Dave McClure is a founding partner at 500 Startups, a global seed fund and startup accelerator. He discusses 500 Startups' strategy of making lots of small bets across many early-stage startups, expecting most to fail but some to become large exits. McClure outlines 500 Startups' investment process and criteria at different stages, from initial product validation and customer usage testing to revenue validation and growth. He emphasizes focusing on product-market fit and real customer usage over business plans and market projections. McClure also discusses tracking investment performance, when to double down on investments, and estimates the potential size of the global seed-stage startup market.