London, May 28, 2009
Kenny De Meirleir (1), Chris Roelant (2), Marc Fremont (2), Kristin Metzger (2), Henry Butt (3)
(1) Vrije Universiteit Brussel & HIMMUNITAS foundation, Brussels, Belgium
(2) Protea BioPharma, Brussels, Belgium
(3) Bioscreen & Bio 21, University of Melbourne, Melbourne, Australia
The document discusses digestive well-being and probiotics. It begins with an introduction to the topic, noting that one-third to one-half of the population suffers from digestive illnesses related to diet and lifestyle. It then covers the roles of probiotics and normal gut flora in supporting metabolic processes, epithelial cell differentiation, and pathogen protection. Probiotics, including lactobacilli and bifidobacteria, are live microorganisms that can beneficially affect the host by improving gut microbial balance. Prebiotics are non-digestible foods that stimulate the growth of beneficial bacteria. Clinical studies have shown probiotics may help maintain optimal mucosal barrier function and balance intestinal flora.
This document discusses the use of probiotics in the neonatal intensive care unit (NICU) to help prevent diseases like necrotizing enterocolitis (NEC). It provides background on the development of the infant gut microbiome and how probiotics may benefit preterm infants by competing with pathogens, producing antimicrobial substances, and modulating the immune system. Several studies cited found probiotic supplementation significantly reduced the risk of NEC and mortality in very low birth weight infants. Meta-analyses support the routine use of probiotics in the NICU.
This document discusses probiotics and their role in health and disease. It provides an overview of the growing probiotic market and increasing scientific interest in probiotics. Some key points include:
- Probiotics are live microorganisms that may provide health benefits when consumed. Common probiotic strains include Lactobacillus and Bifidobacterium.
- Probiotics may provide benefits through interactions with the gut microbiota and potential mechanisms like immune modulation.
- Research on probiotics has focused on conditions like diarrhea, IBS, ulcerative colitis, and H. pylori infection, among others. Effects appear to be strain-specific.
- Quality control factors like viability and accurate labeling of dose
Dannon probiotic yogurt contains beneficial bacteria like Bifidobacterium lactis that can aid digestion when consumed daily. These probiotics survive the gastrointestinal system and establish themselves in the intestines to provide effects like supporting the immune system and digestive health. Dannon yogurt provides over 1 billion live, active strains of B. lactis per serving along with Lactobacillus bulgaricus and Streptococcus thermophilus. It works by delivering probiotics to the intestines alive where they can confer benefits. Probiotics from food provide nutrients not found in supplements, though supplements contain higher bacteria counts. Both sources can be beneficial when combined with a balanced diet and lifestyle.
1. The document discusses gut microflora and its role in susceptibility of lepidopteran pests to Bacillus thuringiensis (Bt). It covers types of insect-microbe interactions like pathogenic, symbiotic, and their characteristics.
2. Methods for analyzing gut microflora diversity are described, including gene targeting, molecular fingerprinting, fluorescent in situ hybridization, and metagenomics. Studies on the diversity of gut microflora in various lepidopterans are presented.
3. The role of gut microflora in influencing Bt susceptibility is explored through case studies on enzymes, siderophores, competition with pathogens, and synergistic activity with Bt. The document concludes
Dr. Shikhman discusses reasons why you still may not feel well even after going gluten free. Covering leaky gut syndrome, yeast overgrowth, food allergies, endocrine abnormalities.
Probiotics are live microorganisms that provide health benefits when consumed. The root word means "for life" and they promote gut health by regulating microflora balance. Common probiotic bacteria include Lactobacillus, Bifidobacterium, and Saccharomyces. Food sources include yogurt, kefir, kimchi and they are also available as supplements. Research shows probiotics may help treat conditions like diarrhea, IBS, eczema and H. pylori infections by competing with pathogens and strengthening gut immunity. More studies are still needed to better understand probiotic strains, efficacy and applications in new products.
Pre and probiotics in colorectal cancer Prevention By Dalia Khamis El-DeebDalia Deeb
This document discusses prebiotics, probiotics, and their potential role in preventing colon cancer. It begins with definitions of prebiotics as selectively fermented ingredients that change the gastrointestinal microflora to benefit health. Probiotics are live microorganisms that colonize the intestines and exert beneficial effects. The document explores how gut microbiota can contribute to carcinogenesis and the mechanisms by which probiotics and their short-chain fatty acid products may prevent colon cancer, such as decreasing pH, modulating compounds, and inducing apoptosis in altered cells. It concludes that while studies have shown potential, more research is still needed to fully understand mechanisms and generate conclusive evidence on using prebiotics and probiotics to prevent and manage colon
The document discusses digestive well-being and probiotics. It begins with an introduction to the topic, noting that one-third to one-half of the population suffers from digestive illnesses related to diet and lifestyle. It then covers the roles of probiotics and normal gut flora in supporting metabolic processes, epithelial cell differentiation, and pathogen protection. Probiotics, including lactobacilli and bifidobacteria, are live microorganisms that can beneficially affect the host by improving gut microbial balance. Prebiotics are non-digestible foods that stimulate the growth of beneficial bacteria. Clinical studies have shown probiotics may help maintain optimal mucosal barrier function and balance intestinal flora.
This document discusses the use of probiotics in the neonatal intensive care unit (NICU) to help prevent diseases like necrotizing enterocolitis (NEC). It provides background on the development of the infant gut microbiome and how probiotics may benefit preterm infants by competing with pathogens, producing antimicrobial substances, and modulating the immune system. Several studies cited found probiotic supplementation significantly reduced the risk of NEC and mortality in very low birth weight infants. Meta-analyses support the routine use of probiotics in the NICU.
This document discusses probiotics and their role in health and disease. It provides an overview of the growing probiotic market and increasing scientific interest in probiotics. Some key points include:
- Probiotics are live microorganisms that may provide health benefits when consumed. Common probiotic strains include Lactobacillus and Bifidobacterium.
- Probiotics may provide benefits through interactions with the gut microbiota and potential mechanisms like immune modulation.
- Research on probiotics has focused on conditions like diarrhea, IBS, ulcerative colitis, and H. pylori infection, among others. Effects appear to be strain-specific.
- Quality control factors like viability and accurate labeling of dose
Dannon probiotic yogurt contains beneficial bacteria like Bifidobacterium lactis that can aid digestion when consumed daily. These probiotics survive the gastrointestinal system and establish themselves in the intestines to provide effects like supporting the immune system and digestive health. Dannon yogurt provides over 1 billion live, active strains of B. lactis per serving along with Lactobacillus bulgaricus and Streptococcus thermophilus. It works by delivering probiotics to the intestines alive where they can confer benefits. Probiotics from food provide nutrients not found in supplements, though supplements contain higher bacteria counts. Both sources can be beneficial when combined with a balanced diet and lifestyle.
1. The document discusses gut microflora and its role in susceptibility of lepidopteran pests to Bacillus thuringiensis (Bt). It covers types of insect-microbe interactions like pathogenic, symbiotic, and their characteristics.
2. Methods for analyzing gut microflora diversity are described, including gene targeting, molecular fingerprinting, fluorescent in situ hybridization, and metagenomics. Studies on the diversity of gut microflora in various lepidopterans are presented.
3. The role of gut microflora in influencing Bt susceptibility is explored through case studies on enzymes, siderophores, competition with pathogens, and synergistic activity with Bt. The document concludes
Dr. Shikhman discusses reasons why you still may not feel well even after going gluten free. Covering leaky gut syndrome, yeast overgrowth, food allergies, endocrine abnormalities.
Probiotics are live microorganisms that provide health benefits when consumed. The root word means "for life" and they promote gut health by regulating microflora balance. Common probiotic bacteria include Lactobacillus, Bifidobacterium, and Saccharomyces. Food sources include yogurt, kefir, kimchi and they are also available as supplements. Research shows probiotics may help treat conditions like diarrhea, IBS, eczema and H. pylori infections by competing with pathogens and strengthening gut immunity. More studies are still needed to better understand probiotic strains, efficacy and applications in new products.
Pre and probiotics in colorectal cancer Prevention By Dalia Khamis El-DeebDalia Deeb
This document discusses prebiotics, probiotics, and their potential role in preventing colon cancer. It begins with definitions of prebiotics as selectively fermented ingredients that change the gastrointestinal microflora to benefit health. Probiotics are live microorganisms that colonize the intestines and exert beneficial effects. The document explores how gut microbiota can contribute to carcinogenesis and the mechanisms by which probiotics and their short-chain fatty acid products may prevent colon cancer, such as decreasing pH, modulating compounds, and inducing apoptosis in altered cells. It concludes that while studies have shown potential, more research is still needed to fully understand mechanisms and generate conclusive evidence on using prebiotics and probiotics to prevent and manage colon
Probiotics are live microorganisms that, when consumed in adequate amounts, confer health benefits. The document defines probiotics according to the FAO and WHO as live microorganisms that benefit the host. Common probiotic bacteria include Lactobacilli and Bifidobacteria, which are found naturally in the gut microbiota. Potential health benefits of probiotics may depend on the specific strains consumed.
Ankylosing Spondylitis the gut and the bugs: an integrative approach to treat...IFSMED
The document discusses the relationship between ankylosing spondylitis and gut health. It notes that subclinical gut inflammation is present in many spondyloarthropathy patients. Two types of gut inflammation are described - acute and chronic. The chronic type resembles Crohn's disease. Increased intestinal permeability is a key mechanism in spondyloarthropathis. Tight junctions regulate permeability and zonulin modulates this. The document discusses optimizing gut microbiota and permeability through probiotics, prebiotics, diet and supplements to help treat spondyloarthropathis through a gut-focused approach.
Probiotics are well known and routinely used additives in the main livestock species. They claim to improve gut health by stabilising gut flora being their effect reflected in a better overall health status, welfare and performance of the animals.
Probiotics are live microorganisms that support gut health. The gut contains 70% of the immune system, making a balanced gut microbiome important. Probiotics may be useful when medication, illness, stress, travel, or aging disrupt the balance of good and bad bacteria. Imbalances can cause issues like IBS, bloating, constipation or diarrhea. The document recommends probiotics containing multiple strains of bacteria or yeast, and highlights three probiotic supplements from Specialist Supplements containing different formulations to support gut health.
The document discusses probiotics, prebiotics, and synbiotics. It defines them as follows:
- Probiotics are live microorganisms that confer health benefits when consumed. They include bacteria like Lactobacillus and Bifidobacterium.
- Prebiotics are non-digestible food ingredients that promote the growth of beneficial bacteria. They include fibers like inulin and oligosaccharides.
- Synbiotics refer to products containing both probiotics and prebiotics to help probiotics survive and colonize the gut.
Probiotics, prebiotics, and synbiotics were defined. Probiotics are live microorganisms that provide health benefits when consumed. Prebiotics are non-digestible fibers that promote the growth of beneficial bacteria. Synbiotics combine probiotics and prebiotics. The document discussed the history of probiotic research from Metchnikoff's observations of Bulgarian longevity to current probiotic foods and strains. Potential health benefits of probiotics include managing diarrhea, allergies, and cholesterol, as well as supporting the immune system. Factors like processing, storage and the host's health impact probiotic survival.
The storyline behind the modern epidemic of inflammation driven disease goes as follows:
• Chronic degenerative conditions (Diseases of Civilization – DOCs) are on the rise and have overtaken infections as the major source of death and illness.
• This epidemiological transition is due, at least in part, to environmental changes that have increased the disease liability of genetic profiles that were previously benign.
• These DOCs are associated with increased systemic inflammation stemming from inappropriate stressor-response mechanisms.
• Much of this inflammation is generated and/or perpetuated by the gut-brain axis.
• Gut-brain axis derived inflammation leads to disruptions in psycho-neuro-immunological (PNI) balances.
• Pathophysiological mediators of PNI disturbances can be measured and treated.
• A cornerstone of said treatment is the regular consumption of a high quality multi-strain probiotic.
The carefully selected strains in Tri-Flora have been shown to:
• Decrease pro-inflammatory cytokines;
• Increase anti-inflammatory cytokine IL-10;
• Stimulate regulatory immune cells;
• Inhibit immune response to LPS (lipopolysaccharide) transduction;
• Improve intestinal barrier function;
• Enhance mucosal and systemic immune responses;
• Produce and deliver neurotransmitters such as GABA and serotonin.
And in so doing accomplish some very intriguing clinical feats:
1. Lessen symptoms of chronic fatigue syndrome;
2. Act as an adjunct to standard care in the treatment of Major Depressive Disorder;
3. Improve anxiety and reduce brain cell death; and
4. Help women lose weight.
It is for reasons such as this, that my most commonly recommended supplement for most people is a high quality probiotic. Tri-Flora by IP Formulas is my new favorite.
Get started today with the Gut flora & probiotic 11 to enjoy good health and a 15% discount...:0)
Simply, copy and paste the link below at your web browser address barpelase visit the l
http://totalhealthnow.eu.nspshop.com/probiotic_eleven_%2890%29.htm
>Since the ban of antibiotic growth promoters (AGPs) in the European Union, the industry has been looking for valid alternatives to improve health, immune status and performance in animal agriculture.
>The industry focuses on developing solutions that mimic the effects of AGPs. However, the exact mode of action of the AGPs to improve poultry performance is not fully understood.
Most AGPs alternatives try to prevent the proliferation of pathogenic bacteria and to modulate indigenous bacteria to improve immune status and performance.
>As an industry, we have made limited progress in improving gut health. Maybe we need to change the approach to find the most optimal solution.
>As part of a stable ecological system, pathogens per se do not represent a threat to animal health. The dynamic nature of the gastrointestinal microflora in chickens makes maintaining the right balance in the microbial ecosystem.
>Despite a large amount of scientific work has been done on the topic, a lack of consistent improvement has been registered.
>To improve gut health more consistently, a broader approach, involving a combination of nutrition, feed technology and husbandry management needs to be taken.
>In addition, gut-health is too complex to be solved from
only one point of view. Input should be obtained from different disciplines, including food technology, human nutrition, veterinary and human medical sciences.
>DSM will start an holistic program to come to tailor made solutions to improve the gut ecosystem with the objective of reducing the use of antibiotics in the poultry industry.
The document discusses how to choose a probiotic supplement. Key factors include choosing strains that are beneficial for your specific needs, selecting a probiotic that is effective for the desired health benefits, and choosing ones that are safe, acid/bile resistant, and reliably deliver live cultures. The document recommends considering strain origin, ability to colonize the gut, and individual dietary needs or preferences when selecting a probiotic supplement.
Leaky gut syndrome occurs when the intestines become porous, allowing undigested toxins and particles to pass through the intestinal wall. Maintaining a balance of good and bad bacteria in the gut is important for digestive and immune health. Probiotics can help treat leaky gut by repairing the intestinal lining and rebalancing gut bacteria. Studies show certain probiotic strains like Lactobacillus help improve leaky gut symptoms and intestinal permeability. The document recommends probiotic supplements containing multiple billion live cells of various tested strains to most effectively treat leaky gut.
The document summarizes an annual probiotic symposium held in Chennai, India in December 2016. It includes the following:
- An agenda for the symposium that covers definitions of probiotics, prebiotics, and synbiotics; the history of probiotics; the role of probiotics in gastrointestinal diseases; their functions and mechanisms of action; clinical applications in gastroenterology; dosage and safety issues; and conclusions.
- Presentations on the topics of probiotics in gastrointestinal diseases, their equilibrium in nature and the human body, and the gut flora.
- Evidence that certain probiotic strains like Lactobacillus and Bifidobacterium can reduce disease activity and symptoms
Many are confused what is the difference between prebiotics and probiotics. They are always surprised when they find out that they are completely different, but they complement each other very well.
Kefir contains more probiotic strains and a higher concentration of probiotics than yogurt. Kefir typically contains around 40 billion probiotic organisms per half cup serving, while Greek yogurt contains around 60 million CFU per gram. The probiotics in kefir are also more likely to colonize the intestines long-term compared to the transient bacteria in yogurt. However, both kefir and yogurt provide health benefits by maintaining digestive health and balancing intestinal microflora.
prebiotic and probiotic....., diffrent between prebiotic and probiotic , in food chemistry , and also food processing tecnology, A.D patel institute of tecnology, v.v nagar, gujrat,india,
Herbana Red Goji Juice Concentrate (Slideshare)guest33a24e
The document discusses the purported health benefits of goji berries, inulin fiber, chlorella, and moringa. It claims that goji berries improve eyesight, hair, libido, mood, sleep, energy levels and contain various minerals and amino acids. It also discusses how inulin fiber is a prebiotic that promotes the growth of healthy gut bacteria and may reduce cancer and cholesterol risks. Chlorella is claimed to help fight cancer and boost immunity. Moringa is said to prevent over 300 diseases and have anti-aging, antioxidant and general wellness benefits.
The document discusses the importance of gut microbiota and microbial diversity in gut health and disease. It notes that the gut is home to trillions of microorganisms that play a vital role in digestion, immunity, and overall health. A balanced gut microbiota supports digestive health, but disruptions to this balance through factors like antibiotics, poor diet, pollution, and stress can lead to gut dysbiosis and conditions like leaky gut syndrome. Maintaining a healthy gut microbiota through a fiber-rich diet, limiting sugars and processed foods, taking probiotics, and avoiding overuse of antibiotics is key for overall wellness.
The document discusses the health benefits of probiotic foods. It begins with a brief history of probiotics and defines them as live microorganisms that benefit the host. Probiotics can establish a healthy gut flora, produce antimicrobial substances, and boost immunity. They help treat conditions like antibiotic-associated diarrhea, hepatic encephalopathy, and H. pylori infections. The document examines the selection of probiotic strains and establishes their role in supporting digestive and overall health.
Probiotics are living microorganisms that provide health benefits when consumed in adequate amounts. They help maintain a healthy balance of bacteria in the gut and can aid in digestion, strengthen the immune system, and reduce risks of certain diseases. Common probiotic strains include Lactobacillus and Bifidobacterium species. Probiotics are available in foods like yogurt as well as supplements like tablets and capsules. Consuming probiotics may benefit those with digestive issues, weak immune systems, or frequent infections.
Probiotics- unfolding their potential in boosting poultry industryX S
Definition:
“Living microorganisms when conferred in sufficient amount on the host, will render beneficial effects on health.”(FAO/WHO)
Lactobacillus, Candida, Streptococcus, Enterococcus, Bifidobacterium, Aspergillus, and Saccharomyces spp.
History
Élie Metchnikoff (20th century)
Werner Kolath(1953)
Probiotics for poultry
Need of Probiotics?
Selection criteria
Probiotics in poultry industry
First decisive incident
Commercial vs. wild chicken
Selection criteria
Probiotic requirement in poultry (concept)
How probiotics act?
Maintain normal intestinal microflora
competitive exclusion and resistance
Change metabolism
speeding digestive enzyme activity
Perk up feed intake and digestion
Diminish bacterial enzyme activity and ammonia production
Stimulate the immune system
Evaluation of probiotics on poultry
Growth performance
Intestinal microbiota and morphology
Immune response
Meat quality/chicken caracass
Side effects(toxicity of ingredients)
Growth performance
broilers fed with two probiotic species put on more weight(Lan et al.,2003 )
weight gain significantly higher in probiotic fed birds(Kabir et al.,2004) .
inactivated probiotics have constructive actions on the production achievement (Huang et al.,2004).
Cont’d
values of giblets and dressing percentage elevated for probiotic fed broilers (Mahanjan et al.,1999)
Intestinal microbiota and morphology
Probiotics inhibited pathogens by dwelling on intestinal wall space(Kabir et al.,2005 )
Birds fed dietary B. subtilis for 28 days displayed better growth and prominent intestinal histologies. (Samanya and Yamauchi.,2002)
Chicks given Lactobacillus strains had less amount of coliforms in cecal grindings(Watkins and Kratzer.,1983 ).
Cont’d
L. salivarius 3d strain decreased the number of Clostridium perfringens and Salmonella enteritidis (Kizerwetter-Swida and Binek., 2009).
Probiotic species have an implicit action on regulation of intestinal microflora and pathogen occlusion (Higgins et al., 2007)
Immune response
Higher amount of antibody production(Kabir et al.,2005 )
Improved serum and intestinal antibodies to a foreign antigens in chickens (Haghighi et al.,2005)
Probiotics protected broilers against Eimeria acervulina infection even with a moderate dose (Dalloul et al.,2003)
Cont’d
Better local immune defenses against coccidiosis.
Splenocytes and cecal tonsil cells, STAT2 and STAT4 genes were greatly stimulated and the expression of STAT2, STAT4, IL-18, IFN-alpha, and IFN-gamma genes in cecal tonsil cells were up-regulated after treating with L. acidophilus DNA.
Additive probiotic supplements were ineffective on systemic IgG (Midilli et al.,2008 ).
Integrating Ayurveda into Parkinson’s Management: A Holistic ApproachAyurveda ForAll
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- Video recording of this lecture in English language: https://youtu.be/kqbnxVAZs-0
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Probiotics are live microorganisms that, when consumed in adequate amounts, confer health benefits. The document defines probiotics according to the FAO and WHO as live microorganisms that benefit the host. Common probiotic bacteria include Lactobacilli and Bifidobacteria, which are found naturally in the gut microbiota. Potential health benefits of probiotics may depend on the specific strains consumed.
Ankylosing Spondylitis the gut and the bugs: an integrative approach to treat...IFSMED
The document discusses the relationship between ankylosing spondylitis and gut health. It notes that subclinical gut inflammation is present in many spondyloarthropathy patients. Two types of gut inflammation are described - acute and chronic. The chronic type resembles Crohn's disease. Increased intestinal permeability is a key mechanism in spondyloarthropathis. Tight junctions regulate permeability and zonulin modulates this. The document discusses optimizing gut microbiota and permeability through probiotics, prebiotics, diet and supplements to help treat spondyloarthropathis through a gut-focused approach.
Probiotics are well known and routinely used additives in the main livestock species. They claim to improve gut health by stabilising gut flora being their effect reflected in a better overall health status, welfare and performance of the animals.
Probiotics are live microorganisms that support gut health. The gut contains 70% of the immune system, making a balanced gut microbiome important. Probiotics may be useful when medication, illness, stress, travel, or aging disrupt the balance of good and bad bacteria. Imbalances can cause issues like IBS, bloating, constipation or diarrhea. The document recommends probiotics containing multiple strains of bacteria or yeast, and highlights three probiotic supplements from Specialist Supplements containing different formulations to support gut health.
The document discusses probiotics, prebiotics, and synbiotics. It defines them as follows:
- Probiotics are live microorganisms that confer health benefits when consumed. They include bacteria like Lactobacillus and Bifidobacterium.
- Prebiotics are non-digestible food ingredients that promote the growth of beneficial bacteria. They include fibers like inulin and oligosaccharides.
- Synbiotics refer to products containing both probiotics and prebiotics to help probiotics survive and colonize the gut.
Probiotics, prebiotics, and synbiotics were defined. Probiotics are live microorganisms that provide health benefits when consumed. Prebiotics are non-digestible fibers that promote the growth of beneficial bacteria. Synbiotics combine probiotics and prebiotics. The document discussed the history of probiotic research from Metchnikoff's observations of Bulgarian longevity to current probiotic foods and strains. Potential health benefits of probiotics include managing diarrhea, allergies, and cholesterol, as well as supporting the immune system. Factors like processing, storage and the host's health impact probiotic survival.
The storyline behind the modern epidemic of inflammation driven disease goes as follows:
• Chronic degenerative conditions (Diseases of Civilization – DOCs) are on the rise and have overtaken infections as the major source of death and illness.
• This epidemiological transition is due, at least in part, to environmental changes that have increased the disease liability of genetic profiles that were previously benign.
• These DOCs are associated with increased systemic inflammation stemming from inappropriate stressor-response mechanisms.
• Much of this inflammation is generated and/or perpetuated by the gut-brain axis.
• Gut-brain axis derived inflammation leads to disruptions in psycho-neuro-immunological (PNI) balances.
• Pathophysiological mediators of PNI disturbances can be measured and treated.
• A cornerstone of said treatment is the regular consumption of a high quality multi-strain probiotic.
The carefully selected strains in Tri-Flora have been shown to:
• Decrease pro-inflammatory cytokines;
• Increase anti-inflammatory cytokine IL-10;
• Stimulate regulatory immune cells;
• Inhibit immune response to LPS (lipopolysaccharide) transduction;
• Improve intestinal barrier function;
• Enhance mucosal and systemic immune responses;
• Produce and deliver neurotransmitters such as GABA and serotonin.
And in so doing accomplish some very intriguing clinical feats:
1. Lessen symptoms of chronic fatigue syndrome;
2. Act as an adjunct to standard care in the treatment of Major Depressive Disorder;
3. Improve anxiety and reduce brain cell death; and
4. Help women lose weight.
It is for reasons such as this, that my most commonly recommended supplement for most people is a high quality probiotic. Tri-Flora by IP Formulas is my new favorite.
Get started today with the Gut flora & probiotic 11 to enjoy good health and a 15% discount...:0)
Simply, copy and paste the link below at your web browser address barpelase visit the l
http://totalhealthnow.eu.nspshop.com/probiotic_eleven_%2890%29.htm
>Since the ban of antibiotic growth promoters (AGPs) in the European Union, the industry has been looking for valid alternatives to improve health, immune status and performance in animal agriculture.
>The industry focuses on developing solutions that mimic the effects of AGPs. However, the exact mode of action of the AGPs to improve poultry performance is not fully understood.
Most AGPs alternatives try to prevent the proliferation of pathogenic bacteria and to modulate indigenous bacteria to improve immune status and performance.
>As an industry, we have made limited progress in improving gut health. Maybe we need to change the approach to find the most optimal solution.
>As part of a stable ecological system, pathogens per se do not represent a threat to animal health. The dynamic nature of the gastrointestinal microflora in chickens makes maintaining the right balance in the microbial ecosystem.
>Despite a large amount of scientific work has been done on the topic, a lack of consistent improvement has been registered.
>To improve gut health more consistently, a broader approach, involving a combination of nutrition, feed technology and husbandry management needs to be taken.
>In addition, gut-health is too complex to be solved from
only one point of view. Input should be obtained from different disciplines, including food technology, human nutrition, veterinary and human medical sciences.
>DSM will start an holistic program to come to tailor made solutions to improve the gut ecosystem with the objective of reducing the use of antibiotics in the poultry industry.
The document discusses how to choose a probiotic supplement. Key factors include choosing strains that are beneficial for your specific needs, selecting a probiotic that is effective for the desired health benefits, and choosing ones that are safe, acid/bile resistant, and reliably deliver live cultures. The document recommends considering strain origin, ability to colonize the gut, and individual dietary needs or preferences when selecting a probiotic supplement.
Leaky gut syndrome occurs when the intestines become porous, allowing undigested toxins and particles to pass through the intestinal wall. Maintaining a balance of good and bad bacteria in the gut is important for digestive and immune health. Probiotics can help treat leaky gut by repairing the intestinal lining and rebalancing gut bacteria. Studies show certain probiotic strains like Lactobacillus help improve leaky gut symptoms and intestinal permeability. The document recommends probiotic supplements containing multiple billion live cells of various tested strains to most effectively treat leaky gut.
The document summarizes an annual probiotic symposium held in Chennai, India in December 2016. It includes the following:
- An agenda for the symposium that covers definitions of probiotics, prebiotics, and synbiotics; the history of probiotics; the role of probiotics in gastrointestinal diseases; their functions and mechanisms of action; clinical applications in gastroenterology; dosage and safety issues; and conclusions.
- Presentations on the topics of probiotics in gastrointestinal diseases, their equilibrium in nature and the human body, and the gut flora.
- Evidence that certain probiotic strains like Lactobacillus and Bifidobacterium can reduce disease activity and symptoms
Many are confused what is the difference between prebiotics and probiotics. They are always surprised when they find out that they are completely different, but they complement each other very well.
Kefir contains more probiotic strains and a higher concentration of probiotics than yogurt. Kefir typically contains around 40 billion probiotic organisms per half cup serving, while Greek yogurt contains around 60 million CFU per gram. The probiotics in kefir are also more likely to colonize the intestines long-term compared to the transient bacteria in yogurt. However, both kefir and yogurt provide health benefits by maintaining digestive health and balancing intestinal microflora.
prebiotic and probiotic....., diffrent between prebiotic and probiotic , in food chemistry , and also food processing tecnology, A.D patel institute of tecnology, v.v nagar, gujrat,india,
Herbana Red Goji Juice Concentrate (Slideshare)guest33a24e
The document discusses the purported health benefits of goji berries, inulin fiber, chlorella, and moringa. It claims that goji berries improve eyesight, hair, libido, mood, sleep, energy levels and contain various minerals and amino acids. It also discusses how inulin fiber is a prebiotic that promotes the growth of healthy gut bacteria and may reduce cancer and cholesterol risks. Chlorella is claimed to help fight cancer and boost immunity. Moringa is said to prevent over 300 diseases and have anti-aging, antioxidant and general wellness benefits.
The document discusses the importance of gut microbiota and microbial diversity in gut health and disease. It notes that the gut is home to trillions of microorganisms that play a vital role in digestion, immunity, and overall health. A balanced gut microbiota supports digestive health, but disruptions to this balance through factors like antibiotics, poor diet, pollution, and stress can lead to gut dysbiosis and conditions like leaky gut syndrome. Maintaining a healthy gut microbiota through a fiber-rich diet, limiting sugars and processed foods, taking probiotics, and avoiding overuse of antibiotics is key for overall wellness.
The document discusses the health benefits of probiotic foods. It begins with a brief history of probiotics and defines them as live microorganisms that benefit the host. Probiotics can establish a healthy gut flora, produce antimicrobial substances, and boost immunity. They help treat conditions like antibiotic-associated diarrhea, hepatic encephalopathy, and H. pylori infections. The document examines the selection of probiotic strains and establishes their role in supporting digestive and overall health.
Probiotics are living microorganisms that provide health benefits when consumed in adequate amounts. They help maintain a healthy balance of bacteria in the gut and can aid in digestion, strengthen the immune system, and reduce risks of certain diseases. Common probiotic strains include Lactobacillus and Bifidobacterium species. Probiotics are available in foods like yogurt as well as supplements like tablets and capsules. Consuming probiotics may benefit those with digestive issues, weak immune systems, or frequent infections.
Probiotics- unfolding their potential in boosting poultry industryX S
Definition:
“Living microorganisms when conferred in sufficient amount on the host, will render beneficial effects on health.”(FAO/WHO)
Lactobacillus, Candida, Streptococcus, Enterococcus, Bifidobacterium, Aspergillus, and Saccharomyces spp.
History
Élie Metchnikoff (20th century)
Werner Kolath(1953)
Probiotics for poultry
Need of Probiotics?
Selection criteria
Probiotics in poultry industry
First decisive incident
Commercial vs. wild chicken
Selection criteria
Probiotic requirement in poultry (concept)
How probiotics act?
Maintain normal intestinal microflora
competitive exclusion and resistance
Change metabolism
speeding digestive enzyme activity
Perk up feed intake and digestion
Diminish bacterial enzyme activity and ammonia production
Stimulate the immune system
Evaluation of probiotics on poultry
Growth performance
Intestinal microbiota and morphology
Immune response
Meat quality/chicken caracass
Side effects(toxicity of ingredients)
Growth performance
broilers fed with two probiotic species put on more weight(Lan et al.,2003 )
weight gain significantly higher in probiotic fed birds(Kabir et al.,2004) .
inactivated probiotics have constructive actions on the production achievement (Huang et al.,2004).
Cont’d
values of giblets and dressing percentage elevated for probiotic fed broilers (Mahanjan et al.,1999)
Intestinal microbiota and morphology
Probiotics inhibited pathogens by dwelling on intestinal wall space(Kabir et al.,2005 )
Birds fed dietary B. subtilis for 28 days displayed better growth and prominent intestinal histologies. (Samanya and Yamauchi.,2002)
Chicks given Lactobacillus strains had less amount of coliforms in cecal grindings(Watkins and Kratzer.,1983 ).
Cont’d
L. salivarius 3d strain decreased the number of Clostridium perfringens and Salmonella enteritidis (Kizerwetter-Swida and Binek., 2009).
Probiotic species have an implicit action on regulation of intestinal microflora and pathogen occlusion (Higgins et al., 2007)
Immune response
Higher amount of antibody production(Kabir et al.,2005 )
Improved serum and intestinal antibodies to a foreign antigens in chickens (Haghighi et al.,2005)
Probiotics protected broilers against Eimeria acervulina infection even with a moderate dose (Dalloul et al.,2003)
Cont’d
Better local immune defenses against coccidiosis.
Splenocytes and cecal tonsil cells, STAT2 and STAT4 genes were greatly stimulated and the expression of STAT2, STAT4, IL-18, IFN-alpha, and IFN-gamma genes in cecal tonsil cells were up-regulated after treating with L. acidophilus DNA.
Additive probiotic supplements were ineffective on systemic IgG (Midilli et al.,2008 ).
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Kenny De Meirleir : ME/CFS, hydrogen sulfide and aberrant prion disease
1.
2. Myalgic encephalomyelitis:
A highly prevalent debilitating disease
• Persistent, debilitating fatigue associated with numerous physical and
neurocognitive symptoms
Disease severity can range from moderate to extremely severe: patients
bedridden for years, totally caregiver dependent
• Prevalence estimates: 0,3 to 0,6%; one million patients in the USA, two
million patients in Europe
This may just be the tip of the iceberg
• High socio-economic cost
Cost to the society estimated as approximately $16 billion in the USA, €20
billion in Europe
3. Intestinal disorders in ME patients
• Patients usually present with multiple intestinal symptoms including:
Nausea Abdominal pain
Poor appetite Abnormal bowel motility
Gastric reflux Bloating
• Inflammation of the gastrointestinal tract
• Marked alteration of the intestinal microbial flora
4. Alterations of intestinal microflora
(aerobes)
• Enterococcus and Streptococcus species are strongly over-represented in
ME patients :
Organisms Control ME patients p-value
E.coli 1.0 x 108 4.26 x 107 p=0.98
Enterococcus spp. 5.0 x 106 3.5 x 107 p<0.001
Streptococcus spp. 8.9 x 104 9.8 x 107 p<0.001
Henry Butt, University of Melbourne
5. Alterations of intestinal microflora
(anaerobes)
• Among anaerobic bacteria, Prevotella is the most consistently
overgrown bacteria :
Organisms Control ME patients p-value
Bacteroides spp. 3.2 x 1011 1.6 x 1011 p=0.39
Prevotella spp. 1.0 X 108 9.0 x 109 p< 0.001
Bifidobacterium spp. 6.0 x 108 5.5 x 109 p=0.001
Lactobacillus spp. 2.7 x 107 1.8 x 108 p=0.002
Henry Butt, University of Melbourne
6. Bacterial overgrowth correlates with
symptoms severity
• Enterococcus spp. counts correlate with symptom expression :
Symptoms r and p-values
Headache r=.17, p<0.01
Arm pain r=.20, p<0.003
Shoulder pain r=.15, p<0.04
Myalgia r=.20, p<0.003
Palpitations r=.16, p<0.02
Sleep disturbance r=.20, p<0.004
Henry Butt, University of Melbourne
7. Bacterial overgrowth correlates with
symptoms severity
• Streptococcus spp. counts correlate with symptom expression :
Symptoms r and p-values
Post Exertional fatigue r=.15, p<0.03
Photophobia r=.14, p<0.04
Mind going blank r=.17, p<0.01
Cervical gland lymphodynia r=.14 p<0.04
Palpitations r=.15, p<0.03
Dizziness/Faintness r=.14, p<0.05
Henry Butt, University of Melbourne
8. Hydrogen sulfide produced by bacteria
works as a potent toxin for the body
• Hydrogen sulfide (H2S) has important physiological functions...
H2S is produced by the cells and is an important gaseous signal molecule,
involved in regulation of blood pressure, neurotransmission, muscle relaxation
and regulation of inflammation
• ...but exogeneous exposure can be extremely toxic
In excess, H2S acts as a mitochondrial poison. It can directly inhibit enzymes
involved in the cellular production of energy. H2S also interferes with oxygen
transport by blocking hemoglobin in the red blood cells.
Enterococcus, Streptococcus, Prevotella are strong H2S producers
9. Cumulative effects of H2S and heavy metals
Gut Gut barrier Cell
Strep
t E
N Other gaseous
T
Mold E mediators : NO. CO.
Fungi R
O
ATP
H2S
E. coli
H2S Mitochondria
CH3 CH3
Bacteria
S S
CH3 CH3 M
S S PRPC PRPDX
M
M M
M
(metals)
10. Heavy metals interfere directly with energy
production
Extracellular
NO.
+
O2.- S S H S
-
R-S
Oxidase
. Cu2+ S
ONOO S S H
Plasmamembrane
Q10
Intracellular
Krebs cycle
NADH ATP
Adapted from James Morré 2006 J Inorg Biochem 100 2140-2149
11. Genetic and environmental factors
contribute to aberrant protein conformation
C
PR P PRPDX
Genetic Environmental Acquired
Mutations Heavy Metals PRP DX
13. Disease severity in ME is associated with
different physiological dysfunctions
I II III
“Pre-ME” Moderate disease Severe disease
Dysfunctions Abnormal faecal test, high H2S Abnormal faecal test, high H2S, Abnormal faecal test, high
exposure to heavy metals H2S, exposure to heavy metals
that has caused aberrant
protein conformation (APD)
Symptoms No fatigue, possible gastro- Fatigue, gastro-intestinal Strong fatigue, multiple
intestinal symptoms. Low VO2, symptoms symptoms
slow recovery.
May be asymptomatic
Treatment Restore the gut: probiotics Restore the gut: probiotics, Difficult. Gut restoration, metal
enterocoated antibiotics. chelation. Treatment of
Metal chelation, Zinc associated dysfunctions
supplementation (opportunistic infections).
Treatment of APD is still
experimental
Increasing immune dysregulations (depressed T and NK cells, Th17 activation,
opportunistic infections…)
14. Immune alterations resulting from
intestinal dysfunction
Protection against Dysbiosis causes a decrease
TH1 intracellular pathogens of CD8+ cells and TH1 immunity
cells (viruses, bacteria)
IL-12
IFN-g
Naïve IL-4 Protection against
TH2 extracellular pathogens
T cells
cells (parasites, bacteria)
TGF-b + IL-6 TH1 downregulation allows
increased TH2 and TH17
Local immunity
TH17 (mucosa, skin)
Protection against
cells fungi, bacteria
15. Consequences of altered immunity
• TH1 decrease favors the development of opportunistic viral infections
HHV-6, Epstein-Barr, parvovirus B19, enteroviruses
are found in ME patients. Gastro-intestinal mucosa
is a major site of infection
• TH2 increase favors the development of allergies
• TH17 increase promotes inflammation, autoimmunity, blood-brain
barrier disruption
Genetic background plays a role in TH17 upregulation
Polymorphisms of IL-17F, IL-6, TLR4, TGF-b genes
are associated with ME and other intestinal diseases
(Crohn’s disease, UC, IBS)
16. Patient evaluation
• Urine test for marker associated with H2S production
• Intestinal microflora evaluation
• Heavy metals analysis
• Presence of proteins with abnormal conformation
• Assays evaluating subsequent immune dysfunctions (immune
dysregulations, opportunistic infections...)
17. A marker associated with H2S production
can be measured with a simple urine test
1. Collect urine 2. Open tube containing 3. Add a few drops of urine
test reagent to the test reagent
4. Mix by shaking gently. 5. Observe color changes. Dark color = positive sample
Wait for two minutes
Negative or Moderate Severe
Pre-ME disease disease
18. A specific microbiological assay can
determine gut microflora populations
• Investigation of the microbial flora of the intestinal tract
- Quantifies major aerobic and anaerobic bacterial groups and yeast
- Focuses on dysbiosis (imbalance of the intestinal ecosytem) rather than
digestive analysis to ascertain gut integrity
• Challenge: keep anaerobic bacteria viable for analysis
- Validated oxygen-free, temperature controlled collection and shipping system
19. Microbiological assay : sample result
• Patient presents increased Streptococcus, Enterococcus, and Prevotella
20. Heavy metal analysis : sample result
• Patient presents mercury
and nickel intoxication
22. CONCLUSIONS
• Gastro-intestinal dysfunctions play a central role in the pathogenesis
of ME
• Dysbiosis detrimental effect mediated by increased production of H2S
• Immune dysfunctions and opportunistic infections arise as a
consequence of pre-existing intestinal problems
Once established, infections will contribute to the maintenance/aggravation of
the disease
23. Acknowledgements
• Henry Butt at the Bio21 Institute, University of Melbourne
• Marian Dix Lemle, Independent Researcher, Washington DC
Med Hypotheses. 2009 Jan;72(1):108-9. Epub 2008 Sep 16. Hypothesis: chronic
fatigue syndrome is caused by dysregulation of hydrogen sulfide metabolism. Lemle
MD.