2. INTRODUCTION
Jaundice, also known as hyperbilirubinemia.
Bile pigments: bilirubin & biliverdin
Normal serum bilirubin level: 0.3-1.0mg/dl
Conjugated : 0.1-0.3mg/dl
Unconjugated: 0.2-0.7mg/dl
Increase 3mg/dl ___ hyperbilirubinemia
3. Some bilirubin is bound to a certain protein (albumin) in the blood.
This type of bilirubin is called unconjugated, or indirect, bilirubin.
In the liver, bilirubin is changed into a form that your body can get
rid of. This is called conjugated bilirubin or direct bilirubin.
4. DEFINITION
Jaundice is yellowish discoloration of the skin, sclera,
and mucous membranes due to hyperbilirubinemia and
deposition of bile pigments.
6. HEMOLYTIC JAUNDICE :
It is due to an increased breakdown of RBC’s which produces an
increased amount of unconjugated bilirubin in the blood.
HEPATOCELLULAR JAUNDICE:
It is due to result from the liver altered ability to take up bilirubin
from the blood or to conjugate or excrete it. In Hepatocellular
disease the hepatocytes are damaged and leak bilirubin.
OBSTRUCTIVE JAUNDICE occurs as a result of an obstruction
in the bile duct. The obstruction prevents the excretion of
bilirubin into the intestine. Bilirubin will then back up into the
liver and subsequently into the bloodstream.
7. ETIOLOGY
Haemolysis (hemolytic anemia)
Viral hepatitis (A,B,C)
Viral infection (EBV Epstein–Barr virus, CMV)
Gallstones
Carcinoma of head of pancreas
Gallblader Cancer
Drugs : paraceptamol penicillin's, oral
contraceptives, chlorpromazine over dose
Alcohol.
Autoimmune disorders
8. CLINICAL MANIFESTATION
Yellowish discoloration of the skin, mucous membrane ,eyes. Nail
beds and tongue.
Light colored stool
Yellowish brown colour urine
Abdominal pain
Fever, chills
itchy skin
weight loss
10. MANAGEMENT
MEDICAL MANAGEMENT:
Antihistamine drugs (for itching)
Eg. Levocitrizine 5mg
avle 25mg
Sedative for restlessness and irritability
example- lorazepam, diazepam
Enema in constipation
Antibiotics
Antipyretics
Vitamin K and B-complex
11. DIETARY MANAGEMENT:
Advice the patient for restrict fat intake
Provide high protein diet
High carbohydrate diet
Provide plenty of fluids, juices
Give glucose water
12. NURSING MANAGEMENT:
Provide comfort to the patient.
Maintain fluid and electrolyte
balance to the patient.
Maintain input and output
chart.
Provide psychological support
to the patient.
Give health education