After excluding histologically
inadequate samples (87%), only 6% of those initially classified as HPV-negative remained negative to all the PCR
assays used for retesting. Thus the true incidence of HPV-positive samples in the IBSCC is 99.7%.
Most of the HPV-negative samples in the earlier study proved to have been misclassified since a more stringent
testing procedure revealed them to be HPV-positive. The similarity of the serum antibody profiles from patients with
cancers originally classified as HPV-positive and –negative indicates that a significant proportion of the latter were in
fact HPV 16- associated. The extreme rarity of HPV-negative cancers reinforces the rationale for HPV testing in
addition to, or even instead of, cervical cytology in routine cervical screening.
Cancer Cell lines are the continuous cell lines that keep on dividing under conditions provided in vitro. Primary neoblastic tissues which are abnormal as they keep on dividing are dissociated by enzymatic or enzymatic in combination with chemical or by mechanical disaggregation means.
Depending upon the architecture of the tissue different methodologies are adapted.
The presentation focuses on :-
1. Milestones in cell line research
2. How cancer cell lines are established
3. Method for disaggregation
4. Selective Culture of Tissue Cells
5. Specific Tumor Types - focusing on properties like adherent/suspension and different media provided in the cell lines
6. Problems Associated with Cancer Cell Lines
7. Some Applications
8. References
Integrative Everything, Deep Learning and Streaming DataJoel Saltz
Workshop on Clusters, Clouds, and Data for Scientific Computing, September 6, 2018
The need to create to label information and segment regions in individual sensor data sources and to create synthesizes from multiple disparate data sources span many areas of science, biomedicine and technology. The rapid evolution in sensor technologies – from digital microscopes to UAVs drive requirements in this area. I will describe a variety of use cases, describe technical challenges as well as tools, algorithms and techniques developed by our group and collaborators.
Caffeine against cancer and novel therapies for solid tumorsmajo alvarez
2 recent news that talk about the DNA replication and reparation, the caffeine as a skin cancer preventive agent and the use of PARP inhibitors instead of topotecan in chemotherapy.
OMICS Publishing Group, Journal of Carcinogenesis & Mutagenesis features the critical reviews focused on topics of significant interest to specialists in cancer biology and mutation research, scope of the journal reflects the rapid advances in the field of mutation research and latest developments in gene therapy for cancer.
Different results published in the Journal of the National Comprehensive Cancer Network suggest that neuroendocrine tumour Singapore independently, as per Julie Hallet, MD, FRCSC, MSc, a researcher in the department of surgery in Odette Cancer Centre in Sunnybrook Health Sciences Center, Toronto. Visit @ https://www.novenacancercentre.com/our-specialists/dr-lim-hwee-yong/
Circulating Tumor Cells and Cell-Free Nucleic Acids as Predictor Factors for ...daranisaha
Pancreatic cancer remains as one of the most aggressive and deadliest of cancers largely due to formidable challenges in diagnosis and therapy. Consensus standard treatment for patients with nonmetastatic Pancreatic Cancer (PC) incorporates possible neoadjuvant chemotherapy with timely surgical resection and adjuvant chemotherapy. However, despite all the sophistication of modern radiological and endoscopic techniques, the decision regarding operability is often only made intra-operatively, therefore subjecting a patient to unnecessary surgical intervention, and postponing the possibility of starting early chemotherapy.
Circulating Tumor Cells and Cell-Free Nucleic Acids as Predictor Factors for ...AnonIshanvi
Pancreatic cancer remains as one of the most aggressive and deadliest of cancers largely due to formidable challenges in diagnosis and therapy. Consensus standard treatment for patients with nonmetastatic Pancreatic Cancer (PC) incorporates possible neoadjuvant chemotherapy with timely surgical resection and adjuvant chemotherapy. However, despite all the sophistication of modern radiological and endoscopic techniques, the decision regarding operability is often only made intra-operatively, therefore subjecting a patient to unnecessary surgical intervention, and postponing the possibility of starting early chemotherapy.
Circulating Tumor Cells and Cell-Free Nucleic Acids as Predictor Factors for ...JohnJulie1
Pancreatic cancer remains as one of the most aggressive and deadliest of cancers largely due to formidable challenges in diagnosis and therapy. Consensus standard treatment for patients with nonmetastatic Pancreatic Cancer (PC) incorporates possible neoadjuvant chemotherapy with timely surgical resection and adjuvant chemotherapy. However, despite all the sophistication of modern radiological and endoscopic techniques, the decision regarding operability is often only made intra-operatively, therefore subjecting a patient to unnecessary surgical intervention, and postponing the possibility of starting early chemotherapy.
Circulating Tumor Cells and Cell-Free Nucleic Acids as Predictor Factors for ...semualkaira
Pancreatic cancer remains as one of the most
aggressive and deadliest of cancers largely due to formidable challenges in diagnosis and therapy. Consensus standard treatment for
patients with nonmetastatic Pancreatic Cancer (PC) incorporates
possible neoadjuvant chemotherapy with timely surgical resection
and adjuvant chemotherapy. However, despite all the sophistication of modern radiological and endoscopic techniques, the decision regarding operability is often only made intra-operatively,
therefore subjecting a patient to unnecessary surgical intervention,
and postponing the possibility of starting early chemotherapy.
Circulating Tumor Cells and Cell-Free Nucleic Acids as Predictor Factors for ...EditorSara
Pancreatic cancer remains as one of the most aggressive and deadliest of cancers largely due to formidable challenges in diagnosis and therapy. Consensus standard treatment for patients with nonmetastatic Pancreatic Cancer (PC) incorporates possible neoadjuvant chemotherapy with timely surgical resection and adjuvant chemotherapy. However, despite all the sophistication of modern radiological and endoscopic techniques, the decision regarding operability is often only made intra-operatively, therefore subjecting a patient to unnecessary surgical intervention, and postponing the possibility of starting early chemotherapy.
Circulating Tumor Cells and Cell-Free Nucleic Acids as Predictor Factors for ...EditorSara
Pancreatic cancer remains as one of the most aggressive and deadliest of cancers largely due to formidable challenges in diagnosis and therapy. Consensus standard treatment for patients with nonmetastatic Pancreatic Cancer (PC) incorporates possible neoadjuvant chemotherapy with timely surgical resection and adjuvant chemotherapy. However, despite all the sophistication of modern radiological and endoscopic techniques, the decision regarding operability is often only made intra-operatively, therefore subjecting a patient to unnecessary surgical intervention, and postponing the possibility of starting early chemotherapy.
Circulating Tumor Cells and Cell-Free Nucleic Acids as Predictor Factors for ...semualkaira
Pancreatic cancer remains as one of the most
aggressive and deadliest of cancers largely due to formidable challenges in diagnosis and therapy. Consensus standard treatment for
patients with nonmetastatic Pancreatic Cancer (PC) incorporates
possible neoadjuvant chemotherapy with timely surgical resection
and adjuvant chemotherapy
Circulating Tumor Cells and Cell-Free Nucleic Acids as Predictor Factors for ...semualkaira
Pancreatic cancer remains as one of the most aggressive and deadliest of cancers largely due to formidable challenges in diagnosis and therapy. Consensus standard treatment for patients with nonmetastatic Pancreatic Cancer (PC) incorporates possible neoadjuvant chemotherapy with timely surgical resection and adjuvant chemotherapy. However, despite all the sophistication of modern radiological and endoscopic techniques, the decision regarding operability is often only made intra-operatively, therefore subjecting a patient to unnecessary surgical intervention, and postponing the possibility of starting early chemotherapy.
Circulating Tumor Cells and Cell-Free Nucleic Acids as Predictor Factors for ...NainaAnon
Pancreatic cancer remains as one of the most aggressive and deadliest of cancers largely due to formidable challenges in diagnosis and therapy. Consensus standard treatment for patients with nonmetastatic Pancreatic Cancer (PC) incorporates possible neoadjuvant chemotherapy with timely surgical resection and adjuvant chemotherapy. However, despite all the sophistication of modern radiological and endoscopic techniques, the decision regarding operability is often only made intra-operatively, therefore subjecting a patient to unnecessary surgical intervention, and postponing the possibility of starting early chemotherapy.
Circulating Tumor Cells and Cell-Free Nucleic Acids as Predictor Factors for ...semualkaira
Pancreatic cancer remains as one of the most
aggressive and deadliest of cancers largely due to formidable challenges in diagnosis and therapy. Consensus standard treatment for
patients with nonmetastatic Pancreatic Cancer (PC) incorporates
possible neoadjuvant chemotherapy with timely surgical resection
and adjuvant chemotherapy
SAP Sapphire 2024 - ASUG301 building better apps with SAP Fiori.pdfPeter Spielvogel
Building better applications for business users with SAP Fiori.
• What is SAP Fiori and why it matters to you
• How a better user experience drives measurable business benefits
• How to get started with SAP Fiori today
• How SAP Fiori elements accelerates application development
• How SAP Build Code includes SAP Fiori tools and other generative artificial intelligence capabilities
• How SAP Fiori paves the way for using AI in SAP apps
LF Energy Webinar: Electrical Grid Modelling and Simulation Through PowSyBl -...DanBrown980551
Do you want to learn how to model and simulate an electrical network from scratch in under an hour?
Then welcome to this PowSyBl workshop, hosted by Rte, the French Transmission System Operator (TSO)!
During the webinar, you will discover the PowSyBl ecosystem as well as handle and study an electrical network through an interactive Python notebook.
PowSyBl is an open source project hosted by LF Energy, which offers a comprehensive set of features for electrical grid modelling and simulation. Among other advanced features, PowSyBl provides:
- A fully editable and extendable library for grid component modelling;
- Visualization tools to display your network;
- Grid simulation tools, such as power flows, security analyses (with or without remedial actions) and sensitivity analyses;
The framework is mostly written in Java, with a Python binding so that Python developers can access PowSyBl functionalities as well.
What you will learn during the webinar:
- For beginners: discover PowSyBl's functionalities through a quick general presentation and the notebook, without needing any expert coding skills;
- For advanced developers: master the skills to efficiently apply PowSyBl functionalities to your real-world scenarios.
Accelerate your Kubernetes clusters with Varnish CachingThijs Feryn
A presentation about the usage and availability of Varnish on Kubernetes. This talk explores the capabilities of Varnish caching and shows how to use the Varnish Helm chart to deploy it to Kubernetes.
This presentation was delivered at K8SUG Singapore. See https://feryn.eu/presentations/accelerate-your-kubernetes-clusters-with-varnish-caching-k8sug-singapore-28-2024 for more details.
Elevating Tactical DDD Patterns Through Object CalisthenicsDorra BARTAGUIZ
After immersing yourself in the blue book and its red counterpart, attending DDD-focused conferences, and applying tactical patterns, you're left with a crucial question: How do I ensure my design is effective? Tactical patterns within Domain-Driven Design (DDD) serve as guiding principles for creating clear and manageable domain models. However, achieving success with these patterns requires additional guidance. Interestingly, we've observed that a set of constraints initially designed for training purposes remarkably aligns with effective pattern implementation, offering a more ‘mechanical’ approach. Let's explore together how Object Calisthenics can elevate the design of your tactical DDD patterns, offering concrete help for those venturing into DDD for the first time!
Smart TV Buyer Insights Survey 2024 by 91mobiles.pdf91mobiles
91mobiles recently conducted a Smart TV Buyer Insights Survey in which we asked over 3,000 respondents about the TV they own, aspects they look at on a new TV, and their TV buying preferences.
Key Trends Shaping the Future of Infrastructure.pdfCheryl Hung
Keynote at DIGIT West Expo, Glasgow on 29 May 2024.
Cheryl Hung, ochery.com
Sr Director, Infrastructure Ecosystem, Arm.
The key trends across hardware, cloud and open-source; exploring how these areas are likely to mature and develop over the short and long-term, and then considering how organisations can position themselves to adapt and thrive.
Welocme to ViralQR, your best QR code generator.ViralQR
Welcome to ViralQR, your best QR code generator available on the market!
At ViralQR, we design static and dynamic QR codes. Our mission is to make business operations easier and customer engagement more powerful through the use of QR technology. Be it a small-scale business or a huge enterprise, our easy-to-use platform provides multiple choices that can be tailored according to your company's branding and marketing strategies.
Our Vision
We are here to make the process of creating QR codes easy and smooth, thus enhancing customer interaction and making business more fluid. We very strongly believe in the ability of QR codes to change the world for businesses in their interaction with customers and are set on making that technology accessible and usable far and wide.
Our Achievements
Ever since its inception, we have successfully served many clients by offering QR codes in their marketing, service delivery, and collection of feedback across various industries. Our platform has been recognized for its ease of use and amazing features, which helped a business to make QR codes.
Our Services
At ViralQR, here is a comprehensive suite of services that caters to your very needs:
Static QR Codes: Create free static QR codes. These QR codes are able to store significant information such as URLs, vCards, plain text, emails and SMS, Wi-Fi credentials, and Bitcoin addresses.
Dynamic QR codes: These also have all the advanced features but are subscription-based. They can directly link to PDF files, images, micro-landing pages, social accounts, review forms, business pages, and applications. In addition, they can be branded with CTAs, frames, patterns, colors, and logos to enhance your branding.
Pricing and Packages
Additionally, there is a 14-day free offer to ViralQR, which is an exceptional opportunity for new users to take a feel of this platform. One can easily subscribe from there and experience the full dynamic of using QR codes. The subscription plans are not only meant for business; they are priced very flexibly so that literally every business could afford to benefit from our service.
Why choose us?
ViralQR will provide services for marketing, advertising, catering, retail, and the like. The QR codes can be posted on fliers, packaging, merchandise, and banners, as well as to substitute for cash and cards in a restaurant or coffee shop. With QR codes integrated into your business, improve customer engagement and streamline operations.
Comprehensive Analytics
Subscribers of ViralQR receive detailed analytics and tracking tools in light of having a view of the core values of QR code performance. Our analytics dashboard shows aggregate views and unique views, as well as detailed information about each impression, including time, device, browser, and estimated location by city and country.
So, thank you for choosing ViralQR; we have an offer of nothing but the best in terms of QR code services to meet business diversity!
Transcript: Selling digital books in 2024: Insights from industry leaders - T...BookNet Canada
The publishing industry has been selling digital audiobooks and ebooks for over a decade and has found its groove. What’s changed? What has stayed the same? Where do we go from here? Join a group of leading sales peers from across the industry for a conversation about the lessons learned since the popularization of digital books, best practices, digital book supply chain management, and more.
Link to video recording: https://bnctechforum.ca/sessions/selling-digital-books-in-2024-insights-from-industry-leaders/
Presented by BookNet Canada on May 28, 2024, with support from the Department of Canadian Heritage.
Generative AI Deep Dive: Advancing from Proof of Concept to ProductionAggregage
Join Maher Hanafi, VP of Engineering at Betterworks, in this new session where he'll share a practical framework to transform Gen AI prototypes into impactful products! He'll delve into the complexities of data collection and management, model selection and optimization, and ensuring security, scalability, and responsible use.
Observability Concepts EVERY Developer Should Know -- DeveloperWeek Europe.pdfPaige Cruz
Monitoring and observability aren’t traditionally found in software curriculums and many of us cobble this knowledge together from whatever vendor or ecosystem we were first introduced to and whatever is a part of your current company’s observability stack.
While the dev and ops silo continues to crumble….many organizations still relegate monitoring & observability as the purview of ops, infra and SRE teams. This is a mistake - achieving a highly observable system requires collaboration up and down the stack.
I, a former op, would like to extend an invitation to all application developers to join the observability party will share these foundational concepts to build on:
A tale of scale & speed: How the US Navy is enabling software delivery from l...sonjaschweigert1
Rapid and secure feature delivery is a goal across every application team and every branch of the DoD. The Navy’s DevSecOps platform, Party Barge, has achieved:
- Reduction in onboarding time from 5 weeks to 1 day
- Improved developer experience and productivity through actionable findings and reduction of false positives
- Maintenance of superior security standards and inherent policy enforcement with Authorization to Operate (ATO)
Development teams can ship efficiently and ensure applications are cyber ready for Navy Authorizing Officials (AOs). In this webinar, Sigma Defense and Anchore will give attendees a look behind the scenes and demo secure pipeline automation and security artifacts that speed up application ATO and time to production.
We will cover:
- How to remove silos in DevSecOps
- How to build efficient development pipeline roles and component templates
- How to deliver security artifacts that matter for ATO’s (SBOMs, vulnerability reports, and policy evidence)
- How to streamline operations with automated policy checks on container images
GraphRAG is All You need? LLM & Knowledge GraphGuy Korland
Guy Korland, CEO and Co-founder of FalkorDB, will review two articles on the integration of language models with knowledge graphs.
1. Unifying Large Language Models and Knowledge Graphs: A Roadmap.
https://arxiv.org/abs/2306.08302
2. Microsoft Research's GraphRAG paper and a review paper on various uses of knowledge graphs:
https://www.microsoft.com/en-us/research/blog/graphrag-unlocking-llm-discovery-on-narrative-private-data/
Builder.ai Founder Sachin Dev Duggal's Strategic Approach to Create an Innova...Ramesh Iyer
In today's fast-changing business world, Companies that adapt and embrace new ideas often need help to keep up with the competition. However, fostering a culture of innovation takes much work. It takes vision, leadership and willingness to take risks in the right proportion. Sachin Dev Duggal, co-founder of Builder.ai, has perfected the art of this balance, creating a company culture where creativity and growth are nurtured at each stage.
Builder.ai Founder Sachin Dev Duggal's Strategic Approach to Create an Innova...
Leiddy reflection
1. Nicole Colón
Seminar Reflections:
According to Vincent A. et al in the article “Early detection of Recurrent Brest Cancer Using
Metabolite Profiling” brest cancer is one of the leading causes of death between women. Recent studies
have proved that early detection of breast cancer can increase the survival of the affected person. It’s said
that using common methods for detecting this types of cancer, such as mammography and blood tests,
may not be sensitive enough. This study focus on detecting brest cancer by using “Metabolite Profiling”.
Metabolimic is study of chemical processes involving metabolites. To detect this kind of molecule two
main techniques are used: NMR and MS.
Nuclear Magnetic Resonance involved the manipulation of nuclear spin of an atom while Mass
spectrometry separates and detect mass of protein found in the tissue. Using a combination of both
techniques, NMR and MS, leads scientist to a more sensitive and specific biomarkers. During the
detection of these biomarkers serum samples are collected; this samples are put through the two main
techniques, NMR and MS. The data obtain is used to performed statistical analysis and “putative
biomarkers” are identify. These putative biomarkers are validated through two methods: Supervised
method and unsupervised method. Unsupervised methods detect clusters while the supervised method
determines whether the disease is present or not. This article provides the scientific world information
about other methods that can be very useful in the detection of these diseases, such as brest cancer. Using
this kind of methods can be dramatically significant to the scientific world involved in cancer studies. It
can be applied to daily use and can increase the survival of the affected persons.
