This document describes a study that connected medical students from Canada and Hong Kong using problem-based learning (PBL) over video conferencing. Students engaged in two PBL sessions discussing cases from each location with an expert facilitator providing guidance. Transcripts showed high student engagement and discussions of cultural differences and similarities in patient interactions. The study provides proof-of-concept that international PBL can work with technology and expert facilitation, though larger testing is still needed to fully understand implications for cross-cultural learning.