In this section, we describe Carbohydrates Biochemistry and most of the slides are cited from:
1- Lippincott's Illustrated Biochemistry
2- Harper's Biochemistry
3- U Satyrana Biochemistry
In this lecture, we present the main reactions of Kreb's cycle and its clinical importance.
Most of the slides are cited from Lippincott's illustrated Biochemistry and Satyrana Biochemistry.
Best Bishes,
Dr. Haroon
In this section, we describe Glycolysis and its clinical importance and most of the slides are cited from:
1- Lippincott Biochemistry 7th edition
2- Satyrana Biochemistry
3- Harper Biochemistry
In this section, we describe different types of receptors. Most of the slides are cited from Lippincott's Illustrated Review Biochemistry. Other references include:
U. Satyrana Biochemistry
Harper's Biochmeistry
In this section, we describe enzymes. Most of the slides are cited from:
1. Lippincott's Illustrated Review Biochemistry
2. U. Satyrana Biochemistry
3. Harper's Biochemistry
In this section, we describe digestion and absorption of Nucleic Acids and Most of the slides are cited from:
1. Lippincott's Illustrated Review Biochemistry
2. U. Satyran Biochemistry
Dr. Haroon
In this section, we describe Nucleic Acids (Biochemistry). Most of the slides are cited from:
1. Lippincott's Illustrated Review's Biochemistry
2. U. Satyrana Biochemistry
Dr. Haroon
In this section we describe nucleotides and most of the slides are cited from:
Lippincott's Illustrated Review Biochemistry
U. Satyrana Biochemistry
Dr. Haroon
In this section, we describe digestion and absorption of proteins.
Most of the slides are cited from:
1. Lippincott's Illustrated Review Biochemistry
2. U. Satyrana Biochemistry
Dr. Haroon
In this lecture, we present the main reactions of Kreb's cycle and its clinical importance.
Most of the slides are cited from Lippincott's illustrated Biochemistry and Satyrana Biochemistry.
Best Bishes,
Dr. Haroon
In this section, we describe Glycolysis and its clinical importance and most of the slides are cited from:
1- Lippincott Biochemistry 7th edition
2- Satyrana Biochemistry
3- Harper Biochemistry
In this section, we describe different types of receptors. Most of the slides are cited from Lippincott's Illustrated Review Biochemistry. Other references include:
U. Satyrana Biochemistry
Harper's Biochmeistry
In this section, we describe enzymes. Most of the slides are cited from:
1. Lippincott's Illustrated Review Biochemistry
2. U. Satyrana Biochemistry
3. Harper's Biochemistry
In this section, we describe digestion and absorption of Nucleic Acids and Most of the slides are cited from:
1. Lippincott's Illustrated Review Biochemistry
2. U. Satyran Biochemistry
Dr. Haroon
In this section, we describe Nucleic Acids (Biochemistry). Most of the slides are cited from:
1. Lippincott's Illustrated Review's Biochemistry
2. U. Satyrana Biochemistry
Dr. Haroon
In this section we describe nucleotides and most of the slides are cited from:
Lippincott's Illustrated Review Biochemistry
U. Satyrana Biochemistry
Dr. Haroon
In this section, we describe digestion and absorption of proteins.
Most of the slides are cited from:
1. Lippincott's Illustrated Review Biochemistry
2. U. Satyrana Biochemistry
Dr. Haroon
In this section, we describe plasma proteins. Most of the slides are cited from:
1. Lippincott's illustrated Review Biochemistry
2. Harper's Biochemistry
3. U. Satyrana Biochemistry
In this section, we describe proteins biochemistry. Most of the slides are cited from:
1. Lippincott's Illustrated Review Biochemistry
2. U Satyran Biochemistry
3. Harper's Biochemistry
Dr. Haroon
In this presentation, we describe drugs used for allergic rhinitis and cough and most of the slides are cited from:
1. Lippincott's Pharmacology
2. KD Triphati Pharmacology
2. Basic Pharmacology
For further slides, you can email me at: haroonstanikzai1@gmail.com
Thank you
Dr. Haroon
In this section, we describe peptides and most of the slides are cited from:
1- Lippincott's Illustrated Review Biochemistry
2- Harper's Biochemistry
3- U. Satyr Ana Biochemistry
In this section We describe drugs used in Asthma and COPD and Most of the slides are prescribed from Lippincott's Pharmacology. Other references include:
1. Kd triphati Pharmacology
2. Basic Pharmacology
In this section, we describe Compound Lipids and most of the slides are cited from:
1- Lippincott's Illustrated Biochemistry
2- Harper's Biochemistry
3- Cheter-jee Biochemistry
Dr Haroon
n this section, we describe Drugs used in Vomiting and most of the slides are cited from:
1- Lippincott's Illustrated Biochemistry
2- Harper's Biochemistry
3- Cheter-jee Biochemistry
Dr Haroon
In this section, we describe Drugs used in Constipation and Diarrhea and most of the slides are cited from:
1- Lippincott's Illustrated Biochemistry
2- Harper's Biochemistry
3- Cheter-jee Biochemistry
Dr Haroon
In this section, we describe Digestion and Absorption of Lipids and most of the slides are cited from:
1- Lippincott's Illustrated Biochemistry
2- Harper's Biochemistry
3- Cheter-jee Biochemistry
Dr Haroon
In this section, we describe Compound Lipids and most of the slides are cited from:
1- Lippincott's Illustrated Biochemistry
2- Harper's Biochemistry
3- Cheter-jee Biochemistry
Dr Haroon
In this section, we describe drugs used for peptic ulcer diseases.
Most of the slides are cited from:
1- Lippincott's Illustrated Pharmacology
2- KD Triphati Pharmacology
In this section, we describe Compound Lipids and most of the slides are cited from:
1- Lippincott's Illustrated Biochemistry
2- Harper's Biochemistry
3- Cheter-jee Biochemistry
Dr Haroon
In this presentation, we describe Anti-Histamine drugs along with histamine physiology.
Most slides are cited from Lippincott's Pharmacology
Other references include:
Kd Triphati Pharmacology
Thank you,
In this section, we describe Introduction to Lipids and most of the slides are cited from:
1- Lippincott's Illustrated Biochemistry
2- Harper's Biochemistry
3- Cheter-jee Biochemistry
Dr Haroon
In this section, we describe:
- Digestion and Absorption of Carbohydrates
Most of the slides are cited from:
1. Lippincott's Biochemistry
2. Stayaran's Biochemistry
3. Jaypee Biochemistry
In this section, we describe Disaccharides and most of the slides are cited from:
1- Lippincott's Illustrated Biochemistry
2- Harper's Biochemistry
3- Cheter-jee Biochemistry
In this section, we describe Carbohydrates Biochemistry and most of the slides are cited from:
1- Lippincott's Illustrated Biochemistry
2- Harper's Biochemistry
3- Cheter-jee Biochemistry
Dr Haroon
In this section, we describe Important monosaccharides and most of the slides are cited from:
1- Lippincott's Illustrated Biochemistry
2- Harper's Biochemistry
3- Cheter-jee Biochemistry
Dr Haroon
In this section, we describe Reactions of Monosaccharides and most of the slides are cited from:
1- Lippincott's Illustrated Biochemistry
2- Harper's Biochemistry
3- U Satyrana Biochemistry
In this section, we describe structural aspects of monosaccharides and most of the slides are cited from:
1- Lippincott's Illustrated Biochemistry
2- Harper's Biochemistry
3- U Satyrana Biochemistry
Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
In this section, we describe plasma proteins. Most of the slides are cited from:
1. Lippincott's illustrated Review Biochemistry
2. Harper's Biochemistry
3. U. Satyrana Biochemistry
In this section, we describe proteins biochemistry. Most of the slides are cited from:
1. Lippincott's Illustrated Review Biochemistry
2. U Satyran Biochemistry
3. Harper's Biochemistry
Dr. Haroon
In this presentation, we describe drugs used for allergic rhinitis and cough and most of the slides are cited from:
1. Lippincott's Pharmacology
2. KD Triphati Pharmacology
2. Basic Pharmacology
For further slides, you can email me at: haroonstanikzai1@gmail.com
Thank you
Dr. Haroon
In this section, we describe peptides and most of the slides are cited from:
1- Lippincott's Illustrated Review Biochemistry
2- Harper's Biochemistry
3- U. Satyr Ana Biochemistry
In this section We describe drugs used in Asthma and COPD and Most of the slides are prescribed from Lippincott's Pharmacology. Other references include:
1. Kd triphati Pharmacology
2. Basic Pharmacology
In this section, we describe Compound Lipids and most of the slides are cited from:
1- Lippincott's Illustrated Biochemistry
2- Harper's Biochemistry
3- Cheter-jee Biochemistry
Dr Haroon
n this section, we describe Drugs used in Vomiting and most of the slides are cited from:
1- Lippincott's Illustrated Biochemistry
2- Harper's Biochemistry
3- Cheter-jee Biochemistry
Dr Haroon
In this section, we describe Drugs used in Constipation and Diarrhea and most of the slides are cited from:
1- Lippincott's Illustrated Biochemistry
2- Harper's Biochemistry
3- Cheter-jee Biochemistry
Dr Haroon
In this section, we describe Digestion and Absorption of Lipids and most of the slides are cited from:
1- Lippincott's Illustrated Biochemistry
2- Harper's Biochemistry
3- Cheter-jee Biochemistry
Dr Haroon
In this section, we describe Compound Lipids and most of the slides are cited from:
1- Lippincott's Illustrated Biochemistry
2- Harper's Biochemistry
3- Cheter-jee Biochemistry
Dr Haroon
In this section, we describe drugs used for peptic ulcer diseases.
Most of the slides are cited from:
1- Lippincott's Illustrated Pharmacology
2- KD Triphati Pharmacology
In this section, we describe Compound Lipids and most of the slides are cited from:
1- Lippincott's Illustrated Biochemistry
2- Harper's Biochemistry
3- Cheter-jee Biochemistry
Dr Haroon
In this presentation, we describe Anti-Histamine drugs along with histamine physiology.
Most slides are cited from Lippincott's Pharmacology
Other references include:
Kd Triphati Pharmacology
Thank you,
In this section, we describe Introduction to Lipids and most of the slides are cited from:
1- Lippincott's Illustrated Biochemistry
2- Harper's Biochemistry
3- Cheter-jee Biochemistry
Dr Haroon
In this section, we describe:
- Digestion and Absorption of Carbohydrates
Most of the slides are cited from:
1. Lippincott's Biochemistry
2. Stayaran's Biochemistry
3. Jaypee Biochemistry
In this section, we describe Disaccharides and most of the slides are cited from:
1- Lippincott's Illustrated Biochemistry
2- Harper's Biochemistry
3- Cheter-jee Biochemistry
In this section, we describe Carbohydrates Biochemistry and most of the slides are cited from:
1- Lippincott's Illustrated Biochemistry
2- Harper's Biochemistry
3- Cheter-jee Biochemistry
Dr Haroon
In this section, we describe Important monosaccharides and most of the slides are cited from:
1- Lippincott's Illustrated Biochemistry
2- Harper's Biochemistry
3- Cheter-jee Biochemistry
Dr Haroon
In this section, we describe Reactions of Monosaccharides and most of the slides are cited from:
1- Lippincott's Illustrated Biochemistry
2- Harper's Biochemistry
3- U Satyrana Biochemistry
In this section, we describe structural aspects of monosaccharides and most of the slides are cited from:
1- Lippincott's Illustrated Biochemistry
2- Harper's Biochemistry
3- U Satyrana Biochemistry
Title: Sense of Smell
Presenter: Dr. Faiza, Assistant Professor of Physiology
Qualifications:
MBBS (Best Graduate, AIMC Lahore)
FCPS Physiology
ICMT, CHPE, DHPE (STMU)
MPH (GC University, Faisalabad)
MBA (Virtual University of Pakistan)
Learning Objectives:
Describe the primary categories of smells and the concept of odor blindness.
Explain the structure and location of the olfactory membrane and mucosa, including the types and roles of cells involved in olfaction.
Describe the pathway and mechanisms of olfactory signal transmission from the olfactory receptors to the brain.
Illustrate the biochemical cascade triggered by odorant binding to olfactory receptors, including the role of G-proteins and second messengers in generating an action potential.
Identify different types of olfactory disorders such as anosmia, hyposmia, hyperosmia, and dysosmia, including their potential causes.
Key Topics:
Olfactory Genes:
3% of the human genome accounts for olfactory genes.
400 genes for odorant receptors.
Olfactory Membrane:
Located in the superior part of the nasal cavity.
Medially: Folds downward along the superior septum.
Laterally: Folds over the superior turbinate and upper surface of the middle turbinate.
Total surface area: 5-10 square centimeters.
Olfactory Mucosa:
Olfactory Cells: Bipolar nerve cells derived from the CNS (100 million), with 4-25 olfactory cilia per cell.
Sustentacular Cells: Produce mucus and maintain ionic and molecular environment.
Basal Cells: Replace worn-out olfactory cells with an average lifespan of 1-2 months.
Bowman’s Gland: Secretes mucus.
Stimulation of Olfactory Cells:
Odorant dissolves in mucus and attaches to receptors on olfactory cilia.
Involves a cascade effect through G-proteins and second messengers, leading to depolarization and action potential generation in the olfactory nerve.
Quality of a Good Odorant:
Small (3-20 Carbon atoms), volatile, water-soluble, and lipid-soluble.
Facilitated by odorant-binding proteins in mucus.
Membrane Potential and Action Potential:
Resting membrane potential: -55mV.
Action potential frequency in the olfactory nerve increases with odorant strength.
Adaptation Towards the Sense of Smell:
Rapid adaptation within the first second, with further slow adaptation.
Psychological adaptation greater than receptor adaptation, involving feedback inhibition from the central nervous system.
Primary Sensations of Smell:
Camphoraceous, Musky, Floral, Pepperminty, Ethereal, Pungent, Putrid.
Odor Detection Threshold:
Examples: Hydrogen sulfide (0.0005 ppm), Methyl-mercaptan (0.002 ppm).
Some toxic substances are odorless at lethal concentrations.
Characteristics of Smell:
Odor blindness for single substances due to lack of appropriate receptor protein.
Behavioral and emotional influences of smell.
Transmission of Olfactory Signals:
From olfactory cells to glomeruli in the olfactory bulb, involving lateral inhibition.
Primitive, less old, and new olfactory systems with different path
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Ethanol (CH3CH2OH), or beverage alcohol, is a two-carbon alcohol
that is rapidly distributed in the body and brain. Ethanol alters many
neurochemical systems and has rewarding and addictive properties. It
is the oldest recreational drug and likely contributes to more morbidity,
mortality, and public health costs than all illicit drugs combined. The
5th edition of the Diagnostic and Statistical Manual of Mental Disorders
(DSM-5) integrates alcohol abuse and alcohol dependence into a single
disorder called alcohol use disorder (AUD), with mild, moderate,
and severe subclassifications (American Psychiatric Association, 2013).
In the DSM-5, all types of substance abuse and dependence have been
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from mild to severe. A diagnosis of AUD requires that at least two of
the 11 DSM-5 behaviors be present within a 12-month period (mild
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The four main behavioral effects of AUD are impaired control over
drinking, negative social consequences, risky use, and altered physiological
effects (tolerance, withdrawal). This chapter presents an overview
of the prevalence and harmful consequences of AUD in the U.S.,
the systemic nature of the disease, neurocircuitry and stages of AUD,
comorbidities, fetal alcohol spectrum disorders, genetic risk factors, and
pharmacotherapies for AUD.
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There are a number of conditions that present acutely, predominantly with pain and/or swelling
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Testicular torsion refers to twisting of the spermatic cord, causing ischaemia of the testicle.
Testicular torsion results from inadequate fixation of the testis to the tunica vaginalis producing ischemia from reduced arterial inflow and venous outflow obstruction.
The prevalence of testicular torsion in adult patients hospitalized with acute scrotal pain is approximately 25 to 50 percent