Kawasaki disease is an acute febrile vasculitic syndrome that primarily affects children under 5 years old. It was first described in 1967 and is most common in East Asia. While the exact cause is unknown, it is believed not to be hereditary or contagious. Symptoms include fever for at least 5 days along with red eyes, rash, cracked lips/tongue, swollen hands/feet and lymph nodes. Treatment involves hospitalization, aspirin and intravenous gamma globulin to prevent complications like heart disease. Most children recover fully within weeks.

2. P R E S E N T E D B Y : S H A H I D H U S S A I N
P R E S E N T E D T O : M I S S M E H R E E N A B B A S I
Disease of infancy and
childhood

3. Kawaski disease
 Introduction
 Kawasaki disease is an acute febrile vasculitic
syndrome of early childhood
 The disorder has also been called mucocutaneous
lymph node syndrome
 Kawasaki disease was first described in 1967 by Dr
Tomisaku Kawasaki

4. Epidemiology
 The incidence of KD is greatest in children who live
in East Asia or are of Asian ancestry living in other
parts of the world
 In 1976, Melish et al first reported Kawasaki disease
in the United States
 higher in the Asian populations (in Japan
239.6/100,000 children < 5 years of age per year)
than in Europe, where the incidence ranges from 4.9
to 15.2/100,000/year in the same age group

5. Cont….
 Approximately 5000-6000 cases are reported each
year in japan
 Ontario has the highest rate of Kawasaki disease
outside of Asia, with a yearly incidence of 26.2 cases
per 100,000 population younger than 5 years

6. Cause
 The cause of Kawasaki disease is unknown
 It does not appear to be hereditary or contagious
 Because the illness frequently occurs in outbreaks
 It is very rare for more than one child in a family to
develop Kawasaki disease.

7. Sign and Symptoms
 Symptoms of Kawasaki disease include:
 A fever lasting at least 5 days
 Red eyes
 A body rash
 Swollen, red, cracked lips and tongue
 Swollen, red feet and hands
 Swollen lymph nodes in the neck

8. Conti….
 About a week after the fever breaks, the skin from
the fingers and toes may peel off, sometimes in large
pieces. When this happens, new, normal skin shows
below the peeling skin.

11. Diagnosis
 Kawasaki disease can be hard to diagnose, because
there is not a test for it
 Physicians make the diagnosis after carefully
examining a child, observing signs and symptoms
 Blood tests
 Urine tests

12. Treatment and Prevention
 Kawasaki disease is frequently treated in the
hospital, with a stay from a few days to a few weeks
 Some children may receive care at home without
hospitalization.
 Even though the cause of Kawasaki disease is
unknown, specific medications are known to be
beneficial
 Aspirin
 Intravenous gamma globulin

13. Cont…
 Kawasaki disease can't be prevented
 However, most children who have the disease
recover—usually within weeks of getting signs and
symptoms.