Iodine is essential for the production of thyroid hormones and is concentrated in glandular tissues like the thyroid, breasts, and salivary glands. It is absorbed from foods like iodized salt, seaweed, and fish, with the daily requirement being 150 mcg. Iodine deficiency can promote disorders like goiter and increase the risk of cancers. Iodine has many therapeutic actions including being antibacterial, antifungal, anticancer, and helping conditions like asthma, diabetes, and fibrocystic breast disease. It can be used as a diagnostic tool and to treat thyroid disorders as well as decreasing vascularity before thyroid surgery.

1. IODINE

2. 
Signal – birth of western medicine; goiter

Universal medicine

Every cell utilizes iodine; especially wbc

Iodine concentrates in the glandular
system

Thyroid, breasts, salivary glands, parotid,
pancreas, cerebrospinal fluid, brain,
stomach, skin, lacrimal glands

3. Iodine absorption & distribution
Iodide
Thyroid -3% =50 mg ; TSH - Uptake
Fat [700mg], muscle (650mg) = 70%
Skin – 20% helps in sweating
For the production of hormones - thyroid,
adrenals, ovaries, testicles

5. Sources of iodine
Iodized salt
Haddock, sea weeds, cod, perch
Daily requirements:
Diet -500mcg
Physiological requirement – 150 mcg
Pregnancy and lactation – 200 mcg

6. Iodine deficiency
Iodine deficiency disorders
Promotes cancer
Lack of iodine in early pregnancy causes – children with ADD
Prone to Thyroid illnesses, breast, ovary, prostrate cancers
Low iodine – hyperestrogenic states – free estogen levels

8. METABOLISM

10. Excretion

11. Iodine therapeutic actions
Alkalinizing
Antibacterial
Anticancer
Antifungal, viral
Disinfectant, sterilizer
Mucolytic
Diagnostic – graves disease, thyroid cancer
Thyroid ( goiter )and antithyroid actions ( graves, thyroid
storm)

12. Conditions treated
ADD
Asthma
Atherosclerosis
Fibrocystic breast disease
Copd
Diabetes
Keloids
Sebaceous cysts, ovarian cysts, parotid duct stones
Preoperative management of thyroidectomy – decreases
vascularity

13. Significant antioxidant effect
Prevents accumulation of malondialdehyde in breast tissues

14. Iodine, amiodarone - hypothyroidism
excess iodine – Na -I-
Wolf-Chaikoff Effect

15. Jod -basdow effect
Overproduction of thyroid hormone – iodine repletion
Causes:
Endemic goitre
Graves disease
Toxic multinodular goitre
Autonomous thyroid nodules in the elderly
Thyroid adenoma

16. Iodine therapeutic preparations
KI
Lugols iodine
Radioactive iodine
Betadine