There is now considerable evidence that musculoskeletal disorders (MSD) are caused by multiple, interacting factors across the work system. In practice, however, most investigations focus on the injured person and the immediate context. As a result, the response to MSDs is often focused on training, or retraining, individuals. This presentation will describe the development of an investigation toolkit designed to help shift the focus during investigations from the injured worker to the broader work system. The presentation will present an overview of the toolkit, and the feedback from OHS practitioners at three hospitals in Victoria using the toolkit. A case study application of the toolkit will be presented to demonstrate how the toolkit can help to develop a better understanding of the system-wide factors that contribute to MSDs. The strategies that were identified to improve the risk control measures following the investigation will also be discussed.