Kaposi's sarcoma is a malignant condition primarily affecting men, associated with human herpesvirus 8, and prevalent among immunosuppressed patients, particularly those with AIDS. It manifests as vascular nodules on the skin and internal organs, and its symptoms can cause significant emotional and physical distress. Treatment varies based on immune suppression and tumor characteristics, and historical data indicates a rise in cases linked to the AIDS epidemic from the 1980s onward.