Julio Licinio is globally known for his research in leptin and satiety feeling. Fifteen years back, he identified three Turkey people who were suffering from leptin deficiency which is actually a genetic disorder.
Julio Licinio has made significant research on "pharmacogenomics" nearby "exploration of sadness" and has disseminated book on both restorative issues. He has in like manner conveyed his critical research translational psychiatry and chunkiness where he has depicted the association between despondency weight and antidepressants.
Julio Licinio is still working on various researches related to depression and some major mental diseases. He contributed 240 papers, 21000 references, 12 books among others on depression. He understands an active mind is essential for a sound body so he headed with a professional team to conduct various modern experiments and clinical testing for the betterment of the people.
julio licinio,MD, FRANZCP, is Deputy Director, Translational Medicine and Head, Mind andBrain Theme at the South Australian Health and Medical Research Institute andStrategic Professor of Psychiatry, Flinders University.He is also Research Professor at University of Southern California, LosAngeles.
Julio licinio is the deputy director at SAHMRI and there he leads the mind and brain. He is specialized in pharmacogenomics. He is also expertise in biology of depression and has been editing books on both of these topics. He has published research on obesity and the link between depression, obesity and the antidepressants.
This PowerPoint presentation provides an overview of the field of somatics as it is taught in various training programs such as the Master's of Counselling and Applied Psychotherapy degree at the Jansen Newman Institute (Think Education) in Sydney.
This presentation has been initially developed for the 'Foundations of Wellbeing' course at the School Of Biomedical and Health Sciences (University of Western Sydney) and then modified for the 'Learning for Sustainable Living' online learning program (Course 5).
Psychosomatic and ecological causes of illness with a focus on cancerWerner Sattmann-Frese
This PowerPoint presentation developed in 2010 to be presented at a number of professional development lectures and workshops. It is also being used in a modified form at the Jansen Newman Institute's Master of Counselling and Applied Psychotherapy program (PSY616 - Working with Psychosomatic Signs and symptoms).
Julio Licinio has made significant research on "pharmacogenomics" nearby "exploration of sadness" and has disseminated book on both restorative issues. He has in like manner conveyed his critical research translational psychiatry and chunkiness where he has depicted the association between despondency weight and antidepressants.
Julio Licinio is still working on various researches related to depression and some major mental diseases. He contributed 240 papers, 21000 references, 12 books among others on depression. He understands an active mind is essential for a sound body so he headed with a professional team to conduct various modern experiments and clinical testing for the betterment of the people.
julio licinio,MD, FRANZCP, is Deputy Director, Translational Medicine and Head, Mind andBrain Theme at the South Australian Health and Medical Research Institute andStrategic Professor of Psychiatry, Flinders University.He is also Research Professor at University of Southern California, LosAngeles.
Julio licinio is the deputy director at SAHMRI and there he leads the mind and brain. He is specialized in pharmacogenomics. He is also expertise in biology of depression and has been editing books on both of these topics. He has published research on obesity and the link between depression, obesity and the antidepressants.
This PowerPoint presentation provides an overview of the field of somatics as it is taught in various training programs such as the Master's of Counselling and Applied Psychotherapy degree at the Jansen Newman Institute (Think Education) in Sydney.
This presentation has been initially developed for the 'Foundations of Wellbeing' course at the School Of Biomedical and Health Sciences (University of Western Sydney) and then modified for the 'Learning for Sustainable Living' online learning program (Course 5).
Psychosomatic and ecological causes of illness with a focus on cancerWerner Sattmann-Frese
This PowerPoint presentation developed in 2010 to be presented at a number of professional development lectures and workshops. It is also being used in a modified form at the Jansen Newman Institute's Master of Counselling and Applied Psychotherapy program (PSY616 - Working with Psychosomatic Signs and symptoms).
Hippocrates was the first Epidemiologist.
First expound the theory that diseases had natural, not supernatural, causes and that the body could heal itself.
Acupressure therapy, Acupuncture therapy, Chinese meridian, Foot reflection therapy, Heart meridian, Meridian charts, Meridian therapy, Weight control therapy
Professor Julio’s research area was mainly on Molecular Medicine, Genetics, Genomics, Endocrinology, Psychiatry (Incl. Psychotherapy) and Neurogenetics. His research on the essential endocrine and pharmacogenomic mechanisms at the line of obesity and depression have gained a noticeable name in scientific literature.
JulioLicinio passes on to Upstate record for completing each piece of medication based on academic as “Laraque-Arena”. His amazing experiences as a researcher and scientist with gloabal reputation in the medical world are really going to grow Upsate examination and academic wander.
It is Julio Licinio who made extraordinary research on psyche or mind for despondency and arrived at the conclusion that expanding the level of leptin helps incredibly diminishing the level of melancholy. He has demonstrated this with the assistance of a trial.
Julio Licinio concludes that an active mind is extremely essential to have a sound mind-set and thereby, a healthy body. His extraordinary research has proved very helpful to medical experts dealing with the cases of mental depression, treating them after understanding them completely.
On July 1, 2017, Dr. Julio Licinio has effectively supplanted Dr. David Duggan, a previous senior member of College of Medicine. While taking the charge of dignitary, he has additionally been pronounced a senior VP of Upstate University.
Hippocrates was the first Epidemiologist.
First expound the theory that diseases had natural, not supernatural, causes and that the body could heal itself.
Acupressure therapy, Acupuncture therapy, Chinese meridian, Foot reflection therapy, Heart meridian, Meridian charts, Meridian therapy, Weight control therapy
Professor Julio’s research area was mainly on Molecular Medicine, Genetics, Genomics, Endocrinology, Psychiatry (Incl. Psychotherapy) and Neurogenetics. His research on the essential endocrine and pharmacogenomic mechanisms at the line of obesity and depression have gained a noticeable name in scientific literature.
JulioLicinio passes on to Upstate record for completing each piece of medication based on academic as “Laraque-Arena”. His amazing experiences as a researcher and scientist with gloabal reputation in the medical world are really going to grow Upsate examination and academic wander.
It is Julio Licinio who made extraordinary research on psyche or mind for despondency and arrived at the conclusion that expanding the level of leptin helps incredibly diminishing the level of melancholy. He has demonstrated this with the assistance of a trial.
Julio Licinio concludes that an active mind is extremely essential to have a sound mind-set and thereby, a healthy body. His extraordinary research has proved very helpful to medical experts dealing with the cases of mental depression, treating them after understanding them completely.
On July 1, 2017, Dr. Julio Licinio has effectively supplanted Dr. David Duggan, a previous senior member of College of Medicine. While taking the charge of dignitary, he has additionally been pronounced a senior VP of Upstate University.
One major role of psychology is to improve the lives of the people.docxcherishwinsland
One major role of psychology is to improve the lives of the people we touch. Whether through research, service, or provision of primary or secondary health care, we look forward to the day when we can adequately prevent, diagnose, and treat diseases, and foster positive states of being in balance with others and the environment. This is not an easy task; a multitude of forces influences our health and the development of diseases.
As we strive to meet this challenge, the important role of culture in contributing to the maintenance of health and the etiology and treatment of disease has become increasingly clear. Although our goals of maintaining health and preventing and treating diseases may be the same across cultures, cultures vary in their perceptions of illness and their definitions of what is considered healthy and what is considered a disease. From anthropological and sociological perspectives, disease refers to a “malfunctioning or maladaptation of biologic and psychophysiologic processes in the individual” and illness refers to the “personal, interpersonal, and cultural reactions to disease or discomfort” (Kleinman, Eisenberg, & Good, 2006; p. 141). Thus, how we view health, disease, and illness, is strongly shaped by culture.
This chapter explores how cultural factors sway physical health and disease processes, and investigates our attempts to treat both psychological and sociological influences. We begin with an examination of cultural differences in the definition of health and present three indicators of health worldwide: life expectancy, infant mortality, and subjective well-being. We will then review the considerable amount of research concerning the relationship between culture and heart disease, other physical disease processes, eating disorders, obesity, and suicide. Next, we will explore differences in health care systems across countries. Finally, we will summarize the research in the form of a model of cultural influences on health.
CULTURAL DIFFERENCES IN THE DEFINITION OF HEALTH
Comparison Across Cultures
Before we look at how culture influences health and disease processes, we need to examine exactly what we mean by health. More than 60 years ago, the World Health Organization (WHO) developed a definition at the International Health Conference, at which 61 countries were represented. They defined health as “a state of complete physical, mental, and social well-being, and not merely the absence of disease or infirmity.” The WHO definition goes on further to say that “The enjoyment of the highest attainable standard of health is one of the fundamental rights of every human being, without distinction of race, religion, political beliefs or economic and social conditions” (World Health Organization, 1948). This definition of health is still used by the WHO today.
In the United States, our views of health have been heavily influenced by what many call the biomedical model of health and disease (Kleinman et al., 2006). Trad.
Anti psychiatry is like feedback for psychiatry that motivate for continue improvement in psychiatry. Everyone knows what is psychiatry, here is what is anti psychiatry. It helps to keep treatment standard and inward facilities up. Mainly opposing restrain against patients denial for treatment.
Similar to Julio Licinio Believes In Creative Approach Towards Health And Medicine (19)
Dr. Julio Licinio, the SUNY Distinguished Professor at State University of New York Upstate Medical University in Syracuse, New York for the departments of Pharmacology, Psychiatry, Medicine and Neuroscience & Physiology is working on the role of bullying and its effects on mental health.
You may praise his organizing habit, but it is a clear case of Obsessive Compulsive Disorder or OCD. Dr. Julio Licinio is working in this domain for the last 23 years to create awareness. To know more about this condition; we will share his thought and discussion here.
Dr. Julio Licinio, the renowned psychiatrist and the senior vice president for the Academic of Health Affairs and Professor of Department of Psychiatry of the College Of Medicine is working on this sector for long.
Psychological wellness and mental prosperity can customarily be a subject of discussion that many individuals want to stay away from, however these emotional sickness talks do the exact inverse.
Psychiatrist Julio Licinio reasoned that a dynamic personality is fundamental to remain rationally solid and maintain a strategic distance from conditions like despondency.
With the eye of Julio Licinio know about psychological wellness benefits in Australia gives a photo of the national reaction of the wellbeing and welfare benefit framework to the emotional wellness mind needs of Australians.
Here guiding a prompting master will work marvels and who can be a predominant choice than Julio Licinio. He is a significantly prestigious name and a pioneer of the cerebrum and mind subject and during the time has helped endless people go ahead with a typically stable life.
Dr. Julio Licinio brings to Upstate a record of accomplishment in every aspect of academic medicine,” Laraque-Arena.“His experience as a physician-scientist with a broad international reputation, together with his successful career and critical understanding of administrative leadership, clinical care, research, education and policy, will move Upstate forward and broaden our research and academic enterprise.”
Doctor Julio Licinio reports that the thyroid gland and the brain are not directly connected with each other. So, if you think that you have developed thyroid problem, get yourself medically diagnosed immediately.
Behavioral pharmaceutical is additionally a moderately new idea according Julio Licinio. It is an interdisciplinary field of study consolidating learning from fields like science, brain research and sociologies.
Julio Licinio is initially from Brazil but he lived for more than 2 decades in US, where he got his clinical and research training and education in psychiatry and endocrinology at University of Chicago, Cornell and Albert Einstein College of Medicine.
Julio Licinio believes it may take 40 years for humanity’s knowledge of the brain to match its understanding of cancer. “It’s not an organ like the liver that every cell is the same,” he says. “
Julio Licinio believes it may take 40 years for humanity’s knowledge of the brain to match its understanding of cancer. “It’s not an organ like the liver that every cell is the same,” he says. “
Professor Licinio trained in endocrinology and psychiatry at the University of Chicago and Cornell Medical Centre starting in 1984 while Professor Wong graduated from medical school in Brazil.
Professor Julio Licinio opens the First National Symposium on Translational Psychiatry, 4 -5 April 2011, at The John Curtin School of Medical Research, The Australian National University.
In a paper just published in Science, scientists from Rockefeller University in New York City show that humans can discriminate more than 1 trillion olfactory stimuli. It was previously thought that we could detect 10,000 odors.
ARTIFICIAL INTELLIGENCE IN HEALTHCARE.pdfAnujkumaranit
Artificial intelligence (AI) refers to the simulation of human intelligence processes by machines, especially computer systems. It encompasses tasks such as learning, reasoning, problem-solving, perception, and language understanding. AI technologies are revolutionizing various fields, from healthcare to finance, by enabling machines to perform tasks that typically require human intelligence.
These lecture slides, by Dr Sidra Arshad, offer a quick overview of physiological basis of a normal electrocardiogram.
Learning objectives:
1. Define an electrocardiogram (ECG) and electrocardiography
2. Describe how dipoles generated by the heart produce the waveforms of the ECG
3. Describe the components of a normal electrocardiogram of a typical bipolar leads (limb II)
4. Differentiate between intervals and segments
5. Enlist some common indications for obtaining an ECG
Study Resources:
1. Chapter 11, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 9, Human Physiology - From Cells to Systems, Lauralee Sherwood, 9th edition
3. Chapter 29, Ganong’s Review of Medical Physiology, 26th edition
4. Electrocardiogram, StatPearls - https://www.ncbi.nlm.nih.gov/books/NBK549803/
5. ECG in Medical Practice by ABM Abdullah, 4th edition
6. ECG Basics, http://www.nataliescasebook.com/tag/e-c-g-basics
Pulmonary Thromboembolism - etilogy, types, medical- Surgical and nursing man...VarunMahajani
Disruption of blood supply to lung alveoli due to blockage of one or more pulmonary blood vessels is called as Pulmonary thromboembolism. In this presentation we will discuss its causes, types and its management in depth.
Explore natural remedies for syphilis treatment in Singapore. Discover alternative therapies, herbal remedies, and lifestyle changes that may complement conventional treatments. Learn about holistic approaches to managing syphilis symptoms and supporting overall health.
Ozempic: Preoperative Management of Patients on GLP-1 Receptor Agonists Saeid Safari
Preoperative Management of Patients on GLP-1 Receptor Agonists like Ozempic and Semiglutide
ASA GUIDELINE
NYSORA Guideline
2 Case Reports of Gastric Ultrasound
New Directions in Targeted Therapeutic Approaches for Older Adults With Mantl...i3 Health
i3 Health is pleased to make the speaker slides from this activity available for use as a non-accredited self-study or teaching resource.
This slide deck presented by Dr. Kami Maddocks, Professor-Clinical in the Division of Hematology and
Associate Division Director for Ambulatory Operations
The Ohio State University Comprehensive Cancer Center, will provide insight into new directions in targeted therapeutic approaches for older adults with mantle cell lymphoma.
STATEMENT OF NEED
Mantle cell lymphoma (MCL) is a rare, aggressive B-cell non-Hodgkin lymphoma (NHL) accounting for 5% to 7% of all lymphomas. Its prognosis ranges from indolent disease that does not require treatment for years to very aggressive disease, which is associated with poor survival (Silkenstedt et al, 2021). Typically, MCL is diagnosed at advanced stage and in older patients who cannot tolerate intensive therapy (NCCN, 2022). Although recent advances have slightly increased remission rates, recurrence and relapse remain very common, leading to a median overall survival between 3 and 6 years (LLS, 2021). Though there are several effective options, progress is still needed towards establishing an accepted frontline approach for MCL (Castellino et al, 2022). Treatment selection and management of MCL are complicated by the heterogeneity of prognosis, advanced age and comorbidities of patients, and lack of an established standard approach for treatment, making it vital that clinicians be familiar with the latest research and advances in this area. In this activity chaired by Michael Wang, MD, Professor in the Department of Lymphoma & Myeloma at MD Anderson Cancer Center, expert faculty will discuss prognostic factors informing treatment, the promising results of recent trials in new therapeutic approaches, and the implications of treatment resistance in therapeutic selection for MCL.
Target Audience
Hematology/oncology fellows, attending faculty, and other health care professionals involved in the treatment of patients with mantle cell lymphoma (MCL).
Learning Objectives
1.) Identify clinical and biological prognostic factors that can guide treatment decision making for older adults with MCL
2.) Evaluate emerging data on targeted therapeutic approaches for treatment-naive and relapsed/refractory MCL and their applicability to older adults
3.) Assess mechanisms of resistance to targeted therapies for MCL and their implications for treatment selection
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We specializes in exporting high quality Research chemical, medical intermediate, Pharmaceutical chemicals and so on. Products are exported to USA, Canada, France, Korea, Japan,Russia, Southeast Asia and other countries.
Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...Oleg Kshivets
RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
CONCLUSIONS: 5YS of LCP after radical procedures significantly depended on: 1) PT early-invasive cancer; 2) PT N0--N12; 3) cell ratio factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) LC characteristics; 9) LC cell dynamics; 10) surgery type: lobectomy/pneumonectomy; 11) anthropometric data. Optimal diagnosis and treatment strategies for LC are: 1) screening and early detection of LC; 2) availability of experienced thoracic surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for LCP with unfavorable prognosis.
The prostate is an exocrine gland of the male mammalian reproductive system
It is a walnut-sized gland that forms part of the male reproductive system and is located in front of the rectum and just below the urinary bladder
Function is to store and secrete a clear, slightly alkaline fluid that constitutes 10-30% of the volume of the seminal fluid that along with the spermatozoa, constitutes semen
A healthy human prostate measures (4cm-vertical, by 3cm-horizontal, 2cm ant-post ).
It surrounds the urethra just below the urinary bladder. It has anterior, median, posterior and two lateral lobes
It’s work is regulated by androgens which are responsible for male sex characteristics
Generalised disease of the prostate due to hormonal derangement which leads to non malignant enlargement of the gland (increase in the number of epithelial cells and stromal tissue)to cause compression of the urethra leading to symptoms (LUTS
Flu Vaccine Alert in Bangalore Karnatakaaddon Scans
As flu season approaches, health officials in Bangalore, Karnataka, are urging residents to get their flu vaccinations. The seasonal flu, while common, can lead to severe health complications, particularly for vulnerable populations such as young children, the elderly, and those with underlying health conditions.
Dr. Vidisha Kumari, a leading epidemiologist in Bangalore, emphasizes the importance of getting vaccinated. "The flu vaccine is our best defense against the influenza virus. It not only protects individuals but also helps prevent the spread of the virus in our communities," he says.
This year, the flu season is expected to coincide with a potential increase in other respiratory illnesses. The Karnataka Health Department has launched an awareness campaign highlighting the significance of flu vaccinations. They have set up multiple vaccination centers across Bangalore, making it convenient for residents to receive their shots.
To encourage widespread vaccination, the government is also collaborating with local schools, workplaces, and community centers to facilitate vaccination drives. Special attention is being given to ensuring that the vaccine is accessible to all, including marginalized communities who may have limited access to healthcare.
Residents are reminded that the flu vaccine is safe and effective. Common side effects are mild and may include soreness at the injection site, mild fever, or muscle aches. These side effects are generally short-lived and far less severe than the flu itself.
Healthcare providers are also stressing the importance of continuing COVID-19 precautions. Wearing masks, practicing good hand hygiene, and maintaining social distancing are still crucial, especially in crowded places.
Protect yourself and your loved ones by getting vaccinated. Together, we can help keep Bangalore healthy and safe this flu season. For more information on vaccination centers and schedules, residents can visit the Karnataka Health Department’s official website or follow their social media pages.
Stay informed, stay safe, and get your flu shot today!
New Drug Discovery and Development .....NEHA GUPTA
The "New Drug Discovery and Development" process involves the identification, design, testing, and manufacturing of novel pharmaceutical compounds with the aim of introducing new and improved treatments for various medical conditions. This comprehensive endeavor encompasses various stages, including target identification, preclinical studies, clinical trials, regulatory approval, and post-market surveillance. It involves multidisciplinary collaboration among scientists, researchers, clinicians, regulatory experts, and pharmaceutical companies to bring innovative therapies to market and address unmet medical needs.
Acute scrotum is a general term referring to an emergency condition affecting the contents or the wall of the scrotum.
There are a number of conditions that present acutely, predominantly with pain and/or swelling
A careful and detailed history and examination, and in some cases, investigations allow differentiation between these diagnoses. A prompt diagnosis is essential as the patient may require urgent surgical intervention
Testicular torsion refers to twisting of the spermatic cord, causing ischaemia of the testicle.
Testicular torsion results from inadequate fixation of the testis to the tunica vaginalis producing ischemia from reduced arterial inflow and venous outflow obstruction.
The prevalence of testicular torsion in adult patients hospitalized with acute scrotal pain is approximately 25 to 50 percent
Tom Selleck Health: A Comprehensive Look at the Iconic Actor’s Wellness Journeygreendigital
Tom Selleck, an enduring figure in Hollywood. has captivated audiences for decades with his rugged charm, iconic moustache. and memorable roles in television and film. From his breakout role as Thomas Magnum in Magnum P.I. to his current portrayal of Frank Reagan in Blue Bloods. Selleck's career has spanned over 50 years. But beyond his professional achievements. fans have often been curious about Tom Selleck Health. especially as he has aged in the public eye.
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Introduction
Many have been interested in Tom Selleck health. not only because of his enduring presence on screen but also because of the challenges. and lifestyle choices he has faced and made over the years. This article delves into the various aspects of Tom Selleck health. exploring his fitness regimen, diet, mental health. and the challenges he has encountered as he ages. We'll look at how he maintains his well-being. the health issues he has faced, and his approach to ageing .
Early Life and Career
Childhood and Athletic Beginnings
Tom Selleck was born on January 29, 1945, in Detroit, Michigan, and grew up in Sherman Oaks, California. From an early age, he was involved in sports, particularly basketball. which played a significant role in his physical development. His athletic pursuits continued into college. where he attended the University of Southern California (USC) on a basketball scholarship. This early involvement in sports laid a strong foundation for his physical health and disciplined lifestyle.
Transition to Acting
Selleck's transition from an athlete to an actor came with its physical demands. His first significant role in "Magnum P.I." required him to perform various stunts and maintain a fit appearance. This role, which he played from 1980 to 1988. necessitated a rigorous fitness routine to meet the show's demands. setting the stage for his long-term commitment to health and wellness.
Fitness Regimen
Workout Routine
Tom Selleck health and fitness regimen has evolved. adapting to his changing roles and age. During his "Magnum, P.I." days. Selleck's workouts were intense and focused on building and maintaining muscle mass. His routine included weightlifting, cardiovascular exercises. and specific training for the stunts he performed on the show.
Selleck adjusted his fitness routine as he aged to suit his body's needs. Today, his workouts focus on maintaining flexibility, strength, and cardiovascular health. He incorporates low-impact exercises such as swimming, walking, and light weightlifting. This balanced approach helps him stay fit without putting undue strain on his joints and muscles.
Importance of Flexibility and Mobility
In recent years, Selleck has emphasized the importance of flexibility and mobility in his fitness regimen. Understanding the natural decline in muscle mass and joint flexibility with age. he includes stretching and yoga in his routine. These practices help prevent injuries, improve posture, and maintain mobilit
Title: Sense of Taste
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the structure and function of taste buds.
Describe the relationship between the taste threshold and taste index of common substances.
Explain the chemical basis and signal transduction of taste perception for each type of primary taste sensation.
Recognize different abnormalities of taste perception and their causes.
Key Topics:
Significance of Taste Sensation:
Differentiation between pleasant and harmful food
Influence on behavior
Selection of food based on metabolic needs
Receptors of Taste:
Taste buds on the tongue
Influence of sense of smell, texture of food, and pain stimulation (e.g., by pepper)
Primary and Secondary Taste Sensations:
Primary taste sensations: Sweet, Sour, Salty, Bitter, Umami
Chemical basis and signal transduction mechanisms for each taste
Taste Threshold and Index:
Taste threshold values for Sweet (sucrose), Salty (NaCl), Sour (HCl), and Bitter (Quinine)
Taste index relationship: Inversely proportional to taste threshold
Taste Blindness:
Inability to taste certain substances, particularly thiourea compounds
Example: Phenylthiocarbamide
Structure and Function of Taste Buds:
Composition: Epithelial cells, Sustentacular/Supporting cells, Taste cells, Basal cells
Features: Taste pores, Taste hairs/microvilli, and Taste nerve fibers
Location of Taste Buds:
Found in papillae of the tongue (Fungiform, Circumvallate, Foliate)
Also present on the palate, tonsillar pillars, epiglottis, and proximal esophagus
Mechanism of Taste Stimulation:
Interaction of taste substances with receptors on microvilli
Signal transduction pathways for Umami, Sweet, Bitter, Sour, and Salty tastes
Taste Sensitivity and Adaptation:
Decrease in sensitivity with age
Rapid adaptation of taste sensation
Role of Saliva in Taste:
Dissolution of tastants to reach receptors
Washing away the stimulus
Taste Preferences and Aversions:
Mechanisms behind taste preference and aversion
Influence of receptors and neural pathways
Impact of Sensory Nerve Damage:
Degeneration of taste buds if the sensory nerve fiber is cut
Abnormalities of Taste Detection:
Conditions: Ageusia, Hypogeusia, Dysgeusia (parageusia)
Causes: Nerve damage, neurological disorders, infections, poor oral hygiene, adverse drug effects, deficiencies, aging, tobacco use, altered neurotransmitter levels
Neurotransmitters and Taste Threshold:
Effects of serotonin (5-HT) and norepinephrine (NE) on taste sensitivity
Supertasters:
25% of the population with heightened sensitivity to taste, especially bitterness
Increased number of fungiform papillae
Couples presenting to the infertility clinic- Do they really have infertility...Sujoy Dasgupta
Dr Sujoy Dasgupta presented the study on "Couples presenting to the infertility clinic- Do they really have infertility? – The unexplored stories of non-consummation" in the 13th Congress of the Asia Pacific Initiative on Reproduction (ASPIRE 2024) at Manila on 24 May, 2024.
Julio Licinio Believes In Creative Approach Towards Health And Medicine
1. Julio Licinio Believes In Creative Approach Towards Health
And Medicine
Julio Licinio the name itself signifies a vast medical research over various disorders
in human health. Julio Licinio is a deputy director at South Australian Health and
Medical Research Institute (SAHMARI) where his basic research is of mind and
brain. He is actually a psychiatry who made the deep research on the causes of
depression. With its’ research, it has been found that 40% of depression cases are
caused due to hereditary quality.
Julio Licinio is also psychiatry in Adelaide at Flinders University, clinical professor
in Albuquerque at University of New Mexico School of Medicine, adjunct
professor in Houston at the University of Texas, and visiting professor in Braga at
the University of Minho. He is a founder of the John Curtin School of Medical
research. He is also preparing to publish three journals in the medical field as
Molecular Psychiarity, The Pharmacogenomics, and Translational Psychiatry.
2. He has made deep research on “pharmacogenomics” along with “biology of
depression” and has published book on both medical issues. He has also published
his substantial research translational psychiatry and obesity where he has described
the link between depression obesity and antidepressants. And, as per the Google
Scholar, he has achieved the position h-index of 65 with more than 21,000citations.
He has published total 12 books and more than 240 papers which are indexed in
Pubmed.
Scientific research made by JulioLicino with his colleagues was the first to imply
that leptin may be used as antidepressant effects. This concept was further carried
by many other groups. He has also proved that leptin effects in human are pro-
cognitive.
Julio Licinio is globally known for his research in leptin and satiety feeling. Fifteen
years back, he identified three Turkey people who were suffering from leptin
deficiency which is actually a genetic disorder. At that time, only these three were
having this disorder due to which they were over weighted. And, to cure this
disease he injected leptin in their body on daily basis and after ten months he found
that patient had lost almost half of their weight.
3. This made to discover that leptin is produced in a well organized way with different
circadian rhythm and pulsatility. As a result, it shows that leptin controls every
second rhythm of varied endicrive axes like the hypothalamic-pituitary-thyroid
axis, adrenal axis, and gonadal axis.
Hence, these were the incredible and innovative contribution of Julio Licinio
towards the medical world that has been made earlier. Apart, from these
contributions, many researches are still going on to throw varied disease related to
depression.
Visit our site for more information:
http://www.syracuse.com/health/index.ssf/2017/04/upstate_hires_new_medical_school_
dean_from_australia.html
https://medicine.yale.edu/psychiatry/newsandevents/archive/article.aspx?id=14761
http://upstateonline.info/static/April6-April132017/blog/story-1/index.html
http://www.upstate.edu/news/article.php?title=10612