Seminar on ion channels, including ongoing research.

1. Ion channels: Clinical
Applications
-Yasaswini Arja
18-11-23

2. Table of Contents:
1.Introduction
2.Types
3. Clinical Applications
4. Ongoing Research
5. Conclusion.
6. Thank You!

3. Definition:
Ion channels are
transmembrane proteins
that allow the selective
entry of various Ions.
🔸️First discovered by
Bernard and Miledi
using “patch clamp”

4. Types of ion
channels:
Ligand gated. Voltage gated.
Ion channel
a. Acetyl Choline
receptor
b. Calcium Channels
c. Amelogenin
Opened by
Binding of effector Membrane depolarization

5. Clinical
Applications:
1. Cystic Fibrosis
2. Long QT Syndrome
3. Cancer Research
4. Pain Management

6. Ongoing Research:
Various institutions conducting research are:
USA 🇺🇸 John Hopkins University Cardiovascular: How ion
channels can lead to cardiac
arrhythmia.
GERMANY 🇩🇪 Max Planck Institute for
Biophysical chemistry
Structure and Functions: Using
advanced imaging techniques
(Optogenics)
INDIA 🇮🇳 NIMHANS, Bangalore Schizophrenia and Epilepsy.
UK 🇬🇧 Dr Frances Ashcroft
(University of Oxford)
Diabetes and the ATP sensitive
Potassium channels.

7. Sources:
The information for this
presentation was gathered
from.
DM Vasudevan
https://www.imperial.ac.uk
https://www.jhu.edu
https://nimhans.edu
https://www.biophys.mpg.de/en

8. Ion channels are the
mvp’s of our body, by
biologically modifying
them many diseases can
be controlled and treated!
Conclusion:

9. Thank You!