Reading Group @ Kyoto University
Sheng Zhang, Rachel Rudinger, Kevin Duh, and Benjamin Van Durme. 2017. Ordinal Common-sense Inference. Transactions of the Association for Computational Linguistics (TACL) (To Appear)
Reading Group @ Kyoto University
Sheng Zhang, Rachel Rudinger, Kevin Duh, and Benjamin Van Durme. 2017. Ordinal Common-sense Inference. Transactions of the Association for Computational Linguistics (TACL) (To Appear)
Bayesian network structure estimation based on the Bayesian/MDL criteria when...Joe Suzuki
J. Suzuki. ``Bayesian network structure estimation based on the Bayesian/MDL criteria when both discrete and continuous variables are present". IEEE Data Compression Conference, pp. 307-316, Snowbird, Utah, April 2012.
Bayesian network structure estimation based on the Bayesian/MDL criteria when...Joe Suzuki
J. Suzuki. ``Bayesian network structure estimation based on the Bayesian/MDL criteria when both discrete and continuous variables are present". IEEE Data Compression Conference, pp. 307-316, Snowbird, Utah, April 2012.
Slide 1: Title Slide
Extrachromosomal Inheritance
Slide 2: Introduction to Extrachromosomal Inheritance
Definition: Extrachromosomal inheritance refers to the transmission of genetic material that is not found within the nucleus.
Key Components: Involves genes located in mitochondria, chloroplasts, and plasmids.
Slide 3: Mitochondrial Inheritance
Mitochondria: Organelles responsible for energy production.
Mitochondrial DNA (mtDNA): Circular DNA molecule found in mitochondria.
Inheritance Pattern: Maternally inherited, meaning it is passed from mothers to all their offspring.
Diseases: Examples include Leber’s hereditary optic neuropathy (LHON) and mitochondrial myopathy.
Slide 4: Chloroplast Inheritance
Chloroplasts: Organelles responsible for photosynthesis in plants.
Chloroplast DNA (cpDNA): Circular DNA molecule found in chloroplasts.
Inheritance Pattern: Often maternally inherited in most plants, but can vary in some species.
Examples: Variegation in plants, where leaf color patterns are determined by chloroplast DNA.
Slide 5: Plasmid Inheritance
Plasmids: Small, circular DNA molecules found in bacteria and some eukaryotes.
Features: Can carry antibiotic resistance genes and can be transferred between cells through processes like conjugation.
Significance: Important in biotechnology for gene cloning and genetic engineering.
Slide 6: Mechanisms of Extrachromosomal Inheritance
Non-Mendelian Patterns: Do not follow Mendel’s laws of inheritance.
Cytoplasmic Segregation: During cell division, organelles like mitochondria and chloroplasts are randomly distributed to daughter cells.
Heteroplasmy: Presence of more than one type of organellar genome within a cell, leading to variation in expression.
Slide 7: Examples of Extrachromosomal Inheritance
Four O’clock Plant (Mirabilis jalapa): Shows variegated leaves due to different cpDNA in leaf cells.
Petite Mutants in Yeast: Result from mutations in mitochondrial DNA affecting respiration.
Slide 8: Importance of Extrachromosomal Inheritance
Evolution: Provides insight into the evolution of eukaryotic cells.
Medicine: Understanding mitochondrial inheritance helps in diagnosing and treating mitochondrial diseases.
Agriculture: Chloroplast inheritance can be used in plant breeding and genetic modification.
Slide 9: Recent Research and Advances
Gene Editing: Techniques like CRISPR-Cas9 are being used to edit mitochondrial and chloroplast DNA.
Therapies: Development of mitochondrial replacement therapy (MRT) for preventing mitochondrial diseases.
Slide 10: Conclusion
Summary: Extrachromosomal inheritance involves the transmission of genetic material outside the nucleus and plays a crucial role in genetics, medicine, and biotechnology.
Future Directions: Continued research and technological advancements hold promise for new treatments and applications.
Slide 11: Questions and Discussion
Invite Audience: Open the floor for any questions or further discussion on the topic.
This pdf is about the Schizophrenia.
For more details visit on YouTube; @SELF-EXPLANATORY;
https://www.youtube.com/channel/UCAiarMZDNhe1A3Rnpr_WkzA/videos
Thanks...!
Multi-source connectivity as the driver of solar wind variability in the heli...Sérgio Sacani
The ambient solar wind that flls the heliosphere originates from multiple
sources in the solar corona and is highly structured. It is often described
as high-speed, relatively homogeneous, plasma streams from coronal
holes and slow-speed, highly variable, streams whose source regions are
under debate. A key goal of ESA/NASA’s Solar Orbiter mission is to identify
solar wind sources and understand what drives the complexity seen in the
heliosphere. By combining magnetic feld modelling and spectroscopic
techniques with high-resolution observations and measurements, we show
that the solar wind variability detected in situ by Solar Orbiter in March
2022 is driven by spatio-temporal changes in the magnetic connectivity to
multiple sources in the solar atmosphere. The magnetic feld footpoints
connected to the spacecraft moved from the boundaries of a coronal hole
to one active region (12961) and then across to another region (12957). This
is refected in the in situ measurements, which show the transition from fast
to highly Alfvénic then to slow solar wind that is disrupted by the arrival of
a coronal mass ejection. Our results describe solar wind variability at 0.5 au
but are applicable to near-Earth observatories.
This presentation explores a brief idea about the structural and functional attributes of nucleotides, the structure and function of genetic materials along with the impact of UV rays and pH upon them.
Professional air quality monitoring systems provide immediate, on-site data for analysis, compliance, and decision-making.
Monitor common gases, weather parameters, particulates.
Comparing Evolved Extractive Text Summary Scores of Bidirectional Encoder Rep...University of Maribor
Slides from:
11th International Conference on Electrical, Electronics and Computer Engineering (IcETRAN), Niš, 3-6 June 2024
Track: Artificial Intelligence
https://www.etran.rs/2024/en/home-english/
1. Jeffreys' and BDeu Priors for Model Selection
WITMSE 2016
Helsinki, Finland, September 20
Joe Suzuki
(prof-joe)
Joe Suzuki (Osaka Univ., Japan)
2. Goal and Contributions
[Goal]
Compare for model selection
• BDeu (Bayesian Dirichlet equivalent uniform)
• Jeffreys prior (T-K estimator)
[Contribution]
Mathematically Proves
3. Road Map
1. Bayesian Dirichlet Scores
2. BDeu and Jeffreys Scores
3. A Found Property and its Proof
4. Main Theorem
5. Regularity in Model Selection
6. Summary
19. Regularity in Model Selection
Fitness + Simplicity → optimal
(-1) x Likelihood + Penalty Term → min
Newton’s
Law of
Motion
Maxwell
Equations
If model A is better than model B w.r.t. fitness and simplicity,
model A should be chosen (regularity).
Information Criteria
LASSO
22. Those bounds utilize regularity
Campos and Ji 2011 figured out one (=nice)
but the bound is not efficient (experiments).
Designing Pruning rules for BDeu is HARDer.
because regularity cannot be assumed
23. Bayes Prior
Based on his/her Belief:
Nobody should reject it from a general point of view.
BDeu violates regularity
contradicts with Newton, Maxwell, Information Critreria, LASSO, etc.
People might notice that their beliefs have been
wrong, after knowing the new result in this paper.
24. Summary
The prior behind BDeu might have been based on a wrong belief
That contradicts regularity in model selection
Future Work: Consider NML and others in a similar way